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Extract from the Register of European Patents

EP About this file: EP1745024

EP1745024 - 1-ARYL-4-SUBSTITUTED ISOQUINOLINES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  01.03.2013
Database last updated on 01.10.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
Novartis International Pharmaceutical Ltd.
131 Front Street
Hamilton / BM
[2011/12]
Former [2007/04]For all designated states
NEUROGEN CORPORATION
35 N.E. Industrial Road
Branford, CT 06405 / US
Inventor(s)01 / LEE, Kyungae
259 Wiswall Road
Newton, MA 02459 / US
02 / YUAN, Jun
40 Spruce Hill Drive
Guilford, CT 06437 / US
03 / MAYNARD, George, D.
27 Glenwood Road
Clinton, CT 06413 / US
04 / HUTCHISON, Alan
27 Allison Drive
Madison, CT 06443 / US
05 / MITCHELL, Scott
13 Morris Road
East Haven, CT 06513 / US
 [2007/19]
Former [2007/04]01 / LEE, Kyungae
259 Wiswall Road
Newton, MA 02459 / US
02 / YUAN, Jun
40 Spruce Hill Drive
Guilford, CT 06437 / US
03 / MAYNARD, George, D.
27 Glenwood Road
Clinton, CT 06413 / US
04 / HUTCHISON, Alan
235 Neck Road
Madison, CT 06443 / US
05 / MITCHELL, Scott
13 Morris Road
East Haven, CT 06513 / US
Representative(s)Forstmeyer, Dietmar, et al
Boeters & Lieck
Oberanger 32
80331 München / DE
[N/P]
Former [2008/35]Forstmeyer, Dietmar, et al
BOETERS & LIECK Oberanger 32
80331 München / DE
Former [2007/04]Forstmeyer, Dietmar, et al
BOETERS & LIECK Oberanger 32
80331 München / DE
Application number, filing date05747952.906.05.2005
[2007/04]
WO2005US15959
Priority number, dateUS20040569182P08.05.2004         Original published format: US 569182 P
[2007/04]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2005110991
Date:24.11.2005
Language:EN
[2005/47]
Type: A1 Application with search report 
No.:EP1745024
Date:24.01.2007
Language:EN
The application published by WIPO in one of the EPO official languages on 24.11.2005 takes the place of the publication of the European patent application.
[2007/04]
Type: B1 Patent specification 
No.:EP1745024
Date:25.04.2012
Language:EN
[2012/17]
Search report(s)International search report - published on:US24.11.2005
(Supplementary) European search report - dispatched on:EP07.12.2007
ClassificationIPC:A61K31/47, A61P29/00, C07D217/02
[2007/52]
CPC:
C07D405/12 (EP,US); A61K31/47 (EP,US); A61P11/00 (EP);
A61P11/06 (EP); A61P17/06 (EP); A61P19/02 (EP);
A61P29/00 (EP); A61P43/00 (EP); A61P9/00 (EP);
A61P9/10 (EP); C07D217/14 (EP,US); C07D217/16 (EP,US);
C07D217/22 (EP,US); C07D401/04 (EP,US); C07D401/06 (EP,US);
C07D401/14 (EP,US); C07D413/14 (EP,US) (-)
Former IPC [2007/04]C07D217/02, A61K31/47
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2007/04]
TitleGerman:1-ARYL-4-SUBSTITUIERTE ISOCHINOLINE[2011/47]
English:1-ARYL-4-SUBSTITUTED ISOQUINOLINES[2007/04]
French:ISOQUINOLINES 1-ARYL-4-SUBSTITUEES[2007/04]
Former [2007/04]1-ARYL-4-SUBSTITUIERTES ISOCHINOLIN
Entry into regional phase19.10.2006National basic fee paid 
19.10.2006Search fee paid 
07.12.2006Designation fee(s) paid 
07.12.2006Examination fee paid 
Examination procedure07.12.2006Examination requested  [2007/04]
24.01.2007Amendment by applicant (claims and/or description)
03.02.2009Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time
15.06.2009Despatch of a communication from the examining division (Time limit: M06)
24.12.2009Reply to a communication from the examining division
15.02.2010Despatch of a communication from the examining division (Time limit: M04)
21.06.2010Reply to a communication from the examining division
08.09.2010Despatch of a communication from the examining division (Time limit: M04)
05.10.2010Reply to a communication from the examining division
13.01.2011Despatch of a communication from the examining division (Time limit: M04)
13.05.2011Reply to a communication from the examining division
28.10.2011Communication of intention to grant the patent
16.02.2012Fee for grant paid
16.02.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.06.2009
Opposition(s)28.01.2013No opposition filed within time limit [2013/14]
Fees paidRenewal fee
31.05.2007Renewal fee patent year 03
08.04.2009Renewal fee patent year 04
27.05.2009Renewal fee patent year 05
25.05.2010Renewal fee patent year 06
25.05.2011Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
31.05.200804   M06   Fee paid on   08.04.2009
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU06.05.2005
AT25.04.2012
BE25.04.2012
CY25.04.2012
CZ25.04.2012
DK25.04.2012
EE25.04.2012
FI25.04.2012
LT25.04.2012
NL25.04.2012
PL25.04.2012
RO25.04.2012
SE25.04.2012
SI25.04.2012
SK25.04.2012
TR25.04.2012
IE06.05.2012
LU06.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
BG25.07.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
[2014/34]
Former [2014/27]AT25.04.2012
BE25.04.2012
CY25.04.2012
CZ25.04.2012
DK25.04.2012
EE25.04.2012
FI25.04.2012
LT25.04.2012
NL25.04.2012
PL25.04.2012
RO25.04.2012
SE25.04.2012
SI25.04.2012
SK25.04.2012
TR25.04.2012
IE06.05.2012
LU06.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
BG25.07.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2014/21]AT25.04.2012
BE25.04.2012
CY25.04.2012
CZ25.04.2012
DK25.04.2012
EE25.04.2012
FI25.04.2012
LT25.04.2012
NL25.04.2012
PL25.04.2012
RO25.04.2012
SE25.04.2012
SI25.04.2012
SK25.04.2012
TR25.04.2012
IE06.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
BG25.07.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2013/34]AT25.04.2012
BE25.04.2012
CY25.04.2012
CZ25.04.2012
DK25.04.2012
EE25.04.2012
FI25.04.2012
LT25.04.2012
NL25.04.2012
PL25.04.2012
RO25.04.2012
SE25.04.2012
SI25.04.2012
SK25.04.2012
IE06.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
BG25.07.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2013/20]AT25.04.2012
BE25.04.2012
CY25.04.2012
CZ25.04.2012
DK25.04.2012
EE25.04.2012
FI25.04.2012
LT25.04.2012
NL25.04.2012
PL25.04.2012
RO25.04.2012
SE25.04.2012
SI25.04.2012
SK25.04.2012
IE06.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2013/10]AT25.04.2012
BE25.04.2012
CY25.04.2012
CZ25.04.2012
DK25.04.2012
EE25.04.2012
FI25.04.2012
LT25.04.2012
NL25.04.2012
PL25.04.2012
RO25.04.2012
SE25.04.2012
SI25.04.2012
SK25.04.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2013/09]AT25.04.2012
BE25.04.2012
CY25.04.2012
DK25.04.2012
EE25.04.2012
FI25.04.2012
LT25.04.2012
NL25.04.2012
PL25.04.2012
SE25.04.2012
SI25.04.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2013/08]AT25.04.2012
BE25.04.2012
CY25.04.2012
DK25.04.2012
FI25.04.2012
LT25.04.2012
NL25.04.2012
PL25.04.2012
SE25.04.2012
SI25.04.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2013/07]AT25.04.2012
BE25.04.2012
CY25.04.2012
FI25.04.2012
LT25.04.2012
PL25.04.2012
SE25.04.2012
SI25.04.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2013/04]BE25.04.2012
CY25.04.2012
FI25.04.2012
LT25.04.2012
PL25.04.2012
SE25.04.2012
SI25.04.2012
MC31.05.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2013/03]CY25.04.2012
FI25.04.2012
LT25.04.2012
PL25.04.2012
SE25.04.2012
SI25.04.2012
MC31.05.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2013/01]CY25.04.2012
FI25.04.2012
LT25.04.2012
PL25.04.2012
SE25.04.2012
SI25.04.2012
GR26.07.2012
IS25.08.2012
PT27.08.2012
Former [2012/51]CY25.04.2012
FI25.04.2012
LT25.04.2012
PL25.04.2012
SE25.04.2012
SI25.04.2012
GR26.07.2012
IS25.08.2012
Former [2012/50]CY25.04.2012
FI25.04.2012
LT25.04.2012
PL25.04.2012
SE25.04.2012
GR26.07.2012
IS25.08.2012
Former [2012/49]CY25.04.2012
FI25.04.2012
LT25.04.2012
PL25.04.2012
SE25.04.2012
IS25.08.2012
Former [2012/48]FI25.04.2012
LT25.04.2012
SE25.04.2012
Former [2012/47]LT25.04.2012
Documents cited:Search[X]WO9827066  (NEUROGEN CORP [US], et al) [X] 1,41,42 * example -; claims 1,9-21 *;
 [X]WO03028730  (NOVARTIS AG [CH], et al) [X] 1,2,41 * example -; claim - *;
 [X]  - S. TANDEL ET AL., "convenient synthesis of 1-substituted derivatives of 4-(1-propenyl)- and 4-allyl-3-aminoisoquinolines.", HETEROCYCLES., NLELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM., (2000), vol. 53, no. 5, pages 1183 - 1191, XP002458881 [X] 1,2 * page 1183 - page 1190 *
International search[X]US4260611  (BARTMANN WILHELM, et al);
 [X]US4282223  (BARTMANN WILHELM, et al);
 [X]  - HENRY R. ET AL., "Reactions of Epimeric 2,2'-diacetyl-1,1'2,2'-tetrahydro-1,1'-biisoquinolines.", ORG. CHEM., (1972), vol. 37, no. 21, pages 3206 - 3209, XP002990751

DOI:   http://dx.doi.org/10.1021/jo00986a002
by applicantWO03028730
 WO03082828
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.