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Extract from the Register of European Patents

EP About this file: EP1907610

EP1907610 - SECRETION OF ANTIBODIES WITHOUT SIGNAL PEPTIDES FROM BACTERIA [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.07.2014
Database last updated on 10.07.2024
Most recent event   Tooltip15.07.2016Lapse of the patent in a contracting state
New state(s): TR		published on 17.08.2016  [2016/33]
Applicant(s)For all designated states
Kalobios Pharmaceuticals, Inc.
3427 Hillview Avenue
Palo Alto, CA 94304 / US
[2008/15]
Inventor(s)01 / YARRANTON, Geoffrey
1148 Balboa Avenue
Burlingame, CA 94010 / US
02 / BEBBINGTON, Christopher, R.
132 Avila Road
San Mateo, CA 94402 / US
 [2008/15]
Representative(s)Müller-Boré & Partner Patentanwälte PartG mbB
Friedenheimer Brücke 21
80639 München / DE
[N/P]
Former [2013/37]Müller-Boré & Partner Patentanwälte
Grafinger Strasse 2
81671 München / DE
Former [2010/26]Müller-Boré & Partner Patentanwälte
Grafinger Strasse 2
81671 München / DE
Former [2008/15]Hill, Justin John, et al
McDermott Will & Emery UK LLP 7 Bishopsgate
London EC2N 3AR / GB
Application number, filing date06786474.407.07.2006
[2008/15]
WO2006US26334
Priority number, dateUS20050701902P22.07.2005         Original published format: US 701902 P
US2005027390614.11.2005         Original published format: US 273906
[2008/15]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007018853
Date:15.02.2007
Language:EN
[2007/07]
Type: A2 Application without search report 
No.:EP1907610
Date:09.04.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 15.02.2007 takes the place of the publication of the European patent application.
[2008/15]
Type: B1 Patent specification 
No.:EP1907610
Date:11.09.2013
Language:EN
[2013/37]
Search report(s)International search report - published on:US16.04.2009
(Supplementary) European search report - dispatched on:EP24.11.2009
ClassificationIPC:C12Q1/70, C12P21/06, C12P21/04, C12N7/00, C12N15/00, A61K39/395, C12P21/08
[2009/30]
CPC:
C07K16/00 (EP,US); C07K16/18 (KR); A61K39/395 (KR);
C07H21/04 (KR); C07K16/1214 (EP,US); C12P21/06 (KR);
C07K2317/21 (EP,US); C07K2317/55 (EP,US) (-)
Former IPC [2008/15]C40B30/06, C40B40/10, A61K39/395, C07K16/18, C07H21/04, C12P21/06, C12N15/74, C12N1/21
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/15]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:SEKRETION VON ANTIKÖRPERN OHNE SIGNALPEPTIDE AUS BAKTERIEN[2008/15]
English:SECRETION OF ANTIBODIES WITHOUT SIGNAL PEPTIDES FROM BACTERIA[2008/15]
French:SECRETION D'ANTICORPS SANS PEPTIDES DE SIGNAL DE BACTERIE[2008/15]
Entry into regional phase22.01.2008National basic fee paid 
22.01.2008Search fee paid 
22.01.2008Designation fee(s) paid 
22.01.2008Examination fee paid 
Examination procedure22.01.2008Examination requested  [2008/15]
09.03.2010Despatch of a communication from the examining division (Time limit: M04)
06.07.2010Reply to a communication from the examining division
27.07.2010Despatch of a communication from the examining division (Time limit: M04)
03.11.2010Reply to a communication from the examining division
19.05.2011Despatch of a communication from the examining division (Time limit: M06)
19.10.2011Reply to a communication from the examining division
27.08.2012Despatch of a communication from the examining division (Time limit: M04)
25.10.2012Reply to a communication from the examining division
12.11.2012Despatch of a communication from the examining division (Time limit: M02)
09.01.2013Reply to a communication from the examining division
06.03.2013Communication of intention to grant the patent
13.06.2013Fee for grant paid
13.06.2013Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  09.03.2010
Opposition(s)12.06.2014No opposition filed within time limit [2014/34]
Fees paidRenewal fee
22.01.2008Renewal fee patent year 03
28.07.2009Renewal fee patent year 04
29.07.2010Renewal fee patent year 05
28.07.2011Renewal fee patent year 06
30.07.2012Renewal fee patent year 07
31.07.2013Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU07.07.2006
AT11.09.2013
BE11.09.2013
BG11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
MC11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
TR11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
[2016/33]
Former [2016/32]HU07.07.2006
AT11.09.2013
BE11.09.2013
BG11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
MC11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
Former [2016/25]AT11.09.2013
BE11.09.2013
BG11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
MC11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
Former [2016/21]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
MC11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
Former [2014/41]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
Former [2014/28]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
Former [2014/24]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
Former [2014/23]BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
Former [2014/22]BE11.09.2013
CY11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
GR12.12.2013
Former [2014/18]BE11.09.2013
CY11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
SE11.09.2013
SI11.09.2013
GR12.12.2013
Former [2014/12]CY03.07.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
SE11.09.2013
SI11.09.2013
GR12.12.2013
Former [2014/11]CY03.07.2013
FI11.09.2013
LT11.09.2013
SE11.09.2013
Former [2014/10]CY03.07.2013
LT11.09.2013
SE11.09.2013
Former [2014/09]LT11.09.2013
SE11.09.2013
Former [2014/08]LT11.09.2013
Documents cited:Search[Y]  - PRINZ WILLIAM A ET AL, "Targeting of signal sequenceless proteins for export in Escherichia coli with altered protein translocase", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, (1996), vol. 15, no. 19, ISSN 0261-4189, pages 5209 - 5217, XP002551638 [Y] 1-32 * see the whole document *
 [PY]  - SMITH MARGARET A ET AL, "Modeling the effects of prl mutations on the Escherichia coli SecY complex", JOURNAL OF BACTERIOLOGY, (200509), vol. 187, no. 18, ISSN 0021-9193, pages 6454 - 6465, XP002551639 [PY] 1-32 * see the whole document *

DOI:   http://dx.doi.org/10.1128/JB.187.18.6454-6465.2005
 [A]  - BOST S ET AL, "Prl mutations in the Escherichia coli secG gene", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM, US, (19970214), vol. 272, no. 7, ISSN 0021-9258, pages 4087 - 4093, XP002498922

DOI:   http://dx.doi.org/10.1074/jbc.272.7.4087
 [A]  - KHATIB KARIM ET AL, "A novel class of secA alleles that exert a signal-sequence-dependent effect on protein export in Escherichia coli.", GENETICS, (200211), vol. 162, no. 3, ISSN 0016-6731, pages 1031 - 1043, XP002551640
 [A]  - MALLIK IPSITA ET AL, "Recognition of secretory proteins in Escherichia coli requires signals in addition to the signal sequence and slow folding", BMC MICROBIOLOGY, BIOMED CENTRAL, LONDON, GB, (20021111), vol. 2, no. 1, ISSN 1471-2180, page 32, XP021014813

DOI:   http://dx.doi.org/10.1186/1471-2180-2-32
International search[Y]US5843685  (BETTER MARC D [US], et al);
 [Y]  - DERMAN A.I. ET AL., "A Signal Sequence is not Required for Protein Export in prlA Mutants of Escherichia coli.", THE EMBO JOURNAL., (1993), vol. 12, no. 3, pages 879 - 888, XP008124955
 [Y]  - PEREZ-PEREZ ET AL., "Increasing the Efficiency of Protein Export in Escherichia coli.", BIOTECHNOLOGY., (19940212), vol. 12, no. 2, pages 178 - 180, XP002056063

DOI:   http://dx.doi.org/10.1038/nbt0294-178
 [Y]  - PEREZ-PEREZ ET AL., "Different PrlA Proteins Increase the Efficiency of Periplasmic Production of Human Interleukin-6 in Escherichia coli.", JOURNAL OF BIOTECHNOLOGY., (19960820), vol. 49, no. 1-3, pages 245 - 247, XP004037113

DOI:   http://dx.doi.org/10.1016/0168-1656(96)83990-3
 [Y]  - LISS L.R. ET AL, "Export Defect Adjacent to the Processing Site of Staphylococcal Nuclease is Suppressed by a prlA Mutation.", JOURNAL OF BACTERIOLOGY., (198511), vol. 164, no. 2, pages 925 - 928, XP008124946
Examination   - DALEY ET AL., "Application of monoclonal antibodies in functional and comparative investigations of heavy-chain immunoglobulins in new world camelids", CLIN. AND DIAG. LAB. IMMUNOL., (2005), vol. 12, no. 3, pages 380 - 386
by applicantUS2004266993
    - CLARKE ET AL., STRUCTURE FOLD. DES., (1999), vol. 7, pages 1145 - 53
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.