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Extract from the Register of European Patents

EP About this file: EP1954720

EP1954720 - ANTIBODIES AND IMMUNOTOXINS THAT TARGET HUMAN GLYCOPROTEIN NMB [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  20.03.2009
Database last updated on 02.11.2024
Most recent event   Tooltip20.03.2009Withdrawal of applicationpublished on 22.04.2009  [2009/17]
Applicant(s)For all designated states
The Government of the United States of America, as represented by the Secretary of Health and Human Services
National Institutes of Health, Office of Technology Transfer, 6011 Executive Boulevard, Suite 325
Rockville, MD 20852-3804 / US
For all designated states
Duke University
University Office of Science and Technology, Davidson Building, Room 454, DUMC 3664
Durham, NC 27710 / US
[N/P]
Former [2008/33]For all designated states
The Government of the United States of America, as Represented by the Secretary of Health and Human Services, National Institu
6011 Executive Boulevard
Rockville MD 20852 / US
For all designated states
Duke University
University Office of Science and Technology, Davidson Building, Room 454, DUMC 3664
Durham, NC 27710 / US
Inventor(s)01 / KUAN, Chien-Tsun
202 Hardenbrook Court
Cary, North Carolina 27519 / US
02 / BIGNER, Darell, D.
5133 Corbett Ridge Road
Mebane, North Carolina 27302 / US
03 / PASTAN, Ira, H.
11710 Beall Mountain Road
Potomac, Maryland 20854 / US
 [2008/33]
Representative(s)Tombling, Adrian George, et al
Withers & Rogers LLP
2 London Bridge
London SE1 9RA / GB
[N/P]
Former [2008/33]Tombling, Adrian George, et al
Withers & Rogers LLP Goldings House 2 Hays Lane
London SE1 2HW / GB
Application number, filing date06827329.131.10.2006
[2008/33]
WO2006US42735
Priority number, dateUS20050732227P31.10.2005         Original published format: US 732227 P
[2008/33]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007053718
Date:10.05.2007
Language:EN
[2007/19]
Type: A1 Application with search report 
No.:EP1954720
Date:13.08.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 10.05.2007 takes the place of the publication of the European patent application.
[2008/33]
Search report(s)International search report - published on:EP10.05.2007
ClassificationIPC:C07K16/30, A61K39/395, A61P35/00, C12N15/13, A61K47/48, G01N33/68, A61K51/10
[2008/33]
CPC:
C07K16/30 (EP,US); C07K16/28 (US); A61K47/6817 (EP,US);
A61P29/00 (EP); A61P31/04 (EP); A61P35/00 (EP);
A61P43/00 (EP); C07K16/1214 (US); C12N15/00 (EP,US);
G01N33/57484 (EP,US); A61K2039/505 (EP,US); C07K2317/565 (US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/33]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:ANTIKÖRPER UND IMMUNOTOXINE, DIE AUF DAS HUMANE GLYCOPROTEIN NMB ZIELEN[2008/33]
English:ANTIBODIES AND IMMUNOTOXINS THAT TARGET HUMAN GLYCOPROTEIN NMB[2008/33]
French:ANTICORPS ET IMMUNOTOXINES CIBLANT LA GLYCOPROTEINE HUMAINE NMB[2008/33]
Entry into regional phase15.05.2008National basic fee paid 
15.05.2008Designation fee(s) paid 
15.05.2008Examination fee paid 
Examination procedure16.05.2008Amendment by applicant (claims and/or description)
16.05.2008Examination requested  [2008/33]
06.03.2009Application withdrawn by applicant  [2009/17]
Fees paidRenewal fee
15.05.2008Renewal fee patent year 03
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Cited inInternational search[PX]WO2006071441  (CURAGEN CORP [US], et al) [PX] 1-41 * the whole document *;
 [DX]  - KUAN C-T ET AL, "MONOCLONAL ANTIBODIES RECOGNIZING HUMAN GPNMBWT/GPNMBSV REACT WITH HUMAN HIGH-GRADE GLIOMAS (HGL)", PROCEEDINGS OF THE ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, NEW YORK, NY, US, (200307), vol. 44, ISSN 0197-016X, pages 1116 - 1117, XP008070220 [DX] 1-41 * abstract *
 [X]  - KUAN ET AL, "GPNMB: A new target for human high-grade gliomas (HGL) immunotherapy", NEURO-ONCOLOGY, vol. 7, no. 3, (200507), pages 369 - 369, URL: http://neuro-oncology.dukejournals.org/cgi/reprint/7/3/279, (20070216), XP002420602 [X] 1-41 * abstract *
 [X]  - KAM FAI TSE ET AL, "CR011, a potent fully human monoclonal antibody-auristatin E conjugated prodrug targeting melanoma", PROCEEDINGS OF THE ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, NEW YORK, NY, US, (20050416), ISSN 0197-016X, XP002403962 [X] 1-41 * abstract *
 [PX]  - TSE KAM FAI ET AL, "CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (20060215), vol. 12, no. 4, ISSN 1078-0432, pages 1373 - 1382, XP002403963 [PX] 1-41 * abstract *

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-05-2018
 [PX]  - KUAN CHIEN-TSUN ET AL, "Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 1 APR 2006, (20060401), vol. 12, no. 7 Pt 1, ISSN 1078-0432, pages 1970 - 1982, XP002420603 [PX] 36-41 * page 1979 *

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-05-2797
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