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Extract from the Register of European Patents

EP About this file: EP1635825

EP1635825 - SYNERGISTIC COMBINATIONS INCLUDING N-ACYLATED 4-HYDROXYPHENYLAMINE DERIVATIVES AND CAFFEINE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.08.2009
Database last updated on 03.10.2024
Most recent event   Tooltip30.09.2011Lapse of the patent in a contracting state
New state(s): CY, TR
published on 02.11.2011  [2011/44]
Applicant(s)For all designated states
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
3810 Lakeshore Drive System Building, Suite 115
Baton Rouge, Louisiana 70808 / US
[2008/33]
Former [2006/12]For all designated states
The Foundation for the LSU Health Sciences Center
2000 Tulane Avenue
New Orleans, LA 70112 / US
Inventor(s)01 / BAZAN, Nicolas, G.
478 Broadway Street
New Orleans, LA 70118 / US
02 / SUNKEL, Carlos
Calle Amara 47
E-28033 Madrid / ES
03 / BUILLA, Julio, Alvarez
C. Condado de Treoino a
E-28033 Madrid / ES
04 / PAUL, Dennis
836 Louisiana Avenue
New Orleans, LA 70115 / US
 [2006/12]
Representative(s)Gregory, Robert John H.
WP Thompson
8th Floor
1 Mann Island
Liverpool L3 1BP / GB
[N/P]
Former [2008/02]Gregory, Robert John H.
W.P. Thompson & Co. Coopers Building Church Street Liverpool
L1 3AB / GB
Former [2007/34](deleted)
Former [2006/12]HOEIBERG A/S
European Patent & Trademark Attorneys Store Kongensgade 59A
1264 Copenhagen K / DK
Application number, filing date04754946.410.06.2004
[2006/12]
WO2004US18514
Priority number, dateUS2003045991112.06.2003         Original published format: US 459911
[2006/12]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2004110440
Date:23.12.2004
Language:EN
[2004/52]
Type: A1 Application with search report 
No.:EP1635825
Date:22.03.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 23.12.2004 takes the place of the publication of the European patent application.
[2006/12]
Type: B1 Patent specification 
No.:EP1635825
Date:01.10.2008
Language:EN
[2008/40]
Search report(s)International search report - published on:EP23.12.2004
ClassificationIPC:A61K31/428, A61K31/485, A61P25/04, A61K31/522
[2006/12]
CPC:
A61K31/428 (EP,US); A61K31/425 (EP,US); A61K31/485 (EP,US);
A61K31/522 (EP,US); A61P25/04 (EP)
C-Set:
A61K31/425, A61K2300/00 (EP,US);
A61K31/428, A61K2300/00 (US,EP);
A61K31/485, A61K2300/00 (US,EP);
A61K31/522, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/12]
Extension statesALNot yet paid
HRNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
TitleGerman:SYNERGISTISCHE KOMBINATIONEN ENTHALTEND N-ACYLIERTE 4-HYDROXYPHENYLAMIN DERIVATE UND KOFFEIN[2006/12]
English:SYNERGISTIC COMBINATIONS INCLUDING N-ACYLATED 4-HYDROXYPHENYLAMINE DERIVATIVES AND CAFFEINE[2006/12]
French:COMBINAISONS SYNERGIQUES CONTENANT DES DERIVES DE 4- HYDROXYPHENYLAMINES N-ACYLEES ET DE LA CAFEINE[2008/15]
Former [2006/12]COMBINAISONS SYNERGIQUES CONTENANT DES DERIVES DE 4- HYDROXYPHENYLAMINES N-ACYLEES ET CAFEINE
Entry into regional phase12.01.2006National basic fee paid 
12.01.2006Designation fee(s) paid 
12.01.2006Examination fee paid 
Examination procedure12.01.2006Examination requested  [2006/12]
08.03.2006Amendment by applicant (claims and/or description)
14.03.2006Despatch of a communication from the examining division (Time limit: M04)
06.04.2006Reply to a communication from the examining division
18.04.2006Despatch of a communication from the examining division (Time limit: M06)
26.10.2006Reply to a communication from the examining division
14.04.2008Communication of intention to grant the patent
08.08.2008Fee for grant paid
08.08.2008Fee for publishing/printing paid
Opposition(s)02.07.2009No opposition filed within time limit [2009/37]
Fees paidRenewal fee
30.06.2006Renewal fee patent year 03
21.11.2007Renewal fee patent year 04
14.07.2008Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
30.06.200704   M06   Fee paid on   21.11.2007
30.06.200805   M06   Fee paid on   14.07.2008
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT01.10.2008
BE01.10.2008
CY01.10.2008
CZ01.10.2008
DK01.10.2008
EE01.10.2008
FI01.10.2008
PL01.10.2008
RO01.10.2008
SI01.10.2008
SK01.10.2008
TR01.10.2008
BG01.01.2009
SE01.01.2009
GR02.01.2009
PT02.03.2009
HU02.04.2009
IE10.06.2009
LU10.06.2009
CH30.06.2009
LI30.06.2009
MC30.06.2009
[2011/43]
Former [2011/32]AT01.10.2008
BE01.10.2008
CZ01.10.2008
DK01.10.2008
EE01.10.2008
FI01.10.2008
PL01.10.2008
RO01.10.2008
SI01.10.2008
SK01.10.2008
BG01.01.2009
SE01.01.2009
GR02.01.2009
PT02.03.2009
HU02.04.2009
IE10.06.2009
LU10.06.2009
CH30.06.2009
LI30.06.2009
MC30.06.2009
Former [2011/21]AT01.10.2008
BE01.10.2008
CZ01.10.2008
DK01.10.2008
EE01.10.2008
FI01.10.2008
PL01.10.2008
RO01.10.2008
SI01.10.2008
SK01.10.2008
BG01.01.2009
SE01.01.2009
GR02.01.2009
PT02.03.2009
IE10.06.2009
LU10.06.2009
CH30.06.2009
LI30.06.2009
MC30.06.2009
Former [2010/50]AT01.10.2008
BE01.10.2008
CZ01.10.2008
DK01.10.2008
EE01.10.2008
FI01.10.2008
PL01.10.2008
RO01.10.2008
SI01.10.2008
SK01.10.2008
BG01.01.2009
SE01.01.2009
GR02.01.2009
PT02.03.2009
IE10.06.2009
CH30.06.2009
LI30.06.2009
MC30.06.2009
Former [2010/21]AT01.10.2008
BE01.10.2008
CZ01.10.2008
DK01.10.2008
EE01.10.2008
FI01.10.2008
PL01.10.2008
RO01.10.2008
SI01.10.2008
SK01.10.2008
BG01.01.2009
SE01.01.2009
PT02.03.2009
IE10.06.2009
CH30.06.2009
LI30.06.2009
MC30.06.2009
Former [2010/07]AT01.10.2008
BE01.10.2008
CZ01.10.2008
DK01.10.2008
EE01.10.2008
FI01.10.2008
PL01.10.2008
RO01.10.2008
SI01.10.2008
SK01.10.2008
BG01.01.2009
SE01.01.2009
PT02.03.2009
MC30.06.2009
Former [2009/44]AT01.10.2008
BE01.10.2008
CZ01.10.2008
DK01.10.2008
EE01.10.2008
FI01.10.2008
PL01.10.2008
RO01.10.2008
SI01.10.2008
SK01.10.2008
BG01.01.2009
SE01.01.2009
PT02.03.2009
Former [2009/41]AT01.10.2008
BE01.10.2008
CZ01.10.2008
DK01.10.2008
EE01.10.2008
FI01.10.2008
PL01.10.2008
RO01.10.2008
SI01.10.2008
BG01.01.2009
SE01.01.2009
PT02.03.2009
Former [2009/36]AT01.10.2008
BE01.10.2008
DK01.10.2008
EE01.10.2008
FI01.10.2008
PL01.10.2008
RO01.10.2008
SI01.10.2008
BG01.01.2009
PT02.03.2009
Former [2009/35]AT01.10.2008
BE01.10.2008
DK01.10.2008
FI01.10.2008
PL01.10.2008
SI01.10.2008
BG01.01.2009
PT02.03.2009
Former [2009/32]AT01.10.2008
BE01.10.2008
FI01.10.2008
PL01.10.2008
SI01.10.2008
BG01.01.2009
PT02.03.2009
Former [2009/26]AT01.10.2008
FI01.10.2008
PL01.10.2008
SI01.10.2008
BG01.01.2009
PT02.03.2009
Former [2009/24]AT01.10.2008
FI01.10.2008
SI01.10.2008
BG01.01.2009
Former [2009/17]SI01.10.2008
Cited inInternational search[YD]WO9632940  (LSU MEDICAL CENTER FOUNDATION [US]) [YD] 1-48 * the whole document *;
 [PY]WO2004043460  (LSU MEDICAL CT FOUNDATION [US]) [PY] 1-48 * the whole document *;
 [Y]  - VIGNON E ET AL, Multicenter, double-blind, clinical trial comparing two tablets bid to one tablet qid of the same acetaminophen-dextropropoxyphen-caffeine combination in patients with osteoarthritis, SEMAINE DES HOPITAUX, VOL. 75, NR. 13-14, PAGE(S) 419-425, (19990415), ISSN 0037-1777, XP009037373 [Y] 1,14,15,25,38,39 * abstract *
 [Y]  - ENGELHARDT GUENTHER ET AL, "Role of caffeine in combined analgesic drugs from the point of view of experimental pharmacology", ARZNEIMITTEL-FORSCHUNG, (1997), vol. 47, no. 8, ISSN 0004-4172, pages 917 - 927, XP001183579 [Y] 16,40 * abstract * * page 926, column 2, paragraph 3 *
 [Y]  - TRUTER ILSE, "An investigation into compound analgesic prescribing in South Africa, with special emphasis on meprobamate-containing analgesics", PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, (199803), vol. 7, no. 2, ISSN 1053-8569, pages 91 - 97, XP009037383 [Y] 1-3,25-27 * abstract *

DOI:   http://dx.doi.org/10.1002/(SICI)1099-1557(199803/04)7:2<91::AID-PDS331>3.3.CO;2-B
 [Y]  - GOLDSTEIN JEROME, "Caffeine as an analgesic adjuvant", INFLAMMOPHARMACOLOGY, (2001), vol. 9, no. 1-2, ISSN 0925-4692, pages 51 - 61, XP009037382 [Y] 1-48 * abstract *

DOI:   http://dx.doi.org/10.1163/156856001300248326
 [YD]  - ZHANG W Y, "A benefit-risk assessment of caffeine as an analgesic adjuvant.", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (2001), Database accession no. NLM11772146, XP002298698 [YD] 1-48 * abstract *
    [ ] - DRUG SAFETY : AN INTERNATIONAL JOURNAL OF MEDICAL TOXICOLOGY AND DRUG EXPERIENCE. 2001, (2001), vol. 24, no. 15, ISSN 0114-5916, pages 1127 - 1142
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.