EP1681302 - ANGIOGENESIS INHIBITOR, PRODUCTION PROCESS AND USE THEREOF [Right-click to bookmark this link] | |||
Former [2006/29] | NOVEL PROTEIN AND PRODUCTION PROCESS AND USE THEREOF | ||
[2010/47] | Status | No opposition filed within time limit Status updated on 05.10.2012 Database last updated on 31.08.2024 | Most recent event Tooltip | 18.07.2014 | Lapse of the patent in a contracting state New state(s): HU | published on 20.08.2014 [2014/34] | Applicant(s) | For all designated states Teijin Pharma Limited 1-1, Uchisaiwaicho 2-chome, Chiyoda-ku Tokyo 100-0011 / JP | [2006/29] | Inventor(s) | 01 /
YAMANA, Kei, c/o Teijin Pharma Limited Tokyo Research Center 3-2 Asahigaoka 4-chome Hino-shi, Tokyo 191-0065 / JP | 02 /
NAKAYAMA, Yasunori, c/o Teijin Pharma Limited Tokyo Research Center 3-2 Asahigaoka 4-chome Hino-shi, Tokyo 191-0065 / JP | 03 /
TAKAHASHI, Yoshimasa, c/o Teijin Pharma Limited Tokyo Research Center 3-2 Asahigaoka 4-chome Hino-shi, Tokyo 191-0065 / JP | 04 /
OCHIAI, Eiji, c/o Teijin Pharma Limited Tokyo Research Center 3-2 Asahigaoka 4-chome Hino-shi, Tokyo 191-0065 / JP | 05 /
WADA, Hitoshi, c/o Teijin Pharma Limited 1-1 Uchisaiwaicho 2-chome Chiyoda-ku Tokyo 100-0011 / JP | 06 /
AZUMA, Yoshiaki, c/o Teijin Pharma Limited Tokyo Research Center 3-2 Asahigaoka 4-chome Hino-shi, Tokyo 191-0065 / JP | [2011/48] |
Former [2006/29] | 01 /
YAMANA, Kei, c/o Teijin Pharma Limited Tokyo Research Center, 3-2 Asahigaoka 4-chome Hino-shi, Tokyo 191-0065 / JP | ||
02 /
NAKAYAMA, Yasunori, c/o Teijin Pharma Limited Tokyo Research Center, 3-2 Asahigaoka 4-chome Hino-shi, Tokyo 191-0065 / JP | |||
03 /
TAKAHASHI, Yoshimasa, c/o Teijin Pharma Limited Tokyo Research Center, 3-2 Asahigaoka 4-chome Hino-shi, Tokyo 191-0065 / JP | |||
04 /
OCHIAI, Eiji, c/o Teijin Pharma Limited Tokyo Research Center, 3-2 Asahigaoka 4-chome Hino-shi, Tokyo 191-0065 / JP | |||
05 /
WADA, Hitoshi, c/o Teijin Pharma Limited 1-1 Uchisaiwaicho 2-chome, Chiyoda-ku Tokyo 100-0011 / JP | |||
06 /
AZUMA, Yoshiaki, c/o Teijin Pharma Limited Tokyo Research Center, 3-2 Asahigaoka 4-chome Hino-shi, Tokyo 191-0065 / JP | Representative(s) | Hallybone, Huw George Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | [N/P] |
Former [2011/48] | Hallybone, Huw George Carpmaels & Ransford One Southampton Row London WC1B 5HA / GB | ||
Former [2009/51] | Hallybone, Huw George Carpmaels & Ransford 43-45 Bloomsbury Square London WC1A 2RA / GB | ||
Former [2006/29] | Hallybone, Huw George Carpmaels and Ransford, 43-45 Bloomsbury Square London WC1A 2RA / GB | Application number, filing date | 04792769.4 | 21.10.2004 | [2006/29] | WO2004JP15620 | Priority number, date | JP20030360617 | 21.10.2003 Original published format: JP 2003360617 | JP20040143421 | 13.05.2004 Original published format: JP 2004143421 | [2006/29] | Filing language | JA | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2005037864 | Date: | 28.04.2005 | Language: | EN | [2005/17] | Type: | A1 Application with search report | No.: | EP1681302 | Date: | 19.07.2006 | Language: | EN | The application published by WIPO in one of the EPO official languages on 28.04.2005 takes the place of the publication of the European patent application. | [2006/29] | Type: | B1 Patent specification | No.: | EP1681302 | Date: | 30.11.2011 | Language: | EN | [2011/48] | Search report(s) | International search report - published on: | JP | 28.04.2005 | (Supplementary) European search report - dispatched on: | EP | 11.05.2007 | Classification | IPC: | C07K14/47 | [2007/07] | CPC: |
C12P21/02 (EP,US);
C07K14/47 (KR);
A61P17/02 (EP);
A61P17/06 (EP);
A61P19/00 (EP);
A61P19/02 (EP);
A61P21/00 (EP);
A61P27/02 (EP);
A61P27/06 (EP);
A61P29/00 (EP);
A61P35/00 (EP);
A61P43/00 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
C07K14/4703 (EP,US);
C12N1/20 (KR);
C12N15/11 (KR);
A01K2217/05 (EP,US);
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Former IPC [2006/29] | C07K14/47, C07K19/00, C12N15/12, C12N1/21, C12N5/10, C12P21/02, G01N33/53, A01K67/027, A61K38/17, A61K48/00, A61P9/10, A61P17/02, A61P17/06, A61P19/02, A61P21/00, A61P27/02, A61P27/06, A61P29/00, A61P35/00, A61P43/00 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2006/29] | Title | German: | ANGIOGENESE-INHIBITOR, HERSTELLUNGSVERFAHREN UND VERWENDUNG DAVON | [2010/47] | English: | ANGIOGENESIS INHIBITOR, PRODUCTION PROCESS AND USE THEREOF | [2010/47] | French: | INHIBITEUR D'ANGIOGENESE, SON PROCEDE DE PRODUCTION ET SON UTILISATION | [2010/47] |
Former [2006/29] | NEUES PROTEIN UND HERSTELLUNGSVERFAHREN UND VERWENDUNG DAVON | ||
Former [2006/29] | NOVEL PROTEIN AND PRODUCTION PROCESS AND USE THEREOF | ||
Former [2006/29] | NOUVELLE PROTEINE, SON PROCEDE DE PRODUCTION ET SON UTILISATION | Entry into regional phase | 04.05.2006 | Translation filed | 04.05.2006 | National basic fee paid | 04.05.2006 | Search fee paid | 04.05.2006 | Designation fee(s) paid | 04.05.2006 | Examination fee paid | Examination procedure | 04.05.2006 | Amendment by applicant (claims and/or description) | 04.05.2006 | Examination requested [2006/29] | 16.01.2008 | Despatch of a communication from the examining division (Time limit: M06) | 28.07.2008 | Reply to a communication from the examining division | 18.03.2011 | Communication of intention to grant the patent | 19.07.2011 | Fee for grant paid | 19.07.2011 | Fee for publishing/printing paid | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 16.01.2008 | Opposition(s) | 31.08.2012 | No opposition filed within time limit [2012/45] | Fees paid | Renewal fee | 04.05.2006 | Renewal fee patent year 03 | 24.10.2007 | Renewal fee patent year 04 | 31.03.2008 | Renewal fee patent year 05 | 13.10.2009 | Renewal fee patent year 06 | 12.10.2010 | Renewal fee patent year 07 | 11.10.2011 | Renewal fee patent year 08 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 21.10.2004 | AT | 30.11.2011 | BE | 30.11.2011 | CY | 30.11.2011 | CZ | 30.11.2011 | DK | 30.11.2011 | EE | 30.11.2011 | FI | 30.11.2011 | IT | 30.11.2011 | NL | 30.11.2011 | PL | 30.11.2011 | RO | 30.11.2011 | SE | 30.11.2011 | SI | 30.11.2011 | SK | 30.11.2011 | TR | 30.11.2011 | BG | 29.02.2012 | GR | 01.03.2012 | ES | 11.03.2012 | PT | 30.03.2012 | [2014/34] |
Former [2014/21] | AT | 30.11.2011 | |
BE | 30.11.2011 | ||
CY | 30.11.2011 | ||
CZ | 30.11.2011 | ||
DK | 30.11.2011 | ||
EE | 30.11.2011 | ||
FI | 30.11.2011 | ||
IT | 30.11.2011 | ||
NL | 30.11.2011 | ||
PL | 30.11.2011 | ||
RO | 30.11.2011 | ||
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
SK | 30.11.2011 | ||
TR | 30.11.2011 | ||
BG | 29.02.2012 | ||
GR | 01.03.2012 | ||
ES | 11.03.2012 | ||
PT | 30.03.2012 | ||
Former [2013/29] | AT | 30.11.2011 | |
BE | 30.11.2011 | ||
CY | 30.11.2011 | ||
CZ | 30.11.2011 | ||
DK | 30.11.2011 | ||
EE | 30.11.2011 | ||
FI | 30.11.2011 | ||
IT | 30.11.2011 | ||
NL | 30.11.2011 | ||
PL | 30.11.2011 | ||
RO | 30.11.2011 | ||
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
SK | 30.11.2011 | ||
BG | 29.02.2012 | ||
GR | 01.03.2012 | ||
ES | 11.03.2012 | ||
PT | 30.03.2012 | ||
Former [2013/22] | AT | 30.11.2011 | |
BE | 30.11.2011 | ||
CY | 30.11.2011 | ||
CZ | 30.11.2011 | ||
DK | 30.11.2011 | ||
EE | 30.11.2011 | ||
IT | 30.11.2011 | ||
NL | 30.11.2011 | ||
PL | 30.11.2011 | ||
RO | 30.11.2011 | ||
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
SK | 30.11.2011 | ||
BG | 29.02.2012 | ||
GR | 01.03.2012 | ||
ES | 11.03.2012 | ||
PT | 30.03.2012 | ||
Former [2013/07] | AT | 30.11.2011 | |
BE | 30.11.2011 | ||
CY | 30.11.2011 | ||
CZ | 30.11.2011 | ||
DK | 30.11.2011 | ||
EE | 30.11.2011 | ||
IT | 30.11.2011 | ||
NL | 30.11.2011 | ||
PL | 30.11.2011 | ||
RO | 30.11.2011 | ||
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
SK | 30.11.2011 | ||
BG | 29.02.2012 | ||
GR | 01.03.2012 | ||
PT | 30.03.2012 | ||
Former [2012/37] | BE | 30.11.2011 | |
CY | 30.11.2011 | ||
CZ | 30.11.2011 | ||
DK | 30.11.2011 | ||
EE | 30.11.2011 | ||
IT | 30.11.2011 | ||
NL | 30.11.2011 | ||
PL | 30.11.2011 | ||
RO | 30.11.2011 | ||
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
SK | 30.11.2011 | ||
BG | 29.02.2012 | ||
GR | 01.03.2012 | ||
PT | 30.03.2012 | ||
Former [2012/36] | BE | 30.11.2011 | |
CY | 30.11.2011 | ||
CZ | 30.11.2011 | ||
DK | 30.11.2011 | ||
EE | 30.11.2011 | ||
NL | 30.11.2011 | ||
RO | 30.11.2011 | ||
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
SK | 30.11.2011 | ||
BG | 29.02.2012 | ||
GR | 01.03.2012 | ||
PT | 30.03.2012 | ||
Former [2012/35] | BE | 30.11.2011 | |
CY | 30.11.2011 | ||
CZ | 30.11.2011 | ||
DK | 30.11.2011 | ||
EE | 30.11.2011 | ||
NL | 30.11.2011 | ||
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
BG | 29.02.2012 | ||
GR | 01.03.2012 | ||
PT | 30.03.2012 | ||
Former [2012/34] | BE | 30.11.2011 | |
CY | 30.11.2011 | ||
CZ | 30.11.2011 | ||
NL | 30.11.2011 | ||
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
GR | 01.03.2012 | ||
PT | 30.03.2012 | ||
Former [2012/28] | BE | 30.11.2011 | |
CY | 30.11.2011 | ||
NL | 30.11.2011 | ||
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
GR | 01.03.2012 | ||
PT | 30.03.2012 | ||
Former [2012/25] | BE | 30.11.2011 | |
NL | 30.11.2011 | ||
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
GR | 01.03.2012 | ||
PT | 30.03.2012 | ||
Former [2012/24] | NL | 30.11.2011 | |
SE | 30.11.2011 | ||
SI | 30.11.2011 | ||
GR | 01.03.2012 | ||
PT | 30.03.2012 | ||
Former [2012/23] | NL | 30.11.2011 | |
GR | 01.03.2012 | ||
PT | 30.03.2012 | Documents cited: | Search | [X]WO0029579 (ZYMOGENETICS INC [US]) [X] 1-17,20-26 *Whole document, in particular claim 2*; | [X]EP1219710 (TEIJIN LTD [JP]) [X] 1-17,20-26 *Whole document, in particular claim 1*; | [X] - HIRAKI YUJI ET AL, "Chondromodulin-I as a novel cartilage-specific growth-modulating factor", PEDIATRIC NEPHROLOGY, (200007), vol. 14, no. 7, ISSN 0931-041X, pages 602 - 605, XP002411352 [X] 1-17,20-26 *Whole document, in particular Abstract and Figure 2* DOI: http://dx.doi.org/10.1007/s004670000339 | [X] - NAKAMICHI YUKO ET AL, "Chondromodulin I is a bone remodeling factor.", MOLECULAR AND CELLULAR BIOLOGY, (200301), vol. 23, no. 2, ISSN 0270-7306, pages 636 - 644, XP002411353 [X] 1-17,20-26 *Whole document, in particular Abstract* DOI: http://dx.doi.org/10.1128/MCB.23.2.636-644.2003 | [PX] - OSHIMA YUSUKE ET AL, "Anti-angiogenic action of the C-terminal domain of tenomodulin that shares homology with chondromodulin-I", JOURNAL OF CELL SCIENCE, (20040601), vol. 117, no. 13, ISSN 0021-9533, pages 2731 - 2744, XP002411354 [PX] 1-17,20-26 *Whole document, in particular Abstract and Discussion* DOI: http://dx.doi.org/10.1242/jcs.01112 | International search | [X]WO0123557 (TEIJIN LTD [JP], et al); | [X] - OSHIMA Y. ET AL., "Expression and localization of tenomudulin, a transmembrane type chondromodulin-I-related angiogenesis inhibitor, in mouse eyes", INVEST. OPHTHALMOL. VIS. SCI., (200305), vol. 44, no. 5, pages 1814 - 1823, XP001181222 DOI: http://dx.doi.org/10.1167/iovs.02-0664 | [X] - YAMANA K. ET AL, "Molecular cloning and characterization of CHM1L, a novel membrane molecule similar to chondromodulin-I", BIOCHEM BIOPHYS RES COMMUN, (2001), vol. 280, no. 4, pages 1101 - 1106, XP002983755 DOI: http://dx.doi.org/10.1006/bbrc.2000.4245 | [Y] - HIRAKI Y. ET AL, "Molecular cloning of human chondromodulin-I, a cartilage-derived growth modulating factor, and its expression in Chinese hamster ovary cells", EUR J BIOCHEM, (1999), vol. 260, pages 869 - 878, XP002279021 DOI: http://dx.doi.org/10.1046/j.1432-1327.1999.00227.x | [Y] - HIRAKI Y. ET AL, "Identification of chondromodulin I as a novel endothelial cell growth inhibitor. Purification and its localization in the avascular zone of epiphyseal cartilage", J BIOL CHEM, (1997), vol. 272, no. 51, pages 32419 - 32426, XP002937899 DOI: http://dx.doi.org/10.1074/jbc.272.51.32419 | [Y] - HIRAKI Y. ET AL, "Inhibition of DNA synthesis and tube morphogenesis of cultured vascular endothelial cells by chondromodulin-I", FEBS LETT., (1997), vol. 415, no. 3, pages 321 - 324, XP004261165 DOI: http://dx.doi.org/10.1016/S0014-5793(97)01151-4 | [Y] - HAYAMI T. ET AL, "Specific loss of chondromodulin-I gene expression in chondrosarcoma and the suppression of tumor angiogenesis and growth by its recombinant protein in vivo", FEBS LETT., (1999), vol. 458, no. 3, pages 436 - 440, XP004260306 DOI: http://dx.doi.org/10.1016/S0014-5793(99)01201-6 | [Y] - LIU S. ET AL, "Removal of endotoxin from recombinant protein preparations", CLIN BIOCHEM., (1997), vol. 30, no. 6, pages 455 - 463, XP002983756 DOI: http://dx.doi.org/10.1016/S0009-9120(97)00049-0 |