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Extract from the Register of European Patents

EP About this file: EP1804782

EP1804782 - USE OF (Z)-2-CYANO-3-HYDROXY-BUT-2-ENOIC ACID-(4'-TRIFLUOROMETHYLPHENYL)-AMIDE FOR TREATING INFLAMMATORY BOWEL DISEASE [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  23.04.2010
Database last updated on 13.11.2024
Most recent event   Tooltip23.04.2010Refusal of applicationpublished on 26.05.2010  [2010/21]
Applicant(s)For all designated states
Aventis Pharmaceuticals Inc.
300 Somerset Corporate Boulevard
Bridgewater, New Jersey 08807-2854 / US
[N/P]
Former [2007/28]For all designated states
Aventis Pharmaceuticals Inc
300 Somerset Corporate Boulevard
Bridgewater, New Jersey 08807-2854 / US
Inventor(s)01 / SCHEYER, Richard, D.
3415 Round Hill Road
Branchburg, NJ 08876 / US
02 / STYREN, Scot, D.
117 Sleepy Hollow Drive
Niantic, CT 06357 / US
 [2007/28]
Representative(s)Morel-Pécheux, Muriel
Sanofi
Département Brevets
54, rue La Boétie
75008 Paris / FR
[N/P]
Former [2007/28]Morel-Pécheux, Muriel
Aventis Pharma SA, 20, avenue Raymond Aron
92160 Antony Cedex / FR
Application number, filing date05812243.318.10.2005
[2007/28]
WO2005US37161
Priority number, dateUS20040620255P19.10.2004         Original published format: US 620255 P
[2007/28]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2006044741
Date:27.04.2006
Language:EN
[2006/17]
Type: A1 Application with search report 
No.:EP1804782
Date:11.07.2007
Language:EN
The application published by WIPO in one of the EPO official languages on 27.04.2006 takes the place of the publication of the European patent application.
[2007/28]
Search report(s)International search report - published on:EP27.04.2006
ClassificationIPC:A61K31/165, A61P1/00, A61P29/00
[2007/28]
CPC:
A61K31/165 (EP,US); A61K31/167 (KR); A61K31/277 (EP,US);
A61P1/00 (EP); A61P1/04 (EP); A61P29/00 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2007/28]
Extension statesAL21.05.2007
BA21.05.2007
HR21.05.2007
MK21.05.2007
YU21.05.2007
TitleGerman:VERWENDUNG VON (Z)-2-CYANO-3-HYDROXY-BUT-2-ENSÄURE-(4'-TRIFLUOROMETHYLPHENYL)-AMID ZUR BEHANDLUNG ENTZÜNDLICHER DARMERKRANKUNGEN[2007/28]
English:USE OF (Z)-2-CYANO-3-HYDROXY-BUT-2-ENOIC ACID-(4'-TRIFLUOROMETHYLPHENYL)-AMIDE FOR TREATING INFLAMMATORY BOWEL DISEASE[2007/28]
French:EMPLOI DU (4'-TRIFLUOROMETHYLPHENYL)AMIDE DE L'ACIDE (Z)-2-CYANO-3-HYDROXY-BUT-2-ENOIQUE DANS LE TRAITEMENT D AFFECTIONS ABDOMINALES INFLAMMATOIRES[2007/28]
Entry into regional phase21.05.2007National basic fee paid 
21.05.2007Designation fee(s) paid 
21.05.2007Examination fee paid 
Examination procedure21.05.2007Examination requested  [2007/28]
03.07.2007Amendment by applicant (claims and/or description)
30.08.2007Despatch of a communication from the examining division (Time limit: M06)
04.03.2008Reply to a communication from the examining division
29.07.2008Despatch of a communication from the examining division (Time limit: M04)
04.12.2008Reply to a communication from the examining division
03.12.2009Application refused, date of legal effect [2010/21]
03.12.2009Date of oral proceedings
07.01.2010Despatch of communication that the application is refused, reason: substantive examination [2010/21]
07.01.2010Minutes of oral proceedings despatched
Fees paidRenewal fee
24.10.2007Renewal fee patent year 03
31.03.2008Renewal fee patent year 04
13.10.2009Renewal fee patent year 05
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Cited inInternational search[X]US5780592  (MUELLNER STEFAN [DE], et al) [X] 1,3-5 * column 5, line 41 * * example 1 * * claim 3 *;
 [X]WO9954286  (WAYNE HUGHES INST [US]) [X] 1,2 * claims 1,18 * * table 1 *;
 [A]WO02080897  (AVENTIS PHARMA INC [US], et al) [A] 1-5 * the whole document *;
 [A]WO2004024676  (SCHEBO & REG [DE], et al) [A] 1-5 * figure 2b * * page 9, paragraph 1 * * page 16, paragraph L * * claim 11 *;
 [PA]  - STEINHILBER D, "Pharmacology of immunosuppressive agents", PHARMAZIE IN UNSERER ZEIT 2005 GERMANY, (2005), vol. 34, no. 4, ISSN 0048-3664, pages 276 - 281, XP002365151 [PA] 1-5 * page 280, column R * * figure 9 *

DOI:   http://dx.doi.org/10.1002/pauz.200500127
 [AD]  - KIMURA K ET AL, "Concurrence of inflammatory bowel disease and multiple sclerosis", MAYO CLINIC PROCEEDINGS 2000 UNITED STATES, (2000), vol. 75, no. 8, ISSN 0025-6196, pages 802 - 806, XP009060726 [AD] 1-5 * the whole document *

DOI:   http://dx.doi.org/10.4065/75.8.802
Examination   - PRAPAJATI D.N. ET AL, "leflunomide treatment of Chron's disease patients intolenrant to standard immunomodulator therapy", JOURNAL OF CLINICAL GASTROENTEROLOGY, (2003), vol. 37, no. 2, pages 125 - 128, XP009060723
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