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Extract from the Register of European Patents

EP About this file: EP1963370

EP1963370 - BISPECIFIC LIGANDS WITH BINDING SPECIFICITY TO CELL SURFACE TARGETS AND METHODS OF USE THEREFOR [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 15.02.2013 Database last updated on 05.10.2024
Most recent event Tooltip	15.02.2013	Application deemed to be withdrawn	published on 20.03.2013 [2013/12]
Applicant(s)	For all designated states Domantis Limited 315 Cambridge Science Park Cambridge Cambridgeshire, CB4 OWG / GB
	[2008/36]
Inventor(s)	01 / DE ANGELIS, Elena 315 Cambridge Science Park Cambridge CB4 0WG / GB
	02 / HOLMES, Steve 315 Cambridge Science Park Cambridge CB4 0WG / GB
	03 / TOMLISON, Ian, M. 315 Cambridge Science Park Cambridge CB4 0WG / GB
	04 / HUANG, Eric, Yi-Chun 315 Cambridge Science Park Cambridge CB4 0WG / GB
	05 / HOLT, Lucy, J. 315 Cambridge Science Park Cambridge CB4 0WG / GB
	06 / EVERETT, Claire, E. 315 Cambridge Science Park Cambridge CB4 0WG / GB
	[2008/36]
Representative(s)	Clube, Jasper Rupert, et al GlaxoSmithKline Global Patents (CN925.1) 980 Great West Road Brentford, Middlesex TW8 9GS / GB
	[N/P]
Former [2008/36]	Clube, Jasper Rupert, et al GlaxoSmith Kline CIP - CN 925.1 980 Great West Road Brentford, Middlesex TW8 9GS / GB
Application number, filing date	06808727.9	05.12.2006
	[2008/36]
	WO2006GB04565
Priority number, date	US20050742992P	06.12.2005 Original published format: US 742992 P
	[2008/36]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2007066109
	Date:	14.06.2007
	Language:	EN
	[2007/24]
	Type:	A1 Application with search report
	No.:	EP1963370
	Date:	03.09.2008
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 14.06.2007 takes the place of the publication of the European patent application.
	[2008/36]
Search report(s)	International search report - published on:	EP	14.06.2007
Classification	IPC:	C07K16/28, C07K16/30, A61K38/02	[2008/36]
	CPC:	C07K16/2803 (EP,US); C07K16/28 (KR); A61K47/6817 (EP,US); A61K47/6843 (EP,US); A61K47/6849 (EP,US); A61K47/6853 (EP,US); (+) A61P1/04 (EP); A61P11/06 (EP); A61P15/00 (EP); A61P17/00 (EP); A61P17/06 (EP); A61P19/02 (EP); A61P21/04 (EP); A61P25/00 (EP); A61P29/00 (EP); A61P3/10 (EP); A61P31/04 (EP); A61P31/12 (EP); A61P35/00 (EP); A61P35/02 (EP); A61P35/04 (EP); A61P37/02 (EP); A61P37/04 (EP); A61P37/08 (EP); C07K16/00 (KR); C07K16/2896 (EP,US); C07K16/30 (KR); C07K16/3007 (EP,US); A61K2039/505 (EP,US); C07K2317/31 (EP,US); C07K2317/569 (EP,US); C07K2317/77 (EP,US) (-)
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2008/36]
Extension states	HR	20.06.2008
Title	German:	BISPEZIFISCHE LIGANDEN MIT BINDUNGSSPEZIFITÄT FÜR ZIELE AN DER ZELLOBERFLÄCHE UND VERFAHREN ZU DEREN ANWENDUNG	[2008/36]
	English:	BISPECIFIC LIGANDS WITH BINDING SPECIFICITY TO CELL SURFACE TARGETS AND METHODS OF USE THEREFOR	[2008/36]
	French:	LIGANDS BISPECIFIQUES AYANT UNE SPECIFICITE DE LIAISON A DES CIBLES DE SURFACE CELLULAIRE ET PROCEDES D'UTILISATION DE CEUX-CI	[2008/36]
Entry into regional phase	20.06.2008	National basic fee paid
	20.06.2008	Designation fee(s) paid
	20.06.2008	Examination fee paid
Examination procedure	20.06.2008	Examination requested [2008/36]
	05.08.2008	Amendment by applicant (claims and/or description)
	07.05.2010	Despatch of a communication from the examining division (Time limit: M06)
	04.11.2010	Reply to a communication from the examining division
	09.05.2012	Despatch of a communication from the examining division (Time limit: M04)
	20.09.2012	Application deemed to be withdrawn, date of legal effect [2013/12]
	29.10.2012	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2013/12]
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 07.05.2010
Fees paid	Renewal fee
	08.12.2008	Renewal fee patent year 03
	07.12.2009	Renewal fee patent year 04
	22.11.2010	Renewal fee patent year 05
	07.12.2011	Renewal fee patent year 06
	Penalty fee
	Additional fee for renewal fee
	31.12.2012	07 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited in	International search	[PX]WO2006099875 (GENMAB AS [DK], et al) [PX] 1-7,44-53 * paragraph [0098] *;
		[A]WO2004032961 (MERCK PATENT GMBH [DE], et al) [A] 1-108 * page 12, line 16 - line 17 *;
		[A]WO2005044858 (ABLYNX NV [BE], et al) [A] 1-108 * the whole document *;
		[A]WO2004058820 (DOMANTIS LTD [GB], et al) [A] 25 * sequence 10 *
		[X] - VALLERA DANIEL A ET AL, "A bispecific recombinant immunotoxin, DT2219, targeting human CD19 and CD22 receptors in a mouse xenograft model of B-cell leukemia/lymphoma.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 15 MAY 2005, (20050515), vol. 11, no. 10, ISSN 1078-0432, pages 3879 - 3888, XP002425289 [X] 1-108 * page 3885 - page 3886 * DOI: http://dx.doi.org/10.1158/1078-0432.CCR-04-2290
		[X] - SCHMIDT M ET AL, "A BIVALENT SINGLE-CHAIN ANTIBODY-TOXIN SPECIFIC FOR ERB-2 AND THE EGF RECEPTOR", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, (19960208), vol. 65, no. 4, ISSN 0020-7136, pages 538 - 546, XP000646380 [X] 11-108 * page 538 * * page 549 * DOI: http://dx.doi.org/10.1002/(SICI)1097-0215(19960208)65:4<538::AID-IJC24>3.0.CO;2-4
		[PX] - IAN TOMLINSON, "Domantis Dual Targeting Domain antibodies shown to kill multiple myeloma cells and spare healthy cells", IBD ANTIBODY ENGINEERING 2005, (20051207), URL: http://www.domantis.com/IBC%20Tomlinson%2007_12_05%20for.pdf, (20070319), XP002425290 [PX] 1-108 * IBC's 16th International Conference on Antibody Engineering, San Diego, 5-8 December 2005 *
		[L] - DOMANTIS, "DOMANTIS? DUAL TARGETING DOMAIN ANTIBODIES SHOWN TO KILL MULTIPLE MYELOMA CELLS AND SPARE HEALTHY CELLS", PRESS RELEASE, (20051207), URL: http://www.domantis.com/, (20070319), XP002428485 [L] * the whole document *
	Examination	- Funaro ET AL, "CD38 functions are regulated through an internalization step.", The Journal of Immunology, (19980301), vol. 160, no. 5, ISSN 0022-1767, pages 2238 - 2247, XP055025944
		- LIU CHUNSHENG ET AL, "Targeted Gene Delivery into Human Myeloma Cells by an Engineered Anti-CD38 Single Chain Variable Fragment (scFv)-Protamine Complex.", BLOOD, & 44TH ANNUAL MEETING OF THE AMERICAN SOCIETY OF HEMATOLOGY; PHILADELPHIA, PA, USA; DECEMBER 06-10, 2002, (20021116), vol. 100, no. 11, ISSN 0006-4971, page Abstract No. 791

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