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Extract from the Register of European Patents

EP About this file: EP1699773

EP1699773 - PROCESSES FOR PREPARATION OF CRYSTALLINE MYCOPHENOLATE SODIUM [Right-click to bookmark this link]
Status	The application has been refused Status updated on 05.12.2008 Database last updated on 02.11.2024
Most recent event Tooltip	05.12.2008	Refusal of application	published on 07.01.2009 [2009/02]
Applicant(s)	For all designated states TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság Pallagi út 13 4042 Debrecen / HU
	[N/P]
Former [2006/40]	For all designated states TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság Pallagi ut 13 4042 Debrecen / HU
Former [2006/37]	For all designated states Ceva Gyogyszergyar R Szv Nytarsasag Pallagi 13 4042 Debrecen / HU
Inventor(s)	01 / MOLNAR, Sandor Derék u. 126. 1/3 H-4031 Debrecen / HU
	02 / SZABO, Csaba Tozser u. 1. H-4031 Debrecen / HU
	03 / TAMAS, Tivadar Szep utca 20 H-4034 Debrecen / HU
	04 / HAJKO, Janos Zold Sandor utca 20 4/17 H-4028 Debrecen / HU
	05 / KOVACSNE-MEZEI, Adrienne 252 Karoli Gaspar Street H-4032 Debrecen / HU
	06 / ARONHIME, Judith Rehov Harav Maor Iosef 5a 76217 Rehovot / IL
	[2007/22]
Former [2006/37]	01 / MOLNAR, Sandor Tocoskert ter 2, IX/71 H-4031 Debrecen / HU
	02 / SZABO, Csaba Tozser u. 1. H-4031 Debrecen / HU
	03 / TAMAS, Tivadar Budai Nagy Antal u. 37 H-4034 Debrecen / HU
	04 / HAJKO, Janos Zold Sandor utca 20 4/17 H-4028 Debrecen / HU
	05 / KOVACSNE-MEZEI, Adrienne 252 Karoli Gaspar Street H-4032 Debrecen / HU
	06 / ARONHIME, Judith Rehov Harav Maor Iosef 5a 76217 Rehovot / IL
Representative(s)	Wong, Kit Yee, et al D Young & Co LLP 120 Holborn London EC1N 2DY / GB
	[N/P]
Former [2006/37]	Wong, Kit Yee, et al D Young & Co 120 Holborn London EC1N 2DY / GB
Application number, filing date	05775059.8	20.07.2005
	[2006/37]
	WO2005US25808
Priority number, date	US20040589909P	20.07.2004 Original published format: US 589909 P
	US20040631849P	29.11.2004 Original published format: US 631849 P
	[2006/37]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2006012379
	Date:	02.02.2006
	Language:	EN
	[2006/05]
	Type:	A2 Application without search report
	No.:	EP1699773
	Date:	13.09.2006
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 02.02.2006 takes the place of the publication of the European patent application.
	[2006/37]
Search report(s)	International search report - published on:	EP	22.06.2006
Classification	IPC:	C07D307/88	[2006/37]
	CPC:	C07D307/83 (EP,US); A61K31/365 (EP,US); A61P35/00 (EP); A61P37/06 (EP); C07D307/88 (EP,US)
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2006/37]
Extension states	AL	Not yet paid
	BA	Not yet paid
	HR	Not yet paid
	MK	Not yet paid
	YU	Not yet paid
Title	German:	VERFAHREN ZUR HERSTELLUNG VON KRISTALLINEM MYCOPHENOLAT-NATRIUM	[2006/37]
	English:	PROCESSES FOR PREPARATION OF CRYSTALLINE MYCOPHENOLATE SODIUM	[2006/37]
	French:	PROCEDE POUR LA PREPARATION DE MYCOPHENOLATE SODIQUE CRISTALLINE	[2006/37]
Entry into regional phase	16.03.2006	National basic fee paid
	16.03.2006	Search fee paid
	16.03.2006	Designation fee(s) paid
	16.03.2006	Examination fee paid
Examination procedure	16.03.2006	Amendment by applicant (claims and/or description)
	16.03.2006	Examination requested [2006/37]
	11.05.2007	Despatch of a communication from the examining division (Time limit: M06)
	09.11.2007	Reply to a communication from the examining division
	06.08.2008	Cancellation of oral proceeding that was planned for 09.09.2008
	06.08.2008	Minutes of oral proceedings despatched
	22.08.2008	Despatch of communication that the application is refused, reason: substantive examination [2009/02]
	01.09.2008	Application refused, date of legal effect [2009/02]
	09.09.2008	Date of oral proceedings
	09.09.2008	Date of oral proceedings (cancelled)
Divisional application(s)	EP07023241.8 / EP1908756
Fees paid	Renewal fee
	28.07.2007	Renewal fee patent year 03
	15.07.2008	Renewal fee patent year 04
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited in	International search	[DA]ZA684959 ;
		[DA]WO9738689 (CIBA GEIGY AG [CH], et al) [DA] 1-8,13-24,29-36 * page 2, paragraph 3 *;
		[PDA]WO2004064806 (NOVARTIS AG [CH], et al) [PDA] 1-8,13-15,20-24,29-36 * page 15, line 15 - line 27; example 1 * * page 5, paragraph 2 *;
		[XD] - RIHS G ET AL, "SODIUM MYCOPHENOLATE", ACTA CRYSTALLOGRAPHICA SECTION C. CRYSTAL STRUCTURE COMMUNICATIONS, MUNKSGAARD, COPENHAGEN, DK, (200004), vol. C56, no. 7, ISSN 0108-2701, pages 432 - 433, XP008052367 [XD] 1-3,6,7,9-12,25 * page 433, column L, paragraph L * DOI: http://dx.doi.org/10.1107/S0108270100000524
		[DXA] - MAKARA G M ET AL, "Nuclear Magnetic Resonance and Molecular Modeling Study on Mycophenolic Acid: Implications for Bindung to Inosine Monophosphate Dehydrogenase", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1996), vol. 39, ISSN 0022-2623, pages 1236 - 1242, XP002360234 [DX] 20 * page 1241, column L, paragraph 3 * [A] 1-8,13-15,20-24,29-36 DOI: http://dx.doi.org/10.1021/jm950600m
		[DA] - DATABASE WPI, 0, Derwent World Patents Index, vol. 1970, no. 18, Database accession no. 1970-31237R, XP002360251 & ZA6804959 A 19700101 (LILLY & CO ELI) [DA] 1-8,13-24,29-36 * abstract *
		[A] - HILFIKER R ET AL, "Polymorphism-intergrated approach from high-throughput screening to crystallization optimization", JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, KLUWER, DORDRECHT,, NL, (2003), vol. 73, no. 2, ISSN 1388-6150, pages 429 - 440, XP002314915 [A] 1-38 * page 431, paragraph L - page 432, paragraph 5 * DOI: http://dx.doi.org/10.1023/A:1025409608944
		[A] - GUILLORY J K, "GENERATION OF POLYMORPHS, HYDRATES, SOLVATES, AND AMORPHOUS SOLIDS", POLYMORPHISM IN PHARMACEUTICAL SOLIDS, XX, XX, (1999), pages I - II,183, XP002350313 [A] 1-38 * page 188 - page 194; table 1 *
		[A] - GU C-H ET AL, "POLYMORPH SCREENING: INFLUENCE OF SOLVENTS ON THE RATE OF SOLVENT-MEDIATED POLYMORPHIC TRANSFORMATION", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN PHARMACEUTICAL ASSOCIATION. WASHINGTON, US, (200111), vol. 90, no. 11, ISSN 0022-3549, pages 1878 - 1890, XP001182144 [A] 1-37 * page 1879, column L * * page 1889, column L, paragraph L * DOI: http://dx.doi.org/10.1002/jps.1137
		[A] - DESROSIERS P ET AL, "High-throughput screening techniques for pre-formulation: SAlt selection and polymorh studies", ACTA CRYSTALLOGRAPHICA, MUNKSGAARD, COPENHAGEN, DK, (2002), vol. A58 (SUPPLEMENT), C9, ISSN 0365-110X, page 1, XP002978369 [A] 1-38 * column L, paragraph 1 *
		[PA] - GU C-H ET AL, "Grouping solvents by statistical analysis of solvent property parameters: implication to polymorph screening", INTERNATIONAL JOURNAL OF PHARMACEUTICS, AMSTERDAM, NL, (20040928), vol. 283, no. 1-2, ISSN 0378-5173, pages 117 - 125, XP004560638 [PA] 1-38 * abstract * DOI: http://dx.doi.org/10.1016/j.ijpharm.2004.06.021

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