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EP1859041
European procedure
Extract from the Register of European Patents
EP About this file: EP1859041
| EP1859041 - APROTININ POLYPEPTIDES FOR TRANSPORTING A COMPOUND ACROSS THE BLOOD-BRAIN BARRIER [Right-click to bookmark this link] | Status | Patent maintained as amended Status updated on 17.10.2014 Database last updated on 14.03.2026 | Most recent event Tooltip | 14.06.2019 | Change - lapse in a contracting state State(s) deleted from list of lapses: TR | published on 17.07.2019 [2019/29] | Applicant(s) | For all designated states Angiochem Inc. 201 President Kennedy Avenue Suite PK-R220 Montréal, QC H2X 3Y7 / CA | [2012/12] |
| Former [2008/21] | For all designated states Angiochem Inc. 201 President Kennedy Avenue Suite PK-R210 Montréal, QC H2X 3Y7 / CA | ||
| Former [2007/48] | For all designated states Angiochem Inc. 141 President Kennedy Avenue Suite SB-5210 Montréal, Québec H2X 3Y7 / CA | Inventor(s) | 01 /
BÉLIVEAU, Richard 8 Cours du Fleuve Verdun, Québec H3E 1X1 / CA | 02 /
DEMEULE, Michel 343 Preston Drive Beaconsfield, Québec H9W 1Z2 / CA | 03 /
CHÉ, Christian 1455 St. Charles Ouest, appt 6 Longueuil, Québec J4K 1A7 / CA | 04 /
REGINA, Anthony 10610 Avenue de Lorimier Montréal, Québec H2B 2J3 / CA | [2012/12] |
| Former [2007/48] | 01 /
BELIVEAU, Richard 8 Cours du Fleuve Verdun, Québec H3E 1X1 / CA | ||
| 02 /
DEMEULE, Michel 343 Preston Beaconsfield, Québec H9W 1Z2 / CA | |||
| 03 /
CHE, Christian 7385 Avenue Chateaubriand Montréal, Québec H2R 2L7 / CA | |||
| 04 /
REGINA, Anthony 7385 Avenue Chateaubriand Montréal, Québec H2R 2L7 / CA | Representative(s) | Bösl, Raphael Konrad, et al Patentanwälte Isenbruck Bösl Hörschler PartG mbB Eastsite One Seckenheimer Landstraße 4 68163 Mannheim / DE | [N/P] |
| Former [2012/13] | Bösl, Raphael Konrad, et al Isenbruck Bösl Hörschler LLP Patentanwälte Prinzregentenstrasse 68 81675 München / DE | ||
| Former [2008/21] | Bösl, Raphael Konrad, et al Patentanwälte Isenbruck Bösl Hörschler Wichmann Huhn Prinzregentenstrasse 68 81675 München / DE | ||
| Former [2008/10] | Bösl, Raphael Konrad Patentanwälte Isenbruck Bösl Hörschler Wichmann Huhn Prinzregentenstrasse 68 81675 München / DE | ||
| Former [2007/48] | Gardner, Rebecca Katherine, et al Frank B. Dehn & Co. St Bride's House 10 Salisbury Square London EC4Y 8JD / GB | Application number, filing date | 05770546.9 | 21.07.2005 | [2007/48] | WO2005CA01158 | Priority number, date | US20050653928P | 18.02.2005 Original published format: US 653928 P | [2007/48] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2006086870 | Date: | 24.08.2006 | Language: | EN | [2006/34] | Type: | A1 Application with search report | No.: | EP1859041 | Date: | 28.11.2007 | Language: | EN | The application published by WIPO in one of the EPO official languages on 24.08.2006 takes the place of the publication of the European patent application. | [2007/48] | Type: | B1 Patent specification | No.: | EP1859041 | Date: | 28.03.2012 | Language: | EN | [2012/13] | Type: | B2 New European patent specification | No.: | EP1859041 | Date: | 19.11.2014 | Language: | EN | [2014/47] | Search report(s) | International search report - published on: | CA | 24.08.2006 | (Supplementary) European search report - dispatched on: | EP | 08.09.2008 | Classification | IPC: | C12N15/15, C07K14/81, A61K47/48, A61K47/42, A61K51/08, A61K49/14, A61P25/00 | [2007/48] | CPC: |
C07K14/8117 (EP,CN,RU,US);
C07K7/08 (RU);
A61K39/44 (RU,US);
A61K31/337 (EP,CN,RU,US);
A61K47/64 (EP,CN,US);
A61P25/00 (EP);
A61P25/08 (EP);
A61P25/10 (EP);
A61P25/12 (EP);
A61P25/14 (EP);
A61P25/16 (EP);
A61P25/18 (EP);
A61P25/28 (EP);
A61P3/04 (EP);
A61P35/00 (EP);
A61P35/04 (EP);
A61P43/00 (EP);
A61P9/10 (EP);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2007/48] | Extension states | AL | Not yet paid | BA | Not yet paid | HR | Not yet paid | MK | Not yet paid | YU | Not yet paid | Title | German: | APROTININPOLYPEPTIDE ZUM TRANSPORT EINER VERBINDUNG DURCH DIE BLUT-HIRN-SCHRANKE | [2007/48] | English: | APROTININ POLYPEPTIDES FOR TRANSPORTING A COMPOUND ACROSS THE BLOOD-BRAIN BARRIER | [2007/48] | French: | POLYPEPTIDES D'APROTININE POUR TRANSPORTER UN COMPOSÉ À TRAVERS UNE BARRIERE SANG-CERVEAU | [2007/48] | Entry into regional phase | 17.09.2007 | National basic fee paid | 17.09.2007 | Search fee paid | 17.09.2007 | Designation fee(s) paid | 17.09.2007 | Examination fee paid | Examination procedure | 18.12.2006 | Request for preliminary examination filed International Preliminary Examining Authority: CA | 17.09.2007 | Examination requested [2007/48] | 21.11.2007 | Amendment by applicant (claims and/or description) | 27.01.2009 | Despatch of a communication from the examining division (Time limit: M06) | 06.08.2009 | Reply to a communication from the examining division | 11.01.2010 | Despatch of a communication from the examining division (Time limit: M06) | 21.07.2010 | Reply to a communication from the examining division | 18.01.2011 | Despatch of a communication from the examining division (Time limit: M04) | 25.05.2011 | Reply to a communication from the examining division | 15.06.2011 | Despatch of a communication from the examining division (Time limit: M04) | 22.07.2011 | Reply to a communication from the examining division | 29.09.2011 | Communication of intention to grant the patent | 18.01.2012 | Observations by third parties | 08.02.2012 | Fee for grant paid | 08.02.2012 | Fee for publishing/printing paid | Divisional application(s) | EP11000946.1 / EP2360258 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 27.01.2009 | Opposition(s) | Opponent(s) | 01
24.12.2012
11.01.2013
ADMISSIBLE Small, Gary James Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB Opponent's representative Cockerton, Bruce Roger Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | [N/P] |
| Former [2013/07] | |||
| Opponent(s) | 01
24.12.2012
Small, Gary James Carpmaels & Ransford One Southampton Row London WC1B 5HA / GB Opponent's representative Cockerton, Bruce Roger Carpmaels & Ransford One Southampton Row London WC1B 5HA / GB | 05.02.2013 | Invitation to proprietor to file observations on the notice of opposition | 14.06.2013 | Reply of patent proprietor to notice(s) of opposition | 03.01.2014 | Despatch of a communication from the opposition division (Time limit: M02) | 28.01.2014 | Reply to a communication from the opposition division | 05.02.2014 | Cancellation of oral proceeding that was planned for 27.03.2014 | 18.02.2014 | Despatch of interlocutory decision in opposition | 28.02.2014 | Legal effect of interlocutory decision in opposition | 27.03.2014 | Date of oral proceedings | 02.07.2014 | Despatch of communication that the patent will be maintained as amended | 07.10.2014 | Fee for printing new specification paid | Fees paid | Renewal fee | 17.09.2007 | Renewal fee patent year 03 | 25.07.2008 | Renewal fee patent year 04 | 28.07.2009 | Renewal fee patent year 05 | 26.07.2010 | Renewal fee patent year 06 | 25.07.2011 | Renewal fee patent year 07 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | deleted | [2019/29] |
| Former [2014/25] | TR | 21.07.2012 | |
| Former [2012/40] | deleted | ||
| Former [2012/39] | LV | 28.03.2012 | Documents cited: | Search | [E] WO2007009229 (ANGIOCHEM INC et al.) [E] 1-8,21-34 * the whole document * | [A] WITT K A ET AL: "Peptide drug modifications to enhance bioavailability and blood-brain barrier permeability.", PEPTIDES DEC 2001, vol. 22, no. 12, December 2001 (2001-12-01), pages 2329 - 2343, XP002493438, ISSN: 0196-9781 [A] * page 2336, column 1, line 38 - line 41 * DOI: http://dx.doi.org/10.1016/S0196-9781(01)00537-X | Examination | ARPICCO S ET AL: "NEW COUPLING REAGENTS FOR THE PREPARATION OF DISULFIDE CROSS- LINKED CONJUGATES WITH INCREASED STABILITY", BIOCONJUGATE CHEMISTRY, ACS, WASHINGTON, DC, US, vol. 8, no. 3, 1 May 1997 (1997-05-01), pages 327 - 337, XP000689387, ISSN: 1043-1802, DOI: 10.1021/BC970025W [A] * page 2336, column 1, line 38 - line 41 * DOI: http://dx.doi.org/10.1021/bc970025w | SAITO G ET AL: "Drug delivery strategy utilizing conjugation via reversible disulfide linkages: Role and site of cellular reducing activities", ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER BV, AMSTERDAM, NL, vol. 55, no. 2, 10 February 2003 (2003-02-10), pages 199 - 215, XP002602054, ISSN: 0169-409X, DOI: 10.1016/S0169-409X(02)00179-5 DOI: http://dx.doi.org/10.1016/S0169-409X(02)00179-5 | EIGENBROT C ET AL: "X-ray structure of glial cell-derived neurotrophic factor at 1.9 A resolution and implications for receptor binding", NATURE STRUCTURAL BIOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 4, no. 6, 1 June 1997 (1997-06-01), pages 435 - 438, XP009030120, ISSN: 1072-8368, DOI: 10.1038/NSB0697-435 DOI: http://dx.doi.org/10.1038/nsb0697-435 | LEWIS M R ET AL: "MALEIMIDOCYSTEINEAMIDO-DOTA DERIVATIVES: NEW REAGENTS FOR RADIOMETAL CHELATE CONJUGATION TO ANTIBODY SULFHYDRYL GROUPS UNDERGO PH-DEPENDENT CLEAVAGE REACTIONS", BIOCONJUGATE CHEMISTRY, ACS, WASHINGTON, DC, US, vol. 9, no. 1, 1 January 1998 (1998-01-01), pages 72 - 86, XP002939365, ISSN: 1043-1802, DOI: 10.1021/BC970136V DOI: http://dx.doi.org/10.1021/bc970136v | by applicant | US5780265 | US5118668 | US5807980 | CA2004000011 | WO2004060403 | LUBERT STRYER: "Biochemistry", 1988, W.H. FREEMAN AND COMPANY | LACCABUE ET AL., CANCER, vol. 92, no. 12, 2001, pages 3085 - 92 | DAGENAIS ET AL., J. CEREB. BLOOD FLOW METAB., vol. 20, no. 2, 2000, pages 381 - 386 | SMITH, PHARM. BIOTECHNOL., vol. 8, 1996, pages 285 - 307 |