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Extract from the Register of European Patents

EP About this file: EP1625149

EP1625149 - METHOD AND CARRIER COMPLEXES FOR DELIVERING MOLECULES TO CELLS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.12.2016
Database last updated on 25.09.2024
Most recent event   Tooltip13.07.2018Lapse of the patent in a contracting state
New state(s): TR		published on 15.08.2018  [2018/33]
Applicant(s)For all designated states
Cornell Research Foundation, Inc.
395 Pine Tree Road, Suite 310
Ithaca, NY 14850 / US
[2016/07]
Former [2014/25]For all designated states
Cornell Research Foundation, Inc.
395 Pine Tree Road, Suite 310
Ithaca NY 14850 / US
Former [2006/07]For all designated states
CORNELL RESEARCH FOUNDATION, INC.
20 Thornwood Drive, Suite 105
Ithaca, NY 14850 / US
Inventor(s)01 / SZETO, Hazel
50 East 89th Street
Apartment 25A
New York, NY 10128 / US
02 / ZHAO, Kesheng
33-04 93rd Street
Apartment 4X
Jackson Heights, NY 11372 / US
03 / BIRK, Alex, V.
8305 98th Street
Apartment 5S
Woodhaven, NY 11421 / US
04 / ROBERTSON, Hugh, D.
430 East 63rd Street, 2J
New York, NY 10021 / US
 [2016/07]
Former [2006/07]01 / SZETO, Hazel
50 East 89th Street, Apartment 25A
New York, NY 10128 / US
02 / ZHAO, Kesheng
33-04 93rd Street, Apartment 4X
Jackson Heights, NY 11372 / US
03 / BIRK, Alex, V.
8305 98th Street, Apartment 5S
Woodhaven, NY 11421 / US
04 / ROBERTSON, Hugh, D.
430 East 63rd Street, 2J
New York, NY 10021 / US
Representative(s)Duckworth, Timothy John, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[2013/11]
Former [2010/41]Thurgood, Alexander John, et al
IP Galore 4, rue Durette
F-63500 Brenat / FR
Former [2006/07]Thurgood, Alexander John, et al
Cabinet Richebourg "Le Clos du Golf" 69, rue Saint-Simon
42000 Saint-Etienne / FR
Application number, filing date04751253.803.05.2004
[2006/07]
WO2004US13772
Priority number, dateUS20030467516P01.05.2003         Original published format: US 467516 P
[2006/07]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2005001023
Date:06.01.2005
Language:EN
[2005/01]
Type: A2 Application without search report 
No.:EP1625149
Date:15.02.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 06.01.2005 takes the place of the publication of the European patent application.
[2006/07]
Type: B1 Patent specification 
No.:EP1625149
Date:17.02.2016
Language:EN
[2016/07]
Search report(s)International search report - published on:US28.04.2005
(Supplementary) European search report - dispatched on:EP03.09.2010
ClassificationIPC:C07K5/00, A61K47/48, A61P31/00, A61P39/06, A61P35/00, C07K5/11, C07K5/107, C07K5/08
[2015/34]
CPC:
A61K31/713 (EP,US); C07K5/00 (KR); C07K17/00 (US);
A61K38/47 (EP,US); A61K47/64 (EP,US); A61K47/645 (EP,US);
A61P1/00 (EP); A61P1/16 (EP); A61P13/12 (EP);
A61P25/00 (EP); A61P3/02 (EP); A61P31/00 (EP);
A61P31/04 (EP); A61P35/00 (EP); A61P39/00 (EP);
A61P39/06 (EP); A61P9/00 (EP); C07K5/08 (US);
C07K5/1016 (EP,US); C07K5/1019 (EP,US); C12N15/113 (US);
C12N15/87 (EP,US); C12N9/2471 (EP,US); C12N9/96 (EP,US);
C12Y302/01023 (EP,US); C12N2310/3513 (US); C12N2320/32 (US) (-)
Former IPC [2010/39]C07K5/00, A61K47/48, A61P31/00, A61P39/06, A61P35/00
Former IPC [2006/07]C07K5/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/07]
Former [2006/07]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IT,  LI,  LU,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:VERFAHREN UND TRÄGERKOMPLEXE ZUM TRANSPORT VON MOLEKÜLEN ZU ZELLEN[2006/07]
English:METHOD AND CARRIER COMPLEXES FOR DELIVERING MOLECULES TO CELLS[2006/07]
French:PROCEDE ET COMPLEXES PORTEURS PERMETTANT D'ADMINISTRER DES MOLECULES A DES CELLULES[2006/07]
Entry into regional phase01.12.2005National basic fee paid 
01.12.2005Search fee paid 
01.12.2005Designation fee(s) paid 
01.12.2005Examination fee paid 
Examination procedure01.12.2005Examination requested  [2006/07]
07.03.2011Despatch of a communication from the examining division (Time limit: M06)
17.09.2011Reply to a communication from the examining division
14.05.2013Despatch of a communication from the examining division (Time limit: M06)
10.10.2013Reply to a communication from the examining division
08.10.2014Despatch of a communication from the examining division (Time limit: M06)
14.04.2015Reply to a communication from the examining division
29.07.2015Communication of intention to grant the patent
26.11.2015Fee for grant paid
26.11.2015Fee for publishing/printing paid
10.12.2015Information about intention to grant a patent
10.12.2015Receipt of the translation of the claim(s)
Divisional application(s)EP13159232.1  / EP2604621
EP13159235.4  / EP2604285
EP13159237.0  / EP2604286
EP13159248.7  / EP2604287
EP16188609.8  / EP3167935
EP18162652.4  / EP3381515
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  07.03.2011
Opposition(s)18.11.2016No opposition filed within time limit [2017/04]
Fees paidRenewal fee
30.05.2006Renewal fee patent year 03
30.05.2007Renewal fee patent year 04
28.05.2008Renewal fee patent year 05
27.05.2009Renewal fee patent year 06
25.05.2010Renewal fee patent year 07
25.05.2011Renewal fee patent year 08
25.05.2012Renewal fee patent year 09
28.05.2013Renewal fee patent year 10
04.03.2014Renewal fee patent year 11
27.05.2015Renewal fee patent year 12
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU03.05.2004
AT17.02.2016
BE17.02.2016
CY17.02.2016
CZ17.02.2016
EE17.02.2016
ES17.02.2016
MC17.02.2016
PL17.02.2016
RO17.02.2016
SI17.02.2016
SK17.02.2016
TR17.02.2016
BG17.05.2016
GR18.05.2016
PT17.06.2016
[2018/29]
Former [2018/28]HU03.05.2004
AT17.02.2016
BE17.02.2016
CY17.02.2016
CZ17.02.2016
EE17.02.2016
ES17.02.2016
MC17.02.2016
PL17.02.2016
RO17.02.2016
SI17.02.2016
SK17.02.2016
BG17.05.2016
GR18.05.2016
PT17.06.2016
Former [2017/13]AT17.02.2016
BE17.02.2016
CZ17.02.2016
EE17.02.2016
ES17.02.2016
PL17.02.2016
RO17.02.2016
SI17.02.2016
SK17.02.2016
BG17.05.2016
GR18.05.2016
PT17.06.2016
Former [2017/03]AT17.02.2016
BE17.02.2016
CZ17.02.2016
EE17.02.2016
ES17.02.2016
PL17.02.2016
RO17.02.2016
SK17.02.2016
GR18.05.2016
PT17.06.2016
Former [2016/50]AT17.02.2016
CZ17.02.2016
EE17.02.2016
ES17.02.2016
PL17.02.2016
RO17.02.2016
SK17.02.2016
GR18.05.2016
BE31.05.2016
PT17.06.2016
Former [2016/49]AT17.02.2016
EE17.02.2016
ES17.02.2016
PL17.02.2016
GR18.05.2016
BE31.05.2016
PT17.06.2016
Former [2016/38]AT17.02.2016
ES17.02.2016
PL17.02.2016
GR18.05.2016
BE31.05.2016
PT17.06.2016
Former [2016/36]AT17.02.2016
ES17.02.2016
PL17.02.2016
GR18.05.2016
BE31.05.2016
Former [2016/35]ES17.02.2016
GR18.05.2016
Documents cited:Search[A]WO9118012  (BIOSPAN CORP [US]) [A] 1-123 * example 1; claim 1 *;
 [A]WO0166147  (ALPHARMA AS [NO], et al) [A] 1-123* claim 1; table 8 *;
 [X]WO0236612  (UNIV CAMBRIDGE TECH [GB], et al) [X] 1-4,7,8,10,11,20-22,30,32,51,63-69,72,73,75,76,85,86,88,89,97,98,118-123 * page 11, line 16 - page 12, line 25; claim 2; table 1; sequence 26 * * page 21, line 7 - page 22, line 9 *;
 [A]WO02069930  (CELLGATE INC [US]) [A] 57 * claim 30 *;
 [A]WO02089776  (LOHMANN THERAPIE SYST LTS [DE], et al) [A] 59 * claims 1, 5 *;
 [X]  - VAARA M ET AL, "Group of Peptides That Act Synergistically with Hydrophobic Antibiotics against Gram-Negative Enteric Bacteria", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, DC, US, (19960801), vol. 40, no. 8, ISSN 0066-4804, pages 1801 - 1805, XP002998512 [X] 1,2,4,5,7,11,12,20-22,30,32,51,66,67,69,70,72,76,77,85,86,88,89,97,98,121 * figure 2a; tables 1, 2 * * paragraph bridging page 1804 - page 1805 *
 [X]  - JANAKY T ET AL, "Short-chain analogs of luteinizing hormone-releasing hormone containing cytotoxic moieties", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES (PNAS), NATIONAL ACADEMY OF SCIENCE, US LNKD- DOI:10.1073/PNAS.89.21.10203, (19920101), vol. 89, no. 21, ISSN 0027-8424, pages 10203 - 10207, XP002521405 [X] 1-3,7,8,10-13,20-22,24,25,30,32,53,54,62-68,72,73,75-78,85,86,88,89,91,92,97,98,117-123 * compound Ac-Ser-Tyr-D-Lys(glutaryl-DOX)-Leu-Arg-Pro-NH-Et; page 10204, column 1 * * page 10206, column 1, line 35 - line 39 *

DOI:   http://dx.doi.org/10.1073/pnas.89.21.10203
 [X]  - T.JANÁKY, A. JUHÁSZ, S. BAJUSZ ET AL., "Analogues of luteinizing hormone-releasing hormone containing cytotoxic groups", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, (199202), vol. 89, pages 972 - 976, XP002597190 [X] 1-3,7-11,20-22,24,25,30,32,53,54,62-68,72-76,85,86,88,89,91,92,97,98,117-123 * tables 1, 3; compound VII *

DOI:   http://dx.doi.org/10.1073/pnas.89.3.972
International search[A]US6221355  (DOWDY STEVEN F [US]);
 [AP]  - DRIN, ET AL., "Studies on the Internalization Mechanism of Cationic Cell-penetrating Peptides", JOURNAL OF BIOLOGICAL CHEMISTRY, (20030815), vol. 278, no. 33, pages 31192 - 31201, XP002983988

DOI:   http://dx.doi.org/10.1074/jbc.M303938200
 [A]  - RICHARD ET AL., "Cell-penetrating Peptides", JOURNAL OF BIOLOGICAL CHEMISTRY, (200301), vol. 278, no. 1, pages 585 - 590, XP002983989

DOI:   http://dx.doi.org/10.1074/jbc.M209548200
ExaminationEP2491943
    - ZHAO K ET AL, "TRANSCELLULAR TRANSPORT OF A HIGHLY POLAR 3+ NET CHARGE OPIOID TETRAPEPTIDE", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMERICAN SOCIETY FOR PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, US, (20030101), vol. 304, no. 1, doi:10.1124/JPET.102.040147, ISSN 0022-3565, pages 425 - 432, XP002542455

DOI:   http://dx.doi.org/10.1124/jpet.102.040147
by applicant   - RICHARD ET AL., JBIOL. CHEM., (2003), vol. 278, pages 585 - 590
    - DRIN ET AL., JBIOL. CHEM., (2003), vol. 278, pages 31192 - 31201
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.