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Extract from the Register of European Patents

EP About this file: EP1725869

EP1725869 - MAN2AS AS MODIFIERS OF THE IGER PATHWAY AND METHODS OF USE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  30.05.2008
Database last updated on 22.08.2024
Most recent event   Tooltip30.05.2008Application deemed to be withdrawnpublished on 02.07.2008  [2008/27]
Applicant(s)For all designated states
Exelixis, Inc.
170 Harbor Way
South San Francisco, CA 94083-0511 / US
For all designated states
Heuer, Timothy S.
581A Paloma Avenue
Pacifica, California 94044 / US
[2006/48]
Inventor(s)01 / FRIEDMAN, Lori
113 Arundel Road
San Carlos, California 94070 / US
02 / FRANCIS-LANG, Helen
1782 Pacific Avenue, 2
San Francisco, California 94109 / US
03 / PARKS, Annette
35 Ripley Street
Newton, MA 02459 / US
04 / SHAW, Kenneth James
484 Sierra Point Road
Brisbane, California 94005 / US
05 / ZHANG, HaiGuang
922 Bridgeway Circle
El Sobrante, CA 94803 / US
 [2006/48]
Representative(s)Main, Malcolm Charles
Murgitroyd & Company
Scotland House
165-169 Scotland Street
Glasgow G5 8PL / GB
[N/P]
Former [2006/48]Main, Malcolm Charles
Murgitroyd & Company Scotland House 165-169 Scotland Street
Glasgow G5 8PL / GB
Application number, filing date05722721.727.01.2005
[2006/48]
WO2005US03483
Priority number, dateUS20040539837P28.01.2004         Original published format: US 539837 P
[2006/48]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2005073725
Date:11.08.2005
Language:EN
[2005/32]
Type: A1 Application with search report 
No.:EP1725869
Date:29.11.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 11.08.2005 takes the place of the publication of the European patent application.
[2006/48]
Search report(s)International search report - published on:US11.08.2005
(Supplementary) European search report - dispatched on:EP04.10.2007
ClassificationIPC:G01N33/53, G01N33/566, C12Q1/34
[2007/44]
CPC:
C12Q1/34 (EP,US); A61P3/10 (EP); A61P35/00 (EP);
A61P43/00 (EP); A61P5/50 (EP); G01N2500/00 (EP,US)
Former IPC [2006/48]G01N33/53, G01N33/566
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/48]
Extension statesAL26.07.2006
BA26.07.2006
HR26.07.2006
LV26.07.2006
MK26.07.2006
YU26.07.2006
TitleGerman:MAN2AS ALS MODIFIKATOREN DES IGER-WEGS UND VERWENDUNGSVERFAHREN[2006/48]
English:MAN2AS AS MODIFIERS OF THE IGER PATHWAY AND METHODS OF USE[2006/48]
French:MAN2A UTILISES COMME MODIFICATEURS DE LA VOIE IGFR ET LEUR PROCEDE D'UTILISATION[2006/48]
Entry into regional phase26.07.2006National basic fee paid 
26.07.2006Search fee paid 
26.07.2006Designation fee(s) paid 
26.07.2006Examination fee paid 
Examination procedure26.07.2006Examination requested  [2006/48]
27.12.2007Application deemed to be withdrawn, date of legal effect  [2008/27]
11.02.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2008/27]
Fees paidRenewal fee
12.01.2007Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.01.200804   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]WO0175067  (HYSEQ INC [US], et al) [X] 20-25 * sequence 12220 * * page 53, paragraph 1 * * page 20, line 25 - page 24, line 24 * * page 37, line 29 - page 38, line 15 *;
 [X]US2002172670  (ROSE DAVID RICHARD [CA], et al) [X] 20-22 * claims 40,41 * * paragraphs [0012] , [0217] , [0286] , [0287] *;
 [X]  - VAN DEN ELSEN JEAN M H ET AL, "Structure of Golgi alpha-mannosidase II: A target for inhibition of growth and metastasis of cancer cells", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, (20010615), vol. 20, no. 12, ISSN 0261-4189, pages 3008 - 3017, XP008082326 [X] 20-22 * page 3008, column 1, paragraph 1 - column 2 *

DOI:   http://dx.doi.org/10.1093/emboj/20.12.3008
 [X]  - GOSS P E ET AL, "INHIBITORS OF CARBOHYDRATE PROCESSING: A NEW CLASS OF ANTICANCER AGENTS", ELECTRONIC AND COMPUTING MONTHLY, EMAP BUSINESS & COMPUTER PUBL. PETERBOROUGH, GB, (199509), vol. 1, ISSN 0264-5513, pages 935 - 944, XP001051571 [X] 20-22 * abstract * * page 937, column 2, paragraphs 2,3 *
 [X]  - GOSS PAUL E ET AL, "A phase I study of swainsonine in patients with advanced malignancies", CANCER RESEARCH, (1994), vol. 54, no. 6, ISSN 0008-5472, pages 1450 - 1457, XP008082333 [X] 20-22 * abstract *
 [X]  - GOSS P E ET AL, "Phase IB clinical trial of the oligosaccharide processing inhibitor swainsonine in patients with advanced malignancies", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (199707), vol. 3, no. 7, ISSN 1078-0432, pages 1077 - 1086, XP008082322 [X] 20-22 * abstract *
 [X]  - KIESS W ET AL, "BIOSYNTHESIS OF THE INSULIN-LIKE GROWTH FACTOR-II IGF-II MANNOSE-6-PHOSPHATERECEPTOR IN RAT C6 GLIAL CELLS THE ROLE OF N-LINKED GLYCOSYLATION IN BINDINGOF IGF-II TO THE RECEPTOR", MOLECULAR ENDOCRINOLOGY, BALTIMORE, MD, US, (1991), vol. 5, no. 2, ISSN 0888-8809, pages 281 - 291, XP008082302 [X] 1,2,4 * abstract * * page 282, column 2, paragraph 2 - page 283, column 2 *
 [A]  - MISUMI Y., "Homo sapiens mRNA for golgi alpha-mannosidaseII, complete cds", EMBL, (19950906), Database accession no. D63998, XP002450239 [A] 1-25 * column A *
 [A]  - MISAGO M ET AL, "Molecular cloning and expression of cDNAs encoding human alpha-mannosidase II and a previously unrecognized alpha-mannosidase IIx isozyme", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, (199512), vol. 92, ISSN 0027-8424, pages 11766 - 11770, XP002239755 [A] 1-25 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.92.25.11766
 [A]  - ZHAO HONG ET AL, "PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells.", ONCOGENE, (20040122), vol. 23, no. 3, ISSN 0950-9232, pages 786 - 794, XP008083876 [A] 1-25 * the whole document *

DOI:   http://dx.doi.org/10.1038/sj.onc.1207162
International search[A]  - KANG ET AL, "Retinoic acid alters the intracelluar trafficking of the mannose-6-phosphate/insulin-like growth factor li receptor and lysosomal enzymes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (199811), vol. 95, pages 13687 - 13691
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.