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Extract from the Register of European Patents

EP About this file: EP1627635

EP1627635 - Benzothiazolium compounds for use in methods of inhibiting NO production and TNF alpha and treating coronaviral infection [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.08.2010
Database last updated on 20.12.2024
Most recent event   Tooltip19.10.2012Lapse of the patent in a contracting state
New state(s): TR		published on 21.11.2012  [2012/47]
Applicant(s)For all designated states
National Health Research Institutes
35 Keyan Road
Zhunan Town, Miaoli Country / TW
[2006/08]
Inventor(s)01 / Lee, Shiow-Ju
No.5, Lane 184 Kunshen road
Tainan / TW
02 / Yang, Yung-Ning
No.13, Lane 71 Wunhua Road
Sindian City, Taipei / TW
 [2006/08]
Representative(s)Nargolwalla, Cyra
Cabinet Plasseraud
ATTENTION : ADDRESS INACTIVE - USE ASS-NR - CDR
Paris / FR
[N/P]
Former [2006/08]Nargolwalla, Cyra
Cabinet Plasseraud 65/67 rue de la Victoire
75440 Paris Cedex 09 / FR
Application number, filing date05291733.316.08.2005
[2006/08]
Priority number, dateUS20040601390P13.08.2004         Original published format: US 601390 P
[2006/08]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP1627635
Date:22.02.2006
Language:EN
[2006/08]
Type: A3 Search report 
No.:EP1627635
Date:29.03.2006
[2006/13]
Type: B1 Patent specification 
No.:EP1627635
Date:07.10.2009
Language:EN
[2009/41]
Search report(s)(Supplementary) European search report - dispatched on:EP13.02.2006
ClassificationIPC:A61K31/428, A61P31/12, C07D277/62
[2006/08]
CPC:
A61K31/47 (EP,US); A61K31/428 (EP,US); A61P31/12 (EP);
C09B23/0008 (EP,US); C09B23/0025 (EP,US); C09B23/0083 (EP,US);
C09B23/04 (EP,US); C09B23/06 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/08]
Extension statesAL02.09.2006
BA02.09.2006
HR02.09.2006
MK02.09.2006
YU02.09.2006
TitleGerman:Benzothiazolium Verbindungen zur Verwendung in Methoden zur Hemmung der NO Produktion und von TNF alpha und zur Behandlung von Coronavirus Infektionen[2006/08]
English:Benzothiazolium compounds for use in methods of inhibiting NO production and TNF alpha and treating coronaviral infection[2006/08]
French:Composés de benzothiazolium utilisés dans des méthodes pour l'inhibition de la production de NO et du TNF alpha et pour le traitement des infections à coronavirus[2006/08]
Examination procedure24.08.2005Examination requested  [2006/08]
28.09.2006Despatch of a communication from the examining division (Time limit: M06)
27.03.2007Reply to a communication from the examining division
07.08.2008Despatch of a communication from the examining division (Time limit: M02)
09.10.2008Reply to a communication from the examining division
31.10.2008Despatch of a communication from the examining division (Time limit: M02)
09.01.2009Reply to a communication from the examining division
16.03.2009Communication of intention to grant the patent
15.07.2009Fee for grant paid
15.07.2009Fee for publishing/printing paid
Opposition(s)08.07.2010No opposition filed within time limit [2010/37]
Fees paidRenewal fee
13.08.2007Renewal fee patent year 03
25.08.2008Renewal fee patent year 04
25.08.2009Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT07.10.2009
BE07.10.2009
CY07.10.2009
CZ07.10.2009
DK07.10.2009
EE07.10.2009
FI07.10.2009
IT07.10.2009
LT07.10.2009
LV07.10.2009
NL07.10.2009
PL07.10.2009
RO07.10.2009
SE07.10.2009
SI07.10.2009
SK07.10.2009
TR07.10.2009
BG07.01.2010
GR08.01.2010
ES18.01.2010
IS07.02.2010
PT08.02.2010
HU08.04.2010
[2012/47]
Former [2012/42]AT07.10.2009
BE07.10.2009
CY07.10.2009
CZ07.10.2009
DK07.10.2009
EE07.10.2009
FI07.10.2009
IT07.10.2009
LT07.10.2009
LV07.10.2009
NL07.10.2009
PL07.10.2009
RO07.10.2009
SE07.10.2009
SI07.10.2009
SK07.10.2009
BG07.01.2010
GR08.01.2010
ES18.01.2010
IS07.02.2010
PT08.02.2010
HU08.04.2010
Former [2012/37]AT07.10.2009
BE07.10.2009
CY07.10.2009
CZ07.10.2009
DK07.10.2009
EE07.10.2009
FI07.10.2009
IT07.10.2009
LT07.10.2009
LV07.10.2009
NL07.10.2009
PL07.10.2009
RO07.10.2009
SE07.10.2009
SI07.10.2009
SK07.10.2009
BG07.01.2010
GR08.01.2010
ES18.01.2010
IS07.02.2010
PT08.02.2010
Former [2011/15]AT07.10.2009
BE07.10.2009
CZ07.10.2009
DK07.10.2009
EE07.10.2009
FI07.10.2009
IT07.10.2009
LT07.10.2009
LV07.10.2009
NL07.10.2009
PL07.10.2009
RO07.10.2009
SE07.10.2009
SI07.10.2009
SK07.10.2009
BG07.01.2010
GR08.01.2010
ES18.01.2010
IS07.02.2010
PT08.02.2010
Former [2010/52]AT07.10.2009
BE07.10.2009
CZ07.10.2009
DK07.10.2009
EE07.10.2009
FI07.10.2009
LT07.10.2009
LV07.10.2009
NL07.10.2009
PL07.10.2009
RO07.10.2009
SE07.10.2009
SI07.10.2009
SK07.10.2009
BG07.01.2010
GR08.01.2010
ES18.01.2010
IS07.02.2010
PT08.02.2010
Former [2010/39]AT07.10.2009
BE07.10.2009
CZ07.10.2009
DK07.10.2009
EE07.10.2009
FI07.10.2009
LT07.10.2009
LV07.10.2009
NL07.10.2009
PL07.10.2009
RO07.10.2009
SE07.10.2009
SI07.10.2009
SK07.10.2009
BG07.01.2010
ES18.01.2010
IS07.02.2010
PT08.02.2010
Former [2010/33]AT07.10.2009
BE07.10.2009
FI07.10.2009
LT07.10.2009
LV07.10.2009
NL07.10.2009
PL07.10.2009
SE07.10.2009
SI07.10.2009
ES18.01.2010
IS07.02.2010
PT08.02.2010
Former [2010/29]AT07.10.2009
BE07.10.2009
FI07.10.2009
LT07.10.2009
LV07.10.2009
PL07.10.2009
SE07.10.2009
SI07.10.2009
ES18.01.2010
IS07.02.2010
PT08.02.2010
Former [2010/25]FI07.10.2009
LT07.10.2009
LV07.10.2009
PL07.10.2009
SE07.10.2009
SI07.10.2009
ES18.01.2010
IS07.02.2010
PT08.02.2010
Former [2010/23]FI07.10.2009
LT07.10.2009
PL07.10.2009
SE07.10.2009
SI07.10.2009
ES18.01.2010
IS07.02.2010
PT08.02.2010
Former [2010/21]LT07.10.2009
SE07.10.2009
SI07.10.2009
ES18.01.2010
IS07.02.2010
PT08.02.2010
Former [2010/19]SI07.10.2009
ES18.01.2010
Former [2010/14]SI07.10.2009
Documents cited:Search[A]WO0158897  (DARWIN DISCOVERY LTD [GB]) [A] 1-38 * page 1, line 11 - page 2, line 15 *;
 [A]  - CHEN H-F ET AL, "DISCOVERY OF ANTI-SARS CORONAVIRUS DRUG BASED ON MOLECULAR DOCKING AND DATABASE SCREENING", CHINESE JOURNAL OF CHEMISTRY, (2004), vol. 22, no. 8, pages 882 - 887, XP008035036 [A] 1-38 * table 2 compound A4 *
 [A]  - NG PAK C ET AL, "Inflammatory cytokine profile in children with severe acute respiratory syndrome.", PEDIATRICS. JAN 2004, (200401), vol. 113, no. 1 Pt 1, ISSN 1098-4275, pages e7 - 14, XP002364277 [A] 1-38 * page e14, paragraph entitled "Conclusions" *
 [PX]  - TSENG H-Y ET AL, "Benzothiazolium compounds: novel classes of inhibitors that suppress the nitric oxide production in RAW264.7 cells stimulated by LPS/IFNgamma", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, (20050415), vol. 15, no. 8, ISSN 0960-894X, pages 2027 - 2032, XP004829167 [PX] 1-16 * table 1-5 *

DOI:   http://dx.doi.org/10.1016/j.bmcl.2005.02.063
 [PA]  - BLANCHARD J E ET AL, "High-Throughput Screening Identifies Inhibitors of the SARS Coronavirus Main Proteinase", CHEMISTRY AND BIOLOGY, CURRENT BIOLOGY, LONDON, GB, (200410), vol. 11, no. 10, ISSN 1074-5521, pages 1445 - 1453, XP004601878 [PA] 1-38 * table 2, compound MAC-8120 *

DOI:   http://dx.doi.org/10.1016/j.chembiol.2004.08.011
by applicantWO0158897
    - CHEN H-F ET AL., "DISCOVERY OF ANTI-SARS CORONA VIRUS DRUG BASED ON MOLECULAR DOCKING AND DATABASE SCREENING", CHINESE JOURNAL OF CHEMISTRY, (2004), vol. 22, no. 8, pages 882 - 887
    - NG PAK C ET AL., "Inflammatory cytokine profile in children with severe acute respiratory syndrome", PEDIATRICS., (200401), vol. 113, no. 1, pages E7 - 14
    - KUO ET AL., BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, (2004), vol. 318, pages 862 - 867
 US20040601390
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.