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EP1841771
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EP About this file: EP1841771
| EP1841771 - Diazabenzo[de]anthracen-3-one compounds and methods for inhibiting PARP [Right-click to bookmark this link] | |||
| Former [2007/41] | DIAZABENZOÝDE ̈ANTHRACEN-3-ONE COMPOUNDS AND METHODS FOR INHIBITING PARP | ||
| [2008/37] | Status | The application is deemed to be withdrawn Status updated on 09.09.2016 Database last updated on 10.07.2024 | Most recent event Tooltip | 09.09.2016 | Application deemed to be withdrawn | published on 12.10.2016 [2016/41] | Applicant(s) | For all designated states Eisai Inc. 100 Tice Boulevard Woodcliff Lake, NJ 07677 / US | [2010/02] |
| Former [2009/20] | For all designated states Eisai Corporation of North America 100 Tice Boulevard Woodcliff Lake, NJ 07677 / US | ||
| Former [2007/41] | For all designated states MGI GP, Inc. 6611 Tributary Street Baltimore, MD 21224 / US | Inventor(s) | 01 /
XU, Weizheng 3646 Grosvenor Drive Ellicot City, Maryland 21042 / US | 02 /
DELAHANTY, Greg 7801 Tucker Drive Nottingham, Maryland 21236 / US | 03 /
ZHANG, Jie 8513 High Timber Ct Ellicott City, Maryland 21043 / US | [2007/41] | Representative(s) | Stansfield, Kevin Eisai Europe Limited Legal - IP Department European Knowledge Centre Mosquito Way Hatfield, Herts AL10 9SN / GB | [2011/48] |
| Former [2011/17] | Schiweck, Weinzierl & Koch European Patent Attorneys Landsberger Straße 98 80339 München / DE | ||
| Former [2009/36] | Viering, Jentschura & Partner Postfach 22 14 43 80504 München / DE | ||
| Former [2007/41] | Viering, Jentschura & Partner Grillparzerstrasse 14 81675 München / DE | Application number, filing date | 06718756.7 | 19.01.2006 | [2007/41] | WO2006US01729 | Priority number, date | US20050644584P | 19.01.2005 Original published format: US 644584 P | US20050712140P | 30.08.2005 Original published format: US 712140 P | [2007/41] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2006078711 | Date: | 27.07.2006 | Language: | EN | [2006/30] | Type: | A2 Application without search report | No.: | EP1841771 | Date: | 10.10.2007 | Language: | EN | The application published by WIPO in one of the EPO official languages on 27.07.2006 takes the place of the publication of the European patent application. | [2007/41] | Search report(s) | International search report - published on: | US | 21.09.2006 | (Supplementary) European search report - dispatched on: | EP | 26.08.2008 | Classification | IPC: | C07D491/06, A61K31/5025, A61P9/00, A61P25/28, A61P29/00 | [2015/17] | CPC: |
C07D491/06 (EP,US);
A61K31/495 (EP,US);
A61K31/5025 (EP,US);
A61P1/04 (EP);
A61P13/12 (EP);
A61P17/00 (EP);
A61P19/02 (EP);
A61P19/06 (EP);
A61P19/10 (EP);
A61P21/00 (EP);
A61P25/00 (EP);
A61P25/02 (EP);
A61P25/04 (EP);
A61P25/24 (EP);
A61P25/28 (EP);
A61P27/02 (EP);
A61P29/00 (EP);
A61P3/10 (EP);
A61P31/04 (EP);
A61P31/18 (EP);
A61P35/00 (EP);
A61P35/02 (EP);
A61P37/04 (EP);
A61P39/02 (EP);
A61P41/00 (EP);
A61P43/00 (EP);
A61P9/00 (EP);
A61P9/10 (EP)
(-)
|
| Former IPC [2007/41] | C07D491/04, C07D498/04, A61K31/47, A61K31/50 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2007/41] | Extension states | AL | Not yet paid | BA | Not yet paid | HR | Not yet paid | MK | Not yet paid | YU | Not yet paid | Title | German: | Diazabenzo[de]anthracen-on-Verbindungen und Verfahren zur Hemmung von PARP | [2015/17] | English: | Diazabenzo[de]anthracen-3-one compounds and methods for inhibiting PARP | [2015/17] | French: | Composés de diazabenzo[de]anthracène-3-one et utilisation dans l'inhibition de PARP | [2015/17] |
| Former [2007/41] | DIAZABENZO[DE]ANTHRACEN-ON-VERBINDUNGEN UND VERFAHREN ZUR HEMMUNG VON PARP | ||
| Former [2007/41] | DIAZABENZOÝDE ̈ANTHRACEN-3-ONE COMPOUNDS AND METHODS FOR INHIBITING PARP | ||
| Former [2007/41] | COMPOSES DE DIAZABENZOÝDE ̈ANTHRACENE-3-ONE ET UTILISATION DANS L'INHIBITION DE PARP | Entry into regional phase | 26.07.2007 | National basic fee paid | 26.07.2007 | Search fee paid | 26.07.2007 | Designation fee(s) paid | 26.07.2007 | Examination fee paid | Examination procedure | 26.07.2007 | Examination requested [2007/41] | 23.01.2009 | Request for decision received: Application is deemed to be withdrawn | 12.02.2009 | Result of request for decision (Application is deemed to be withdrawn): Request accepted | 27.02.2009 | Despatch of a communication from the examining division (Time limit: M04) | 09.07.2009 | Reply to a communication from the examining division | 03.12.2010 | Despatch of a communication from the examining division (Time limit: M04) | 22.03.2011 | Reply to a communication from the examining division | 18.04.2012 | Despatch of a communication from the examining division (Time limit: M06) | 19.10.2012 | Reply to a communication from the examining division | 04.04.2014 | Despatch of a communication from the examining division (Time limit: M06) | 03.10.2014 | Reply to a communication from the examining division | 01.04.2015 | Communication of intention to grant the patent | 14.04.2016 | Application deemed to be withdrawn, date of legal effect [2016/41] | 23.05.2016 | Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2016/41] | Divisional application(s) | EP11156206.2 / EP2319847 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 27.02.2009 | Request for further processing for: | The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent | 06.11.2015 | Request for further processing filed | 06.11.2015 | Full payment received (date of receipt of payment) Request granted | 18.11.2015 | Decision despatched | Fees paid | Renewal fee | 26.07.2007 | Renewal fee patent year 03 | 30.01.2009 | Renewal fee patent year 04 | 25.01.2010 | Renewal fee patent year 05 | 25.01.2011 | Renewal fee patent year 06 | 25.01.2012 | Renewal fee patent year 07 | 25.01.2013 | Renewal fee patent year 08 | 27.01.2014 | Renewal fee patent year 09 | 27.01.2015 | Renewal fee patent year 10 | 27.01.2016 | Renewal fee patent year 11 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [DY]WO0116137 (GUILFORD PHARM INC [US], et al) [DY] 1-26 * pages 61-64; claims 1,5,16-53 *; | [D]US6291425 (LI JIA-HE [US], et al); | [Y]US6348475 (ZHANG JIE [US], et al) [Y] 1-3 * column 11, lines 1-25,50-55 * * column 12, lines 45-65 * * column 13, lines 20-25 * * abstract *; | [XY]WO2004105700 (GUILDFORD PHARMACEUTICALS INC [US], et al) [XY] 1-26 * claims 43-57 * | International search | [X]US6291425 (LI JIA-HE [US], et al) | by applicant | US5032617 | US5215738 | US5041653 | US5177075 | WO0042040 | WO0039070 | WO0039104 | WO9911623 | WO9911628 | WO9911622 | WO9959975 | WO9911644 | WO9911649 | WO9959973 | WO2004105700 | US2002028815 | US2003134843 | US2004067949 | WO9833802 | WO2005012305 | US6348475 | US6545011 | USRE36397E | US6380211 | US6235748 | US6121278 | US6197785 | US6380193 | US6346536 | US6514983 | US6306889 | US6387902 | US6201020 | US6291425 | US2005020595 | WO9613610 | WO9911645 | - CRISTOVAO ET AL., EFFECT OF A POLY(ADP-RIBOSE) POLYMERASE INHIBITOR ON DNA BREAKAGE AND CYTOTOXICITY INDUCED BY HYDROGEN PEROXIDE AND Y-RADIATION, (1996), vol. 16, pages 219 - 27 | - PLUMMER ET AL., CLIN. CANCER RES., (2005), vol. 11, no. 9, page 3402 | - KOCK ET AL., J. MED. CHEM., (2002), vol. 45, page 4961 | - WELTIN ET AL., "Effect of 6(5H)-Phenanthridinone, an Inhibitor of Poly(ADP-ribose) Polymerase, on Cultured Tumor Cells", ONCOL. RES., (1994), vol. 6, no. 9, pages 399 - 403 | - "Specific Inhibitors of Poly(ADP-Ribose) Synthetase and Mono(ADP-Ribosyl)-Transferase", J. BIOL. CHEM., (1992), vol. 267, no. 3, pages 1569 - 75 | - BANASIK ET AL., "Inhibitors and Activators of ADP-Ribosylation Reactions", MOLEC. CELL. BIOCHEM., (1994), vol. 138, doi:doi:10.1007/BF00928461, pages 185 - 97, XP009050157 DOI: http://dx.doi.org/10.1007/BF00928461 | - MILAM ET AL., "Inhibitors of Poly(Adenosine Diphosphate-Ribose) Synthesis; Effect on Other Metabolic Processes", SCIENCE, (1984), vol. 223, pages 589 - 91 | - LI; ZHANG, IDRUGS, (2001), vol. 4, no. 7, pages 804 - 812 | - WHITE AW ET AL., BIOORG. & MED. CHEM LETTS, (2004), vol. 14, page 2433 | - CANON KOCH SS ET AL., J. MED. CHEM., (2002), vol. 45, page 4961 | - SKALITSKY DJ ET AL., J. MED. CHEM., (2003), vol. 46, page 210 | - FARMER H ET AL., NATURE, (20050414), vol. 434, page 917 | - PLUMMER ER ET AL., CLIN. CANCER RES, (2005), vol. 11, no. 9, page 3402 | - TIKHE JG ET AL., J. MED. CHEM., (2004), vol. 47, page 5467 | - QUASTHOFF; HARTUNG, J. NEUROLOGY, (2002), vol. 249, pages 9 - 17 | - "Pharmaceutical Salts", J. PHARM. SCI., (1977), vol. 66, no. 1, pages 1 - 19 | - Burgers Medicinal Chemistry and Drug Chemistry, Fifth Ed,, (1995), vol. 1, pages 172-78 - 949-82 | - TENTORI L ET AL., "Systemic administration of the PARP- inhibitor GPI 15427 increases the anti-tumor activity of temozolomide against metastatic melanoma", MEDICAL SCIENCE MONITOR, (2003), vol. 9, no. 1, page 34 | - SUTO ET AL., "Dihydroiso-quinolinones: The Design and Synthesis of a New Series of Potent Inhibitors of Poly(ADP-ribose) Polymerase", ANTICANCER DRUG DES., (1991), vol. 6, pages 107 - 17 | - LINSKENS ET AL., NUCLEIC ACIDS RES., (1995), vol. 23, pages 3244 - 3251 | - WEST, ARCH. DERM., (1994), vol. 130, pages 87 - 95 | - TENTORI L. ET AL., "Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components", CANCER CHEMOTHER PHARMACOL., (2001), vol. 47, pages 361 - 9 | - CAVALETTI ET AL., "Protective Effects of glutathione on cisplatin neurotoxicity in rats", INT. J. RADIATION ONCOLOGY, (1994), vol. 29, pages 771 - 776, XP026849074 | - TREDICI ET AL., "Low-Dose Glutathione administration in the prevention of cisplatin-induced peripheral neuropathy in rats", NEURO TOXICOLOGY, (1994), vol. 15, pages 701 - 704 |