| EP1656132 - NOVEL PYRROLE-BASED HMG-COA REDUCTASE INHIBITORS [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 26.06.2009 Database last updated on 11.04.2026 | Most recent event Tooltip | 26.06.2009 | Application deemed to be withdrawn | published on 29.07.2009 [2009/31] | Applicant(s) | For all designated states Warner-Lambert Company LLC 235 East 42nd Street New York, NY 10017 / US | [2007/08] |
| Former [2006/20] | For all designated states Warner-Lambert Company LLC 201 Tabor Road Morris Plains New Jersey 07950 / US | Inventor(s) | 01 /
KENNEDY, Robert M., Pfizer Global Res.&Development 2800 Plymouth Road Ann Arbor, MI 48105 / US | 02 /
PARK, William K.-Ch., Pfizer Global Res.&Developm. 2800 Plymouth Road Ann Arbor, MI 48105 / US | 03 /
ROTH, Bruce David, Pfizer Global Res.&Development 2800 Plymouth Road Ann Arbor, MI 48105 / US | 04 /
SONG, Yuntao, Pfizer Global Res.&Development 2800 Plymouth Road Ann Arbor, MI 48105 / US | 05 /
TRIVEDI, Bharat K., Pfizer Global Res.&Development 2800 Plymouth Road Ann Arbor, MI 48105 / US | [2006/20] | Representative(s) | Hayles, James Richard Pfizer ATTENTION: ADDRESS INACTIVE - USE ASS-NR - CDR / FR | [N/P] |
| Former [2006/20] | Hayles, James Richard Pfizer Limited, Patents Department, Ramsgate Road Sandwich Kent CT13 9NJ / GB | Application number, filing date | 04769110.0 | 30.07.2004 | [2006/20] | WO2004IB02540 | Priority number, date | US20030494216P | 11.08.2003 Original published format: US 494216 P | [2006/20] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2005014539 | Date: | 17.02.2005 | Language: | EN | [2005/07] | Type: | A2 Application without search report | No.: | EP1656132 | Date: | 17.05.2006 | Language: | EN | The application published by WIPO in one of the EPO official languages on 17.02.2005 takes the place of the publication of the European patent application. | [2006/20] | Search report(s) | International search report - published on: | EP | 12.05.2005 | Classification | IPC: | A61K31/40, C07D207/34, A61P3/06, A61K31/4025, C07D401/04, C07D401/12, C07D207/32, C07D405/06, C07D319/06, C07C311/11 | [2006/20] | CPC: |
C04B35/632 (EP,US);
A61P13/08 (EP);
A61P19/10 (EP);
A61P25/28 (EP);
A61P3/06 (EP);
A61P43/00 (EP);
A61P9/10 (EP);
C07C303/40 (EP,US);
C07C311/13 (EP,US);
C07D207/33 (EP,US);
C07D207/34 (EP,US);
C07D207/36 (EP,US);
C07D319/06 (EP,US);
C07D401/04 (EP,US);
C07D401/12 (EP,US);
C07D403/12 (EP,US);
C07D405/06 (EP,US);
C07D405/12 (EP,US);
| C-Set: |
C07C303/40, C07C311/13 (EP,US)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2006/20] | Extension states | AL | Not yet paid | HR | Not yet paid | LT | Not yet paid | LV | Not yet paid | MK | Not yet paid | Title | German: | NEUE HMG-COA-REDUCTASE-HEMMER AUF PYRROLBASIS | [2006/20] | English: | NOVEL PYRROLE-BASED HMG-COA REDUCTASE INHIBITORS | [2006/20] | French: | INHIBITEURS NOUVEAUX DE L'HMG-COA REDUCTASE A BASE DE PYRROLE | [2006/20] | Entry into regional phase | 13.03.2006 | National basic fee paid | 13.03.2006 | Designation fee(s) paid | 13.03.2006 | Examination fee paid | Examination procedure | 17.09.2004 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 13.03.2006 | Examination requested [2006/20] | 01.12.2008 | Despatch of a communication from the examining division (Time limit: M04) | 02.02.2009 | Application deemed to be withdrawn, date of legal effect [2009/31] | 10.03.2009 | Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2009/31] | Fees paid | Renewal fee | 31.07.2006 | Renewal fee patent year 03 | 31.07.2007 | Renewal fee patent year 04 | Penalty fee | Additional fee for renewal fee | 31.07.2008 | 05   M06   Not yet paid |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [A] GRAUL A ET AL: "Atorvastatin Calcium", DRUGS OF THE FUTURE, BARCELONA, ES, vol. 22, no. 9, 1997, pages 956 - 968, XP000904817, ISSN: 0377-8282 [A] 1-5,8-11,14,15 * the whole document * | [YA] JAHNG Y: "Design of a new class of HMG-CoA reductase inhibitors", DRUGS OF THE FUTURE, BARCELONA, ES, vol. 20, no. 4, 1995, pages 387 - 404, XP001055605, ISSN: 0377-8282 [Y] 1,4,8,10,14 * the whole document * [A] 2,3,5,9,11,15 | [YA] ROTH B D ET AL: "Inhibitors of Cholesterol Biosynthesis. 3. Tetrahydro-4-hydroxy-6-(2- (1H-pyrrol-1-yl)ethyl)-2H-pyran-2-one Inhibitors of HMG-CoA Reductase. 2. Effects of Introducing Substituents at Positions Three and Four of the Pyrrole Nucleus", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 34, no. 1, January 1991 (1991-01-01), pages 357 - 366, XP002922115, ISSN: 0022-2623 [Y] 1,4,8,10,14 * the whole document * [A] 2,3,5,9,11,15 DOI: http://dx.doi.org/10.1021/jm00105a056 | [YA] PROCOPIOU P A ET AL.: "Inhibitors of Cholesterol Biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a Novel Series of HMG-CoA Reductase Inhibitors", JOURNAL OF MEDICINAL CHEMISTRY., vol. 36, no. 23, 1993, USAMERICAN CHEMICAL SOCIETY. WASHINGTON., pages 3658 - 3662, XP002303229 [Y] 1,4,8,10,14 * the whole document *[A] 2,3,5,9,11,15 DOI: http://dx.doi.org/10.1021/jm00075a021 | [X] HLASTA D J ET AL: "Steric Effects on the Regioselectivity of an Azide-Alkyne Dipolar Cycloaddition Reaction: The Synthesis of Human Leukocyte Elastase Inhibitors", JOURNAL OF ORGANIC CHEMISTRY., vol. 59, no. 21, 1994, USAMERICAN CHEMICAL SOCIETY. EASTON., pages 6184 - 6189, XP002313042 [X] 9 * table 3 * DOI: http://dx.doi.org/10.1021/jo00100a019 | [X] BAUDIN J B ET AL: "Unsaturated sulfinamides. X. A simple and efficient preparation of N,N-disubstituted (1-alkyne)- or (E)-(1-alkene)sulfinamides and their conversion into the corresponding sulfinates or sulfonamides", SYNLETT., no. 11, 1992, DETHIEME VERLAG, STUTTGART., pages 911 - 913, XP001204490 [X] 9 * scheme 2 * DOI: http://dx.doi.org/10.1055/s-1992-21539 | [X] BABIN P ET AL: "Electrophilic properties of sulfamoyl chloride. Application to the synthesis of .alpha.,.beta.-acetylenic sulfonamides", JOURNAL OF CHEMICAL RESEARCH. SYNOPSES, no. 1, 1982, GBLONDON, pages 16 - 17, XP009042402 [X] 9 * table 2 * | [X] ELLING H A, MAK H J: "Acetylenic sulfinamides: a novel class of compounds", SYNTHETIC COMMUNICATIONS., vol. 6, no. 2, 1976, USMARCEL DEKKER, NEW YORK, NY., pages 129 - 134, XP009042401 [X] 9 * compound 10 * DOI: http://dx.doi.org/10.1080/00397917608072622 |