EP1931709 - FC VARIANTS WITH OPTIMIZED FC RECEPTOR BINDING PROPERTIES [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 13.10.2017 Database last updated on 24.08.2024 | |
Former | The patent has been granted Status updated on 04.11.2016 | Most recent event Tooltip | 06.03.2020 | Lapse of the patent in a contracting state New state(s): TR | published on 08.04.2020 [2020/15] | Applicant(s) | For all designated states Xencor, Inc. 111 W. Lemon Avenue Monrovia, CA 91016 / US | [2016/49] |
Former [2008/25] | For all designated states Xencor, Inc. 111 W. Lemon Avenue Monrovia, CA 91016 / US | Inventor(s) | 01 /
DESJARLAIS, John, R. 1030 North Michigan Avenue Pasadena, California 91104 / US | 02 /
KARKI, Sher, Bahadur 2833 Providence Way Pomona, CA 91767 / US | 03 /
LAZAR, Gregory, Alan 750 Arcadia Avenue, No. 6 Arcadia, California 91007 / US | 04 /
RICHARDS, John, Owen 893 San Marcus Lane Duarte, CA 91010 / US | 05 /
MOORE, Gregory, L. 152 Acacia Avenue Monrovia, California 91016 / US | 06 /
CARMICHAEL, David, Forrester 423 N, Primrose Avenue Monrovia, CA 91016 / US | [2008/33] |
Former [2008/25] | 01 /
DESJARLAIS, John, R. 1030 North Michigan Avenue Pasadena, California 91104 / US | ||
02 /
KARKI, Sher, Bahadur 300 North El Molino Avenue Pasadena, California 91101 / US | |||
03 /
LAZAR, Gregory, Alan 750 Arcadia Avenue, No. 6 Arcadia, California 91007 / US | |||
04 /
RICHARDS, John, Owen 893 San Marcus Lane Duarte, CA 91010 / US | |||
05 /
MOORE, Gregory, L. 152 Acacia Avenue Monrovia, California 91016 / US | |||
06 /
CARMICHAEL, David, Forrester 423 N, Primrose Avenue Monrovia, CA 91016 / US | Representative(s) | HGF HGF Limited Mill House North Street York YO1 6JD / GB | [N/P] |
Former [2016/49] | Taylor, Kate Laura HGF Limited Saviour House 9 St Saviourgate York YO1 8NQ / GB | ||
Former [2008/25] | Kiddle, Simon John, et al Mewburn Ellis LLP York House, 23 Kingsway London WC2B 6HP / GB | Application number, filing date | 06816248.6 | 03.10.2006 | [2008/25] | WO2006US38842 | Priority number, date | US20050723294P | 03.10.2005 Original published format: US 723294 P | US20050723335P | 03.10.2005 Original published format: US 723335 P | US20050739696P | 23.11.2005 Original published format: US 739696 P | US20050741966P | 02.12.2005 Original published format: US 741966 P | US20050750699P | 15.12.2005 Original published format: US 750699 P | US20060774358P | 17.02.2006 Original published format: US 774358 P | US20060779961P | 06.03.2006 Original published format: US 779961 P | US20060396495 | 31.03.2006 Original published format: US 396495 | US20060745078P | 18.04.2006 Original published format: US 745078 P | [2008/25] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2007041635 | Date: | 12.04.2007 | Language: | EN | [2007/15] | Type: | A2 Application without search report | No.: | EP1931709 | Date: | 18.06.2008 | Language: | EN | The application published by WIPO in one of the EPO official languages on 12.04.2007 takes the place of the publication of the European patent application. | [2008/25] | Type: | B1 Patent specification | No.: | EP1931709 | Date: | 07.12.2016 | Language: | EN | [2016/49] | Search report(s) | International search report - published on: | EP | 13.11.2008 | Classification | IPC: | C07K16/00 | [2008/25] | CPC: |
C07K16/00 (EP,US);
C07K16/2863 (EP,US);
C07K16/2887 (EP,US);
C07K16/30 (EP,US);
C07K2317/41 (EP,US);
C07K2317/52 (EP,US);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2016/49] |
Former [2008/25] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR | Extension states | AL | Not yet paid | BA | Not yet paid | HR | Not yet paid | MK | Not yet paid | RS | Not yet paid | Title | German: | FC-VARIANTEN MIT OPTIMIERTEN REZEPTORBINDUNGSEIGENSCHAFTEN | [2008/25] | English: | FC VARIANTS WITH OPTIMIZED FC RECEPTOR BINDING PROPERTIES | [2008/25] | French: | VARIANTS DE FC DOTÉS DE PROPRIÉTÉS DE LIAISON AUX RÉCEPTEURS FC OPTIMISÉES | [2008/25] | Entry into regional phase | 27.03.2008 | National basic fee paid | 27.03.2008 | Designation fee(s) paid | 27.03.2008 | Examination fee paid | Examination procedure | 27.03.2008 | Examination requested [2008/25] | 04.03.2011 | Despatch of a communication from the examining division (Time limit: M06) | 21.10.2011 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 29.12.2011 | Reply to a communication from the examining division | 29.01.2014 | Despatch of a communication from the examining division (Time limit: M06) | 08.08.2014 | Reply to a communication from the examining division | 12.02.2016 | Cancellation of oral proceeding that was planned for 18.02.2016 | 18.02.2016 | Date of oral proceedings (cancelled) | 18.04.2016 | Communication of intention to grant the patent | 24.08.2016 | Fee for grant paid | 24.08.2016 | Fee for publishing/printing paid | 24.08.2016 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 04.03.2011 | Opposition(s) | 08.09.2017 | No opposition filed within time limit [2017/46] | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 29.12.2011 | Request for further processing filed | 29.12.2011 | Full payment received (date of receipt of payment) Request granted | 17.01.2012 | Decision despatched | Fees paid | Renewal fee | 23.10.2008 | Renewal fee patent year 03 | 07.10.2009 | Renewal fee patent year 04 | 23.09.2010 | Renewal fee patent year 05 | 28.09.2011 | Renewal fee patent year 06 | 25.10.2012 | Renewal fee patent year 07 | 28.10.2013 | Renewal fee patent year 08 | 27.10.2014 | Renewal fee patent year 09 | 27.10.2015 | Renewal fee patent year 10 | 27.10.2016 | Renewal fee patent year 11 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 03.10.2006 | AT | 07.12.2016 | BE | 07.12.2016 | CY | 07.12.2016 | CZ | 07.12.2016 | EE | 07.12.2016 | ES | 07.12.2016 | FI | 07.12.2016 | IT | 07.12.2016 | LT | 07.12.2016 | LV | 07.12.2016 | MC | 07.12.2016 | PL | 07.12.2016 | RO | 07.12.2016 | SI | 07.12.2016 | SK | 07.12.2016 | TR | 07.12.2016 | BG | 07.03.2017 | GR | 08.03.2017 | IS | 07.04.2017 | PT | 07.04.2017 | [2020/15] |
Former [2019/46] | HU | 03.10.2006 | |
AT | 07.12.2016 | ||
BE | 07.12.2016 | ||
CY | 07.12.2016 | ||
CZ | 07.12.2016 | ||
EE | 07.12.2016 | ||
ES | 07.12.2016 | ||
FI | 07.12.2016 | ||
IT | 07.12.2016 | ||
LT | 07.12.2016 | ||
LV | 07.12.2016 | ||
MC | 07.12.2016 | ||
PL | 07.12.2016 | ||
RO | 07.12.2016 | ||
SI | 07.12.2016 | ||
SK | 07.12.2016 | ||
BG | 07.03.2017 | ||
GR | 08.03.2017 | ||
IS | 07.04.2017 | ||
PT | 07.04.2017 | ||
Former [2019/31] | HU | 03.10.2006 | |
AT | 07.12.2016 | ||
BE | 07.12.2016 | ||
CZ | 07.12.2016 | ||
EE | 07.12.2016 | ||
ES | 07.12.2016 | ||
FI | 07.12.2016 | ||
IT | 07.12.2016 | ||
LT | 07.12.2016 | ||
LV | 07.12.2016 | ||
MC | 07.12.2016 | ||
PL | 07.12.2016 | ||
RO | 07.12.2016 | ||
SI | 07.12.2016 | ||
SK | 07.12.2016 | ||
BG | 07.03.2017 | ||
GR | 08.03.2017 | ||
IS | 07.04.2017 | ||
PT | 07.04.2017 | ||
Former [2018/29] | AT | 07.12.2016 | |
BE | 07.12.2016 | ||
CZ | 07.12.2016 | ||
EE | 07.12.2016 | ||
ES | 07.12.2016 | ||
FI | 07.12.2016 | ||
IT | 07.12.2016 | ||
LT | 07.12.2016 | ||
LV | 07.12.2016 | ||
MC | 07.12.2016 | ||
PL | 07.12.2016 | ||
RO | 07.12.2016 | ||
SI | 07.12.2016 | ||
SK | 07.12.2016 | ||
BG | 07.03.2017 | ||
GR | 08.03.2017 | ||
IS | 07.04.2017 | ||
PT | 07.04.2017 | ||
Former [2017/52] | AT | 07.12.2016 | |
BE | 07.12.2016 | ||
CZ | 07.12.2016 | ||
EE | 07.12.2016 | ||
ES | 07.12.2016 | ||
FI | 07.12.2016 | ||
IT | 07.12.2016 | ||
LT | 07.12.2016 | ||
LV | 07.12.2016 | ||
PL | 07.12.2016 | ||
RO | 07.12.2016 | ||
SI | 07.12.2016 | ||
SK | 07.12.2016 | ||
BG | 07.03.2017 | ||
GR | 08.03.2017 | ||
IS | 07.04.2017 | ||
PT | 07.04.2017 | ||
Former [2017/38] | AT | 07.12.2016 | |
BE | 07.12.2016 | ||
CZ | 07.12.2016 | ||
EE | 07.12.2016 | ||
ES | 07.12.2016 | ||
FI | 07.12.2016 | ||
IT | 07.12.2016 | ||
LT | 07.12.2016 | ||
LV | 07.12.2016 | ||
PL | 07.12.2016 | ||
RO | 07.12.2016 | ||
SK | 07.12.2016 | ||
BG | 07.03.2017 | ||
GR | 08.03.2017 | ||
IS | 07.04.2017 | ||
PT | 07.04.2017 | ||
Former [2017/35] | CZ | 07.12.2016 | |
EE | 07.12.2016 | ||
ES | 07.12.2016 | ||
FI | 07.12.2016 | ||
LT | 07.12.2016 | ||
LV | 07.12.2016 | ||
RO | 07.12.2016 | ||
GR | 08.03.2017 | ||
Former [2017/28] | ES | 07.12.2016 | |
FI | 07.12.2016 | ||
LT | 07.12.2016 | ||
LV | 07.12.2016 | ||
GR | 08.03.2017 | ||
Former [2017/12] | LV | 07.12.2016 | Cited in | International search | [X]WO2004099249 (XENCOR INC [US], et al) [X] 1-11,18-21 * pages 137-138 * * page 142; table 65 * * example 13 *; | [X]WO2004029207 (XENCOR INC [US], et al) [X] 1-7,9-11,18-21 * page 136 * * example 7; table 63 *; | [Y]WO0042072 (GENENTECH INC [US]) [Y] 1-11,18-21 * table 6 *; | [E]WO2007044616 (XENCOR INC [US], et al) [E] 1-11,18-21 * page 3, paragraph 11; figure 16 * * page 72, paragraph 271 *; | [EL]WO2007008943 (XENCOR INC [US], et al) [EL] 1-11,18-21 * page 37, paragraph 144 * * examples 4,7 *; | [EL]WO2006105338 (XENCOR INC [US], et al) [EL] 1-11,18-21 * paragraphs [0046] - [0048] * | [Y] - SHIELDS R L ET AL, "High resolution mapping of the binding site on human IgG1 for FcgammaRI, FcgammaRII, FcgammaRIII, and FcRn and design of IgG1 variants with improved binding to the FcgammaR", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, (20010302), vol. 276, no. 9, ISSN 0021-9258, pages 6591 - 6604, XP002271092 [Y] 1-11,18-21 * pages 6591-2, paragraph BRIDGING; table I * DOI: http://dx.doi.org/10.1074/jbc.M009483200 | [XP] - LAZAR G A ET AL, "Engineered antibody Fc variants with enhanced effector function", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, (200603), vol. 103, no. 11, ISSN 0027-8424, pages 4005 - 4010, XP002403708 [XP] 1-11,18-21 * table 1 * DOI: http://dx.doi.org/10.1073/pnas.0508123103 |