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Extract from the Register of European Patents

EP About this file: EP1799825

EP1799825 - APTAMER REGULATED NUCLEIC ACIDS AND USES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  04.05.2012
Database last updated on 20.09.2024
Most recent event   Tooltip04.10.2013Lapse of the patent in a contracting state
New state(s): HU		published on 06.11.2013  [2013/45]
Applicant(s)For all designated states
The California Institute of Technology
1200 East California Boulevard Pasadena
California 91125 / US
[2007/26]
Inventor(s)01 / SMOLKE, Christina, D.
856 South Marengo, Nr. 2
Pasadena, CA 91106 / US
02 / BAYER, Travis, S.
791 East California Boulevard
Pasadena, CA 91106 / US
 [2007/43]
Former [2007/26]01 / SMOLKE, Christina, D.
315 Sycamore Glen
Pasadena, CA 91105 / US
02 / BAYER, Travis, S.
791 East California Boulevard
Pasadena, CA 91106 / US
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2008/35]Vossius & Partner
Siebertstrasse 3
81675 München / DE
Former [2007/26]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date05803129.505.10.2005
[2007/26]
WO2005US36161
Priority number, dateUS20040615977P05.10.2004         Original published format: US 615977 P
US20050641658P06.01.2005         Original published format: US 641658 P
[2007/26]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2006042112
Date:20.04.2006
Language:EN
[2006/16]
Type: A2 Application without search report 
No.:EP1799825
Date:27.06.2007
Language:EN
The application published by WIPO in one of the EPO official languages on 20.04.2006 takes the place of the publication of the European patent application.
[2007/26]
Type: B1 Patent specification 
No.:EP1799825
Date:29.06.2011
Language:EN
[2011/26]
Search report(s)International search report - published on:EP21.12.2006
ClassificationIPC:C12N15/113, C12N15/115, C12N15/67, C12Q1/68, A61K31/713
[2010/43]
CPC:
C12N15/111 (EP,US); C12Q1/686 (US); A61P3/04 (EP);
A61P3/10 (EP); A61P31/00 (EP); A61P31/04 (EP);
A61P35/00 (EP); A61P37/04 (EP); A61P43/00 (EP);
C12N15/113 (EP,US); C12N15/115 (EP,US); C12N15/635 (EP,US);
C12Q1/6897 (EP,US); A61K38/00 (EP,US); C12N2310/11 (EP,US);
C12N2310/111 (EP,US); C12N2310/14 (EP,US); C12N2310/16 (EP,US) (-)
C-Set:
C12Q1/6897, C12Q2525/205 (EP,US)
Former IPC [2007/26]C12N15/11, C12N15/67, C12Q1/68, A61K38/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2007/26]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
YUNot yet paid
TitleGerman:APTAMER-REGULIERTE NUKLEINSÄUREN UND VERWENDUNGEN DAVON[2007/26]
English:APTAMER REGULATED NUCLEIC ACIDS AND USES THEREOF[2007/26]
French:ACIDES NUCLEIQUES A REGULATION D'APTAMERES ET LEURS UTILISATIONS[2007/26]
Entry into regional phase04.04.2007National basic fee paid 
04.04.2007Designation fee(s) paid 
04.04.2007Examination fee paid 
Examination procedure04.04.2007Examination requested  [2007/26]
11.02.2008Despatch of a communication from the examining division (Time limit: M04)
17.06.2008Reply to a communication from the examining division
13.03.2009Despatch of a communication from the examining division (Time limit: M04)
23.07.2009Reply to a communication from the examining division
30.12.2010Communication of intention to grant the patent
04.05.2011Fee for grant paid
04.05.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.02.2008
Opposition(s)30.03.2012No opposition filed within time limit [2012/23]
Fees paidRenewal fee
29.10.2007Renewal fee patent year 03
14.10.2008Renewal fee patent year 04
13.10.2009Renewal fee patent year 05
12.10.2010Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT29.06.2011
BE29.06.2011
CY29.06.2011
CZ29.06.2011
DK29.06.2011
EE29.06.2011
FI29.06.2011
HU29.06.2011
IT29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
TR29.06.2011
BG29.09.2011
GR30.09.2011
IE05.10.2011
LU05.10.2011
ES10.10.2011
IS29.10.2011
MC31.10.2011
PT31.10.2011
[2013/45]
Former [2013/44]AT29.06.2011
BE29.06.2011
CY29.06.2011
CZ29.06.2011
DK29.06.2011
EE29.06.2011
FI29.06.2011
IT29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
TR29.06.2011
BG29.09.2011
GR30.09.2011
IE05.10.2011
LU05.10.2011
ES10.10.2011
IS29.10.2011
MC31.10.2011
PT31.10.2011
Former [2013/29]AT29.06.2011
BE29.06.2011
CY29.06.2011
CZ29.06.2011
DK29.06.2011
EE29.06.2011
FI29.06.2011
IT29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
BG29.09.2011
GR30.09.2011
IE05.10.2011
LU05.10.2011
ES10.10.2011
IS29.10.2011
MC31.10.2011
PT31.10.2011
Former [2013/25]AT29.06.2011
BE29.06.2011
CY29.06.2011
CZ29.06.2011
DK29.06.2011
EE29.06.2011
FI29.06.2011
IT29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
GR30.09.2011
IE05.10.2011
LU05.10.2011
ES10.10.2011
IS29.10.2011
MC31.10.2011
PT31.10.2011
Former [2013/22]AT29.06.2011
BE29.06.2011
CY29.06.2011
CZ29.06.2011
DK29.06.2011
EE29.06.2011
FI29.06.2011
IT29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
GR30.09.2011
IE05.10.2011
ES10.10.2011
IS29.10.2011
MC31.10.2011
PT31.10.2011
Former [2012/47]AT29.06.2011
BE29.06.2011
CY29.06.2011
CZ29.06.2011
DK29.06.2011
EE29.06.2011
FI29.06.2011
IT29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
GR30.09.2011
IE05.10.2011
IS29.10.2011
MC31.10.2011
PT31.10.2011
Former [2012/31]AT29.06.2011
BE29.06.2011
CY29.06.2011
CZ29.06.2011
DK29.06.2011
EE29.06.2011
FI29.06.2011
IT29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
GR30.09.2011
IS29.10.2011
MC31.10.2011
PT31.10.2011
Former [2012/25]AT29.06.2011
BE29.06.2011
CY29.06.2011
CZ29.06.2011
EE29.06.2011
FI29.06.2011
IT29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
GR30.09.2011
IS29.10.2011
MC31.10.2011
PT31.10.2011
Former [2012/23]AT29.06.2011
BE29.06.2011
CY29.06.2011
CZ29.06.2011
EE29.06.2011
FI29.06.2011
IT29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
GR30.09.2011
IS29.10.2011
PT31.10.2011
Former [2012/12]AT29.06.2011
BE29.06.2011
CY29.06.2011
CZ29.06.2011
EE29.06.2011
FI29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
GR30.09.2011
IS29.10.2011
PT31.10.2011
Former [2012/11]AT29.06.2011
BE29.06.2011
CZ29.06.2011
EE29.06.2011
FI29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
PL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
GR30.09.2011
IS29.10.2011
PT31.10.2011
Former [2012/10]AT29.06.2011
BE29.06.2011
CZ29.06.2011
EE29.06.2011
FI29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
RO29.06.2011
SE29.06.2011
SI29.06.2011
SK29.06.2011
GR30.09.2011
IS29.10.2011
PT31.10.2011
Former [2012/09]AT29.06.2011
BE29.06.2011
CZ29.06.2011
EE29.06.2011
FI29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
SE29.06.2011
SI29.06.2011
GR30.09.2011
IS29.10.2011
PT31.10.2011
Former [2012/08]AT29.06.2011
BE29.06.2011
EE29.06.2011
FI29.06.2011
LT29.06.2011
LV29.06.2011
NL29.06.2011
SE29.06.2011
SI29.06.2011
GR30.09.2011
IS29.10.2011
Former [2012/05]AT29.06.2011
BE29.06.2011
FI29.06.2011
LT29.06.2011
LV29.06.2011
SE29.06.2011
SI29.06.2011
GR30.09.2011
Former [2011/52]AT29.06.2011
FI29.06.2011
LT29.06.2011
LV29.06.2011
SE29.06.2011
SI29.06.2011
GR30.09.2011
Former [2011/50]FI29.06.2011
LT29.06.2011
LV29.06.2011
SE29.06.2011
SI29.06.2011
GR30.09.2011
Former [2011/49]FI29.06.2011
LT29.06.2011
SE29.06.2011
GR30.09.2011
Former [2011/48]LT29.06.2011
SE29.06.2011
Cited inInternational search[A]WO9904800  (GENITRIX LLC [US], et al) [A] * the whole document *;
 [A]US2002150996  (NILSEN-HAMILTON MARIT [US]) [A] * the whole document *;
 [X]  - WINKLER W.C. ET AL., "An mRNA structure that controls gene expression by binding FMN", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, (20021210), vol. 99, no. 25, pages 15908 - 15913, XP002374934 [X] 1,5,9,17,18,29,31,32,34-36 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.212628899
 [X]  - WINKLER W.C. AND BREAKER R.R., "Genetic control by metabolite-binding riboswitches", CHEMBIOCHEM, (2003), vol. 4, pages 1024 - 1032, XP002374935 [X] 1,5,9,17,18,29,31,32,34-36 * the whole document *

DOI:   http://dx.doi.org/10.1002/cbic.200300685
 [X]  - FREDRIKSSON S. ET AL., "Protein detection using proximity-dependent DNA ligation assays", NATURE BIOTECHNOLOGY, (200205), vol. 20, pages 473 - 477, XP002375040 [X] 1,8,14,17,18,31,33,34,37 * the whole document *

DOI:   http://dx.doi.org/10.1038/nbt0502-473
 [X]  - FAMULOK M., "Bringing picomolar protein detection into proximity", NATURE BIOTECHNOLOGY, (200205), vol. 20, pages 448 - 449, XP002375041 [X] 1,8,14,17,18,31,33,34,37 * the whole document *

DOI:   http://dx.doi.org/10.1038/nbt0502-448
 [AD]  - NUTIU R. AND LI Y., "Structure-switching signaling aptamers: transducing molecular recognition into fluorescence signaling", CHEMISTRY, (20040419), vol. 10, no. 8, pages 1868 - 1876, XP002374936 [AD] * figure 5 * * the whole document *

DOI:   http://dx.doi.org/10.1002/chem.200305470
 [A]  - NUTIU R. AND LI Y., "Structure-switching signaling aptamers", THE JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (2003), vol. 125, no. 16, page 4771-4778/S1, XP002374937 [A] * the whole document *

DOI:   http://dx.doi.org/10.1021/ja028962o
 [AD]  - BUSKIRK A.R. ET AL., "Engineering a ligand-dependent RNA transcriptional activator", CHEMISTRY & BIOLOGY, (20040820), vol. 11, no. 8, pages 1157 - 1163, XP002374938 [AD] * figure 1 * * the whole document *

DOI:   http://dx.doi.org/10.1016/j.chembiol.2004.05.017
 [A]  - BUSKIRK A.R. ET AL., "In vivo evolution of an RNA-based transcriptional activator", CHEMISTRY & BIOLOGY, (200306), vol. 10, pages 533 - 540, XP002374939 [A] * the whole document *

DOI:   http://dx.doi.org/10.1016/S1074-5521(03)00109-1
 [AD]  - HESSELBERTH J.R. ET AL., "Simultaneous detection of diverse analytes with an aptazyme ligase array", ANALYTICAL BIOCHEMISTRY, (20030115), vol. 312, no. 2, pages 106 - 112, XP002374940 [AD] * figure 2 * * the whole document *

DOI:   http://dx.doi.org/10.1016/S0003-2697(02)00441-4
 [A]  - LUZI E. ET AL., "New trends in affinity sensing: aptamers for ligand binding", TRENDS IN ANALYTICAL CHEMISTRY, (200312), vol. 22, no. 11, pages 810 - 818, XP002374941 [A] * the whole document *

DOI:   http://dx.doi.org/10.1016/S0165-9936(03)01208-1
 [A]  - SILVERMAN SCOTT K., "Rube Goldberg goes (ribo)nuclear ? Molecular switches and sensors made from RNA", RNA, New York, (200304), vol. 9, no. 4, pages 377 - 383, XP002374942 [A] * the whole document *

DOI:   http://dx.doi.org/10.1261/rna.2200903
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