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Extract from the Register of European Patents

EP About this file: EP1926829

EP1926829 - LABELLED MODIFIED GUANINE-CONTAINING NUCLEOSIDES AND NUCLEOTIDES COMPRISING A FLUOROPHORE ATTACHED TO THE BASE THROUGH A LINKING GROUP COMPRISING A POLYETHYLENE GLYCOL SPACING GROUP AND METHODS FOR THEIR USE [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  16.06.2017
Database last updated on 11.09.2024
Most recent event   Tooltip16.06.2017Patent maintained (B2 publication)published on 19.07.2017  [2017/29]
Applicant(s)For all designated states
Illumina Cambridge Limited
Chesterford Research Park
Little Chesterford
Saffron Walden
Essex CB10 1XL / GB
[N/P]
Former [2017/29]For all designated states
Illumina Cambridge Limited
Chesterford Research Park Little Chesterford Saffron Walden
Essex CB10 1XL / GB
Former [2010/47]For all designated states
Illumina Cambridge Limited
Chesterford Research Park Little Chesterford Saffron Walden
Essex CB10 1XL / GB
Former [2008/23]For all designated states
Solexa Ltd.
Chesterford Research Park, Little Chesterford Saffron Walden
Essex CB10 1XL / GB
Inventor(s)01 / LIU, Xiaohai
c/o SOLEXA LIMITED
Chesterford Research Park
Little Chesterford
Saffron Walden
Essex CB10 1XL / GB
02 / MILTON, John
c/o SOLEXA LIMITED
Chesterford Research Park
Little Chesterford
Saffron Walden
Essex CB10 1XL / GB
 [2014/32]
Former [2008/23]01 / LIU, Xiaohai
c/o SOLEXA LIMITED Chesterford Research Park Little Chesterford Saffron Walden
Essex CB10 1XL / GB
02 / MILTON, John
c/o SOLEXA LIMITED Chesterford Research Park Little Chesterford Saffron Walden
Essex CB10 1XL / GB
Representative(s)Cooley (UK) LLP
22 Bishopsgate
London EC2N 4BQ / GB
[N/P]
Former [2017/29]Cooley (UK) LLP
Dashwood
69 Old Broad Street
London EC2M 1QS / GB
Former [2014/32]Barnes, Colin Lloyd
Stratagem IPM Limited
Forsters Wing, Anstey Hall
Maris Lane
Trumpington
Cambridge CB2 9LG / GB
Former [2010/47]Barnes, Colin Lloyd
Stratagem IPM Limited Forsters Wing, Anstey Hall Maris Lane Trumpington
Cambridge CB2 9LG / GB
Former [2008/23]White, Nina Louise
Boult Wade Tennant Verulam Gardens 70 Gray's Inn Road
London WC1X 8BT / GB
Application number, filing date06779167.318.08.2006
[2008/23]
WO2006GB03095
Priority number, dateGB2005001709719.08.2005         Original published format: GB 0517097
[2008/23]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007020457
Date:22.02.2007
Language:EN
[2007/08]
Type: A2 Application without search report 
No.:EP1926829
Date:04.06.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 22.02.2007 takes the place of the publication of the European patent application.
[2008/23]
Type: B1 Patent specification 
No.:EP1926829
Date:06.08.2014
Language:EN
[2014/32]
Type: B2 New European patent specification 
No.:EP1926829
Date:19.07.2017
Language:EN
[2017/29]
Search report(s)International search report - published on:EP25.10.2007
ClassificationIPC:C07H19/16, C07H19/20, C07H21/00, C12Q1/68
[2014/10]
CPC:
C12Q1/686 (EP,US)
C-Set:
C12Q1/686, C12Q2525/113 (EP,US)
Former IPC [2008/23]C12Q1/68
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2017/29]
Former [2008/23]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:MARKIERTE MODIFIZIERTE GUANIN-ENTHALTENDEN NUKLEOSIDEN UND NUKLEOTIDEN MIT KOVALENT GEBUNDENEN FLUOROPHOR AN DER BASE WOBEI DIE VERBINDENDE LINKER-KOMPONENTE POLYETHYLENGLYKOL-EINHEITEN ENTHÄLT UND METHODEN ZU DEREN ANWENDUNG[2014/10]
English:LABELLED MODIFIED GUANINE-CONTAINING NUCLEOSIDES AND NUCLEOTIDES COMPRISING A FLUOROPHORE ATTACHED TO THE BASE THROUGH A LINKING GROUP COMPRISING A POLYETHYLENE GLYCOL SPACING GROUP AND METHODS FOR THEIR USE[2008/23]
French:NUCLEOSIDES ET NUCLEOTIDES MARQUÉS CONTENANT DES GUANINES MODIFIÉES ET UN FLUOROPHORE FIXÉ À LA BASE PAR L'INTERMÉDIAIRE D'UN GROUPE DE LIAISON POLYALKYLÈNEGLYCOL[2008/23]
Former [2008/23]MARKIERTE MODIFIZIERTE GUANINHALTIGE NUKLEOSIDE UND NUKLEOTIDE MIT EINEM AN DIE BASE ÜBER EINE EINE POLYETHYLENGLYKOL-ABSTANDHALTERGRUPPE ENTHALTENDE VERKNÜPFUNGSGRUPPE GEBUNDENEN FLUOROPHOR
Entry into regional phase05.02.2008National basic fee paid 
05.02.2008Designation fee(s) paid 
05.02.2008Examination fee paid 
Examination procedure05.02.2008Examination requested  [2008/23]
13.05.2008Amendment by applicant (claims and/or description)
06.06.2008Despatch of communication of loss of particular rights: Claims {1}
04.04.2013Despatch of a communication from the examining division (Time limit: M04)
17.07.2013Reply to a communication from the examining division
05.03.2014Communication of intention to grant the patent
27.06.2014Fee for grant paid
27.06.2014Fee for publishing/printing paid
27.06.2014Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  04.04.2013
Opposition(s)Opponent(s)01  28.04.2015    ADMISSIBLE
Kilger, Christian
Wachtelstr. 4
14195 Berlin / DE
Opponent's representative
CH Kilger Anwaltspartnerschaft mbB
Fasanenstraße 29
10719 Berlin / DE
 [N/P]
Former [2015/23]
Opponent(s)01  28.04.2015    ADMISSIBLE
Kilger, Christian
Wachtelstr. 4
14195 Berlin / DE
Opponent's representative
CH Kilger Anwaltspartnerschaft mbB
Fasanenstrasse 29
10719 Berlin / DE
12.06.2015Invitation to proprietor to file observations on the notice of opposition
28.09.2015Reply of patent proprietor to notice(s) of opposition
22.11.2016Legal effect of interlocutory decision in opposition
22.11.2016Date of oral proceedings
12.12.2016Despatch of interlocutory decision in opposition
12.12.2016Despatch of minutes of oral proceedings
13.04.2017Despatch of communication that the patent will be maintained as amended
08.06.2017Fee for printing new specification paid
Request for further processing for:Loss of rights: Claims
02.07.2008Request for further processing filed
02.07.2008Full payment received (date of receipt of payment)
Request granted
15.07.2008Decision despatched
Fees paidRenewal fee
28.03.2008Renewal fee patent year 03
12.08.2009Renewal fee patent year 04
17.08.2010Renewal fee patent year 05
11.08.2011Renewal fee patent year 06
10.08.2012Renewal fee patent year 07
19.08.2013Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.08.2006
AT06.08.2014
BE06.08.2014
CY06.08.2014
CZ06.08.2014
DK06.08.2014
EE06.08.2014
ES06.08.2014
FI06.08.2014
IT06.08.2014
LT06.08.2014
LV06.08.2014
MC06.08.2014
NL06.08.2014
PL06.08.2014
RO06.08.2014
SE06.08.2014
SI06.08.2014
SK06.08.2014
TR06.08.2014
IE18.08.2014
LU18.08.2014
CH31.08.2014
LI31.08.2014
BG06.11.2014
GR07.11.2014
IS06.12.2014
PT09.12.2014
[2016/33]
Former [2016/32]HU18.08.2006
AT06.08.2014
BE06.08.2014
CY06.08.2014
CZ06.08.2014
DK06.08.2014
EE06.08.2014
ES06.08.2014
FI06.08.2014
IT06.08.2014
LT06.08.2014
LV06.08.2014
MC06.08.2014
NL06.08.2014
PL06.08.2014
RO06.08.2014
SE06.08.2014
SI06.08.2014
SK06.08.2014
IE18.08.2014
CH31.08.2014
LI31.08.2014
BG06.11.2014
GR07.11.2014
IS06.12.2014
PT09.12.2014
Former [2015/50]AT06.08.2014
CY06.08.2014
CZ06.08.2014
DK06.08.2014
EE06.08.2014
ES06.08.2014
FI06.08.2014
IT06.08.2014
LT06.08.2014
LV06.08.2014
MC06.08.2014
NL06.08.2014
PL06.08.2014
RO06.08.2014
SE06.08.2014
SI06.08.2014
SK06.08.2014
IE18.08.2014
BE31.08.2014
CH31.08.2014
LI31.08.2014
BG06.11.2014
GR07.11.2014
IS06.12.2014
PT09.12.2014
Former [2015/37]AT06.08.2014
CY06.08.2014
CZ06.08.2014
DK06.08.2014
EE06.08.2014
ES06.08.2014
FI06.08.2014
IT06.08.2014
LT06.08.2014
LV06.08.2014
MC06.08.2014
NL06.08.2014
PL06.08.2014
RO06.08.2014
SE06.08.2014
SK06.08.2014
IE18.08.2014
BE31.08.2014
CH31.08.2014
LI31.08.2014
BG06.11.2014
GR07.11.2014
IS06.12.2014
PT09.12.2014
Former [2015/27]AT06.08.2014
CY06.08.2014
CZ06.08.2014
DK06.08.2014
EE06.08.2014
ES06.08.2014
FI06.08.2014
IT06.08.2014
LT06.08.2014
LV06.08.2014
MC06.08.2014
NL06.08.2014
PL06.08.2014
RO06.08.2014
SE06.08.2014
SK06.08.2014
BE31.08.2014
CH31.08.2014
LI31.08.2014
BG06.11.2014
GR07.11.2014
IS06.12.2014
PT09.12.2014
Former [2015/23]AT06.08.2014
CY06.08.2014
CZ06.08.2014
DK06.08.2014
EE06.08.2014
ES06.08.2014
FI06.08.2014
IT06.08.2014
LT06.08.2014
LV06.08.2014
NL06.08.2014
PL06.08.2014
RO06.08.2014
SE06.08.2014
SK06.08.2014
BE31.08.2014
CH31.08.2014
LI31.08.2014
BG06.11.2014
GR07.11.2014
IS06.12.2014
PT09.12.2014
Former [2015/22]AT06.08.2014
CY06.08.2014
DK06.08.2014
ES06.08.2014
FI06.08.2014
IT06.08.2014
LT06.08.2014
LV06.08.2014
NL06.08.2014
PL06.08.2014
RO06.08.2014
SE06.08.2014
BE31.08.2014
CH31.08.2014
LI31.08.2014
BG06.11.2014
GR07.11.2014
IS06.12.2014
PT09.12.2014
Former [2015/20]AT06.08.2014
CY06.08.2014
ES06.08.2014
FI06.08.2014
LT06.08.2014
LV06.08.2014
NL06.08.2014
PL06.08.2014
SE06.08.2014
BE31.08.2014
CH31.08.2014
LI31.08.2014
BG06.11.2014
GR07.11.2014
IS06.12.2014
PT09.12.2014
Former [2015/19]AT06.08.2014
CY06.08.2014
ES06.08.2014
FI06.08.2014
LT06.08.2014
LV06.08.2014
NL06.08.2014
PL06.08.2014
SE06.08.2014
BE31.08.2014
BG06.11.2014
GR07.11.2014
IS06.12.2014
PT09.12.2014
Former [2015/12]AT06.08.2014
CY06.08.2014
ES06.08.2014
FI06.08.2014
LT06.08.2014
LV06.08.2014
NL06.08.2014
PL06.08.2014
SE06.08.2014
BG06.11.2014
GR07.11.2014
IS06.12.2014
PT09.12.2014
Former [2015/11]CY06.08.2014
ES06.08.2014
FI06.08.2014
LT06.08.2014
PL06.08.2014
SE06.08.2014
BG06.11.2014
GR07.11.2014
PT09.12.2014
Former [2015/10]ES06.08.2014
FI06.08.2014
LT06.08.2014
SE06.08.2014
BG06.11.2014
Former [2015/09]FI06.08.2014
LT06.08.2014
SE06.08.2014
Former [2015/08]LT06.08.2014
Cited inInternational search[DA]WO2004018493  (SOLEXA LTD [GB], et al) [DA] 1-17 * abstract * * page 20, line 3 - page 21, line 35 * * page 50, lines 10-14 *;
 [A]US6380378  (KITAMURA AKINORI [JP], et al) [A] 1-17 * column 16, line 34 - column 17, line 27 *;
 [E]WO2007015168  (DAKO DENMARK AS [DK], et al) [E] 1-17 * page 57; example 6; sequence AD * * claim 25 * * pages 2-4, paragraphs 7-10 * * pages 6-9, paragraphs 23,24; compounds I-V * * page 14, lines 16-19 * * page 28, paragraph 72 * * pages 29-30, paragraph 77 * * pages 53-54; example 4 *;
 [E]WO2006097320  (GENOVOXX GMBH [DE], et al) [E] 1-17 * page 79; figures 14,28,29; example 19 * * page 80; example 21 * * pages 81-83; figures 14,31A,31B; example 23 * * pages 98-99; figures 14,42A; example 36 * * page 12, lines 30-33 *
 [DA]  - TORIMURA M ET AL, "FLUORESCENCE-QUENCHING PHENOMENON BY PHOTOINDUCED ELECTRON TRANSFER BETWEEN A FLUORESCENT DYE AND A NUCLEOTIDE BASE", ANALYTICAL SCIENCES, JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY, TOKYO,, JP, (200101), vol. 17, no. 1, ISSN 0910-6340, pages 155 - 160, XP002953171 [DA] 1-17 * the whole document * * page 158, column LEFT, paragraph LAST; table 3 *

DOI:   http://dx.doi.org/10.2116/analsci.17.155
 [DA]  - KURATA S ET AL, "Fluorescent quenching-based quantitative detection of specific DNA/RNA using a BODIPY((R)) FL-labeled probe or primer", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, (20010315), vol. 29, no. 6, ISSN 0305-1048, page E34, XP002376104 [DA] 1-17 * abstract * * page 3, column LEFT, paragraph SECOND *

DOI:   http://dx.doi.org/10.1093/nar/29.6.e34
by applicant   - WELCH ET AL., CHEM. EUR. J., (1999), vol. 5, no. 3, pages 951 - 960
OppositionWO2004048397
 WO2004031405
 WO03087302
 WO2005044836
    - RANDOLPH J.B. ET AL, "Stability, specificity and fluorescence brightness of multiply-labeled fluorescent DNA probes", NUCLEIC ACIDS RESEARCH, (1997), vol. 25, no. 14, doi:doi:10.1093/nar/25.14.2923, pages 2923 - 2929, XP002074426

DOI:   http://dx.doi.org/10.1093/nar/25.14.2923
    - SEIDEL C.A.M. ET AL, "Nucleobase-specific quenching of fluorescent dyes. 1. Nucleobase one-electron redox potentials aqnd their correlation with static and dynamic quenching efficiencies", J. PHYS. CHEM., (1996), vol. 100, pages 5541 - 5553
    - BEHLKE M.A. ET AL, "Fluorescence quenching by proximal G-bases", IDT TECHNICAL BULLETIN, (2005), pages 1 - 3
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.