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Extract from the Register of European Patents

EP About this file: EP1866283

EP1866283 - 4-FLUOROPHENYL-DERIVATIVES OF 1-{[1,5 -BIS (4-CHLOROPHENYL) -2-METHYL-1H-PYRROL-3-YL]METHYL} -4- METHYLPIPERAZINE, SYNTHESIS PROCESS AND USES THEREOF [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  25.06.2010
Database last updated on 28.09.2024
Most recent event   Tooltip25.06.2010Refusal of applicationpublished on 28.07.2010  [2010/30]
Applicant(s)For all designated states
Universita' Degli Studi di Siena
55, Via Banchi di Sotto
I-53100 Siena / IT
[2007/51]
Inventor(s)01 / BIAVA, Mariangela
c/o Università degli Studi di Roma "La Sapienza" P.le Aldo Moro,5
I-00185 Roma / IT
02 / MANETTI, Fabrizio
Università degli Studi di Siena Via Banchi di Sotto, 55
I-53100 Siena / IT
03 / DEIDDA, Delia
Via del Re, 101
I-40018 Gavaseto, San Pietro in Casale (BO), ITALY / IT
04 / POMPEI, Raffaello
Università degli Studi di Siena Via Banchi di Sotto, 55
I-53100 Siena / IT
05 / BOTTA, Maurizio
Università degli Studi di Siena Via Banchi di Sotto, 55
I-53100 Siena / IT
06 / PORRETTA, Giulio, Cesare
c/o Università degli Studi di Roma "La Sapienza" P.le Aldo Moro,5
I-00185 Roma / IT
 [2008/24]
Former [2007/51]01 / BIAVA, Mariangela
Università degli Studi di Siena Via Banchi di Sotto, 55
I-53100 Siena / IT
02 / MANETTI, Fabrizio
Università degli Studi di Siena Via Banchi di Sotto, 55
I-53100 Siena / IT
03 / DEIDDA, Delia
Università degli Studi di Siena Via Banchi di Sotto, 55
I-53100 Siena / IT
04 / POMPEI, Raffaello
Università degli Studi di Siena Via Banchi di Sotto, 55
I-53100 Siena / IT
05 / BOTTA, Maurizio
Università degli Studi di Siena Via Banchi di Sotto, 55
I-53100 Siena / IT
06 / PORRETTA, Giulio, Cesare
Università degli Studi di Siena Via Banchi di Sotto, 55
I-53100 Siena / IT
Representative(s)Capasso, Olga, et al
De Simone & Partners S.r.l.
Via Vincenzo Bellini, 20
00198 Roma / IT
[N/P]
Former [2007/51]Capasso, Olga, et al
de Simone & Partners S.p.A. Via Vincenzo Bellini, 20
00198 Roma / IT
Application number, filing date06711446.203.03.2006
[2007/51]
WO2006IT00131
Priority number, dateIT2005RM0009404.03.2005         Original published format: IT RM20050094
[2007/51]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2006092822
Date:08.09.2006
Language:EN
[2006/36]
Type: A2 Application without search report 
No.:EP1866283
Date:19.12.2007
Language:EN
The application published by WIPO in one of the EPO official languages on 08.09.2006 takes the place of the publication of the European patent application.
[2007/51]
Search report(s)International search report - published on:EP05.04.2007
ClassificationIPC:C07D207/32, A61K31/402, A61P31/06
[2007/51]
CPC:
C07D207/335 (EP,US); A61P31/06 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2007/51]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
YUNot yet paid
TitleGerman:4-FLUORPHENYLDERIVATE VON 1-{[1,5 -BIS(4-CHLORPHENYL)-2-METHYL-1H-PYRROL-3-YL]METHYL}-4-METHYLPIPERAZIN, SYNTHESEVERFAHREN UND ANWENDUNGEN DAVON[2007/51]
English:4-FLUOROPHENYL-DERIVATIVES OF 1-{[1,5 -BIS (4-CHLOROPHENYL) -2-METHYL-1H-PYRROL-3-YL]METHYL} -4- METHYLPIPERAZINE, SYNTHESIS PROCESS AND USES THEREOF[2007/51]
French:DERIVES DE 1-{[1,5-BIS(4-CHLOROPHENYL)-2-METHYL-1H-PYRROL-3-YL]METHYL}-4- EETHYLPIPERAZINE, SYNTHESE ET UTILISATIONS[2007/51]
Entry into regional phase24.09.2007National basic fee paid 
24.09.2007Designation fee(s) paid 
24.09.2007Examination fee paid 
Examination procedure24.09.2007Amendment by applicant (claims and/or description)
24.09.2007Examination requested  [2007/51]
25.03.2009Despatch of a communication from the examining division (Time limit: M04)
10.09.2009Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
20.11.2009Reply to a communication from the examining division
10.03.2010Despatch of communication that the application is refused, reason: substantive examination [2010/30]
20.03.2010Application refused, date of legal effect [2010/30]
Divisional application(s)EP09176606.3  / EP2172451
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
20.11.2009Request for further processing filed
20.11.2009Full payment received (date of receipt of payment)
Fees paidRenewal fee
20.03.2008Renewal fee patent year 03
09.09.2009Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.03.200904   M06   Fee paid on   09.09.2009
31.03.201005   M06   Not yet paid
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Cited inInternational search[X]JPS62178590  ;
 [IDY]  - BIAVA M ET AL, "Antimycobacterial compounds. Optimization of the BM 212 structure, the lead compound for a new pyrrole derivative class", BIOORGANIC & MEDICINAL CHEMISTRY, ELSEVIER SCIENCE LTD, GB, (2005), vol. 13, no. 4, ISSN 0968-0896, pages 1221 - 1230, XP004776026 [ID] 1-18 * available online: 02-12-2004;;; compounds 25-30 * [Y] 1,5-8,11,12

DOI:   http://dx.doi.org/10.1016/j.bmc.2004.11.018
 [X]  - PATENT ABSTRACTS OF JAPAN, (19880127), vol. 012, no. 028, Database accession no. (C - 471), & JP62178590 A 19870805 (TOYAMA CHEM CO LTD) [X] 1,5-8,11,12 * abstract *
 [Y]  - WERMUTH ET AL, "The Practise of Medicinal Chemistry", PRACTICE OF MEDICINAL CHEMISTRY, (1996), pages 203 - 237, XP002190259 [Y] 1,5-8,11,12 * page 211 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.