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EP About this file: EP1766393

EP1766393 - MHC BRIDGING SYSTEM FOR DETECTING CTL-MEDIATED LYSIS OF ANTIGEN PRESENTING CELLS [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 11.06.2010 Database last updated on 03.09.2024
Most recent event Tooltip	11.06.2010	Application deemed to be withdrawn	published on 14.07.2010 [2010/28]
Applicant(s)	For all designated states Beckman Coulter, Inc. 250 S. Kraemer Boulevard Brea, CA 92821 / US
	[N/P]
Former [2010/26]	For all designated states Beckman Coulter, Inc. 250 S. Kraemer Boulevard Brea, 92821 CA / US
Former [2007/13]	For all designated states Beckman Coulter, Inc. 4300 N. Harbor Boulevard Fullerton, CA 92834 / US
Inventor(s)	01 / NUGENT, C. Thomas, IV 5301 Lodi Street San Diego, CA 92117 / US
	02 / KUMAR, Abhay 12638 Salmon River Road San Diego, CA 92129 / US
	03 / KUUS-REICHEL, Kristine 5047 Litchfield Road San Diego, CA 92116 / US
	[2007/13]
Representative(s)	Cornish, Kristina Victoria Joy, et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL / GB
	[N/P]
Former [2007/13]	Cornish, Kristina Victoria Joy, et al Kilburn & Strode, 20 Red Lion Street London WC1R 4PJ / GB
Application number, filing date	05745499.3	05.05.2005
	[2007/13]
	WO2005US15637
Priority number, date	US20040568900P	07.05.2004 Original published format: US 568900 P
	[2007/13]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2005111624
	Date:	24.11.2005
	Language:	EN
	[2005/47]
	Type:	A2 Application without search report
	No.:	EP1766393
	Date:	28.03.2007
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 24.11.2005 takes the place of the publication of the European patent application.
	[2007/13]
Search report(s)	International search report - published on:	US	12.01.2006
	(Supplementary) European search report - dispatched on:	EP	21.05.2008
Classification	IPC:	G01N33/53, G01N33/567, G01N33/574, C07K16/46, A61K39/395	[2007/13]
	CPC:	G01N33/502 (EP,US); G01N33/5011 (EP,US); G01N33/505 (EP,US); G01N33/57492 (EP,US); G01N2333/70539 (EP,US)
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR [2007/13]
Extension states	AL	Not yet paid
	BA	Not yet paid
	HR	Not yet paid
	LV	Not yet paid
	MK	Not yet paid
	YU	Not yet paid
Title	German:	MHC-BRÜCKENSYSTEM ZUM NACHWEIS DER CTL-VERMITTELTEN LYSE ANTIGENPRÄSENTIERENDER ZELLEN	[2007/13]
	English:	MHC BRIDGING SYSTEM FOR DETECTING CTL-MEDIATED LYSIS OF ANTIGEN PRESENTING CELLS	[2007/13]
	French:	SYSTÈME DE FORMATION DE PONT DE COMPLEXES MAJEURS D'HISTOCOMPATIBILITÉ POUR DÉTECTER UNE LYSE MÉDIÉE PAR LES LYMPHOCYTES T DE CELLULES PRÉSENTANT DES ANTIGÈNES	[2009/40]
	Former [2007/13]	SYSTÈME DE FORMATION DE PONT DE COMPLEXES D'HISTOCOMPATIBILITÉ PRINCIPALE POUR DÉTECTER UNE LYSE MÉDIÉE PAR LES LYMPHOCYTES T DE CELLULES PRÉSENTANT DES ANTIGÈNES
Entry into regional phase	07.12.2006	National basic fee paid
	07.12.2006	Search fee paid
	07.12.2006	Designation fee(s) paid
	07.12.2006	Examination fee paid
Examination procedure	07.12.2006	Examination requested [2007/15]
	11.12.2006	Amendment by applicant (claims and/or description)
	09.09.2008	Despatch of a communication from the examining division (Time limit: M06)
	17.03.2009	Reply to a communication from the examining division
	10.09.2009	Communication of intention to grant the patent
	21.01.2010	Application deemed to be withdrawn, date of legal effect [2010/28]
	26.02.2010	Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2010/28]
Fees paid	Renewal fee
	30.05.2007	Renewal fee patent year 03
	28.05.2008	Renewal fee patent year 04
	27.05.2009	Renewal fee patent year 05
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[A]WO9928748 (ISIS INNOVATION [GB], et al) [A] 1-25 * the whole document *;
		[A]WO9950637 (LUDWIG INST CANCER RES [US], et al) [A] 2,16-25 * example 49 *;
		[Y]US2002146746 (NIXON DOUGLAS [US], et al) [Y] 15-17 * paragraphs [0012] , [0036] - [0040] - [0045] , [0055] - [0068] - [0078] - [0081] * * example 1 *;
		[XY]US2003044415 (SAVAGE PHILIP MICHAEL [GB]) [X] 8-14,22-25 * paragraphs [0007] - [0029] - [0052] , [0074] - [0084] * * examples 1-3 * * figures 1,3 * * claims 1-19 * * idem * [Y] 1-7,15-17;
		[DX] - ROBERT B ET AL, "ANTIBODY-CONJUGATED MHC CLASS I TETRAMERS CAN TARGET TUMOR CELLS FOR SPECIFIC LYSIS BY T LYMPHOCYTES", EUROPEAN JOURNAL OF IMMUNOLOGY, WEINHEIM, DE, (200011), vol. 30, no. 11, ISSN 0014-2980, pages 3165 - 3170, XP001021944 [DX] 8-11,13,14 * paragraphs [02.3] , [04.3] , [04.5] * * figure 3 * DOI: http://dx.doi.org/10.1002/1521-4141(200011)30:11<3165::AID-IMMU3165>3.0.CO;2-R
		[Y] - PASQUIER DU R A ET AL, "LOW FREQUENCY OF CYTOTOXIC T LYMPHOCYTES AGAINST THE NOVEL HLA-A0201-RESTRICTED JC VIRUS EPITOPE VP1P36 IN PATIENTS WITH PROVEN OR POSSIBLE PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, (200311), vol. 77, no. 22, ISSN 0022-538X, pages 11918 - 11926, XP001181758 [Y] 1-7 abstract * * page 11919 - page 11920, paragraph "Functional lysis assay" * * page 11921 - page 11922, paragraph "Characterization of the HLA-A0201-restricted epitope JCV VP1p36" DOI: http://dx.doi.org/10.1128/JVI.77.22.11918-11926.2003
		[A] - MALLET-DESIGNE VALÉRIE I ET AL, "Detection of low-avidity CD4+ T cells using recombinant artificial APC: following the antiovalbumin immune response.", JOURNAL OF IMMUNOLOGY (BALTIMORE, MD. : 1950) 1 JAN 2003, (20030101), vol. 170, no. 1, ISSN 0022-1767, pages 123 - 131, XP002477831 [A] 1-25 * the whole document *
		[A] - HERMANS I F ET AL, "The VITAL assay: a versatile fluorometric technique for assessing CTL- and NKT-mediated cytotoxicity against multiple targets in vitro and in vivo", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, (20040201), vol. 285, no. 1, ISSN 0022-1759, pages 25 - 40, XP004489663 [A] 1-25 * the whole document * DOI: http://dx.doi.org/10.1016/j.jim.2003.10.017
	International search	[Y]US2002006903 (SCHNECK JONATHAN [US], et al);
		[X]US2003044415 (SAVAGE PHILIP MICHAEL [GB]);
		[Y] - CONSTANTIN ET AL, "Major Histocompatibility Complex (MHC) Tetramer Technology: An Evaluation.", BIOLOGICAL RESEARCH FOR NURSING., (200210), vol. 4, no. 2, pages 115 - 127, XP008056732 DOI: http://dx.doi.org/10.1177/1099800402238332
	Examination	- ALTMAN J; ET AL, "Phenotypic analysis of antigen-specific T lymphocytes", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, WASHINGTON, DC, (19961004), vol. 274, no. 5284, ISSN 0036-8075, pages 94 - 96, XP002135711 DOI: http://dx.doi.org/10.1126/science.274.5284.94
	by applicant	US5635363
		US2003044415
		- LECHNER, R ET AL., J. EXP. MED., (2000), vol. 191, pages 1499 - 1512
		- PASQUIER ET AL., JOURNAL OF VIROLOGY, (2003), vol. 77, pages 11918 - 11926
		- ALTMAN ET AL., SCIENCE, (1996), vol. 274, pages 94 - 96
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