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Extract from the Register of European Patents

EP About this file: EP1697504

EP1697504 - USE OF IL-6-TYPE CYTOKINES FOR MATURATION OF OOCYTES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  29.06.2012
Database last updated on 09.04.2026
Most recent event   Tooltip27.09.2013Lapse of the patent in a contracting state
New state(s): TR		published on 30.10.2013  [2013/44]
Applicant(s)For all designated states
Merck Serono SA
Centre Industriel
1267 Coinsins, Vaud / CH
[2009/25]
Former [2007/40]For all designated states
Laboratoires Serono SA
Centre Industriel
1267 Coinsins, Vaud / CH
Former [2006/36]For all designated states
Applied Research Systems ARS Holding N.V.
Pietermaai 15
Curacao / AN
Inventor(s)01 / CLARK, Ann, M.
587 Broad Street
Weymouth, MA 02189 / US
02 / DE MATOS, Daniel, Gustavo
68 Chappel Street
Pembroke, MA 02359 / US
03 / JACKSON, Jennifer, A.
137 Gorham Street
Chelmsford, MA 01824 / US
04 / PALMER, Stephen, S.
81 Boston Road
Groton MA 01450 / US
05 / TRAN, Cam, Anh, T.
186 Summit Ave Apt 4
Quincy MA 02170 / US
 [2011/20]
Former [2006/36]01 / CLARK, Ann, M.
587 Broad Street
Weymouth, MA 02189 / US
02 / DE MATOS, Daniel, Gustavo
68 Chappel Street
Pembroke, MA 02359 / US
03 / JACKSON, Jennifer, A.
137 Gorham Street
Chelmsford, MA 01824 / US
04 / PALMER, Stephen, S.
67 Main Street
Plympton, MA 02367 / US
05 / TRAN, Cam, Anh, T.
50 Island View Place, Apt. 406
Dorchester, MA 02125 / US
Representative(s)Sutcliffe, Nicholas Robert, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [2006/36]Sutcliffe, Nicholas Robert, et al
Mewburn Ellis LLP York House, 23 Kingsway
London WC2B 6HP / GB
Application number, filing date04812306.126.11.2004
[2006/36]
WO2004US39757
Priority number, dateUS20030525279P26.11.2003         Original published format: US 525279 P
[2006/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2005054449
Date:16.06.2005
Language:EN
[2005/24]
Type: A1 Application with search report 
No.:EP1697504
Date:06.09.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 16.06.2005 takes the place of the publication of the European patent application.
[2006/36]
Type: B1 Patent specification 
No.:EP1697504
Date:24.08.2011
Language:EN
[2011/34]
Search report(s)International search report - published on:EP16.06.2005
ClassificationIPC:C12N5/075, C07K14/54
[2011/14]
CPC:
C12N5/0609 (EP,NO,US); C07K14/5412 (EP,NO,US); A61P15/08 (EP);
C12N2501/175 (EP,US); C12N2501/2306 (EP,US); C12N2501/235 (EP,US);
C12N2501/237 (EP,US); C12N2501/31 (EP,US) (-)
Former IPC [2006/36]C12N5/08, C07K14/54
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/36]
Extension statesAL09.06.2006
HR09.06.2006
LT09.06.2006
LV09.06.2006
MK09.06.2006
YU09.06.2006
TitleGerman:VERWENDUNG VON IL-6-TYP-CYTOKINEN ZUR REIFUNG VON OOZYTEN[2006/36]
English:USE OF IL-6-TYPE CYTOKINES FOR MATURATION OF OOCYTES[2006/36]
French:USAGE DE CYTOKINES DU TYPE IL-6 POUR LA MATURATION DES OOCYTES[2006/36]
Entry into regional phase09.06.2006National basic fee paid 
09.06.2006Designation fee(s) paid 
09.06.2006Examination fee paid 
Examination procedure09.06.2006Examination requested  [2006/36]
12.06.2008Despatch of a communication from the examining division (Time limit: M04)
01.10.2008Reply to a communication from the examining division
03.03.2009Despatch of a communication from the examining division (Time limit: M06)
20.07.2009Reply to a communication from the examining division
19.04.2010Despatch of a communication from the examining division (Time limit: M06)
21.10.2010Reply to a communication from the examining division
17.02.2011Despatch of a communication from the examining division (Time limit: M02)
24.02.2011Reply to a communication from the examining division
23.03.2011Communication of intention to grant the patent
13.07.2011Fee for grant paid
13.07.2011Fee for publishing/printing paid
Divisional application(s)EP10177394.3  / EP2325201
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  12.06.2008
Opposition(s)25.05.2012No opposition filed within time limit [2012/31]
Fees paidRenewal fee
22.11.2006Renewal fee patent year 03
15.11.2007Renewal fee patent year 04
12.11.2008Renewal fee patent year 05
12.11.2009Renewal fee patent year 06
12.11.2010Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY24.08.2011
EE24.08.2011
RO24.08.2011
SI24.08.2011
SK24.08.2011
TR24.08.2011
BG24.11.2011
GR25.11.2011
LU26.11.2011
MC30.11.2011
IS24.12.2011
[2013/44]
Former [2013/29]CY24.08.2011
EE24.08.2011
RO24.08.2011
SI24.08.2011
SK24.08.2011
BG24.11.2011
GR25.11.2011
LU26.11.2011
MC30.11.2011
IS24.12.2011
Former [2013/25]CY24.08.2011
EE24.08.2011
RO24.08.2011
SI24.08.2011
SK24.08.2011
GR25.11.2011
LU26.11.2011
MC30.11.2011
IS24.12.2011
Former [2012/29]CY24.08.2011
EE24.08.2011
RO24.08.2011
SI24.08.2011
SK24.08.2011
GR25.11.2011
MC30.11.2011
IS24.12.2011
Former [2012/23]CY24.08.2011
EE24.08.2011
RO24.08.2011
SI24.08.2011
SK24.08.2011
GR25.11.2011
IS24.12.2011
Former [2012/12]CY24.08.2011
SI24.08.2011
GR25.11.2011
IS24.12.2011
Former [2012/11]SI24.08.2011
GR25.11.2011
IS24.12.2011
Former [2012/10]GR25.11.2011
IS24.12.2011
Former [2012/08]IS24.12.2011
Cited inInternational search[Y]   KAWASAKI F ET AL: "The clinical role of interleukin-6 and interleukin-6 soluble receptor in human follicular fluids.", CLINICAL AND EXPERIMENTAL MEDICINE, vol. 3, no. 1, May 2003 (2003-05-01), pages 27 - 31, XP002324021, ISSN: 1591-8890 [Y] 1-15 * page 30, column RIGHT, paragraph LAST *

DOI:   http://dx.doi.org/10.1007/s102380300012
 [Y]   SUTTON M L ET AL: "Effects of in-vivo and in-vitro environments on the metabolism of the cumulus-oocyte complex and its influence on oocyte developmental capacity.", HUMAN REPRODUCTION UPDATE. 2003 JAN-FEB, vol. 9, no. 1, January 2003 (2003-01-01), pages 35 - 48, XP002324022, ISSN: 1355-4786 [Y] 1-15 * page 44, paragraph LAST *

DOI:   http://dx.doi.org/10.1093/humupd/dmg009
 [A]   PICTON H M ET AL: "Growth and maturation of oocytes in vitro.", REPRODUCTION (CAMBRIDGE, ENGLAND) SUPPLEMENT. 2003, vol. 61, August 2003 (2003-08-01), pages 445 - 462, XP009046163, ISSN: 1477-0415 [A] 1-15 * the whole document *
 [A]   ZOLTI M., ET AL.: "cytokine involvement in oocytes and early embryos", FERTILITY AND STERILITY, vol. 56, no. 2, August 1991 (1991-08-01), pages 265 - 272, XP009046158 [A] 1-15 * the whole document *
 [A]   ECKERT J ET AL: "mRNA expression of leukaemia inhibitory factor (LIF) and its receptor subunits glycoprotein 130 and LIF-receptor-beta in bovine embryos derived in vitro or in vivo.", MOLECULAR HUMAN REPRODUCTION. OCT 1998, vol. 4, no. 10, October 1998 (1998-10-01), pages 957 - 965, XP002324025, ISSN: 1360-9947 [A] 1-15

DOI:   http://dx.doi.org/10.1093/molehr/4.10.957
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.