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Extract from the Register of European Patents

EP About this file: EP1603886

EP1603886 - 4-SUBSTITUTED-5-CYANO-1H-PYRIMIDIN-6-(THI)ONES AS GSK-3 INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  25.12.2009
Database last updated on 28.03.2026
Most recent event   Tooltip07.10.2011Lapse of the patent in a contracting state
New state(s): CY, TR		published on 09.11.2011  [2011/45]
Applicant(s)For all designated states
VERTEX PHARMACEUTICALS INCORPORATED
130 Waverly Street
Cambridge, MA 02139-4242 / US
[2005/50]
Inventor(s)01 / MOON, Young-Choon
11 Edgewood Drive
Belle Mead, NJ 08502-5538 / US
 [2005/50]
Representative(s)Minderop, Ralph H.
Cohausz & Florack
Patent- und Rechtsanwälte
Partnerschaftsgesellschaft mbB
Bleichstrasse 14
40211 Düsseldorf / DE
[N/P]
Former [2005/50]Minderop, Ralph H.
COHAUSZ & FLORACK Patent- und Rechtsanwälte Bleichstrasse 14
40211 Düsseldorf / DE
Application number, filing date04720503.412.03.2004
[2005/50]
WO2004US07801
Priority number, dateUS20030454878P12.03.2003         Original published format: US 454878 P
[2005/50]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2004080977
Date:23.09.2004
Language:EN
[2004/39]
Type: A1 Application with search report 
No.:EP1603886
Date:14.12.2005
Language:EN
The application published by WIPO in one of the EPO official languages on 23.09.2004 takes the place of the publication of the European patent application.
[2005/50]
Type: B1 Patent specification 
No.:EP1603886
Date:18.02.2009
Language:EN
[2009/08]
Search report(s)International search report - published on:EP23.09.2004
ClassificationIPC:C07D239/36, C07D239/56, C07D405/04, C07D417/04, C07D403/04, C07D401/04, A61K31/513
[2005/50]
CPC:
C07D239/36 (EP,US); C07D239/56 (EP,US); C07D401/04 (EP,US);
C07D403/04 (EP,US); C07D405/04 (EP,US); C07D417/04 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2005/50]
Extension statesAL04.10.2005
LT04.10.2005
LV04.10.2005
MK04.10.2005
TitleGerman:4-SUBSTITUIRTE-5-CYANO-1H-PYRIMIDIN-6-(TH)IONES ALS ALS GSK-3-HEMMER[2005/50]
English:4-SUBSTITUTED-5-CYANO-1H-PYRIMIDIN-6-(THI)ONES AS GSK-3 INHIBITORS[2005/50]
French:5-CYANO-1H-PYRIMIDIN-6-(THI)ONES SUBSTITUES EN 4, UTILISES EN TANT QU'INHIBITEURS DE GSK-3[2005/50]
Entry into regional phase04.10.2005National basic fee paid 
04.10.2005Designation fee(s) paid 
04.10.2005Examination fee paid 
Examination procedure04.10.2005Examination requested  [2005/50]
18.09.2006Despatch of a communication from the examining division (Time limit: M06)
30.01.2007Reply to a communication from the examining division
20.06.2008Despatch of a communication from the examining division (Time limit: M04)
26.06.2008Reply to a communication from the examining division
25.08.2008Communication of intention to grant the patent
18.12.2008Fee for grant paid
18.12.2008Fee for publishing/printing paid
Opposition(s)19.11.2009No opposition filed within time limit [2010/04]
Fees paidRenewal fee
24.03.2006Renewal fee patent year 03
28.03.2007Renewal fee patent year 04
27.03.2008Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT18.02.2009
BE18.02.2009
CY18.02.2009
CZ18.02.2009
DK18.02.2009
EE18.02.2009
FI18.02.2009
PL18.02.2009
RO18.02.2009
SI18.02.2009
SK18.02.2009
TR18.02.2009
IE12.03.2009
LU12.03.2009
MC31.03.2009
BG18.05.2009
SE18.05.2009
GR19.05.2009
ES29.05.2009
PT27.07.2009
HU19.08.2009
[2011/44]
Former [2011/32]AT18.02.2009
BE18.02.2009
CZ18.02.2009
DK18.02.2009
EE18.02.2009
FI18.02.2009
PL18.02.2009
RO18.02.2009
SI18.02.2009
SK18.02.2009
IE12.03.2009
LU12.03.2009
MC31.03.2009
BG18.05.2009
SE18.05.2009
GR19.05.2009
ES29.05.2009
PT27.07.2009
HU19.08.2009
Former [2011/21]AT18.02.2009
BE18.02.2009
CZ18.02.2009
DK18.02.2009
EE18.02.2009
FI18.02.2009
PL18.02.2009
RO18.02.2009
SI18.02.2009
SK18.02.2009
IE12.03.2009
LU12.03.2009
MC31.03.2009
BG18.05.2009
SE18.05.2009
GR19.05.2009
ES29.05.2009
PT27.07.2009
Former [2010/50]AT18.02.2009
BE18.02.2009
CZ18.02.2009
DK18.02.2009
EE18.02.2009
FI18.02.2009
PL18.02.2009
RO18.02.2009
SI18.02.2009
SK18.02.2009
IE12.03.2009
MC31.03.2009
BG18.05.2009
SE18.05.2009
GR19.05.2009
ES29.05.2009
PT27.07.2009
Former [2010/09]AT18.02.2009
BE18.02.2009
CZ18.02.2009
DK18.02.2009
EE18.02.2009
FI18.02.2009
PL18.02.2009
RO18.02.2009
SI18.02.2009
SK18.02.2009
IE12.03.2009
MC31.03.2009
BG18.05.2009
SE18.05.2009
ES29.05.2009
PT27.07.2009
Former [2010/07]AT18.02.2009
BE18.02.2009
CZ18.02.2009
DK18.02.2009
EE18.02.2009
FI18.02.2009
PL18.02.2009
RO18.02.2009
SI18.02.2009
SK18.02.2009
IE12.03.2009
MC31.03.2009
SE18.05.2009
ES29.05.2009
PT27.07.2009
Former [2009/50]AT18.02.2009
BE18.02.2009
CZ18.02.2009
DK18.02.2009
EE18.02.2009
FI18.02.2009
PL18.02.2009
RO18.02.2009
SI18.02.2009
SK18.02.2009
MC31.03.2009
SE18.05.2009
ES29.05.2009
PT27.07.2009
Former [2009/47]AT18.02.2009
BE18.02.2009
DK18.02.2009
FI18.02.2009
PL18.02.2009
SI18.02.2009
MC31.03.2009
SE18.05.2009
ES29.05.2009
Former [2009/46]AT18.02.2009
BE18.02.2009
DK18.02.2009
FI18.02.2009
PL18.02.2009
SI18.02.2009
SE18.05.2009
ES29.05.2009
Former [2009/44]AT18.02.2009
BE18.02.2009
FI18.02.2009
PL18.02.2009
SI18.02.2009
SE18.05.2009
ES29.05.2009
Former [2009/41]AT18.02.2009
FI18.02.2009
PL18.02.2009
SI18.02.2009
SE18.05.2009
ES29.05.2009
Former [2009/36]FI18.02.2009
SI18.02.2009
ES29.05.2009
Former [2009/35]ES29.05.2009
Cited inInternational search[X]   DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; ABDEL-MEGID, M. ET AL: "Synthesis of bioactive aza-heterocyclic systems derived from novel biheterocyclic enone", XP002289504, retrieved from STN Database accession no. 2003:190837 [X] 1 * abstract *
 [X]   INTERNATIONAL JOURNAL OF CHEMISTRY , 12(4), 287-296 CODEN: INJCEW, 2002
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.