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Extract from the Register of European Patents

EP About this file: EP1740192

EP1740192 - CYCLIC DINUCLEOTIDE FOR STIMULATING THE IMMUNE OF INFLAMMATORY RESPONSE [Right-click to bookmark this link]
Former [2007/02]METHOD FOR STIMULATING THE IMMUNE, INFLAMMATORY OR NEUROPROTECTIVE RESPONSE
[2011/50]
StatusNo opposition filed within time limit
Status updated on  19.04.2013
Database last updated on 24.08.2024
Most recent event   Tooltip17.07.2015Lapse of the patent in a contracting state
New state(s): HU		published on 19.08.2015  [2015/34]
Applicant(s)For all designated states
Karaolis, David K. R.
Oakhaven
Baltimore MD 21210-2227 / US
[2007/02]
Inventor(s)01 / see applicant
...
 [2007/02]
Representative(s)Webber, Philip Michael
Dehns
St Bride's House
10 Salisbury Square
London
EC4Y 8JD / GB
[N/P]
Former [2012/24]Webber, Philip Michael
Dehns St Bride's House 10 Salisbury Square London
EC4Y 8JD / GB
Former [2007/02]Webber, Philip Michael
Frank B. Dehn & Co. St Bride's House 10 Salisbury Square
London EC4Y 8JD / GB
Application number, filing date05753223.615.03.2005
[2007/02]
WO2005US08447
Priority number, dateUS20040552721P15.03.2004         Original published format: US 552721 P
US20040563692P20.04.2004         Original published format: US 563692 P
[2007/02]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2005087238
Date:22.09.2005
Language:EN
[2005/38]
Type: A2 Application without search report 
No.:EP1740192
Date:10.01.2007
Language:EN
The application published by WIPO in one of the EPO official languages on 22.09.2005 takes the place of the publication of the European patent application.
[2007/02]
Type: B1 Patent specification 
No.:EP1740192
Date:13.06.2012
Language:EN
[2012/24]
Search report(s)International search report - published on:EP09.03.2006
ClassificationIPC:A61K31/7084, A61P25/00, A61P25/16, A61P25/28, A61P37/04
[2007/02]
CPC:
A61K31/7084 (EP,US); A61K31/7076 (EP,US); A61K39/39 (EP,US);
A61P19/02 (EP); A61P21/00 (EP); A61P25/00 (EP);
A61P25/16 (EP); A61P25/28 (EP); A61P27/06 (EP);
A61P31/00 (EP); A61P35/00 (EP); A61P37/02 (EP);
A61P37/04 (EP); A61P37/08 (EP); A61P9/10 (EP);
A61K2039/55511 (EP,US); A61K2039/55561 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2007/02]
TitleGerman:ZYKLISCHE DINUCLEOTIDE ZUR STIMULIERUNG VON IMMUN- ODER ENTZÜNDUNGSREAKTIONENE[2011/50]
English:CYCLIC DINUCLEOTIDE FOR STIMULATING THE IMMUNE OF INFLAMMATORY RESPONSE[2011/50]
French:DINUCLEOTIDES CYCLIQUES POUR STIMULER LA REPONSE INMMUNITAIRE OU INFLAMMATOIRE[2011/50]
Former [2007/02]VERFAHREN ZUR STIMULIERUNG VON IMMUN-, ENTZÜNDUNGS- ODER NERVENSCHUTZREAKTIONEN
Former [2007/02]METHOD FOR STIMULATING THE IMMUNE, INFLAMMATORY OR NEUROPROTECTIVE RESPONSE
Former [2007/02]TECHNIQUE DE STIMULATION DE REPONSE IMMUNE, INFLAMMATOIRE OU NEUROPROSPECTIVE
Entry into regional phase13.10.2006National basic fee paid 
13.10.2006Designation fee(s) paid 
13.10.2006Examination fee paid 
Examination procedure13.10.2006Amendment by applicant (claims and/or description)
13.10.2006Examination requested  [2007/02]
26.09.2008Despatch of a communication from the examining division (Time limit: M06)
06.04.2009Reply to a communication from the examining division
15.01.2010Despatch of a communication from the examining division (Time limit: M04)
25.05.2010Reply to a communication from the examining division
28.11.2011Communication of intention to grant the patent
27.03.2012Fee for grant paid
27.03.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  26.09.2008
Opposition(s)14.03.2013No opposition filed within time limit [2013/21]
Fees paidRenewal fee
26.04.2007Renewal fee patent year 03
31.03.2008Renewal fee patent year 04
26.03.2009Renewal fee patent year 05
24.03.2010Renewal fee patent year 06
28.03.2011Renewal fee patent year 07
26.03.2012Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.03.200703   M06   Fee paid on   26.04.2007
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.03.2005
AT13.06.2012
BE13.06.2012
CY13.06.2012
CZ13.06.2012
DK13.06.2012
EE13.06.2012
FI13.06.2012
IT13.06.2012
LT13.06.2012
NL13.06.2012
PL13.06.2012
RO13.06.2012
SE13.06.2012
SI13.06.2012
SK13.06.2012
TR13.06.2012
BG13.09.2012
GR14.09.2012
ES24.09.2012
IS13.10.2012
PT15.10.2012
[2015/34]
Former [2015/32]AT13.06.2012
BE13.06.2012
CY13.06.2012
CZ13.06.2012
DK13.06.2012
EE13.06.2012
FI13.06.2012
IT13.06.2012
LT13.06.2012
NL13.06.2012
PL13.06.2012
RO13.06.2012
SE13.06.2012
SI13.06.2012
SK13.06.2012
TR13.06.2012
BG13.09.2012
GR14.09.2012
ES24.09.2012
IS13.10.2012
PT15.10.2012
Former [2013/34]AT13.06.2012
BE13.06.2012
CY13.06.2012
CZ13.06.2012
DK13.06.2012
EE13.06.2012
FI13.06.2012
IT13.06.2012
LT13.06.2012
NL13.06.2012
PL13.06.2012
RO13.06.2012
SE13.06.2012
SI13.06.2012
SK13.06.2012
BG13.09.2012
GR14.09.2012
ES24.09.2012
IS13.10.2012
PT15.10.2012
Former [2013/22]AT13.06.2012
BE13.06.2012
CY13.06.2012
CZ13.06.2012
DK13.06.2012
EE13.06.2012
FI13.06.2012
IT13.06.2012
LT13.06.2012
NL13.06.2012
PL13.06.2012
RO13.06.2012
SE13.06.2012
SI13.06.2012
SK13.06.2012
GR14.09.2012
ES24.09.2012
IS13.10.2012
PT15.10.2012
Former [2013/21]AT13.06.2012
BE13.06.2012
CY13.06.2012
CZ13.06.2012
DK13.06.2012
EE13.06.2012
FI13.06.2012
IT13.06.2012
LT13.06.2012
NL13.06.2012
PL13.06.2012
RO13.06.2012
SE13.06.2012
SI13.06.2012
SK13.06.2012
GR14.09.2012
IS13.10.2012
PT15.10.2012
Former [2013/15]AT13.06.2012
BE13.06.2012
CY13.06.2012
CZ13.06.2012
EE13.06.2012
FI13.06.2012
IT13.06.2012
LT13.06.2012
NL13.06.2012
PL13.06.2012
RO13.06.2012
SE13.06.2012
SI13.06.2012
SK13.06.2012
GR14.09.2012
IS13.10.2012
PT15.10.2012
Former [2013/13]AT13.06.2012
BE13.06.2012
CY13.06.2012
CZ13.06.2012
EE13.06.2012
FI13.06.2012
IT13.06.2012
LT13.06.2012
PL13.06.2012
RO13.06.2012
SE13.06.2012
SI13.06.2012
SK13.06.2012
GR14.09.2012
IS13.10.2012
PT15.10.2012
Former [2013/11]AT13.06.2012
BE13.06.2012
CY13.06.2012
CZ13.06.2012
EE13.06.2012
FI13.06.2012
IT13.06.2012
LT13.06.2012
PL13.06.2012
RO13.06.2012
SE13.06.2012
SI13.06.2012
SK13.06.2012
GR14.09.2012
IS13.10.2012
Former [2013/10]AT13.06.2012
BE13.06.2012
CY13.06.2012
CZ13.06.2012
EE13.06.2012
FI13.06.2012
LT13.06.2012
RO13.06.2012
SE13.06.2012
SI13.06.2012
SK13.06.2012
GR14.09.2012
IS13.10.2012
Former [2013/09]AT13.06.2012
BE13.06.2012
CY13.06.2012
EE13.06.2012
FI13.06.2012
LT13.06.2012
SE13.06.2012
SI13.06.2012
GR14.09.2012
Former [2013/07]AT13.06.2012
BE13.06.2012
CY13.06.2012
FI13.06.2012
LT13.06.2012
SE13.06.2012
SI13.06.2012
GR14.09.2012
Former [2012/51]CY13.06.2012
FI13.06.2012
LT13.06.2012
SE13.06.2012
SI13.06.2012
GR14.09.2012
Former [2012/50]CY13.06.2012
FI13.06.2012
LT13.06.2012
SE13.06.2012
GR14.09.2012
Former [2012/49]CY13.06.2012
FI13.06.2012
LT13.06.2012
SE13.06.2012
Former [2012/48]FI13.06.2012
LT13.06.2012
SE13.06.2012
Former [2012/47]LT13.06.2012
Cited inInternational search[E]WO2005030186  (UNIV MARYLAND [US], et al) [E] 1-13,22,24-28,33 * the whole document *;
 [PX]  - TISCHLER ANNA D ET AL, "Cyclic diguanylate (c-di-GMP) regulates Vibrio cholerae biofilm formation", MOLECULAR MICROBIOLOGY, (200408), vol. 53, no. 3, ISSN 0950-382X, pages 857 - 869, XP009052833 [PX] 1-14,22-29,33 * abstract *

DOI:   http://dx.doi.org/10.1111/j.1365-2958.2004.04155.x
 [PX]  - KARAOLIS DAVID K R ET AL, "c-di-GMP (3'-5'-cyclic diguanylic acid) inhibits Staphylococcus aureus cell-cell interactions and biofilm formation", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, (200503), vol. 49, no. 3, ISSN 0066-4804, pages 1029 - 1038, XP009052927 [PX] 1-14,22-29,33 * abstract *

DOI:   http://dx.doi.org/10.1128/AAC.49.3.1029-1038.2005
 [A]  - STEINBERGER O ET AL, "Elevated expression of the CD4 receptor and cell cycle arrest are induced in Jurkat cells by treatment with the novel cyclic dinucleotide 3',5'-cyclic diguanylic acid", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (19990205), vol. 444, no. 1, ISSN 0014-5793, pages 125 - 129, XP004259225 [A] 1-14,22-29,33 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0014-5793(99)00036-8
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.