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Extract from the Register of European Patents

EP About this file: EP1925941

EP1925941 - METHOD FOR PREDICTION OF THE EFFICACY OF VASCULARIZATION INHIBITOR [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  04.10.2013
Database last updated on 09.07.2024
Most recent event   Tooltip01.07.2016Lapse of the patent in a contracting state
New state(s): IS		published on 03.08.2016  [2016/31]
Applicant(s)For all designated states
Eisai R&D Management Co., Ltd.
6-10, Koishikawa 4-chome, Bunkyo-ku
Tokyo 112-8088 / JP
[2008/22]
Inventor(s)01 / MATSUI, Junji, c/o EISAI CO., LTD.
Tsukuba Research Lab.
1-3, Tokodai 5-chome
Tsukuba-shi, Ibaraki 300-2635 / JP
02 / SEMBA, Taro, c/o EISAI CO., LTD.
Tsukuba Research Lab.
1-3, Tokodai 5-chome
Tsukuba-shi, Ibaraki 3000-2635 / JP
 [2012/48]
Former [2008/22]01 / MATSUI, Junji, c/o EISAI CO., LTD.
Tsukuba Research Lab., 1-3, Tokodai 5-chome
Tsukuba-shi, Ibaraki 300-2635 / JP
02 / SEMBA, Taro, c/o EISAI CO., LTD.
Tsukuba Research Lab., 1-3, Tokodai 5-chome
Tsukuba-shi, Ibaraki 3000-2635 / JP
Representative(s)Woods, Geoffrey Corlett
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[2012/48]
Former [2008/22]Woods, Geoffrey Corlett
J.A. KEMP & CO. Gray's Inn 14 South Square
London WC1R 5JJ / GB
Application number, filing date06782407.801.08.2006
[2008/22]
WO2006JP315563
Priority number, dateJP2005022344001.08.2005         Original published format: JP 2005223440
[2008/22]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007015569
Date:08.02.2007
Language:JA
[2007/06]
Type: A1 Application with search report 
No.:EP1925941
Date:28.05.2008
Language:EN
[2008/22]
Type: B1 Patent specification 
No.:EP1925941
Date:28.11.2012
Language:EN
[2012/48]
Search report(s)International search report - published on:JP08.02.2007
(Supplementary) European search report - dispatched on:EP23.07.2010
ClassificationIPC:G01N33/574, A61K31/404, A61K31/47, A61K39/395, A61K45/00, A61P35/00, C12Q1/68, G01N33/15, G01N33/50, C12N15/09
[2008/22]
CPC:
G01N33/57484 (EP,US); A61P35/00 (EP); A61P43/00 (EP);
C12Q1/6886 (EP,US); G01N33/5023 (EP,US); C12Q2600/106 (EP,US);
C12Q2600/158 (EP,US); G01N2333/70503 (EP,US); G01N2800/44 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/22]
Extension statesAL27.02.2008
BA27.02.2008
HR27.02.2008
MK27.02.2008
RS27.02.2008
TitleGerman:VERFAHREN ZUR VORHERSAGE DER WIRKSAMKEIT EINES VASKULARISIERUNGSINHIBITORS[2008/22]
English:METHOD FOR PREDICTION OF THE EFFICACY OF VASCULARIZATION INHIBITOR[2008/22]
French:PROCÉDÉ DE PRÉDICTION DE L'EFFICACITÉ D'UN INHIBITEUR DE VASCULARISATION[2008/22]
Entry into regional phase27.02.2008Translation filed 
27.02.2008National basic fee paid 
27.02.2008Search fee paid 
27.02.2008Designation fee(s) paid 
27.02.2008Examination fee paid 
Examination procedure27.02.2008Examination requested  [2008/22]
10.11.2010Amendment by applicant (claims and/or description)
29.09.2011Despatch of a communication from the examining division (Time limit: M04)
23.01.2012Reply to a communication from the examining division
20.06.2012Communication of intention to grant the patent
16.10.2012Fee for grant paid
16.10.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  29.09.2011
Opposition(s)29.08.2013No opposition filed within time limit [2013/45]
Fees paidRenewal fee
14.08.2008Renewal fee patent year 03
12.08.2009Renewal fee patent year 04
17.08.2010Renewal fee patent year 05
11.08.2011Renewal fee patent year 06
23.08.2012Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU01.08.2006
AT28.11.2012
BE28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
IS28.11.2012
IT28.11.2012
LT28.11.2012
LV28.11.2012
MC28.11.2012
NL28.11.2012
PL28.11.2012
RO28.11.2012
SE28.11.2012
SI28.11.2012
SK28.11.2012
TR28.11.2012
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
IE01.08.2013
LU01.08.2013
[2016/31]
Former [2015/34]HU01.08.2006
AT28.11.2012
BE28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
IT28.11.2012
LT28.11.2012
LV28.11.2012
MC28.11.2012
NL28.11.2012
PL28.11.2012
RO28.11.2012
SE28.11.2012
SI28.11.2012
SK28.11.2012
TR28.11.2012
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
IE01.08.2013
LU01.08.2013
Former [2015/32]AT28.11.2012
BE28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
IT28.11.2012
LT28.11.2012
LV28.11.2012
MC28.11.2012
NL28.11.2012
PL28.11.2012
RO28.11.2012
SE28.11.2012
SI28.11.2012
SK28.11.2012
TR28.11.2012
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
IE01.08.2013
Former [2014/33]AT28.11.2012
BE28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
IT28.11.2012
LT28.11.2012
LV28.11.2012
MC28.11.2012
NL28.11.2012
PL28.11.2012
RO28.11.2012
SE28.11.2012
SI28.11.2012
SK28.11.2012
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
IE01.08.2013
Former [2014/20]AT28.11.2012
BE28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
IT28.11.2012
LT28.11.2012
LV28.11.2012
MC28.11.2012
NL28.11.2012
PL28.11.2012
RO28.11.2012
SE28.11.2012
SI28.11.2012
SK28.11.2012
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/37]AT28.11.2012
BE28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
IT28.11.2012
LT28.11.2012
LV28.11.2012
NL28.11.2012
PL28.11.2012
RO28.11.2012
SE28.11.2012
SI28.11.2012
SK28.11.2012
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/35]AT28.11.2012
BE28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SE28.11.2012
SI28.11.2012
SK28.11.2012
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/34]AT28.11.2012
BE28.11.2012
CY28.11.2012
DK28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SE28.11.2012
SI28.11.2012
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/31]AT28.11.2012
BE28.11.2012
CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SE28.11.2012
SI28.11.2012
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/28]BE28.11.2012
CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SE28.11.2012
SI28.11.2012
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/27]BE28.11.2012
CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SE28.11.2012
SI28.11.2012
GR01.03.2013
ES11.03.2013
Former [2013/26]CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SE28.11.2012
SI28.11.2012
GR01.03.2013
ES11.03.2013
Former [2013/24]CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SE28.11.2012
GR01.03.2013
ES11.03.2013
Former [2013/23]CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SE28.11.2012
ES11.03.2013
Former [2013/22]FI28.11.2012
LT28.11.2012
SE28.11.2012
ES11.03.2013
Former [2013/21]LT28.11.2012
SE28.11.2012
Former [2013/20]LT28.11.2012
Documents cited:Search[XY]  - BENJAMIN L E ET AL, "Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal.", THE JOURNAL OF CLINICAL INVESTIGATION JAN 1999 LNKD- PUBMED:9916127, (199901), vol. 103, no. 2, ISSN 0021-9738, pages 159 - 165, XP009133357 [X] 1-3 * Whole document;;; figure 2 * [Y] 4-9
 [Y]  - BERGERS GABRIELE ET AL, "Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors", JOURNAL OF CLINICAL INVESTIGATION, AMERICAN SOCIETY FOR CLINICAL INVESTIGATION, US LNKD- DOI:10.1172/JCI200317929, (20030501), vol. 111, no. 9, ISSN 0021-9738, pages 1287 - 1295, XP002317731 [Y] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1172/JCI200317929
 [Y]  - ERBER RALF ET AL, "Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms", FASEB JOURNAL, FED. OF AMERICAN SOC. FOR EXPERIMENTAL BIOLOGY, US, vol. 18, no. 2, ISSN 0892-6638, (20041204), pages 338 - 340, (20091001), XP002548466 [Y] 1-9 * the whole document *
 [Y]  - MCCARTY MARYA F ET AL, "ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor with additional activity against epidermal growth factor receptor tyrosine kinase, inhibits orthotopic growth and angiogenesis of gastric cancer.", MOLECULAR CANCER THERAPEUTICS SEP 2004 LNKD- PUBMED:15367698, (200409), vol. 3, no. 9, ISSN 1535-7163, pages 1041 - 1048, XP009133243 [Y] 1-9 * Discussion *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.