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Extract from the Register of European Patents

EP About this file: EP1756108

EP1756108 - Azaindoles useful as inhibitors of ROCK and other protein kinases [Right-click to bookmark this link]
Former [2007/09]AZAINDOLES USEFUL AS INHIBITORS OF ROCK AND OTHER PROTEIN KINASES
[2012/17]
StatusThe application is deemed to be withdrawn
Status updated on  18.01.2013
Database last updated on 05.10.2024
Most recent event   Tooltip18.01.2013Application deemed to be withdrawnpublished on 20.02.2013  [2013/08]
Applicant(s)For all designated states
VERTEX PHARMACEUTICALS INCORPORATED
130 Waverly Street
Cambridge, MA 02139 / US
[2007/09]
Inventor(s)01 / GREEN, Jeremy
125 Lincoln Wood Road
Waltham, MA 2451 / US
02 / MILLER, Andrew
Cherry Cottage, Chilton Road
Upton, Oxfordshire OX11 9JL / GB
03 / JIMENEZ, Juan-Miguel
39 Alexander Close
Abingdon, Oxfordshire OX14 1XA / GB
04 / MARHEFKA, Craig
11411 Eunice Ct.
White Marsh, Maryland 21162 / US
05 / CAO, Jingrong
45 Madison Avenue
Newton, MA 02165 / US
06 / COURT, John, J.
27 Ernies Drive
Littleton, MA 01460 / US
07 / BANDARAGE, Upul, K.
11 Bates Road
Lexington, MA 02421 / US
08 / GAO, Huai
25 Sunnyside Lane
Lincoln, MA 01773 / US
09 / NANTHAKUMAR, Suganthini
253 Spiers Road
Newton, MA 02459 / US
 [2007/09]
Representative(s)Cohausz & Florack
Patent- & Rechtsanwälte
Partnerschaftsgesellschaft mbB
Bleichstrasse 14
40211 Düsseldorf / DE
[N/P]
Former [2008/31]Cohausz & Florack
Patent- und Rechtsanwälte Bleichstrasse 14
40211 Düsseldorf / DE
Former [2007/09]Cohausz & Florack
Patent- und Rechtsanwälte Bleichstrasse 14
40211 Düsseldorf / DE
Application number, filing date05767612.404.04.2005
[2007/09]
WO2005US11358
Priority number, dateUS20040559041P02.04.2004         Original published format: US 559041 P
[2007/09]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2005103050
Date:03.11.2005
Language:EN
[2005/44]
Type: A2 Application without search report 
No.:EP1756108
Date:28.02.2007
Language:EN
The application published by WIPO in one of the EPO official languages on 03.11.2005 takes the place of the publication of the European patent application.
[2007/09]
Search report(s)International search report - published on:EP05.10.2006
ClassificationIPC:C07D471/04, A61K31/437, A61P37/08, A61P29/00
[2007/09]
CPC:
C07D471/04 (EP,KR,US); A61K31/4353 (KR); A61P1/04 (EP);
A61P1/16 (EP); A61P1/18 (EP); A61P11/00 (EP);
A61P11/02 (EP); A61P11/06 (EP); A61P13/08 (EP);
A61P13/12 (EP); A61P15/06 (EP); A61P15/10 (EP);
A61P17/00 (EP); A61P17/04 (EP); A61P17/06 (EP);
A61P17/08 (EP); A61P17/14 (EP); A61P19/00 (EP);
A61P19/02 (EP); A61P19/08 (EP); A61P19/10 (EP);
A61P21/00 (EP); A61P21/04 (EP); A61P25/00 (EP);
A61P25/14 (EP); A61P25/16 (EP); A61P25/18 (EP);
A61P25/28 (EP); A61P27/02 (EP); A61P27/06 (EP);
A61P29/00 (EP); A61P3/10 (EP); A61P31/08 (EP);
A61P31/12 (EP); A61P31/16 (EP); A61P31/18 (EP);
A61P35/00 (EP); A61P37/00 (EP); A61P37/02 (EP);
A61P37/04 (EP); A61P37/06 (EP); A61P37/08 (EP);
A61P43/00 (EP); A61P5/16 (EP); A61P7/00 (EP);
A61P7/06 (EP); A61P9/00 (EP); A61P9/08 (EP);
A61P9/10 (EP); A61P9/12 (EP); A61P9/14 (EP) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2007/09]
Extension statesAL11.10.2006
BA11.10.2006
HR11.10.2006
LV11.10.2006
MK11.10.2006
YU11.10.2006
TitleGerman:Azaindole zur Verwendung als Inhibitoren von ROCK und anderen Proteinkinasen[2012/17]
English:Azaindoles useful as inhibitors of ROCK and other protein kinases[2012/17]
French:Azaindoles utiles en tant qu'inhibiteurs de la protéine kinase de la famille ROCK et d'autres protéines kinases[2012/17]
Former [2007/09]ALS INHIBITOREN VON ROCK UND ANDEREN PROTEINKINASEN NÜTZLICHE AZAINDOLE
Former [2007/09]AZAINDOLES USEFUL AS INHIBITORS OF ROCK AND OTHER PROTEIN KINASES
Former [2007/09]AZAINDOLES UTILES EN TANT QU'INHIBITEURS DE LA PROTEINE SERINE/THREONINE KINASE SUPERHELICE DE LA FAMILLE RHO (ROCK) ET D'AUTRES PROTEINES KINASES
Entry into regional phase11.10.2006National basic fee paid 
11.10.2006Designation fee(s) paid 
11.10.2006Examination fee paid 
Examination procedure11.10.2006Examination requested  [2007/09]
19.08.2008Despatch of a communication from the examining division (Time limit: M04)
29.12.2008Reply to a communication from the examining division
28.09.2009Despatch of a communication from the examining division (Time limit: M06)
01.04.2010Reply to a communication from the examining division
19.04.2012Communication of intention to grant the patent
30.08.2012Application deemed to be withdrawn, date of legal effect  [2013/08]
08.10.2012Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2013/08]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  19.08.2008
Fees paidRenewal fee
27.04.2007Renewal fee patent year 03
25.04.2008Renewal fee patent year 04
29.04.2009Renewal fee patent year 05
26.04.2010Renewal fee patent year 06
25.04.2011Renewal fee patent year 07
25.04.2012Renewal fee patent year 08
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Cited inInternational search[AD]WO9965897  (CHIRON CORP [US], et al) [AD] 1,41,43 * claims 1,73,82,84 *;
 [A]WO03028724  (SMITHKLINE BEECHAM CORP [US], et al) [A] 1,41,45 * claims 1,7-9 *;
 [A]WO03082869  (EISAI LONDON RES LAB LIMTED [GB], et al) [A] 1,41,45 * claims 1,7,16-38 *;
 [A]WO2004016610  (ASTRAZENECA AB [SE], et al) [A] 1,41,45 * claims 1,6-9 *;
 [AP]WO2004078756  (EISAI LONDON RES LAB LTD [GB], et al) [AP] 1-52* claims 1-5,7,9,84-111 *
by applicant   - HANKS, S.K.; HUNTER, T., FASEB J, (1995), vol. 9, pages 576 - 596
    - KAWAKAMI ET AL., JOURNAL OF IMMUNOLOGY, (1995), pages 3556 - 3562
    - KAWAKAMI ET AL., JOURNAL OF LEUKOCYTE BIOLOGY, vol. 65, pages 286 - 290
    - MUKHOPADHYAY ET AL., JOURNAL OF IMMUNOLOGY, (2002), vol. 168, pages 2914 - 2921
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.