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Extract from the Register of European Patents

EP About this file: EP1807513

EP1807513 - METHOD FOR THE PREPARATION OF CROSS-LINKED ENZYME AGGREGATES WITH IMPROVED PROPERTIES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.06.2017
Database last updated on 02.11.2024
Most recent event   Tooltip13.07.2018Lapse of the patent in a contracting statepublished on 15.08.2018  [2018/33]
Applicant(s)For all designated states
Clea Technologies BV
Julianalaan 136
2628 BL, Delft / NL
[2016/33]
Former [2007/29]For all designated states
Clea Technologies BV
Julianalaan 136
2628 BL, Delft / NL
Inventor(s)01 / SCHOEVAART, Willem, Robert, Klaas
Kwartelstraat 22
2623 PG Delft / NL
02 / VAN LANGEN, Lukas, Michael
Roodborstlaan 37
2623 HA Delft / NL
03 / VAN DEN DOOL, Ronald, Tako, Marinus
Dalkruid 1
4102 KR Culemborg / NL
04 / BOUMANS, Johannes, Wilhelmus, Leonardus
Jonge Linde 23
1191 RH Ouderkerk Aan De Amstel / NL
 [2016/33]
Former [2007/29]01 / SCHOEVAART, Willem, Robert, Klaas
Kwartelstraat 22
NL-2623 PG Delft / NL
02 / VAN LANGEN, Lukas, Michael
Roodborstlaan 37
NL-2623 HA Delft / NL
03 / VAN DEN DOOL, Ronald, Tako, Marinus
Dalkruid 1
NL-4102 KR Culemborg / NL
04 / BOUMANS, Johannes, Wilhelmus, Leonardus
Jonge Linde 23
NL-1191 RH Ouderkerk Aan De Amstel / NL
Representative(s)van der Kloet-Dorleijn, G.W.F.
Octrooibureau Griebling B.V.
Sportweg 10
5037 AC Tilburg / NL
[2016/33]
Former [2009/33]van der Kloet-Dorleijn, G.W.F.
Octrooibureau Griebling B.V. Sportweg 10
5037 AC Tilburg / NL
Former [2007/29]Kupecz, Arpad
Octrooibureau Los en Stigter B.V. Weteringschans 96
1017 XS Amsterdam / NL
Application number, filing date05797837.127.10.2005
[2007/29]
WO2005NL00767
Priority number, dateNL2004102736028.10.2004         Original published format: NL 1027360
[2007/29]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2006046865
Date:04.05.2006
Language:EN
[2006/18]
Type: A2 Application without search report 
No.:EP1807513
Date:18.07.2007
Language:EN
The application published by WIPO in one of the EPO official languages on 04.05.2006 takes the place of the publication of the European patent application.
[2007/29]
Type: B1 Patent specification 
No.:EP1807513
Date:17.08.2016
Language:EN
[2016/33]
Search report(s)International search report - published on:EP12.10.2006
ClassificationIPC:C12N9/96, C12N9/02, C12N9/20, C12P19/04
[2007/29]
CPC:
C12N9/96 (EP,US); C12N9/0061 (EP,US); C12N9/20 (EP,US);
C12Y110/03002 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/33]
Former [2007/29]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:VERFAHREN ZUR HERSTELLUNG QUERVERNETZTER ENZYMAGGREGATE MIT VERBESSERTEN EIGENSCHAFTEN[2015/14]
English:METHOD FOR THE PREPARATION OF CROSS-LINKED ENZYME AGGREGATES WITH IMPROVED PROPERTIES[2007/29]
French:PROCÉDÉ DE PRÉPARATION D'AGRÉGATS D'ENZYMES RÉTICULÉES PRÉSENTANT DES PROPRIÉTÉS AMÉLIORÉES[2007/29]
Former [2007/29]VERFAHREN ZURHERSTELLUNG QUERVERNETZTER ENZYMAGGREGATE MIT VERBESSERTEN EIGENSCHAFTEN
Entry into regional phase29.05.2007National basic fee paid 
29.05.2007Designation fee(s) paid 
29.05.2007Examination fee paid 
Examination procedure29.05.2007Examination requested  [2007/29]
07.04.2009Despatch of a communication from the examining division (Time limit: M06)
06.10.2009Reply to a communication from the examining division
31.03.2011Despatch of a communication from the examining division (Time limit: M06)
26.09.2011Request for decision received: Application is deemed to be withdrawn
06.10.2011Reply to a communication from the examining division
11.10.2011Result of request for decision (Application is deemed to be withdrawn): Request accepted
08.04.2014Despatch of a communication from the examining division (Time limit: M06)
08.10.2014Reply to a communication from the examining division
04.03.2015Communication of intention to grant the patent
21.08.2015Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
16.10.2015Fee for grant paid
16.10.2015Fee for publishing/printing paid
16.10.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  07.04.2009
Opposition(s)18.05.2017No opposition filed within time limit [2017/30]
Request for further processing for:The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent
16.10.2015Request for further processing filed
16.10.2015Full payment received (date of receipt of payment)
Request granted
30.10.2015Decision despatched
Fees paidRenewal fee
31.10.2007Renewal fee patent year 03
14.03.2008Renewal fee patent year 04
20.10.2009Renewal fee patent year 05
26.10.2010Renewal fee patent year 06
24.10.2011Renewal fee patent year 07
23.10.2012Renewal fee patent year 08
19.03.2014Renewal fee patent year 09
16.10.2014Renewal fee patent year 10
20.10.2015Renewal fee patent year 11
Penalty fee
Additional fee for renewal fee
31.10.201309   M06   Fee paid on   19.03.2014
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU27.10.2005
AT17.08.2016
BE17.08.2016
CY17.08.2016
CZ17.08.2016
EE17.08.2016
ES17.08.2016
FI17.08.2016
IS17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
MC17.08.2016
PL17.08.2016
RO17.08.2016
SE17.08.2016
SI17.08.2016
SK17.08.2016
TR17.08.2016
LU27.10.2016
CH31.10.2016
LI31.10.2016
FR02.11.2016
BG17.11.2016
GB17.11.2016
GR18.11.2016
PT19.12.2016
[2018/33]
Former [2018/32]HU27.10.2005
AT17.08.2016
BE17.08.2016
CY17.08.2016
CZ17.08.2016
EE17.08.2016
ES17.08.2016
FI17.08.2016
IS17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
MC17.08.2016
PL17.08.2016
RO17.08.2016
SE17.08.2016
SI17.08.2016
SK17.08.2016
TR17.08.2016
LU27.10.2016
CH31.10.2016
LI31.10.2016
FR02.11.2016
BG17.11.2016
GB17.11.2016
GR18.11.2016
PT19.12.2016
Former [2018/29]HU27.10.2005
AT17.08.2016
BE17.08.2016
CY17.08.2016
CZ17.08.2016
EE17.08.2016
ES17.08.2016
FI17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
MC17.08.2016
PL17.08.2016
RO17.08.2016
SE17.08.2016
SI17.08.2016
SK17.08.2016
TR17.08.2016
LU27.10.2016
CH31.10.2016
LI31.10.2016
FR02.11.2016
BG17.11.2016
GB17.11.2016
GR18.11.2016
PT19.12.2016
Former [2018/28]HU27.10.2005
AT17.08.2016
BE17.08.2016
CY17.08.2016
CZ17.08.2016
EE17.08.2016
ES17.08.2016
FI17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
MC17.08.2016
PL17.08.2016
RO17.08.2016
SE17.08.2016
SI17.08.2016
SK17.08.2016
LU27.10.2016
CH31.10.2016
LI31.10.2016
FR02.11.2016
BG17.11.2016
GB17.11.2016
GR18.11.2016
PT19.12.2016
Former [2018/01]AT17.08.2016
BE17.08.2016
CZ17.08.2016
EE17.08.2016
ES17.08.2016
FI17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
PL17.08.2016
RO17.08.2016
SE17.08.2016
SI17.08.2016
SK17.08.2016
LU27.10.2016
CH31.10.2016
LI31.10.2016
FR02.11.2016
BG17.11.2016
GB17.11.2016
GR18.11.2016
PT19.12.2016
Former [2017/42]AT17.08.2016
BE17.08.2016
CZ17.08.2016
EE17.08.2016
ES17.08.2016
FI17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
PL17.08.2016
RO17.08.2016
SE17.08.2016
SI17.08.2016
SK17.08.2016
LU27.10.2016
CH31.10.2016
LI31.10.2016
FR02.11.2016
BG17.11.2016
GR18.11.2016
PT19.12.2016
Former [2017/37]AT17.08.2016
BE17.08.2016
CZ17.08.2016
EE17.08.2016
ES17.08.2016
FI17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
PL17.08.2016
RO17.08.2016
SE17.08.2016
SI17.08.2016
SK17.08.2016
CH31.10.2016
LI31.10.2016
FR02.11.2016
BG17.11.2016
GR18.11.2016
PT19.12.2016
Former [2017/35]AT17.08.2016
BE17.08.2016
CZ17.08.2016
EE17.08.2016
ES17.08.2016
FI17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
PL17.08.2016
RO17.08.2016
SE17.08.2016
SK17.08.2016
CH31.10.2016
LI31.10.2016
FR02.11.2016
BG17.11.2016
GR18.11.2016
PT19.12.2016
Former [2017/34]AT17.08.2016
BE17.08.2016
CZ17.08.2016
EE17.08.2016
ES17.08.2016
FI17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
PL17.08.2016
RO17.08.2016
SE17.08.2016
SK17.08.2016
FR02.11.2016
BG17.11.2016
GR18.11.2016
PT19.12.2016
Former [2017/23]AT17.08.2016
BE17.08.2016
CZ17.08.2016
EE17.08.2016
ES17.08.2016
FI17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
PL17.08.2016
RO17.08.2016
SE17.08.2016
SK17.08.2016
BG17.11.2016
GR18.11.2016
PT19.12.2016
Former [2017/13]AT17.08.2016
ES17.08.2016
FI17.08.2016
IT17.08.2016
LT17.08.2016
LV17.08.2016
PL17.08.2016
SE17.08.2016
BE31.10.2016
GR18.11.2016
PT19.12.2016
Former [2017/12]AT17.08.2016
ES17.08.2016
FI17.08.2016
IT17.08.2016
LT17.08.2016
PL17.08.2016
SE17.08.2016
BE31.10.2016
GR18.11.2016
PT19.12.2016
Former [2017/10]FI17.08.2016
IT17.08.2016
LT17.08.2016
PL17.08.2016
SE17.08.2016
BE31.10.2016
Former [2017/09]FI17.08.2016
IT17.08.2016
LT17.08.2016
Former [2017/07]LT17.08.2016
Cited inInternational search[XY]EP1088887  (DSM NV [NL]) [X] 1,2,9,11,14,22 * the whole document * * especially Example I * [Y] 1-24;
 [Y]WO9912959  (ALTUS BIOLOGICS INC [US], et al) [Y] 1-24 * page 51 - page 53; example 3 *;
 [Y]US5437993  (VISURI KALEVI [FI]) [Y] 1,2,7-24 * the whole document *;
 [Y]EP1418231  (AVANTIUM INT BV [NL]) [Y] 15,16 * page 2, line 37 - line 38 *;
 [Y]  - VUOLANTO A, Cross-linked protein crystal technology in bioseparation and biocatalytic applications, ESPOO, FINLAND, HELSINKI UNIVERSITY OF TECHNOLOGY, (20040820), XP002330803 [Y] 1-24 * page 10 - page 13, paragraph 1 *
 [Y]  - LOPEZ-SERRANO P ET AL, "CROSS-LINKED ENZYME AGGREGATES WITH ENHANCED ACTIVITY: APPLICATION TO LIPASES", BIOTECHNOLOGY LETTERS, KEW, SURREY, GB, (200208), vol. 24, no. 16, ISSN 0141-5492, pages 1379 - 1383, XP009003775 [Y] 1-24 * the whole document * * especially page 1379, left column, first paragraph *

DOI:   http://dx.doi.org/10.1023/A:1019863314646
 [XY]  - SCHOEVAART R ET AL, "Preparation, optimization, and structures of cross-linked enzyme aggregates (CLEAs)", BIOTECHNOLOGY AND BIOENGINEERING, (20040920), vol. 87, no. 6, ISSN 0006-3592, pages 754 - 762, XP002394547 [X] 1,2,9,11,14,22 * the whole document * * especially tabel I.11 * [Y] 1-24

DOI:   http://dx.doi.org/10.1002/bit.20184
 [A]  - POZNANSKY M, "Soluble enzyme-albumin conjugates: New possibilities for enzyme replacement therapy", METHODS IN ENZYMOLOGY, (1988), vol. 137, no. d, pages 566 - 574, XP002330802 [A] * page 568, paragraph 2 - page 570 *

DOI:   http://dx.doi.org/10.1016/0076-6879(88)37052-7
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