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Extract from the Register of European Patents

EP About this file: EP1977237

EP1977237 - PROGNOSIS PREDICTION FOR COLORECTAL CANCER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  17.07.2015
Database last updated on 06.11.2024
Most recent event   Tooltip08.07.2016Lapse of the patent in a contracting state
New state(s): HU, TR		published on 10.08.2016  [2016/32]
Applicant(s)For all designated states
Pacific Edge Biotechnology Limited
C/-Deloitte 8th Floor, Otago House 481 Moray Place
Dunedin / NZ
[2008/41]
Inventor(s)01 / NEKARDA, Hjalmar
Humboldtstrasse 248
45149 Essen / DE
02 / FRIEDERICHS, Jan
Dorfstrasse 47
82418 Murnau-Weindorf / DE
03 / HOLZMANN, Bernhard
Department of Surgery
Technische Universität
Ismaninger Strasse 22
81675 München / DE
04 / ROSENBERG, Robert
Höslstrasse 2
81927 Munich / DE
05 / REEVE, Anthony Edmund
22 Como Street
Maori Hill
Dunedin / NZ
06 / BLACK, Michael Alan
17 Falcon Street
Roslyn
Dunedin / NZ
07 / MCCALL, John Lindsay
148 Konini Road
Titirangi
Auckland / NZ
08 / LIN, Yu-Hsin
66 Poulters Road
Leith Valley
Dunedin / NZ
09 / POLLOCK, Robert Craig
4 Springhill Terrace
Mornington
Dunedin / NZ
 [2014/37]
Former [2009/13]01 / NEKARDA, Hjalmar
Humboldtstrasse 248
45149 Essen / DE
02 / FRIEDERICHS, Jan
Dorfstrasse 47
82418 Murnau-Weindorf / DE
03 / HOLZMANN, Bernhard
Department of Surgery, Technische Universität, Ismaninger Strasse 22
81675 München / DE
04 / ROSENBERG, Robert
Höslstrasse 2
81927 Munich / DE
05 / REEVE, Anthony Edmund
22 Como Street Maori Hill
Dunedin / NZ
06 / BLACK, Michael Alan
17 Falcon Street Roslyn
Dunedin / NZ
07 / MCCALL, John Lindsay
148 Konini Road Titirangi
Auckland / NZ
08 / LIN, Yu-Hsin
66 Poulters Road Leith Valley
Dunedin / NZ
09 / POLLOCK, Robert Craig
4 Springhill Terrace Mornington
Dunedin / NZ
Former [2008/41]01 / NEKARDA, Hjalmar
Edelweisstrasse 2a
82024 Taufkirchen / DE
02 / FRIEDERICHS, Jan
Department of Surgery, Technische Universität, Ismaninger Strasse 22
81675 München / DE
03 / HOLZMANN, Bernhard
Department of Surgery, Technische Universität, Ismaninger Strasse 22
81675 München / DE
04 / ROSENBERG, Robert
Scheinerstrasse 7
81679 Munich / DE
05 / REEVE, Anthony Edmund
22 Como Street Maori Hill
Dunedin / NZ
06 / BLACK, Michael Alan
17 Falcon Street Roslyn
Dunedin / NZ
07 / MCCALL, John Lindsay
148 Konini Road Titirangi
Auckland / NZ
08 / LIN, Yu-Hsin
66 Poulters Road Leith Valley
Dunedin / NZ
09 / POLLOCK, Robert Craig
4 Springhill Terrace Mornington
Dunedin / NZ
Representative(s)Wright, Simon Mark, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[2014/37]
Former [2010/30]Wright, Simon Mark, et al
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Former [2008/41]Bittner, Thomas L.
Forrester & Boehmert Pettenkoferstrasse 20-22
80336 München / DE
Application number, filing date06835771.422.12.2006
[2008/41]
WO2006NZ00343
Priority number, dateNZ2005054443223.12.2005         Original published format: NZ 54443205
[2008/41]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007073220
Date:28.06.2007
Language:EN
[2007/26]
Type: A1 Application with search report 
No.:EP1977237
Date:08.10.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 28.06.2007 takes the place of the publication of the European patent application.
[2008/41]
Type: B1 Patent specification 
No.:EP1977237
Date:10.09.2014
Language:EN
[2014/37]
Search report(s)International search report - published on:AU28.06.2007
(Supplementary) European search report - dispatched on:EP11.02.2009
ClassificationIPC:C12Q1/68, G01N33/50, G01N33/53, G06F19/00, G01N33/68
[2009/11]
CPC:
C12Q1/6886 (EP,KR,US); G01N33/57419 (EP,KR,US); G16B20/00 (EP,US);
G16B20/20 (EP,KR,US); G16B25/10 (EP,KR,US); G16B25/20 (KR);
G16B25/30 (KR); C12Q2600/118 (EP,KR,US); C12Q2600/158 (EP,KR,US);
C12Q2600/16 (KR,US); G16B25/00 (EP,US) (-)
Former IPC [2008/41]G01N33/50, G01N33/53, G06F19/00, C12Q1/68, G01N33/68
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/41]
TitleGerman:VORHERSAGE DER PROGNOSE FÜR KOLOREKTALKARZINOM[2008/41]
English:PROGNOSIS PREDICTION FOR COLORECTAL CANCER[2008/41]
French:PREDICTION D'EVOLUTION D'UN CANCER COLORECTAL[2008/41]
Entry into regional phase18.07.2008National basic fee paid 
18.07.2008Search fee paid 
18.07.2008Designation fee(s) paid 
18.07.2008Examination fee paid 
Examination procedure18.07.2008Examination requested  [2008/41]
01.10.2008Amendment by applicant (claims and/or description)
24.06.2009Despatch of a communication from the examining division (Time limit: M06)
04.01.2010Reply to a communication from the examining division
28.01.2011Despatch of a communication from the examining division (Time limit: M06)
08.08.2011Reply to a communication from the examining division
11.06.2012Cancellation of oral proceeding that was planned for 14.06.2012
14.06.2012Date of oral proceedings (cancelled)
31.01.2013Despatch of a communication from the examining division (Time limit: M04)
05.06.2013Reply to a communication from the examining division
18.10.2013Communication of intention to grant the patent
28.02.2014Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
26.03.2014Communication of intention to grant the patent
31.07.2014Fee for grant paid
31.07.2014Fee for publishing/printing paid
31.07.2014Receipt of the translation of the claim(s)
Divisional application(s)EP11172410.0  / EP2371972
EP11172587.5  / EP2392678
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  24.06.2009
Opposition(s)11.06.2015No opposition filed within time limit [2015/34]
Fees paidRenewal fee
22.12.2008Renewal fee patent year 03
11.12.2009Renewal fee patent year 04
16.06.2011Renewal fee patent year 05
15.02.2012Renewal fee patent year 06
11.12.2012Renewal fee patent year 07
20.12.2013Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.12.201005   M06   Fee paid on   16.06.2011
31.12.201106   M06   Fee paid on   15.02.2012
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU22.12.2006
BG10.09.2014
CY10.09.2014
CZ10.09.2014
DK10.09.2014
EE10.09.2014
FI10.09.2014
LT10.09.2014
LV10.09.2014
MC10.09.2014
PL10.09.2014
RO10.09.2014
SI10.09.2014
SK10.09.2014
TR10.09.2014
GR11.12.2014
LU22.12.2014
IS10.01.2015
PT12.01.2015
[2016/32]
Former [2016/27]BG10.09.2014
CY10.09.2014
CZ10.09.2014
DK10.09.2014
EE10.09.2014
FI10.09.2014
LT10.09.2014
LV10.09.2014
MC10.09.2014
PL10.09.2014
RO10.09.2014
SI10.09.2014
SK10.09.2014
GR11.12.2014
LU22.12.2014
IS10.01.2015
PT12.01.2015
Former [2016/25]BG10.09.2014
CY10.09.2014
CZ10.09.2014
DK10.09.2014
EE10.09.2014
FI10.09.2014
LT10.09.2014
LV10.09.2014
PL10.09.2014
RO10.09.2014
SI10.09.2014
SK10.09.2014
GR11.12.2014
LU22.12.2014
IS10.01.2015
PT12.01.2015
Former [2015/50]CY10.09.2014
CZ10.09.2014
DK10.09.2014
EE10.09.2014
FI10.09.2014
LT10.09.2014
LV10.09.2014
PL10.09.2014
RO10.09.2014
SI10.09.2014
SK10.09.2014
GR11.12.2014
LU22.12.2014
IS10.01.2015
PT12.01.2015
Former [2015/35]CY10.09.2014
CZ10.09.2014
DK10.09.2014
EE10.09.2014
FI10.09.2014
LT10.09.2014
LV10.09.2014
PL10.09.2014
RO10.09.2014
SK10.09.2014
GR11.12.2014
LU22.12.2014
IS10.01.2015
PT12.01.2015
Former [2015/24]CY10.09.2014
CZ10.09.2014
EE10.09.2014
FI10.09.2014
LT10.09.2014
LV10.09.2014
PL10.09.2014
RO10.09.2014
SK10.09.2014
GR11.12.2014
IS10.01.2015
PT12.01.2015
Former [2015/23]CY10.09.2014
CZ10.09.2014
EE10.09.2014
FI10.09.2014
LT10.09.2014
LV10.09.2014
RO10.09.2014
SK10.09.2014
GR11.12.2014
IS10.01.2015
PT12.01.2015
Former [2015/22]CY10.09.2014
FI10.09.2014
LT10.09.2014
LV10.09.2014
RO10.09.2014
GR11.12.2014
PT12.01.2015
Former [2015/12]CY10.09.2014
FI10.09.2014
LT10.09.2014
LV10.09.2014
GR11.12.2014
Former [2015/11]CY10.09.2014
FI10.09.2014
LT10.09.2014
GR11.12.2014
Former [2015/09]FI10.09.2014
LT10.09.2014
Former [2015/08]LT10.09.2014
Documents cited:Search[X]WO02068677  (EOS BIOTECHNOLOGY INC [US], et al) [X] 1-18 * page 159; claim 1; table 17 *;
 [X]WO2004090550  (COLOTECH AS [DK], et al) [X] 1-18 * malate dehydrogenase = ME2; page 67 *;
 [X]WO2005064009  (AROS APPLIED BIOTECHNOLOGY APS [DK], et al) [X] 1-18 * page 92; claims 1-9 * * page 81; table 22 * * page 21; table 3 * * TNFRS6 = FAS; page 16; table 1 *;
 [X]  - GAO JIAN-JUN ET AL, "Evaluative significance of the expression of Fas antigen and P53 protein in colorectal cancer for the biological characters and prognosis", CHINESE JOURNAL OF CLINICAL REHABILITATION, CN, (20050101), vol. 9, ISSN 1671-5926, pages 228 - 229, XP008082293 [X] 1-18 * the whole document *
 [X]  - LIN MAN-HUA ET AL, "[Expression and clinical significance of nm23-H1, Fas and FasL in colorectal carcinoma tissues]", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (200507), Database accession no. NLM16078572, XP002512619 [X] 1-18 * abstract *
 [X]  - "Affymetrix GeneChip Human Genome U133 Array Set HG-U133A", GEO HOST- GEO, (20020311), XP002355386 [X] 4,5 * ME2 on page 230; page 230 * * TNFRS6 = FAS on page 363; page 363 *
    [ ] - SICHUAN DA XUE XUE BAO. YI XUE BAN = JOURNAL OF SICHUAN UNIVERSITY. MEDICAL SCIENCE EDITION JUL 2005, (200507), vol. 36, no. 4, ISSN 1672-173X, pages 503 - 505
International search[A]  - ESCHRICH S. ET AL., "Molecular staging for survival prediction of colorectal cancer patients", JOURNAL OF CLINICAL ONCOLOGY, (200505), vol. 23, no. 15, pages 3526 - 3535, XP003014768

DOI:   http://dx.doi.org/10.1200/JCO.2005.00.695
 [A]  - ARANGO D. ET AL., "Gene-expressing profiling predicts recurrence in Duke's C colorectal cancer", GASTROENTEROLOGY, (200509), vol. 129, pages 874 - 884, XP005314702

DOI:   http://dx.doi.org/10.1053/j.gastro.2005.06.066
 [A]  - WANG Y. ET AL., "Gene expression profiles and molecular markers to predict recurrence of Dukes' B colon cancer", JOURNAL OF CLINICAL ONCOLOGY, (2004), vol. 22, no. 9, pages 1564 - 1571, XP003014769

DOI:   http://dx.doi.org/10.1200/JCO.2004.08.186
 [A]  - BARRIER A. ET AL., "Colon cancer prognosis prediction by gene expression profiling", ONCOGENE, (200509), vol. 24, pages 6155 - 6164, XP002393868

DOI:   http://dx.doi.org/10.1038/sj.onc.1208984
 [A]  - BERTUCCI F. ET AL., "Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters", ONCOGENE, (2004), vol. 23, pages 1377 - 1391, XP002414422

DOI:   http://dx.doi.org/10.1038/sj.onc.1207262
 [A]  - GAO J.-J. ET AL., "Evaluative significance of the expression of Fas antigen and P53 protein in colorectal cancer for the biological characters and prognosis", CHINESE JOURNAL OF CLINICAL REHABILITATION, (200504), vol. 9, no. 14, pages 228 - 229, XP008082293
 [A]  - OGAWA S. ET AL., "The breakdown of apoptotic mechanism in the development and progression of colorectal carcinoma", ANTICANCER RESEARCH, (2004), vol. 24, pages 1569 - 1580, XP008082092
 [A]  - BACKUS H.H.J. ET AL., "Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases", JOURNAL OF CLINICAL PHARMACOLOGY, (2002), vol. 55, pages 206 - 211, XP003014770
Examination   - GREENBAUM D ET AL, "COMPARING PROTEIN ABUNDANCE AND MRNA EXPRESSION LEVELS ON A GENOMIC SCALE", GENOME BIOLOGY (ONLINE), BIOMED CENTRAL LTD, GB, (20030101), vol. 40, no. 9, ISSN 1465-6914, pages 117.01 - 117.08, XP008036618
    - OERNTOFT T F ET AL, "GENOME-WIDE STUDY OF GENE COPY NUMBERS, TRANSCRIPTS, AND PROTEIN LEVELS IN PAIRS OF NON-INVASIVE AND INVASIVE HUMAN TRANSITIONAL CELL CARCINOMAS", MOLECULAR & CELLULAR PROTEOMICS, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, INC, US, (20020101), vol. 1, no. 1, doi:10.1074/MCP.M100019-MCP200, ISSN 1535-9476, pages 37 - 45, XP008015037

DOI:   http://dx.doi.org/10.1074/mcp.M100019-MCP200
by applicantWO0206867
 WO2004090550
 WO2005064009
    - GAO ET AL., CHINESE JOUNRAL OF CLINICAL REHABILITATION, (20050109), pages 228 - 229
    - LIN ET AL., Journal of Sichuan University, MEDICAL SCIENCE EDITION, (200507), vol. 36, pages 503 - 505
    - GREENBAUM ET AL., GENOME BIOLOGY, (20030101), vol. 40, no. 9, pages 117.01 - 117.08
    - OERNTOFT ET AL., MOLECULAR AND CELLULAR PROTEOMICS, (20020101), vol. 1, no. 1, pages 37 - 45
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.