EP1721908 - NOVEL METHOD OF SYNTHESIZING NUCLEIC ACID WITHOUT PROTECTING NUCLEOTIDE BASES [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 03.01.2014 Database last updated on 26.04.2025 | Most recent event Tooltip | 03.01.2014 | Application deemed to be withdrawn | published on 05.02.2014 [2014/06] | Applicant(s) | For all designated states Japan Science and Technology Agency 4-1-8-, Honcho Kawaguchi-shi Saitama 332-0012 / JP | [2006/46] | Inventor(s) | 01 /
SEKINE, Mitsuo 1-26-46, Azamino,Aoba-ku, Yokohama-shi Kanagawa 225-0011 / JP | 02 /
SEIO, Kohji, Daini Parkside Uchida 102 48-5, Shiratoridai Aoba-ku, Yokohama-shi Kanagawa 227-0054 / JP | 03 /
OHKUBO, Akihiro 1-10-5-202, Ogawa,Machida-shi Tokyo 194-0003 / JP | [2006/46] | Representative(s) | Strehl & Partner mbB Maximilianstrasse 54 80538 München / DE | [N/P] |
Former [2006/46] | Strehl Schübel-Hopf & Partner Maximilianstrasse 54 80538 München / DE | Application number, filing date | 05710654.4 | 24.02.2005 | [2006/46] | WO2005JP03053 | Priority number, date | JP20040056707 | 01.03.2004 Original published format: JP 2004056707 | [2006/46] | Filing language | JA | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2005082923 | Date: | 09.09.2005 | Language: | EN | [2005/36] | Type: | A1 Application with search report | No.: | EP1721908 | Date: | 15.11.2006 | Language: | EN | The application published by WIPO in one of the EPO official languages on 09.09.2005 takes the place of the publication of the European patent application. | [2006/46] | Search report(s) | International search report - published on: | JP | 09.09.2005 | (Supplementary) European search report - dispatched on: | EP | 13.11.2009 | Classification | IPC: | C07H21/04, C12N15/09 | [2006/46] | CPC: |
C07H21/04 (EP,US)
| Designated contracting states | DE, FR, GB [2007/23] |
Former [2006/46] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR | Extension states | AL | Not yet paid | BA | Not yet paid | HR | Not yet paid | LV | Not yet paid | MK | Not yet paid | YU | Not yet paid | Title | German: | NEUES VERFAHREN ZUR SYNTHESE VON NUKLEINSÄUREN OHNE SCHÜTZEN DER NUKLEOTIDBASEN | [2006/46] | English: | NOVEL METHOD OF SYNTHESIZING NUCLEIC ACID WITHOUT PROTECTING NUCLEOTIDE BASES | [2006/46] | French: | NOUVEAU PROCEDE DE SYNTHESE D' ACIDE NUCLEIQUE SANS PROTEGER LES BASES DES NUCLEOTIDES | [2006/46] | Entry into regional phase | 04.09.2006 | Translation filed | 22.09.2006 | National basic fee paid | 22.09.2006 | Search fee paid | 22.09.2006 | Designation fee(s) paid | 22.09.2006 | Examination fee paid | Examination procedure | 26.12.2005 | Request for preliminary examination filed International Preliminary Examining Authority: JP | 04.09.2006 | Amendment by applicant (claims and/or description) | 22.09.2006 | Examination requested [2006/46] | 30.09.2010 | Despatch of a communication from the examining division (Time limit: M06) | 07.04.2011 | Reply to a communication from the examining division | 03.09.2013 | Application deemed to be withdrawn, date of legal effect [2014/06] | 25.09.2013 | Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2014/06] | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 30.09.2010 | Fees paid | Renewal fee | 13.02.2007 | Renewal fee patent year 03 | 20.02.2008 | Renewal fee patent year 04 | 19.02.2009 | Renewal fee patent year 05 | 23.02.2010 | Renewal fee patent year 06 | 24.02.2011 | Renewal fee patent year 07 | 22.02.2012 | Renewal fee patent year 08 | Penalty fee | Additional fee for renewal fee | 28.02.2013 | 09   M06   Not yet paid |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X] - OHKUBO A ET AL, "A new approach for pyrophosphate bond formation starting from phosphoramidite derivatives by use of 6-trifluoromethyl-1-hydroxybenz otriazole-mediated O-N phosphoryl migration", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, (20040126), vol. 45, no. 5, ISSN 0040-4039, pages 979 - 982, XP004483304 [X] 1,3-5 * page 979 - page 982 * DOI: http://dx.doi.org/10.1016/j.tetlet.2003.11.110 | [X] - SEIO K ET AL, "Enhanced stereoselectivity in internucleosidic bond formation by the use of the chiral ribose moiety of thymidine", JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, EASTON.; US, (20030101), vol. 68, ISSN 0022-3263, pages 3849 - 3859, XP002328262 [X] 1-8 * page 3850 - page 3855 * DOI: http://dx.doi.org/10.1021/jo020533l | [X] - M. SEKINE ET AL., "proton-block strategy for the synthesis of oligodeoxynucleotides without base protection", JOURNAL OF ORGANIC CHEMISTRY, usa, (2003), vol. 68, no. 14, pages 5478 - 5492, XP002553901 [X] 1-8 * page 5479 - page 5482; tables sch.2a,3a * DOI: http://dx.doi.org/10.1021/jo034204k | [X] - A. OHKUBO ET AL., "a new strategy for the synthesis of oligodeoxynucleotides in the phosphoramidite method", NUCLEIC ACID RESEARCH SUPPLEMENT, gb, (2002), vol. 2, pages 29 - 30, XP002553902 [X] 1,3 * page 29 - page 30 * DOI: http://dx.doi.org/10.1093/nass/2.1.29 | International search | [A]JPS6251695 (YUKI GOSEI YAKUHIN KOGYO KK); | [Y]JPH1180185 (JAPAN RES DEV CORP); | [Y]JP2003002895 (TOKYO INST TECH); | [X]JP2003028871 (FUJI PHOTO FILM CO LTD); | [XP]JP2004099532 (SIGMA GENOSYS JAPAN KK); | [X] - OHKUBO A. ET AL., "A new strategy for the synthesis of oligodeoxynucleotides directed towards perfect O selective internucleotidic bond formation without base protection.", TETRAHEDRON LETTERS., (2004), vol. 45, no. 2, pages 363 - 366, XP004478904 DOI: http://dx.doi.org/10.1016/j.tetlet.2003.10.156 | [X] - DABKOWSKI W. ET AL., "2,4-dinitrophenol: a novel activating reagent in nucleotide synthesis via the phosphoramidite route.", TETRAHEDRON LETTERS., (2000), vol. 41, no. 39, pages 7535 - 7539, XP004217345 DOI: http://dx.doi.org/10.1016/S0040-4039(00)01178-3 |