-
EP1891019
European procedure
Extract from the Register of European Patents
EP About this file: EP1891019
| EP1891019 - 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS [Right-click to bookmark this link] | |||
| Former [2008/09] | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | ||
| [2012/02] | Status | No opposition filed within time limit Status updated on 31.05.2013 Database last updated on 06.07.2024 | Most recent event Tooltip | 31.05.2013 | No opposition filed within time limit | published on 03.07.2013 [2013/27] | Applicant(s) | For all designated states Aventis Pharmaceuticals Inc. 55 Corporate Drive Bridgewater, NJ 08807 / US | [2013/06] |
| Former [2008/09] | For all designated states Aventis Pharmaceuticals Inc. 300 Somerset Corporate Boulevard Bridgewater, NJ 08807 / US | Inventor(s) | 01 /
LIM, Sungtaek 27 Aberdeen Circle Flemington, NJ 08822 / US | 02 /
HARRIS, Keith John 3 Tiger Brook Lane Chester, NJ 07930 / US | 03 /
STEFANY, David 287 Gemini Drive Hillsborough, NJ 08844 / US | 04 /
GARDNER, Charles J. 644 S. Fifth Avenue Royersford, PA 19646 / US | 05 /
CAO, Bin 296 Thistle Lane Bedminster, NJ 07921 / US | 06 /
BOFFEY, Ray Argenta Discovery Ltd. 8/9 Spire Green Centre Flex Meadow, Harlow Essex CM19 5TR, UK / GB | 07 /
GILLESPY, Timothy A. 42 Foxhill Lane Hillsborough, NJ 08844 / US | 08 /
AGUIAR, Joacy, C. 41 Wilson Avenue, Apartment 4D Newark, NJ 07105 / US | 09 /
HUNT, Hazel J. 7/9 Spire Green Centre Harlow, Essex CM19 5TR, UK / GB | 10 /
DECHAUX, Elsa A. 7/9 Spire Green Centre Harlow, Essex CM19 5TR, UK / GB | [2012/30] |
| Former [2008/09] | 01 /
LIM, Sungtaek 27 Aberdeen Circle Flemington, NJ 08822 / US | ||
| 02 /
HARRIS, Keith John 3 Tiger Brook Lane Chester, NJ 07930 / US | |||
| 03 /
STEFANY, David 287 Gemini Drive Hillsborough, NJ 08844 / US | |||
| 04 /
GARDNER, Charles J. 644 S. Fifth Avenue Royersford, PA 19646 / US | |||
| 05 /
CAO, Bin 296 Thistle Lane Bedminster, NJ 07921 / US | |||
| 06 /
BOFFEY, Ray Argenta Discovery Ltd. 8/9 Spire Green Centre Flex Meadow, Harlow Essex CM19 5TR, UK / GB | |||
| 07 /
GILLESPY, Timothy A. 42 Foxhill Lane Hillsborough, NJ 08844 / US | |||
| 08 /
AGUIAR, Joacy, C. 41 Wilson Avenue, Apartment 4D Newark, NJ 07105 / US | |||
| 09 /
HUNT, Hazel J. 7/9 Spire Green Centre Harlow, Essex CM19 5TR, UK / GB | |||
| 10 /
DECHAUX, Elsa A. 7/9 Spire Green Centre Harlow, Essex CM19 5TR, UK / GB | Representative(s) | Ori, Janos, et al Chinoin Gyogyszer és Vegyészeti Termékek Gyara Zrt. To u. 1-5. H-1045 Budapest / HU | [2012/30] |
| Former [2008/09] | Ori, Janos, et al Chinoin Gyogyszer és Vegyészeti Termékek Gyara Rt. To u. 1-5. H-1045 Budapest / HU | Application number, filing date | 05812481.9 | 14.10.2005 | [2008/09] | WO2005US37148 | Priority number, date | US20040619272P | 15.10.2004 Original published format: US 619272 P | [2008/09] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2006044732 | Date: | 27.04.2006 | Language: | EN | [2006/17] | Type: | A2 Application without search report | No.: | EP1891019 | Date: | 27.02.2008 | Language: | EN | The application published by WIPO in one of the EPO official languages on 27.04.2006 takes the place of the publication of the European patent application. | [2008/09] | Type: | B1 Patent specification | No.: | EP1891019 | Date: | 25.07.2012 | Language: | EN | [2012/30] | Search report(s) | International search report - published on: | EP | 23.11.2006 | Classification | IPC: | C07D239/46, C07D409/04, C07D413/04, C07D403/04 | [2008/09] | CPC: |
C07D239/42 (EP,US);
C07D239/46 (NO);
C07D239/47 (EP,KR,US);
A61K31/50 (NO);
A61K31/505 (NO);
A61P11/00 (EP);
A61P11/02 (EP);
A61P17/00 (EP);
A61P17/04 (EP);
A61P27/02 (EP);
A61P37/00 (EP);
A61P37/08 (EP);
A61P43/00 (EP);
C07D239/48 (EP,US);
C07D401/04 (EP,KR,US);
C07D401/12 (EP,KR,US);
C07D401/14 (EP,US);
C07D403/04 (EP,KR,NO,US);
C07D403/10 (EP,US);
C07D403/12 (EP,US);
C07D405/04 (EP,US);
C07D405/10 (EP,US);
C07D405/12 (EP,US);
C07D405/14 (EP,US);
C07D409/04 (EP,NO,US);
C07D409/12 (EP,US);
C07D413/04 (EP,NO,US);
C07D413/10 (EP,US);
C07D413/12 (EP,US);
C07D413/14 (EP,US);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2008/09] | Extension states | AL | 23.05.2007 | BA | 23.05.2007 | HR | 23.05.2007 | MK | 23.05.2007 | YU | 23.05.2007 | Title | German: | 2,6-SUBSTITUIERTES-4-MONOSUBSTITUIRTE AMINOPYRIMIDINE ALS PROSTAGLANDIN-D2-REZEPTOR-ANTAGONISTEN | [2012/02] | English: | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | [2012/02] | French: | AMINOPYRIMIDINES 2,6-SUBSTITUÉ ET 4-MONOSUBSTITUÉ COMME ANTAGONISTES DU RÉCEPTEUR DE PROSTAGLANDINE-D2 | [2012/02] |
| Former [2008/09] | 2,6-SUBSTITUIERTES-4-MONOSUBSTITUIRTES AMINOPYRIMIDIN ALS PROSTAGLANDIN-D2-REZEPTOR-ANTAGONISTEN | ||
| Former [2008/09] | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | ||
| Former [2008/09] | AMINOPYRIMIDINE 2,6-SUBSTITUÉ ET 4-MONOSUBSTITUÉ COMME ANTAGONISTES DU RÉCEPTEUR DE PROSTAGLANDINE-D2 | Entry into regional phase | 15.05.2007 | National basic fee paid | 23.05.2007 | Designation fee(s) paid | 23.05.2007 | Examination fee paid | Examination procedure | 14.08.2006 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 23.05.2007 | Examination requested [2008/09] | 02.02.2010 | Despatch of a communication from the examining division (Time limit: M06) | 30.07.2010 | Reply to a communication from the examining division | 02.02.2012 | Communication of intention to grant the patent | 06.06.2012 | Fee for grant paid | 06.06.2012 | Fee for publishing/printing paid | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 02.02.2010 | Opposition(s) | 26.04.2013 | No opposition filed within time limit [2013/27] | Fees paid | Renewal fee | 31.10.2007 | Renewal fee patent year 03 | 14.10.2008 | Renewal fee patent year 04 | 13.10.2009 | Renewal fee patent year 05 | 12.10.2010 | Renewal fee patent year 06 | 11.10.2011 | Renewal fee patent year 07 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | MC | 31.10.2012 | IS | 25.11.2012 | [2013/24] |
| Former [2013/10] | IS | 25.11.2012 | Cited in | International search | [X]GB1143167 (UCB SA) [X] 1,5-7,16,17,19,39 * Claims 1, 60, 71. *; | [X]DE4031798 (HOECHST AG [DE]) [X] 1,3,5-7,16,17,19 * Abstract; claims 1-6; page 12, example 4. *; | [X]WO9950251 (CANCER RES CAMPAIGN TECH [GB], et al) [X] 1,2,5-7,16,17,39 * Claims 1, 28; page 29: 2-amino-6-benzyl- amino-4-cyclohexylmethyloxypyrimidine. *; | US6169086 [ ] (EJIMA AKIO [JP], et al) [ ] * Column 76, example 58.1. *; | [A]WO0208186 (MERCK FROSST CANADA INC [CA], et al) [A] 1-47* Abstract; claims. *; | [X]US6380263 (PRUCHE FRANCIS [FR], et al) [X] 1-7,12-14,16,17,19 * Abstract; claim 1; claim 4, column 10, line 38. *; | [X]WO03031406 (IRM LLC [US], et al) [X] 1-7,11-14,16,17,19,39 * Claims 57, 72; page 42, compound 5; page 44, compound 5. *; | [A]WO03062200 (MERCK FROSST CANADA INC [CA], et al) [A] 1-47 * Abstract; claims. *; | [X]US2003187007 (CAO SHELDON XIAODONG [US], et al) [X] 1-7,9,16,18,19,39 * Abstract; claims 1-13; paragraphs [0427]-[0429], [1232]-[1238]; examples 86-87, 93, 96-97, 100, 102, 106, 108, 112, 115-118. *; | [X]WO2004043926 (BAYER HEALTHCARE AG [DE], et al) [X] 1-7,11-14,16,17,19,39 * Abstract; claims 1-22; page 81, example 1-38; page 83, example 1-54. *; | [PX]WO2005011758 (CIBA SC HOLDING AG [CH], et al) [PX] 1-7,9,11-14,16,17,19 * Claims 1, 20; page 10, example PY59. *; | [X] - BEILSTEIN, Beilstein Institut zur Förderung der Wissenschaften, Frankfurt/Main, DE, Database accession no. 9073007, 9075686 (BRN)., XP002374970 [X] 1-7,11-14,16,17,19 * abstract * | [ ] - DING, S. ET AL., "A Combinatorial Scaffold Approach toward Kinase-Directed Heterocycle Libraries", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, (2002), vol. 124, no. 8, ISSN 0002-7863, pages 1594 - 1596, XP002210160 [ ] * Page 1596, table 2. * DOI: http://dx.doi.org/10.1021/ja0170302 | [X] - VISHWAKARMA, J. N. ET AL., "Reactions of polarized ketene S,N-acetals with guanidine: a facile route to novel 5,6-substituted 2-amino-4-N-alkyl/aryl/N- azacycloalkylaminopyrimidines", INDIAN JOURNAL OF CHEMISTRY, SECTION B: ORGANIC, INCL. MEDICINAL, PUBLICATIONS & INFORMATIONS DIRECTORATE, NEW DELHI, IN, (198505), vol. 24B, no. 5, ISSN 0019-5103, pages 466 - 471, XP009020490 [X] 1-7,11-14,16,17,19 * Page 467, compounds 2d, 2e. * | [X] - TRANTOLO, D. J. ET AL., "Inhibitors of Bacillus subtilis DNA polymerase III.", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1986), vol. 29, ISSN 0022-2623, pages 676 - 681, XP002119935 [X] 1-7,11-14,16,17,39 * Page 677, table II, compounds 18-25, 27, and 28. * DOI: http://dx.doi.org/10.1021/jm00155a016 | [X] - MDL PATENT CHEMISTRY, Elsevier MDL, San Leandro, CA, USA, Database accession no. 1000626 (Patent Compound Registry Number)., XP002374971 [X] 1-7,12,13,16,17,19 * abstract * | [X] - WADE, J. V.; KRUEGER, C. A., "Suzuki Cross-Coupling of Solid-Supported Chloropyrimidines with Arylboronic Acids", J. COMB. CHEM., (2003), vol. 5, no. 3, pages 267 - 272, XP009064593 [X] 1-7,11-14,16,17,19 * Page 268, table 2, compound 10b. * DOI: http://dx.doi.org/10.1021/cc020061o | [X] - MA, Y. ET AL., "Combibatorial synthesis of Substituted Biaryl and heterocyclic Arylamines", J. COMB. CHEM., (200405), vol. 6, no. 3, pages 426 - 430, XP009064582 [X] 1-7,11-14,16,17,19 * Page 429, table 2, compounds 11j (CAS-RN 691858-68-1) and 14o (CAS-RN 691858-73-8). * DOI: http://dx.doi.org/10.1021/cc0340731 |