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EP About this file: EP2049482

EP2049482 - POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF ARYL- AND HETEROARYLACETIC ACIDS WITH VERY FAST SKIN PENETRATION RATE [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 26.08.2016 Database last updated on 02.11.2024
Most recent event Tooltip	17.08.2018	Lapse of the patent in a contracting state New state(s): BG	published on 19.09.2018 [2018/38]
Applicant(s)	For all designated states Techfields Biochem Co. Ltd Techfields Biochem 2399 Jinqiu Road 129 Shanghai N/A 200444 / CN
	For all designated states Yu, Chongxi Techfields Biochem 12952 Stockton Avenue Plainfield, Illinois 60585 / US
	[2009/17]
Inventor(s)	01 / YU, Chongxi TECHFIELDS BIOCHEM 12952 Stockton Ave. Plainfield Illinois 60585 / US
	02 / XU, Lina TECHFIELDS BIOCHEM CO. LTD. 2399 Jinqiu Road, No. 129 Shanghai N/a 200444 / CN
	[2015/43]
Former [2009/17]	01 / YU, Chongxi TECHFIELDS BIOCHEM 12952 Stockton Ave. Plainfield Illinois 60585 / US
	02 / XU, Lina TECHFIELDS BIOCHEM CO. LTD. 2399 Jinqiu Road, No. 129 Shanghai N/a 200444 / CN
Representative(s)	Finnegan Europe LLP 1 London Bridge London SE1 9BG / GB
	[N/P]
Former [2015/43]	Viering, Jentschura & Partner Patent- und Rechtsanwälte Kennedydamm 55 / Roßstrasse 40476 Düsseldorf / DE
Former [2012/19]	Viering, Jentschura & Partner Kennedydamm 55/Roßstr. 40476 Düsseldorf / DE
Former [2009/30]	Viering, Jentschura & Partner Postfach 22 14 43 80504 München / DE
Former [2009/17]	Viering, Jentschura & Partner Grillparzerstrasse 14 81675 München / DE
Application number, filing date	06795612.8	08.08.2006
	[2009/17]
	WO2006IB52732
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2008017903
	Date:	14.02.2008
	Language:	EN
	[2008/07]
	Type:	A1 Application with search report
	No.:	EP2049482
	Date:	22.04.2009
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 14.02.2008 takes the place of the publication of the European patent application.
	[2009/17]
	Type:	B1 Patent specification
	No.:	EP2049482
	Date:	21.10.2015
	Language:	EN
	[2015/43]
Search report(s)	International search report - published on:	KR	14.02.2008
	(Supplementary) European search report - dispatched on:	EP	27.04.2010
Classification	IPC:	C07D209/12, C07D491/04, C07D231/12	[2009/17]
	CPC:	C07C219/10 (EP); A61K38/05 (EP); A61K38/13 (EP); C07D207/337 (EP); C07D209/28 (EP); C07D231/12 (EP); (+) C07D231/56 (EP); C07D277/30 (EP); C07D491/04 (EP) (-)
	C-Set:	A61K38/05, A61K2300/00 (EP)
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2015/43]
Former [2009/17]	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR
Extension states	AL	Not yet paid
	BA	Not yet paid
	HR	Not yet paid
	MK	Not yet paid
	RS	Not yet paid
Title	German:	POSITIV GELADENE, WASSERLÖSLICHE PRODRUGS VON ARYL- UND HETEROARYLESSIGSÄUREN MIT SEHR SCHNELLER HAUTPENETRATIONSGESCHWINDIGKEIT	[2009/17]
	English:	POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF ARYL- AND HETEROARYLACETIC ACIDS WITH VERY FAST SKIN PENETRATION RATE	[2009/17]
	French:	PROMÉDICAMENTS HYDROSOLUBLES CHARGÉS POSITIVEMENT D'ACIDES ARYL- ET HETEROARYLACETIQUES AVEC UNE VITESSE DE PÉNÉTRATION DE LA PEAU TRÈS RAPIDE	[2009/17]
Entry into regional phase	11.02.2009	National basic fee paid
	11.02.2009	Search fee paid
	11.02.2009	Designation fee(s) paid
	11.02.2009	Examination fee paid
Examination procedure	11.02.2009	Examination requested [2009/17]
	18.11.2010	Amendment by applicant (claims and/or description)
	13.11.2012	Despatch of a communication from the examining division (Time limit: M04)
	25.03.2013	Reply to a communication from the examining division
	12.04.2013	Despatch of a communication from the examining division (Time limit: M04)
	09.08.2013	Reply to a communication from the examining division
	27.08.2013	Despatch of a communication from the examining division (Time limit: M04)
	06.01.2014	Reply to a communication from the examining division
	04.03.2014	Despatch of a communication from the examining division (Time limit: M06)
	10.09.2014	Reply to a communication from the examining division
	19.02.2015	Despatch of a communication from the examining division (Time limit: M01)
	30.03.2015	Reply to a communication from the examining division
	12.05.2015	Communication of intention to grant the patent
	11.09.2015	Fee for grant paid
	11.09.2015	Fee for publishing/printing paid
	11.09.2015	Receipt of the translation of the claim(s)
Divisional application(s)	EP15190570.0 / EP2990402
	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 13.11.2012
Opposition(s)	22.07.2016	No opposition filed within time limit [2016/39]
Fees paid	Renewal fee
	11.02.2009	Renewal fee patent year 03
	11.02.2009	Renewal fee patent year 04
	17.08.2010	Renewal fee patent year 05
	11.08.2011	Renewal fee patent year 06
	10.08.2012	Renewal fee patent year 07
	19.08.2013	Renewal fee patent year 08
	13.08.2014	Renewal fee patent year 09
	10.08.2015	Renewal fee patent year 10
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	BG	21.10.2015
	CY	21.10.2015
	EE	21.10.2015
	LT	21.10.2015
	LV	21.10.2015
	MC	21.10.2015
	SI	21.10.2015
	SK	21.10.2015
	IS	21.02.2016
	[2018/38]
Former [2018/29]	CY	21.10.2015
	EE	21.10.2015
	LT	21.10.2015
	LV	21.10.2015
	MC	21.10.2015
	SI	21.10.2015
	SK	21.10.2015
	IS	21.02.2016
Former [2017/23]	EE	21.10.2015
	LT	21.10.2015
	LV	21.10.2015
	MC	21.10.2015
	SI	21.10.2015
	SK	21.10.2015
	IS	21.02.2016
Former [2016/49]	EE	21.10.2015
	LT	21.10.2015
	LV	21.10.2015
	SI	21.10.2015
	SK	21.10.2015
	IS	21.02.2016
Former [2016/36]	EE	21.10.2015
	LT	21.10.2015
	LV	21.10.2015
	SK	21.10.2015
	IS	21.02.2016
Former [2016/25]	LT	21.10.2015
	LV	21.10.2015
	IS	21.02.2016
Former [2016/22]	LT	21.10.2015
	IS	21.02.2016
Former [2016/20]	LT	21.10.2015
Documents cited:	Search	[X] - VENUTI M C ET AL, "SYNTHESIS AND BIOLOGICAL EVALUATION OF OMEGA-(N,N,N-TRIALKYLAMMONIUM) ALKYL ESTERS AND THIOESTERS OF CARBOXYLIC ACID NONSTEROIDAL ANTIINFLAMMATORY AGENTS", PHARMACEUTICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS, NEW YORK, NY, US LNKD- DOI:10.1023/A:1015960522189, (19890101), vol. 6, no. 10, ISSN 0724-8741, pages 867 - 873, XP001098334 [X] 1-11 * page 869; table I * * page 871 - page 872; table II * DOI: http://dx.doi.org/10.1023/A:1015960522189
	International search	[X]WO03029187 (DOMPE SPA [IT], et al);
		[A]WO0158852 (DOMPE SPA [IT], et al);
		[A]WO02068377 (DOMPE SPA [IT], et al);
		[A]FR2410641 (MENARINI SAS [IT]);
		[A]FR1593024
		[X] - SONG N. ET AL, "Synthesis of a derivative quaternary ammonium-ibuprofen", JOURNAL OF OCEAN UNIVERSITY OF QINGDAO, (2002), vol. 32, no. 6, pages 911 - 913, XP001539131
	by applicant	US5192753
		US7052715
		US6416772
		US6346278
		US6444234
		US5654337
		US6190690
		US6528040
		US5885597
		- SUSAN MILOSOVICH ET AL., J. PHARM. SCI., (1993), vol. 82, page 227
		- D'AMOUR-SMITH, J. PHARMACAL. EXP. THER., (1941), vol. 72, page 74

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