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Extract from the Register of European Patents

EP About this file: EP1652925

EP1652925 - IgM PRODUCTION BY TRANSFORMED CELLS AND METHODS FOR QUANTIFYING SAID IgM PRODUCTION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  14.10.2011
Database last updated on 02.09.2024
Most recent event   Tooltip04.10.2013Lapse of the patent in a contracting state
New state(s): HU		published on 06.11.2013  [2013/45]
Applicant(s)For all designated states
CHUGAI SEIYAKU KABUSHIKI KAISHA
5-1, Ukima 5-chome, Kita-ku
Tokyo, 115-8543 / JP
[2007/22]
Former [2006/18]For all designated states
CHUGAI SEIYAKU KABUSHIKI KAISHA
5-1, Ukima 5-chome, Kita-ku
Tokyo, 115-8543 / JP
For all designated states
Irie, Reiko
17624 Tramonto Drive
Pacific Palisades, CA 90272 / US
Inventor(s)01 / IRIE, Reiko
17624, Tramonto Drive
Pacific Palisades, California 90272 / US
02 / TSUNODA, Hiroyuki, CHUGAI SEIYAKU KABUSHIKI KAISHA
135, Komakado 1-chome
Gotenba-shi, Shizuoka 412-0038 / JP
03 / IGAWA, Tomoyuki, CHUGAI SEIYAKU KABUSHIKI KAISHA
135, Komakado 1-chome
Gotenba-shi, Shizuoka 4120038 / JP
04 / SEKIMORI, Yasuo, CHUGAI SEIYAKU KABUSHIKI KAISHA
135, Komakado 1-chome
Gotenba-shi, Shizuoka 4120038 / JP
05 / TSUCHIYA, Masayuki, CHUGAI SEIYAKU K. K.
135, Komakado 1-chome
Gotenba-shi, Shizuoka 4120038 / JP
 [2007/25]
Former [2006/18]01 / IRIE, Reiko
17624, Tramonto Drive
Pacific Palisades, California 90272 / US
02 / TSUNODA, Hiroyuki, CHUGAI SEIYAKU KABUSHIKI KAISHA
153-2, Nagai, Niihari-mura, Niihari-gun
Ibaraki 3004101 / JP
03 / IGAWA, Tomoyuki, CHUGAI SEIYAKU KABUSHIKI KAISHA
135, Komakado 1-chome
Gotenba-shi, Shizuoka 4120038 / JP
04 / SEKIMORI, Yasuo, CHUGAI SEIYAKU KABUSHIKI KAISHA
135, Komakado 1-chome
Gotenba-shi, Shizuoka 4120038 / JP
05 / TSUCHIYA, Masayuki, CHUGAI SEIYAKU K. K.
135, Komakado 1-chome
Gotenba-shi, Shizuoka 4120038 / JP
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2006/18]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date04747833.415.07.2004
[2006/18]
WO2004JP10444
Priority number, dateUS20030487333P15.07.2003         Original published format: US 487333 P
[2006/18]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2005005636
Date:20.01.2005
Language:EN
[2005/03]
Type: A1 Application with search report 
No.:EP1652925
Date:03.05.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 20.01.2005 takes the place of the publication of the European patent application.
[2006/18]
Type: B1 Patent specification 
No.:EP1652925
Date:08.12.2010
Language:EN
[2010/49]
Search report(s)International search report - published on:JP20.01.2005
(Supplementary) European search report - dispatched on:EP01.06.2007
ClassificationIPC:A61K39/395, C07K16/00, C07K16/30, C12N15/13, C12N5/10, G01N33/53, C07K16/18, C12P21/02, G01N27/447, G01N33/561
[2007/26]
CPC:
C07K16/3084 (EP,US); C07K16/00 (EP,US); G01N33/6854 (EP,US);
G01N33/686 (EP,US); C07K2317/21 (EP,US); C07K2317/52 (EP,US);
C07K2317/734 (EP,US) (-)
Former IPC [2006/18]C12N15/13, C12N5/10, C12P21/02, C07K16/18, A61K39/395, G01N33/561, G01N33/53, G01N27/447
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/18]
Extension statesALNot yet paid
HRNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:PRODUKTION VON IGM DURCH TRANSFORMIERTE ZELLEN UND VERFAHREN ZUR QUANTIFIZIERUNG DIESER IGM-PRODUKTION[2006/18]
English:IgM PRODUCTION BY TRANSFORMED CELLS AND METHODS FOR QUANTIFYING SAID IgM PRODUCTION[2006/18]
French:PRODUCTION D'IGM PAR CELLULES TRANSFORMEES ET PROCEDES DE QUANTIFICATION DE CETTE DERNIERE[2006/18]
Entry into regional phase15.02.2006Translation filed 
15.02.2006National basic fee paid 
15.02.2006Search fee paid 
15.02.2006Designation fee(s) paid 
15.02.2006Examination fee paid 
Examination procedure15.07.2004Request for preliminary examination filed
International Preliminary Examining Authority: JP
15.02.2006Amendment by applicant (claims and/or description)
15.02.2006Examination requested  [2006/18]
03.09.2007Despatch of a communication from the examining division (Time limit: M04)
18.12.2007Reply to a communication from the examining division
18.01.2008Despatch of a communication from the examining division (Time limit: M06)
23.07.2008Reply to a communication from the examining division
15.10.2008Despatch of a communication from the examining division (Time limit: M06)
27.04.2009Reply to a communication from the examining division
19.01.2010Date of oral proceedings
09.03.2010Minutes of oral proceedings despatched
28.04.2010Communication of intention to grant the patent
07.09.2010Fee for grant paid
07.09.2010Fee for publishing/printing paid
Divisional application(s)EP10150954.5  / EP2204190
Opposition(s)09.09.2011No opposition filed within time limit [2011/46]
Fees paidRenewal fee
15.02.2006Renewal fee patent year 03
31.07.2007Renewal fee patent year 04
31.07.2008Renewal fee patent year 05
20.07.2009Renewal fee patent year 06
27.07.2010Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
DK08.12.2010
EE08.12.2010
FI08.12.2010
HU08.12.2010
IT08.12.2010
NL08.12.2010
PL08.12.2010
RO08.12.2010
SE08.12.2010
SI08.12.2010
SK08.12.2010
TR08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
IE15.07.2011
LU15.07.2011
CH31.07.2011
LI31.07.2011
MC31.07.2011
[2013/45]
Former [2013/44]AT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
DK08.12.2010
EE08.12.2010
FI08.12.2010
IT08.12.2010
NL08.12.2010
PL08.12.2010
RO08.12.2010
SE08.12.2010
SI08.12.2010
SK08.12.2010
TR08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
IE15.07.2011
LU15.07.2011
CH31.07.2011
LI31.07.2011
MC31.07.2011
Former [2013/25]AT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
DK08.12.2010
EE08.12.2010
FI08.12.2010
IT08.12.2010
NL08.12.2010
PL08.12.2010
RO08.12.2010
SE08.12.2010
SI08.12.2010
SK08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
IE15.07.2011
LU15.07.2011
CH31.07.2011
LI31.07.2011
MC31.07.2011
Former [2012/35]AT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
DK08.12.2010
EE08.12.2010
FI08.12.2010
IT08.12.2010
NL08.12.2010
PL08.12.2010
RO08.12.2010
SE08.12.2010
SI08.12.2010
SK08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
IE15.07.2011
CH31.07.2011
LI31.07.2011
MC31.07.2011
Former [2012/20]AT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
DK08.12.2010
EE08.12.2010
FI08.12.2010
IT08.12.2010
NL08.12.2010
PL08.12.2010
RO08.12.2010
SE08.12.2010
SI08.12.2010
SK08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
CH31.07.2011
LI31.07.2011
MC31.07.2011
Former [2012/11]AT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
DK08.12.2010
EE08.12.2010
FI08.12.2010
IT08.12.2010
NL08.12.2010
PL08.12.2010
RO08.12.2010
SE08.12.2010
SI08.12.2010
SK08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
MC31.07.2011
Former [2012/03]AT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
DK08.12.2010
EE08.12.2010
FI08.12.2010
IT08.12.2010
NL08.12.2010
PL08.12.2010
RO08.12.2010
SE08.12.2010
SI08.12.2010
SK08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
Former [2011/47]AT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
DK08.12.2010
EE08.12.2010
FI08.12.2010
NL08.12.2010
PL08.12.2010
RO08.12.2010
SE08.12.2010
SI08.12.2010
SK08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
Former [2011/37]AT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
EE08.12.2010
FI08.12.2010
NL08.12.2010
PL08.12.2010
RO08.12.2010
SE08.12.2010
SI08.12.2010
SK08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
Former [2011/36]AT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
EE08.12.2010
FI08.12.2010
NL08.12.2010
PL08.12.2010
SE08.12.2010
SI08.12.2010
SK08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
Former [2011/35]AT08.12.2010
BE08.12.2010
CY08.12.2010
CZ08.12.2010
EE08.12.2010
FI08.12.2010
NL08.12.2010
SE08.12.2010
SI08.12.2010
BG08.03.2011
GR09.03.2011
ES19.03.2011
PT08.04.2011
Former [2011/32]AT08.12.2010
BE08.12.2010
CY08.12.2010
FI08.12.2010
NL08.12.2010
SE08.12.2010
SI08.12.2010
BG08.03.2011
ES19.03.2011
Former [2011/24]CY08.12.2010
FI08.12.2010
NL08.12.2010
SE08.12.2010
Documents cited:Search[X]EP0492409  (ISIHARA SANGYO KAISHA LTD [JP]) [X] 22-28 * the whole document *;
 [A]US2002119530  (MAIORELLA BRIAN [US], et al) [A] 1-37 * tables 1,2 *;
 [DXY]  - WOOD ET AL, "High level synthesis of immunoglobulins in chinese hamster ovary cells", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, (199011), vol. 145, no. 9, ISSN 0022-1767, pages 3011 - 3016, XP002112010 [DX] 1-6 * the whole document * [Y] 11-21,29-37
 [XA]  - HUGHEY C T ET AL, "Production of IgM hexamers by normal and autoimmune B cells: implications for the physiologic role of hexameric IgM.", JOURNAL OF IMMUNOLOGY (BALTIMORE, MD. : 1950) 15 OCT 1998, (19981015), vol. 161, no. 8, ISSN 0022-1767, pages 4091 - 4097, XP002430236 [X] 38-41 * the whole document * [A] 1-37
 [XY]  - HUANG T J ET AL, "Production of recombinant murine-human chimeric IgM and IgG anti-Js(b) for use in the clinical laboratory.", TRANSFUSION JUN 2003, (200306), vol. 43, no. 6, ISSN 0041-1132, pages 758 - 764, XP008077998 [X] 7 * the whole document * [Y] 8-10

DOI:   http://dx.doi.org/10.1046/j.1537-2995.2003.00393.x
 [X]  - SHITARA K ET AL, "Immunoglobulin class switch of anti- ganglioside monoclonal antibody from IgM to IgG", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, (1994), vol. 169, no. 1, ISSN 0022-1759, pages 83 - 92, XP002101158 [X] 22-28 * the whole document *

DOI:   http://dx.doi.org/10.1016/0022-1759(94)90127-9
 [XY]  - SORENSEN VIGDIS ET AL, "Structural requirements for incorporation of J chain into human IgM and IgA", INTERNATIONAL IMMUNOLOGY, (200001), vol. 12, no. 1, ISSN 0953-8178, pages 19 - 27, XP002430237 [X] 38-41 [Y] 8-21,29-37

DOI:   http://dx.doi.org/10.1093/intimm/12.1.19
 [Y]  - RANDALL T D ET AL, "Direct evidence that J chain regulates the polymeric structure of IgM in antibody-secreting B cells.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 5 SEP 1992, (19920905), vol. 267, no. 25, ISSN 0021-9258, pages 18002 - 18007, XP002430238 [Y] 8-21,29-37 * page 1803, column 2, paragraphs 2,3 * * figure 6B *
 [A]  - BREWER J W ET AL, "Mechanism and subcellular localization of secretory IgM polymer assembly.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 24 JUN 1994, (19940624), vol. 269, no. 25, ISSN 0021-9258, pages 17338 - 17348, XP002430239 [A] 38-41 * page 17339, column 2, paragraphs 5,6 * * page 17340; figure 1 *
International search[Y]  - TACHIBANA T., "Gene expression of joining chain in murine peritoneal B-1 cells", NIHON UNIV. DENT. J., (2002), vol. 76, no. 5, pages 425 - 433, XP002982264
 [Y]  - STOLL T.S. ET AL, "Effects of culture conditions on the production and quality of monoclonal IgA", ENZYME AND MICROBIAL TECHNOLOGY, (19970815), vol. 21, no. 3, pages 203 - 211, XP002982265

DOI:   http://dx.doi.org/10.1016/S0141-0229(96)00268-2
 [A]  - MAYUS J.L. ET AL, "Inhibition of in vitro anti-DNA B-cell responses by cyclosporine", CELL. IMMUNOL., (1985), vol. 94, no. 1, pages 195 - 204, XP002982266

DOI:   http://dx.doi.org/10.1016/0008-8749(85)90096-6
 [A]  - STOCKS S.J. ET AL, "Production and isolation of large quantities of monoclonal antibody using serum-free medium and fast protein liquid chromatography", HYBRIDOMA, (1989), vol. 8, no. 2, pages 241 - 247, XP002982267
ExaminationWO03046162
    - HOON ET AL, "Molecular cloning of a human monoclonal antibody reactive to ganglioside GM3 antigen on human cancers", CANCER RESEARCH, (19931101), vol. 53, no. 21, pages 5244 - 5250, XP002017118
    - YOUD M.E. ET AL, "Synergistic roles of IgM and complement in antigen trapping and follicular localization", EUROPEAN JOURNAL OF IMMUNOLOGY, (200208), vol. 32, no. 8, pages 2328 - 2337
    - REIKO I.F. ET AL, "Phase I pilot clinical trial of human IgM monoclonal antibody to ganglioside GM3 in patients with metastatic melanoma", CANCER IMMUNOLOGY IMMUNOTHERAPY, (200402), vol. 53, no. 2, pages 110 - 117
by applicantWO8901975
 US5057313
 US5156840
 WO9219759
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.