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EP About this file: EP1862548

EP1862548 - Death domain containing receptor 4 (DR4 : death receptor 4), member of the TNF-receptor superfamily and binding to trail (APO2-L) [Right-click to bookmark this link]
Status	The application has been refused Status updated on 16.01.2015 Database last updated on 22.08.2024
Most recent event Tooltip	16.01.2015	Refusal of application	published on 18.02.2015 [2015/08]
Applicant(s)	For all designated states HUMAN GENOME SCIENCES, INC. 14200 Shady Grove Road Rockville, MD 20850 / US
	For all designated states THE REGENTS OF THE UNIVERSITY OF MICHIGAN 3003 South State Street Ann Arbor, Michigan 48109-1274 / US
	[2007/49]
Inventor(s)	01 / Gentz, Reiner L. 13404 Fairland Park Drive Silver Spring, MD 20904 / US
	02 / Ni, Jian 17815 Fair Lady Way Germantown, Maryland 20874 / US
	03 / Rosen, Craig A. 22400 Rolling Hill Road Laytonsville, MD 20882 / US
	04 / Dixit, Vishva M. 26750 Shady Oaks Court Los Altos Hills, CA 94022 / US
	05 / Pan, James G. Apartment 11 4124 Green Meadows Boulevard Ypsilanti, MI 48197 / US
	[2007/49]
Representative(s)	Vossius & Partner Patentanwälte Rechtsanwälte mbB Siebertstrasse 3 81675 München / DE
	[N/P]
Former [2008/35]	Vossius & Partner Siebertstrasse 3 81675 München / DE
Former [2007/49]	Vossius & Partner Siebertstrasse 4 81675 München / DE
Application number, filing date	07009954.4	27.01.1998
	[2007/49]
Priority number, date	US19970035722P	28.01.1997 Original published format: US 35722 P
	US19970037829P	05.02.1997 Original published format: US 37829 P
	[2007/49]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	EP1862548
	Date:	05.12.2007
	Language:	EN
	[2007/49]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	26.10.2007
Classification	IPC:	C12N15/12, C07K16/28, C07K14/705	[2007/49]
	CPC:	C07K14/70578 (EP,US)
Designated contracting states	AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2007/49]
Title	German:	Death-Domain-enthaltender Rezeptor 4 (DR4: Death receptor 4), Mitglied der TNF-Rezeptor-Superfamilie und Bindung an Trail (APO2-L)	[2007/49]
	English:	Death domain containing receptor 4 (DR4 : death receptor 4), member of the TNF-receptor superfamily and binding to trail (APO2-L)	[2007/49]
	French:	Domaine de la mort contenant le récepteur 4 (DR4 : récepteur de la mort 4), élément de la famille élargie des récepteurs TNF et liant la piste (APO2-L)	[2007/49]
Biological material	This application mentions deposited biological material, check the file for details
Examination procedure	02.06.2008	Amendment by applicant (claims and/or description)
	02.06.2008	Examination requested [2008/29]
	13.05.2009	Despatch of a communication from the examining division (Time limit: M06)
	12.11.2009	Reply to a communication from the examining division
	04.05.2011	Despatch of a communication from the examining division (Time limit: M04)
	14.09.2011	Reply to a communication from the examining division
	09.07.2012	Despatch of a communication from the examining division (Time limit: M04)
	19.11.2012	Reply to a communication from the examining division
	21.08.2014	Cancellation of oral proceeding that was planned for 17.09.2014
	17.09.2014	Date of oral proceedings (cancelled)
	02.10.2014	Despatch of communication that the application is refused, reason: substantive examination [2015/08]
	02.10.2014	Application refused, date of legal effect [2015/08]
Parent application(s) Tooltip	EP98904690.9 / EP1012274
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP19980904690) is 09.08.2004
Fees paid	Renewal fee
	18.05.2007	Renewal fee patent year 03
	18.05.2007	Renewal fee patent year 04
	18.05.2007	Renewal fee patent year 05
	18.05.2007	Renewal fee patent year 06
	18.05.2007	Renewal fee patent year 07
	18.05.2007	Renewal fee patent year 08
	18.05.2007	Renewal fee patent year 09
	18.05.2007	Renewal fee patent year 10
	25.01.2008	Renewal fee patent year 11
	30.01.2009	Renewal fee patent year 12
	25.01.2010	Renewal fee patent year 13
	25.01.2011	Renewal fee patent year 14
	25.01.2012	Renewal fee patent year 15
	08.01.2013	Renewal fee patent year 16
	08.01.2014	Renewal fee patent year 17
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[A]WO9701633 (IMMUNEX CORP [US]);
		[E]EP0857782 (SMITHKLINE BEECHAM CORP [US]) [E] 1-21* polypeptide designated death domain-1 corresponds to amino acids 365-468 of SEQ ID NO. 2. *;
		[E]WO9902653 (UNIV PENNSYLVANIA [US], et al) [E] 1-21 * SEQ ID NO. 2 is 100% identical over its entire length to GSP:AAW93609 from WO9902653 *;
		[E]WO9911791 (UNIV WASHINGTON [US]) [E] 1-21 * SEQ ID NO. 2 is 100% identical over its entire length to GSP:AAY31602 from WO9937684. *;
		[E]WO9937684 (GENENTECH INC [US]) [E] 1-21 * SEQ ID NO. 2 is 100% identical to GSP:AAW93577 from WO9911791 published on 19990311 over amino acid residues 59-468. *;
		[PX] - PAN G ET AL, "The receptor for the cytotoxic ligand TRAIL.", SCIENCE, APR 4 1997, 276 (5309) P111-3, UNITED STATES, (19970404), XP000676684 [PX] 1-21 * the whole document * DOI: http://dx.doi.org/10.1126/science.276.5309.111
		[X] - HIILIER ET AL., "The WasHU-Merck EST Project", EMBL NUCLEIC ACID DB, EBI, Hinxton, UK, (19961030), XP002067065 [X] 5,9-11,18 * abstract *
	by applicant	US4631211
		EP0394827
		WO9201810
		WO9409137
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