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Extract from the Register of European Patents

EP About this file: EP1772452

EP1772452 - Matrix metalloproteinase inhibitors and uses thereof [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  06.06.2008
Database last updated on 02.09.2024
Most recent event   Tooltip03.10.2008Change - representativepublished on 05.11.2008  [2008/45]
Applicant(s)For all designated states
Bristol-Myers Squibb Pharma Company
P.O. Box 4000
Princeton NJ 08543-4000 / US
[2008/37]
Former [2007/15]For all designated states
Bristol-Myers Squibb Pharma Company
PO Box 4000 Princeton
New Jersey 08443-4000 / US
Inventor(s)01 / Decicco, Carl P.
102 Indian Springs Road
Kennett Square, PA 19348 / US
02 / Nelson, David J.
40 Tiverton Circle
Newark, DE 19702 / US
03 / Barrett, John A.
46 Fox Run
Groton, MA 01450 / US
04 / Carpenter, Alan P.
73 Cranberry Hill Lane
Carlisle, MA 01741 / US
05 / Duran, James J.
17 Springbrook Lane
Newark, DE 19711 / US
06 / Rajopadhye, Milind
21 Honeysuckle Road
Wedstford, MA 01886 / US
 [2007/15]
Representative(s)Howard, Paul Nicholas, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2008/45]Howard, Paul Nicholas, et al
Carpmaels & Ransford 43-45 Bloomsbury Square
London WC1A 2RA / GB
Former [2007/15]Howard, Paul Nicholas, et al
Carpmaels & Ransford, 43-45 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date06076915.515.02.2001
[2007/15]
Priority number, dateUS20000182627P15.02.2000         Original published format: US 182627 P
[2007/15]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP1772452
Date:11.04.2007
Language:EN
[2007/15]
Type: A3 Search report 
No.:EP1772452
Date:04.07.2007
[2007/27]
Search report(s)(Supplementary) European search report - dispatched on:EP01.06.2007
ClassificationIPC:C07D413/12, C07D267/00, C07D401/12, C07D401/14, C07F9/09, A61K31/395, A61K31/4427, A61K31/661, A61K51/04, A61P35/00, A61P29/00
[2007/22]
CPC:
A61K49/14 (EP,US); A61K49/0002 (EP,US); A61K49/085 (EP,US);
A61K49/10 (EP,US); A61K51/088 (EP,US); A61P29/00 (EP);
A61P35/00 (EP); C07D207/26 (EP,US); C07D213/82 (EP,US);
C07D267/00 (EP,US); C07D401/12 (EP,US); C07D401/14 (EP,US);
C07D413/12 (EP,US); C07F9/6527 (EP,US) (-)
Former IPC [2007/15]C07D401/12, C07D413/12, C07D267/00, C07D401/14, C07F9/09, A61K31/395, A61K31/4427, A61K31/661, A61K51/04
Designated contracting states[2008/11]
Former [2007/15]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE,  TR 
TitleGerman:Matrix-Metalloproteinaseinhibitoren und deren Verwendung[2007/15]
English:Matrix metalloproteinase inhibitors and uses thereof[2007/15]
French:Inhibiteurs de métalloprotéase matricielle et utilisation de ceux-ci[2007/15]
Examination procedure05.01.2008Application deemed to be withdrawn, date of legal effect  [2008/28]
13.02.2008Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2008/28]
Parent application(s)   TooltipEP01912751.3  / EP1257549
Fees paidRenewal fee
23.10.2006Renewal fee patent year 03
23.10.2006Renewal fee patent year 04
23.10.2006Renewal fee patent year 05
23.10.2006Renewal fee patent year 06
23.10.2006Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
29.02.200808   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]EP0649658  (UNIV LELAND STANFORD JUNIOR [US]) [Y] 1,47,60,65-67,75-77 * the whole document *;
 [Y]WO9718207  (DU PONT MERCK PHARMA [US]) [Y] 1,4-8,10,20,28,29,47,48,51-56,60,61,68-74,78 * page 44, line 1 - page 48, line 20; example 1(k); table I; page 280, line 1 - page 281, line 30 *;
 [XY]WO9847541  (NYCOMED IMAGING AS [NO], et al) [X] 1,4-7,10,11,20,21,23,28,32,34,47,48,51-56,60,61,68-74,78 * pages 1-10, 25-28, 32-70; examples 1, 3 * * pages 1-10, 25-28, 32-70 * [Y] 1-10,20-22,24-31,33,35-38,47,48,51-56,60-78;
 [Y]WO9918074  (DU PONT PHARM CO [US]) [Y] 1,4-7,10,20,28,30,47,48,51-56,60,61,68-74,78 * page 4, line 14 - page 13, line 37; examples 65, 119; page 271, line 1 - page 272, line 22 *;
 [Y]WO9958162  (DU PONT PHARM CO [US]) [Y] 1,20-22,24,25,27,28,33,35,36,38,60-64 * page 73, line 25 - page 86, line 12; examples *;
 [Y]WO9965867  (DU PONT PHARM CO [US]) [Y] 1-7,9,10,20,28,31,47,48,51-56,60,61,68-74,78 * page 4, line 21 - page 19, line 35; table 8; page 176, line 1 - page 177, line 29 *;
 [Y]  - M. RAJOPADHYE ET AL, BIOORG. MED. CHEM. LETT., (1996), vol. 6, no. 15, pages 1737 - 1740, XP004135593 [Y] 1,20,21,26,28,37 * the whole document *

DOI:   http://dx.doi.org/10.1016/0960-894X(96)00264-8
 [X]  - MACPHERSON L J ET AL, "Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (199708), vol. 40, no. 16, ISSN 0022-2623, pages 2525 - 2532, XP002099324 [X] 1-79 * Tables 1 and 3 *

DOI:   http://dx.doi.org/10.1021/jm960871c
 [X]  - LEVY E ET AL, "Matrix Metalloproteinase Inhibitors: A Structure-Activity Study", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1998), vol. 41, no. 2, ISSN 0022-2623, pages 199 - 223, XP002115860 [X] 1-79 * Tables 2,8,10-15; Compounds 6a-6kkk *

DOI:   http://dx.doi.org/10.1021/jm970494j
 [X]  - BECKETT R P ET AL, "RECENT ADVANCES IN MATRIX METALLOPROTEINASE INHIBITOR RESEARCH", DDT - DRUG DISCOVERY TODAY, ELSEVIER SCIENCE LTD, GB, (199601), vol. 1, no. 1, ISSN 1359-6446, pages 16 - 26, XP002043033 [X] 1-79 * Compounds 1-2,7-9,11-17,21-25 *

DOI:   http://dx.doi.org/10.1016/1359-6446(96)89115-X
 [X]  - LOWE C, "Tumour necrosis factor-[alpha] antagonists and their therapeutic applications", EXPERT OPINION ON THERAPEUTIC PATENTS 1998 UNITED KINGDOM, (1998), vol. 8, no. 10, ISSN 1354-3776, pages 1309 - 1322, XP002430630 [X] 1-79 * compounds 18-41, 47; p. 1312-1315 *

DOI:   http://dx.doi.org/10.1517/13543776.8.10.1309
 [X]  - LEUNG D ET AL, "Protease inhibitors: Current status and future prospects", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (20000210), vol. 43, no. 3, ISSN 0022-2623, pages 305 - 341, XP002254336 [X] 1-79 * Point 5.4; compounds 128, 130-135, 138-141 *

DOI:   http://dx.doi.org/10.1021/jm990412m
 [X]  - BARLAAM B ET AL, "NEW ALPHA-SUBSTITUTED SUCCINATE-BASED HYDROXAMIC ACIDS AS TNFALPHA CONVERTASE INHIBITORS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1999), vol. 42, no. 23, ISSN 0022-2623, pages 4890 - 4908, XP000974275 [X] 1-79 * Compounds 1-6, 6a-6n, 12,22; tables 2-3 *

DOI:   http://dx.doi.org/10.1021/jm990377j
 [X]  - BECKETT R P ET AL, "Matrix metalloproteinase inhibitors 1998", EXPERT OPINION ON THERAPEUTIC PATENTS 1998 UNITED KINGDOM, (1998), vol. 8, no. 3, ISSN 1354-3776, pages 259 - 282, XP002430631 [X] 1-79 * Compounds 1-43,47-51 *

DOI:   http://dx.doi.org/10.1517/13543776.8.3.259
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.