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Extract from the Register of European Patents

EP About this file: EP1980626

EP1980626 - Involvement of lipid kinase, and signal transduction pathway comprising said lipid kinase, in resistance to HER2-targeting therapy [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  25.09.2009
Database last updated on 16.11.2024
Most recent event   Tooltip25.09.2009Application deemed to be withdrawnpublished on 28.10.2009  [2009/44]
Applicant(s)For all designated states
Het Nederlands Kanker Instituut
Plesmanlaan 121
1066 CX Amsterdam / NL
[2008/42]
Inventor(s)01 / Berns, Katrien
Schaepmanlaan 1
2061 LX Bloemendaal / NL
02 / Bernards, René
Koningsvaren 37
1391 AD Abcoude / NL
 [2008/42]
Representative(s)van Loon, C.J.J., et al
Vereenigde
Johan de Wittlaan 7
2517 JR Den Haag / NL
[N/P]
Former [2008/42]van Loon, C.J.J., et al
Vereenigde Johan de Wittlaan 7
2517 JR Den Haag / NL
Application number, filing date07106144.413.04.2007
[2008/42]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1980626
Date:15.10.2008
Language:EN
[2008/42]
Search report(s)(Supplementary) European search report - dispatched on:EP10.10.2007
ClassificationIPC:C12Q1/68
[2008/42]
CPC:
C12Q1/6886 (EP,US); C12Q2600/106 (EP,US); C12Q2600/16 (EP,US);
C12Q2600/178 (EP,US)
Designated contracting states(deleted) [2009/26]
Former [2008/42]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:Lipidkinasebeteiligung und Signaltransduktionsweg mit besagter Lipidkinase als Resistenz gegen HER2-Targeting-Therapie[2008/42]
English:Involvement of lipid kinase, and signal transduction pathway comprising said lipid kinase, in resistance to HER2-targeting therapy[2008/42]
French:Implication de kinase de lipide, et passage de transduction du signal comportant cette kinase de lipide, en résistance à la thérapie de ciblage HER2[2008/42]
Examination procedure16.04.2009Application deemed to be withdrawn, date of legal effect  [2009/44]
15.06.2009Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2009/44]
Fees paidPenalty fee
Additional fee for renewal fee
30.04.200903   M06   Not yet paid
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Documents cited:Search[X]  - FUJITA T ET AL, "PTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancer", BRITISH JOURNAL OF CANCER, (200601), vol. 94, no. 2, ISSN 0007-0920, pages 247 - 252, XP002449978 [X] 1-7,9-11 * the whole document *

DOI:   http://dx.doi.org/10.1038/sj.bjc.6602926
 [X]  - NAGATA YOICHI ET AL, "PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients", CANCER CELL, (200408), vol. 6, no. 2, ISSN 1535-6108, pages 117 - 127, XP002449979 [X] 1-7,9-11 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.ccr.2004.06.022
 [A]  - MANO M S ET AL, "Exquisite antitumour response to trastuzumab in a patient with no evidence of Ras-Raf-MAPK and P13K-Akt pathways activation", BREAST, (200408), vol. 13, no. 4, ISSN 0960-9776, pages 347 - 349, XP002449980 [A] * the whole document *
 [A]  - DIERAS VERONIQUE ET AL, "Trastuzumab (Herceptin (R)) and breast cancer: mechanisms of resistance", BULLETIN DU CANCER (MONTROUGE), (200703), vol. 94, no. 3, ISSN 0007-4551, pages 259 - 266, XP008083431 [A] * the whole document *
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