EP1621207 - Mixture of defibrotide and G-CSF, and its use for activating haematopoietic progenitors [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 30.07.2010 Database last updated on 02.09.2024 | Most recent event Tooltip | 19.10.2012 | Lapse of the patent in a contracting state New state(s): TR | published on 21.11.2012 [2012/47] | Applicant(s) | For all designated states Gentium S.p.A. Piazza XX Settembre 2 22079 Villa Guardia (Como) / IT | [2006/05] | Inventor(s) | 01 /
FERRO, Laura Piazza Brera 24/6 I-20100, MILANO (MI) / IT | 02 /
PORTA, Roberto Via Aquileia 1 I-22012, CERNOBBIO (CO) / IT | 03 /
IACOBELLI, Massimo Via Forze Armate 260/3 I-20152, MILANO (MI) / IT | 04 /
GIANNI, Alessandro Massimo Via L. Muratori 29 I-20135, MILANO (MI) / IT | 05 /
STELLA, Carmelo Carlo Via Eustachi 47 I-20129, MIlano (MI) / IT | [2006/05] | Representative(s) | Pistolesi, Roberto, et al Dragotti & Associati Srl Via Nino Bixio, 7 20129 Milano / IT | [N/P] |
Former [2006/05] | Pistolesi, Roberto, et al Dragotti & Associati srl Via Turati 32 20121 Milano / IT | Application number, filing date | 05108424.2 | 10.04.2001 | [2006/05] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP1621207 | Date: | 01.02.2006 | Language: | EN | [2006/05] | Type: | A3 Search report | No.: | EP1621207 | Date: | 22.11.2006 | [2006/47] | Type: | B1 Patent specification | No.: | EP1621207 | Date: | 23.09.2009 | Language: | EN | [2009/39] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 19.10.2006 | Classification | IPC: | A61K38/19, A61P7/00, C12N5/06, // A61K31/70 | [2006/47] | CPC: |
A61K31/70 (EP,US);
A61K38/19 (KR);
A61K38/193 (EP,US);
A61P35/00 (EP);
A61P43/00 (EP);
A61P7/00 (EP);
A61P7/06 (EP)
(-)
| C-Set: |
A61K31/70, A61K2300/00 (EP,US);
A61K38/193, A61K2300/00 (US,EP) |
Former IPC [2006/05] | A61K38/19, A61P7/00, A61K31/70 | Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2006/05] | Extension states | AL | 17.04.2007 | LT | 17.04.2007 | LV | 17.04.2007 | MK | 17.04.2007 | Title | German: | Kombination von Defibrotide und G-CSF und ihre Verwendung zur Aktivierung hämatopoietischer Vorläuferzellen | [2006/47] | English: | Mixture of defibrotide and G-CSF, and its use for activating haematopoietic progenitors | [2006/05] | French: | Composition de défibrotide et de G-CSF et son utilisation pour l'activation des progéniteurs hématopoiétiques | [2006/05] |
Former [2006/05] | kombination von Defibrotide und G-CSF und ihre Verwendung zur Aktivierung hämatopoietischer Vorläuferzellen | Examination procedure | 17.04.2007 | Examination requested [2007/22] | 22.05.2007 | Despatch of a communication from the examining division (Time limit: M06) | 09.01.2008 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 15.02.2008 | Reply to a communication from the examining division | 25.03.2009 | Cancellation of oral proceeding that was planned for 31.03.2009 | 25.03.2009 | Minutes of oral proceedings despatched | 31.03.2009 | Date of oral proceedings | 31.03.2009 | Date of oral proceedings (cancelled) | 06.05.2009 | Communication of intention to grant the patent | 17.08.2009 | Fee for grant paid | 17.08.2009 | Fee for publishing/printing paid | Parent application(s) Tooltip | EP01931582.9 / EP1276497 | Opposition(s) | 24.06.2010 | No opposition filed within time limit [2010/35] | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 15.02.2008 | Request for further processing filed | 15.02.2008 | Full payment received (date of receipt of payment) Request granted | 17.03.2008 | Decision despatched | Fees paid | Renewal fee | 04.10.2005 | Renewal fee patent year 03 | 04.10.2005 | Renewal fee patent year 04 | 04.10.2005 | Renewal fee patent year 05 | 26.04.2006 | Renewal fee patent year 06 | 26.04.2007 | Renewal fee patent year 07 | 26.03.2008 | Renewal fee patent year 08 | 24.04.2009 | Renewal fee patent year 09 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | CY | 23.09.2009 | FI | 23.09.2009 | TR | 23.09.2009 | IE | 10.04.2010 | MC | 30.04.2010 | [2012/47] |
Former [2011/07] | CY | 23.09.2009 | |
FI | 23.09.2009 | ||
IE | 10.04.2010 | ||
MC | 30.04.2010 | ||
Former [2010/52] | CY | 23.09.2009 | |
FI | 23.09.2009 | ||
MC | 30.04.2010 | ||
Former [2010/16] | CY | 23.09.2009 | |
FI | 23.09.2009 | ||
Former [2010/11] | FI | 23.09.2009 | Documents cited: | Search | [A]EP0317766 (CRINOS INDUSTRIA FARMACO [IT]) [A] 1-9 * claims 1-13 *; | [A]EP0416678 (CRINOS INDUSTRIA FARMACO [IT]) [A] 1-9 * claims 1-6 *; | [Y]US5199942 (GILLIS STEVEN [US]) [Y] 1-9 * claims 1-17 *; | [A]WO9926639 (ALLEGHENY UNIVERSITY OF THE HE [US], et al) [A] 1-9 * claims 1-15 *; | [Y]US5977083 (BURCOGLU ARSINUR [US]) [Y] 1-9 * claims 1-25 *; | [A] - GURSOY A, "PREPARATION, CHARACTERIZATION AND ANTI-INFLAMMATORY EFFECT OF DEFIBROTIDE LIPOSOMES", PHARMAZIE,DD,VEB VERLAG VOLK UND GESUNDHEIT. BERLIN, (19930701), vol. 48, no. 7, ISSN 0031-7144, pages 549 - 550, XP000372658 [A] 1-9 * abstract * | [T] - CARLO-STELLA, C. (1) ET AL, "Defibrotide significantly enhances peripheral blood progenitor cell mobilization induced by recombinant human granulocyte colony - stimulating factor ( rhG - CSF.", BLOOD, PART 1, PP. 553A. PRINT. MEETING INFO.: 42ND ANNUAL MEETING OF THE AMERICAN SOCIETY OF HEMATOLOGY SAN FRANCISCO, CALIFORNIA, USA DECEMBER 01-05, 2000 AMERICAN SOCIETY OF HEMATOLOGY., (20001116), vol. 96, no. 11, XP002176349 [T] 1-9 * abstract * | by applicant | US3770720 | US3829567 | US3899481 | US4694134 | US4693995 | US4985552 | US5223609 | - C.F. CRADDOCK, "Antibodies to VLA4 Integrin Mobilize Long-Term Repopulating Cells and Augment Cytokine-Induced Mobilization in Primates and Mice", BLOOD, (1997), vol. 90, no. 12, pages 4779 - 4788 | - F. PROSPER, "Mobilization and Homing of Peripheral Blood Progenitors is Related to Reversible Downregulation of a4ß1 Integrin Expression and Function", J. CLIN. INVEST., (1998), vol. 101, no. 11, pages 2456 - 2467 | - M. VERMEULEN, "Role of Adhesion Molecules in the Homing and Mobilization of Murine Hematopoietic Stem and Progenitor Cells", BLOOD, (1998), vol. 92, no. 3, pages 894 - 900 | - CAS REGISTRY NUMBER 143011-2-7/MERCK INDEX, (1996), page 4558 |