blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP1978947

EP1978947 - NITROOXYDERIVATIVES FOR USE IN THE TREATMENT OF MUSCULAR DYSTROPHIES [Right-click to bookmark this link]
Former [2008/42]USE OF NITROOXYDERIVATIVE OF DRUG FOR THE TREATMENT OF MUSCULAR DYSTROPHIES
[2014/11]
StatusNo opposition filed within time limit
Status updated on  19.06.2015
Database last updated on 25.09.2024
Most recent event   Tooltip13.03.2020Change - lapse in a contracting state
State(s) deleted from list of lapses: TR
published on 15.04.2020  [2020/16]
Applicant(s)For all designated states
Nicox Science Ireland
Riverside One
Sir John Rogerson's Quay
Dublin 2 / IE
[2014/48]
Former [2014/32]For all designated states
Nicox S.A.
Drakkar 2, Bat D
2405 Route des Dolines
CS 10313 Sophia Antipolis - Valbonne / FR
Former [2008/42]For all designated states
NicOx S.A.
Taissounières HB4 1681 route des Dolines, BP 313
06560 Sophia Antipolis - Valbonne / FR
Inventor(s)01 / CLEMENTI, Emilio
Via Pindemonte 1
20129 Milano / IT
02 / COSSU, Giulio
Via Poerio 30
20129 Milano / IT
03 / BRUNELLI, Silvia
Via Pindemonte 1
20129 Milano / IT
04 / ONGINI, Ennio
Via Fratelli Cervi
Residenza Campo
I-20090 Segrate / IT
 [2014/33]
Former [2008/42]01 / CLEMENTI, Emilio
Via Pindemonte 1
20129 Milano / IT
02 / COSSU, Giulio
Via Poerio 30
20129 Milano / IT
03 / BRUNELLI, Silvia
Via Pindemonte 1
20129 Milano / IT
04 / ONGINI, Ennio
Via Fratelli Cervi Residenza Campo
I-20090 Segrate / IT
Representative(s)Barchielli, Giovanna, et al
Bianchetti & Minoja with
Trevisan & Cuonzo IPS Srl
Via Plinio, 63
20129 Milano / IT
[N/P]
Former [2012/19]Barchielli, Giovanna, et al
Bianchetti Bracco Minoja S.r.l.
Via Plinio, 63
20129 Milano / IT
Former [2008/42]Barchielli, Giovanna
Nicox Research Institute S.r.l., Patent Department, Via Ariosto, 21
20091 Bresso (Milano) / IT
Application number, filing date07712084.823.01.2007
[2008/42]
WO2007EP50630
Priority number, dateUS20060764755P03.02.2006         Original published format: US 764755 P
[2008/42]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007088123
Date:09.08.2007
Language:EN
[2007/32]
Type: A2 Application without search report 
No.:EP1978947
Date:15.10.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 09.08.2007 takes the place of the publication of the European patent application.
[2008/42]
Type: B1 Patent specification 
No.:EP1978947
Date:13.08.2014
Language:EN
[2014/33]
Search report(s)International search report - published on:EP20.09.2007
ClassificationIPC:A61K31/04, A61P21/00, A61K31/335, A61K31/38, A61K31/381, A61K31/401, A61K31/407, A61K31/415, A61K31/42, A61K31/436, A61K31/44, A61K31/505, A61K31/216, A61K31/235, A61K31/40, A61K31/404
[2014/11]
CPC:
A61K31/04 (EP,US); C07D209/52 (KR); A61K31/216 (EP,US);
A61K31/235 (EP,US); A61K31/335 (EP,US); A61K31/38 (EP,US);
A61K31/381 (EP,US); A61K31/40 (EP,US); A61K31/401 (EP,US);
A61K31/404 (EP,US); A61K31/407 (EP,US); A61K31/415 (EP,US);
A61K31/42 (EP,US); A61K31/436 (EP,US); A61K31/44 (EP,US);
A61K31/505 (EP,US); A61P21/00 (EP); A61P21/04 (EP);
A61P29/00 (EP); A61P43/00 (EP); C07D207/30 (KR) (-)
Former IPC [2008/42]A61K31/04, A61P21/00, A61K31/335, A61K31/38, A61K31/381, A61K31/401, A61K31/407, A61K31/415, A61K31/42, A61K31/436, A61K31/44, A61K31/505
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/42]
Extension statesAL08.07.2008
BA08.07.2008
HR08.07.2008
MK08.07.2008
RS08.07.2008
TitleGerman:NITROOXYDERIVATEN ZUR VERWENDUNG BEI DER BEHANDLUNG VON MUSKULÄRER DYSTROPHIEN[2014/11]
English:NITROOXYDERIVATIVES FOR USE IN THE TREATMENT OF MUSCULAR DYSTROPHIES[2014/11]
French:DÉRIVÉS NITRO-OXYDES POUR UTILISATION DANS LE TRAITEMENT DES DYSTROPHIES MUSCULAIRES[2014/11]
Former [2008/42]VERWENDUNG EINES NITROOXYDERIVATS EINES HEILMITTELS ZUR BEHANDLUNG MUSKULÄRER DYSTROPHIEN
Former [2008/42]USE OF NITROOXYDERIVATIVE OF DRUG FOR THE TREATMENT OF MUSCULAR DYSTROPHIES
Former [2008/42]UTILISATION DE DERIVES NITRO-OXYDES DE MEDICAMENTS POUR LE TRAITEMENT DE DYSTROPHIES MUSCULAIRES
Entry into regional phase08.07.2008National basic fee paid 
08.07.2008Designation fee(s) paid 
08.07.2008Examination fee paid 
Examination procedure08.07.2008Examination requested  [2008/42]
28.06.2012Despatch of a communication from the examining division (Time limit: M04)
05.11.2012Reply to a communication from the examining division
16.10.2013Despatch of a communication from the examining division (Time limit: M04)
27.01.2014Reply to a communication from the examining division
27.03.2014Communication of intention to grant the patent
07.07.2014Fee for grant paid
07.07.2014Fee for publishing/printing paid
07.07.2014Receipt of the translation of the claim(s)
Divisional application(s)EP14175223.8  / EP2786749
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  28.06.2012
Opposition(s)15.05.2015No opposition filed within time limit [2015/30]
Fees paidRenewal fee
08.07.2008Renewal fee patent year 03
25.01.2010Renewal fee patent year 04
25.01.2011Renewal fee patent year 05
25.01.2012Renewal fee patent year 06
28.01.2013Renewal fee patent year 07
24.01.2014Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCZ13.08.2014
EE13.08.2014
LV13.08.2014
SK13.08.2014
BG13.11.2014
IS13.12.2014
[2020/16]
Former [2020/15]CZ13.08.2014
EE13.08.2014
LV13.08.2014
SK13.08.2014
TR13.08.2014
BG13.11.2014
IS13.12.2014
Former [2015/23]CZ13.08.2014
EE13.08.2014
LV13.08.2014
SK13.08.2014
BG13.11.2014
IS13.12.2014
Former [2015/12]LV13.08.2014
BG13.11.2014
IS13.12.2014
Former [2015/10]BG13.11.2014
Cited inInternational search[DY]WO9530641  (NICOX LTD [IE], et al);
 [DY]WO0053191  (UNIV MANITOBA [CA], et al);
 [Y]EP1473288  (NICOX SA [FR]);
 [DY]WO2004105754  (NICOX SA [FR], et al);
 [Y]WO2005023305  (INPHARMATICA LTD [GB], et al);
Examination   - BRUNELLI SILVIA ET AL, "Nitric oxide release combined with nonsteroidal anti inflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES - PNAS, NATIONAL ACADEMY OF SCIENCES, US, (20070102), vol. 104, no. 1, doi:10.1073/PNAS.0608277104, ISSN 0027-8424, pages 264 - 269, XP002445669

DOI:   http://dx.doi.org/10.1073/pnas.0608277104
    - CLARA SCIORATI ET AL, "A dual acting compound releasing nitric oxide (NO) and ibuprofen, NCX 320, shows significant therapeutic effects in a mouse model of muscular dystrophy", PHARMACOLOGICAL RESEARCH, ACADEMIC PRESS, LONDON, GB, vol. 64, no. 3, doi:10.1016/J.PHRS.2011.05.003, ISSN 1043-6618, (20110505), pages 210 - 217, (20110512), XP028096923

DOI:   http://dx.doi.org/10.1016/j.phrs.2011.05.003
by applicantEP0759899
 WO0053191
 EP1194397
 WO2004105754
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.