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Extract from the Register of European Patents

EP About this file: EP1957673

EP1957673 - MATERIALS AND METHODS FOR ABCB1 POLYMORPHIC VARIANT SCREENING, DIAGNOSIS, AND TREATMENT [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  26.10.2012
Database last updated on 22.01.2025
Most recent event   Tooltip26.10.2012Application deemed to be withdrawnpublished on 28.11.2012  [2012/48]
Applicant(s)For all designated states
Government of the United States of America, Represented by the Secretary, Department of Health and Human Services
Office of Technology Transfer 6011 Executive Boulevard, Suite 325
Rockville, Maryland 20852 / US
[2008/34]
Inventor(s)01 / FIGG, William D.
10451 Breckinridge LN
Fairfax, VA 22030 / US
02 / SPARREBOOM, Alexander
187 Ridgefield Road
Memphis, TN 38111 / US
03 / SISSUNG, Tristan M.
4708 Randolph Court
Annandale, VA 22003 / US
04 / PIEKARZ, Richard L.
1424 Crestridge Drive
Silver Spring, MD 20910 / US
05 / BATES, Susan E.
5404 Alta Vista Road
Bethesda, MD 20814 / US
 [2008/43]
Former [2008/34]01 / FIGG, William D.
10451 Breckinridge LN
Fairfax, VA 22030 / US
02 / SPARREBOOM, Alexander
187 Ridgefield Road
Memphis, TN 38111 / US
03 / SISSUNG, Tristan M.
4708 Randolph Court
Annandale, VA 22003 / US
04 / PIEKARZ, Richard L.
8708 First Ave.
Silver Spring, MD 20910 / US
05 / BATES, Susan E.
5404 Alta Vista Road
Bethesda, MD 20814 / US
Representative(s)Pfenning, Meinig & Partner mbB
Patent- und Rechtsanwälte
Theresienhöhe 11a
80339 München / DE
[N/P]
Former [2008/34]Pfenning, Meinig & Partner GbR
Patent- und Rechtsanwälte Theresienhöhe 13
80339 München / DE
Application number, filing date06837251.509.11.2006
[2008/34]
WO2006US43656
Priority number, dateUS20050736083P10.11.2005         Original published format: US 736083 P
[2008/34]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007058896
Date:24.05.2007
Language:EN
[2007/21]
Type: A2 Application without search report 
No.:EP1957673
Date:20.08.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 24.05.2007 takes the place of the publication of the European patent application.
[2008/34]
Search report(s)International search report - published on:EP04.10.2007
ClassificationIPC:C12Q1/68
[2008/34]
CPC:
C12Q1/6883 (EP,US); C12Q2600/106 (EP,US); C12Q2600/156 (EP,US);
C12Q2600/172 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/34]
TitleGerman:MATERIALIEN UND VERFAHREN ZUM SCREENING, ZUR DIAGNOSE UND BEHANDLUNG POLYMORPHER ABCB1-VARIANTEN[2008/34]
English:MATERIALS AND METHODS FOR ABCB1 POLYMORPHIC VARIANT SCREENING, DIAGNOSIS, AND TREATMENT[2008/34]
French:MATERIAUX ET PROCEDES POUR UN CRIBLAGE DE VARIANTS POLYMORPHES ABCB1, DIAGNOSTIC ET TRAITEMENT[2008/34]
Entry into regional phase04.06.2008National basic fee paid 
04.06.2008Designation fee(s) paid 
04.06.2008Examination fee paid 
Examination procedure04.06.2008Amendment by applicant (claims and/or description)
04.06.2008Examination requested  [2008/34]
05.11.2008Despatch of a communication from the examining division (Time limit: M04)
26.02.2009Reply to a communication from the examining division
01.06.2012Application deemed to be withdrawn, date of legal effect  [2012/48]
09.07.2012Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2012/48]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  05.11.2008
Fees paidRenewal fee
25.11.2008Renewal fee patent year 03
25.11.2009Renewal fee patent year 04
24.11.2010Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
30.11.201106   M06   Not yet paid
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[X]WO03013535  (EPIDAUROS BIOTECHNOLOGIE AG [DE], et al) [X] 56,59 * claims 1,3,9,18,20,24-26,37 *;
 [X]WO2004016759  (RAUCY JUDY [US]) [X] 56,59,60 * abstract * * example 6 *;
 [X]WO2004057030  (PFIZER PROD INC [US], et al) [X] 1-55,62 * claims 1-4 *;
 [X]  - XIAO JIM J ET AL, "Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-eth ylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicycl o[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines.", THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS JUL 2005, (200507), vol. 314, no. 1, ISSN 0022-3565, pages 467 - 475, XP002442474 [X] 56-58,60 * abstract * * section "Real-time RT-PCR" * * page 468, column 1, paragraph 1 *

DOI:   http://dx.doi.org/10.1124/jpet.105.083956
 [X]  - KROETZ D L ET AL, "Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene", PHARMACOGENETICS, CHAPMAN & HALL, LONDON, GB, (200308), vol. 13, no. 8, ISSN 0960-314X, pages 481 - 494, XP002982428 [X] 56-58 * page 483, column 1, paragraph L - column 2, paragraph 1 * * page 483, column 2, paragraph 3 *

DOI:   http://dx.doi.org/10.1097/00008571-200308000-00006
 [X]  - CLARK DAVID W J ET AL, "Linking pharmacovigilance with pharmacogenetics.", DRUG SAFETY : AN INTERNATIONAL JOURNAL OF MEDICAL TOXICOLOGY AND DRUG EXPERIENCE 2004, (2004), vol. 27, no. 15, ISSN 0114-5916, pages 1171 - 1184, XP009086760 [X] 60 * abstract * * page 1172, column 1, paragraph L * * page 1179, column 2, paragraph L *

DOI:   http://dx.doi.org/10.2165/00002018-200427150-00002
 [X]  - SANDOR V ET AL, "PHASE I TRIAL OF THE HISTONE DEACETYLASE INHIBITOR, DEPSIPEPTIDE (FR901228, NSC 630176), IN PATIENTS WITH REFRACTORY NEOPLASMS", CLINICAL CANCER RESEARCH, THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (200203), vol. 8, no. 3, ISSN 1078-0432, pages 718 - 728, XP009012362 [X] 60 * abstract *
 [X]  - "Human MDR1 related DNA sequence SEQ ID NO:674.", Geneseq, (20031204), Database accession no. ADB92124, URL: EBI, XP002443350 [X] 56,59 * the whole document *
 [X]  - "Human MDR1 related DNA sequence SEQ ID NO:673.", Geneseq, (20031204), Database accession no. ADB92123, URL: EBI, XP002443351 [X] 56,59 * the whole document *
 [A]  - MEISSNER KONRAD ET AL, "Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms", PHARMACOGENETICS, CHAPMAN & HALL, LONDON, GB, (200406), vol. 14, no. 6, ISSN 0960-314X, pages 381 - 385, XP009086699 [A] * abstract *

DOI:   http://dx.doi.org/10.1097/00008571-200406000-00007
 [PX]  - SHAH MANISHA H ET AL, "Cardiotoxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 1 JUL 2006, (20060701), vol. 12, no. 13, ISSN 1078-0432, pages 3997 - 4003, XP002443312 [PX] 60 * abstract *

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-05-2689
Examination   - John L. Marshall ET AL, "A phase I trial of Depsipeptide (FR901228) in patients with advanced cancer", Journal of Experimental Therapeutics and Oncology, (20021101), vol. 2, no. 6, doi:10.1046/j.1359-4117.2002.01039.x, ISSN 1359-4117, pages 325 - 332, XP055023132

DOI:   http://dx.doi.org/10.1046/j.1359-4117.2002.01039.x
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