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Extract from the Register of European Patents

EP About this file: EP1620422

EP1620422 - PHENYL SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  02.04.2010
Database last updated on 18.11.2024
Most recent event   Tooltip02.04.2010Application deemed to be withdrawnpublished on 05.05.2010  [2010/18]
Applicant(s)For all designated states
The Institutes for Pharmaceutical Discovery, LLC
23 Business Park Drive
Branford, CT 06405 / US
[2006/05]
Inventor(s)01 / WHITEHOUSE, Darren
40 Fishing Brook Road
Westbrook, CT 06498 / US
02 / HU, Shaojing
900 Mix Avenue, Unit 121
Hamden, CT 06514 / US
03 / FANG, Haiquan
304 County Road
Madison, CT 06443 / US
04 / VAN ZANDT, Michael
91 Golden Hill Drive
Guilford, CT 06437 / US
 [2006/05]
Representative(s)Adam, Holger
Kraus & Weisert
Patentanwälte PartGmbB
Thomas-Wimmer-Ring 15
80539 München / DE
[N/P]
Former [2006/05]Adam, Holger
Kraus & Weisert, Patent- und Rechtsanwälte, Thomas-Wimmer-Ring 15
80539 München / DE
Application number, filing date04751193.630.04.2004
[2006/05]
WO2004US13701
Priority number, dateUS20030466868P30.04.2003         Original published format: US 466868 P
[2006/05]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2004099170
Date:18.11.2004
Language:EN
[2004/47]
Type: A2 Application without search report 
No.:EP1620422
Date:01.02.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 18.11.2004 takes the place of the publication of the European patent application.
[2006/05]
Search report(s)International search report - published on:EP15.09.2005
ClassificationIPC:C07D307/91
[2006/05]
CPC:
C07D307/79 (EP,KR,US); A61P25/00 (EP); A61P3/00 (EP);
A61P3/04 (EP); A61P3/10 (EP); A61P35/00 (EP);
A61P37/02 (EP); A61P43/00 (EP); A61P9/00 (EP);
C07C311/19 (EP,US); C07C311/29 (EP,US); C07D209/08 (EP,US);
C07D307/80 (EP,KR,US); C07D307/81 (EP,US); C07D307/91 (EP,KR,US);
C07D401/04 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/05]
Extension statesAL02.11.2005
HR02.11.2005
LT02.11.2005
LV02.11.2005
MK02.11.2005
TitleGerman:PHENYL SUBSTITUIERTE CARBONSÄUREN ALS HEMMER DER PROTEIN-TYROSINPHOSPHATASE-1B[2006/05]
English:PHENYL SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B[2006/05]
French:ACIDES CARBOXYLIQUES SUBSTITUES PAR PHENYLE COMME INHIBITEURS DE PROTEINE TYROSINE-PHOSPHATASE-1B[2006/05]
Entry into regional phase02.11.2005National basic fee paid 
02.11.2005Designation fee(s) paid 
02.11.2005Examination fee paid 
Examination procedure02.11.2005Examination requested  [2006/05]
16.01.2008Despatch of a communication from the examining division (Time limit: M06)
18.07.2008Reply to a communication from the examining division
03.11.2009Application deemed to be withdrawn, date of legal effect  [2010/18]
07.12.2009Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2010/18]
Fees paidRenewal fee
26.04.2006Renewal fee patent year 03
27.04.2007Renewal fee patent year 04
25.04.2008Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
30.04.200906   M06   Not yet paid
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Cited inInternational search[X]JPS59141540  (CHISSO CORP) [X] 1-4,6-8,10-17,41-45 * Compounds 3 and 4 and the precursors thereof *;
 [X]EP0561639  (LILLY CO ELI [US]) [X] 1-4,6-8,10-17,41-45 * page 26; table 16 * * page 28; table 17 *;
 [X]EP0744407  (LILLY CO ELI [US]) [X] 1-4,6-8,10-17,41-45 * Page 12, Preparation 3; Page 16, Preparation 12 *;
 [X]WO0050375  (CLARIANT GMBH [DE], et al) [X] 1-4,6-8,10-17,41-45 * examples 5,13; claim 1 *;
 [PX]JP2003238551  (FUJI PHOTO FILM CO LTD) [PX] 1-57* the whole document *;
 [X]  - MALAMAS M S ET AL, "Novel Benzofuran and Benzothiophene Biphenyls as Inhibitors of Protein Tyrosine Phosphatase 1B with Antihyperglycemic Properties", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (2000), vol. 43, ISSN 0022-2623, pages 1293 - 1310, XP002216395 [X] 1-57 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm990560c
 [X]  - SADASHIVA, B. K. ET AL, "A convenient method for the preparation of 4-n-alkyl-4''-cyano-p-terphenyl", CAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1977:502050, URL: STN, XP002301745 [X] 1-4,6-8,10-17,41-45 * compounds 63809-04-1, 63809-05-2 *
 [X]  - DEBONO M. ET AL., "Semisynthetic Chemical Modification of the Antifungal Lipopeptide Echinocandin B (ECB): Structure-Activity Studies of the Lipophilic and Geometric Parameters of Polyarylated Acyl Analogs of ECB", JOURNAL OF MEDICINAL CHEMISTRY, (1995), vol. 38, no. 17, pages 3271 - 3281, XP000608473 [X] 1-4,6-8,10-17,41-45 * page 3279; compounds 14AA,14BB *

DOI:   http://dx.doi.org/10.1021/jm00017a012
 [X]  - HIMMEL, HANS-JOERG ET AL, "Fabrication of a Carboxyl-Terminated Organic Surface with Self-Assembly of Functionalized Terphenylthiols: The Importance of Hydrogen Bond Formation", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (1998), vol. 120, no. 46, pages 12069 - 12074, XP002301744 [X] 1-4,6-8,10-17,41-45 * Page 12070, two intermediates in the preparation of 4'Carboxyterphenyl-4-methanethiol *

DOI:   http://dx.doi.org/10.1021/ja981872s
 [X]  - CONN M. M. ET AL., "Template Effects in New Self-Replicating Molecules", ANGEW. CHEM. INT. ED. ENGL., (1994), vol. 33, pages 1577 - 1579, XP002301796 [X] 1,7 * compounds 3,5 *

DOI:   http://dx.doi.org/10.1002/anie.199415771
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.