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Extract from the Register of European Patents

EP About this file: EP1989220

EP1989220 - HIV FUSION INHIBITOR PEPTIDES WITH IMPROVED BIOLOGICAL PROPERTIES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.10.2012
Database last updated on 25.09.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU
published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
Synageva BioPharma Corp.
128 Spring Street, Suite 520
Lexington, MA 02421 / US
[2012/17]
Former [2011/12]For all designated states
Trimeris, Inc.
2530 Meridian Parkway, 2nd Floor
Durham, NC 27713 / US
Former [2008/46]For all designated states
Trimeris, Inc.
3500 Paramount Way
Morrisville, NC 27560 / US
Inventor(s)01 / DWYER, John
102 Buck Taylor Trail
Chapel Hill, NC 27516 / US
02 / BRAY, Brian, L.
1912 Broadway Drive
Graham, NC 27253 / US
03 / SCHNEIDER, Stephen, E.
7405 Baystone Court
Raleigh, NC 27615Raleigh, NC 27615 / US
04 / ZHANG, Huyi
604 Chancellors Ridge Dr.
Durham, NC 27713 / US
05 / TVERMOES, Nicolai, A.
6921 Calais Drive
Durham, NC 27712 / US
06 / JOHNSTON, Barbara, E.
6436 E. Lake Anne Drive
Raleigh, NC 27612 / US
07 / FRIEDRICH, Paul, E.
4208 Wyckford Place
Apex, NC 27539 / US
 [2011/49]
Former [2011/12]01 / DWYER, John
102 Buck Taylor Trail
Chapel Hill, NC 27516 / US
02 / BRAY, Brian, L.
1912 Broadway Drive
Graham, NC 27253 / US
03 / SCHNEIDER, Stephen, E.
7405 Baystone Court
Raleigh, NC 27615 / US
04 / ZHANG, Huyi
604 Chancellors Ridge Dr.
Durham, NC 27713 / US
05 / TVERMOES, Nicolai, A.
6921 Calais Drive
Durham, NC 27712 / US
06 / JOHNSTON, Barbara, E.
6436 E. Lake Anne Drive
Raleigh, NC 27612 / US
07 / FRIEDRICH, Paul, E.
4208 Wyckford Place
Apex, NC 27539 / US
Former [2008/46]01 / DWYER, John
102 Buck Taylor Trail
Chapel Hill, NC 27516 / US
02 / BRAY, Brian, L.
1912 Broadway Drive
Graham, NC 27253 / US
03 / SCHNEIDER, Stephen, E.
7612 Harps Mill Road
Raleigh, NC 27615 / US
04 / ZHANG, Huyi
604 Chancellors Ridge Dr.
Durham, NC 27713 / US
05 / TVERMOES, Nicolai, A.
6921 Calais Drive
Durham, NC 27712 / US
06 / JOHNSTON, Barbara, E.
6436 E. Lake Anne Drive
Raleigh, NC 27612 / US
07 / FRIEDRICH, Paul, E.
4208 Wyckford Place
Apex, NC 27539 / US
Representative(s)Weber, Martin, et al
Jones Day
Prinzregentenstrasse 11
80538 München / DE
[N/P]
Former [2008/46]Weber-Quitzau, Martin, et al
Jones Day Prinzregentenstrasse 11
80538 München / DE
Application number, filing date07749903.602.02.2007
[2008/46]
WO2007US02990
Priority number, dateUS20060764674P02.02.2006         Original published format: US 764674 P
[2008/46]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007097903
Date:30.08.2007
Language:EN
[2007/35]
Type: A2 Application without search report 
No.:EP1989220
Date:12.11.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 30.08.2007 takes the place of the publication of the European patent application.
[2008/46]
Type: B1 Patent specification 
No.:EP1989220
Date:14.12.2011
Language:EN
[2011/50]
Search report(s)International search report - published on:US22.05.2008
(Supplementary) European search report - dispatched on:EP03.04.2009
ClassificationIPC:C07K14/16
[2009/18]
CPC:
C07K14/005 (EP,US); A61P31/18 (EP); A61P43/00 (EP);
A61K38/00 (EP,US); C12N2740/16022 (EP,US); C12N2740/16122 (EP,US);
G01N2333/16 (EP,US); G01N2800/26 (EP,US) (-)
Former IPC [2008/46]C07K5/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/46]
Extension statesAL25.08.2008
BA25.08.2008
HR25.08.2008
MK25.08.2008
RS25.08.2008
TitleGerman:HIV-FUSIONSHEMMERPEPTIDE MIT VERBESSERTEN BIOLOGISCHEN EIGENSCHAFTEN[2008/46]
English:HIV FUSION INHIBITOR PEPTIDES WITH IMPROVED BIOLOGICAL PROPERTIES[2008/46]
French:PEPTIDES INHIBITEURS DE FUSION DU VIH À PROPRIÉTÉS BIOLOGIQUES AMÉLIORÉES[2008/46]
Entry into regional phase25.08.2008National basic fee paid 
25.08.2008Search fee paid 
25.08.2008Designation fee(s) paid 
25.08.2008Examination fee paid 
Examination procedure25.08.2008Examination requested  [2008/46]
23.10.2008Amendment by applicant (claims and/or description)
12.05.2009Despatch of a communication from the examining division (Time limit: M06)
23.11.2009Reply to a communication from the examining division
31.08.2010Despatch of a communication from the examining division (Time limit: M04)
02.12.2010Reply to a communication from the examining division
09.02.2011Communication of intention to grant the patent
20.05.2011Fee for grant paid
20.05.2011Fee for publishing/printing paid
30.06.2011Despatch of a communication from the examining division (Time limit: M04)
24.10.2011Reply to a communication from the examining division
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  12.05.2009
Opposition(s)17.09.2012No opposition filed within time limit [2012/47]
Fees paidRenewal fee
13.02.2009Renewal fee patent year 03
16.02.2010Renewal fee patent year 04
15.02.2011Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU02.02.2007
CZ14.12.2011
EE14.12.2011
LT14.12.2011
LV14.12.2011
PL14.12.2011
RO14.12.2011
SI14.12.2011
SK14.12.2011
TR14.12.2011
BG14.03.2012
IS14.04.2012
[2014/34]
Former [2014/21]CZ14.12.2011
EE14.12.2011
LT14.12.2011
LV14.12.2011
PL14.12.2011
RO14.12.2011
SI14.12.2011
SK14.12.2011
TR14.12.2011
BG14.03.2012
IS14.04.2012
Former [2012/37]CZ14.12.2011
EE14.12.2011
LT14.12.2011
LV14.12.2011
PL14.12.2011
RO14.12.2011
SI14.12.2011
SK14.12.2011
BG14.03.2012
IS14.04.2012
Former [2012/36]CZ14.12.2011
EE14.12.2011
LT14.12.2011
LV14.12.2011
RO14.12.2011
SI14.12.2011
SK14.12.2011
BG14.03.2012
IS14.04.2012
Former [2012/35]CZ14.12.2011
EE14.12.2011
LT14.12.2011
LV14.12.2011
SI14.12.2011
BG14.03.2012
IS14.04.2012
Former [2012/34]CZ14.12.2011
LT14.12.2011
LV14.12.2011
SI14.12.2011
IS14.04.2012
Former [2012/25]LT14.12.2011
LV14.12.2011
SI14.12.2011
Former [2012/20]LT14.12.2011
Documents cited:Search[X]WO2005067960  (TRIMERIS INC [US], et al) [X] 1-35 * page 7, line 11 - line 31*; page 3, line 35 - page 5, line 33; claims 1-34; sequences 51,54,92 *;
 [X]WO2005089796  (TRIMERIS INC [US], et al) [X] 1-35 * page 4 - page 8; claims 1-34; sequences 133, 170 *;
 [PX]US2006247416  (DELMEDICO MARY K [US], et al) [PX] 1-35* claims 1-66; sequence 97 *;
 [A]  - GALLO S A ET AL, "The HIV Env-mediated fusion reaction", BIOCHIMICA ET BIOPHYSICA ACTA. BIOMEMBRANES, AMSTERDAM, NL, (20030711), vol. 1614, no. 1, ISSN 0005-2736, pages 36 - 50, XP004438798 [A] * the whole document *

DOI:   http://dx.doi.org/10.1016/S0005-2736(03)00161-5
 [A]  - LIU ET AL, "An artificial HIV enhancer-binding peptide is dimerized by the addition of a leucine zipper", EUROPEAN BIOPHYSICS JOURNAL, SPRINGER, TOKYO, JP, (19970101), vol. 25, no. 5/06, ISSN 0175-7571, pages 399 - 403, XP002091419 [A] * abstract *

DOI:   http://dx.doi.org/10.1007/s002490050052
 [A]  - JOYCE JG ET AL., "Enhancement of .alpha.-Helicity in the HIV-1 Inhibitory Peptide DP178 Leads to an Increased Affinity for Human Monoclonal Antibody 2F5 but Does Not Elicit Neutralizing Responses in Vitro", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (20021129), vol. 277, no. 48, pages 45811 - 45820, XP002520853 [A] * abstract *

DOI:   http://dx.doi.org/10.1074/JBC.M205862200
International search[A]  - LALEZARI ET AL., "Enfuvirtide, an HIV-1 Fusion Inhibitor, for Drug-Resistant HIV Infection in North and South America", N. ENGL. J. MED., (2003), pages 1 - 10, XP008130410
 [A]  - EXPERT OPIN. THER. PATENTS, (2004), vol. 14, no. 5, pages 733 - 748, XP008130208
by applicantUS6258782
 WO2005067960
    - KILBY ET AL., NATURE MED., (1998), vol. 4, pages 1302 - 1307
    - MELBY ET AL., AIDS RESEARCH AND HUMAN RETROVIRUSES, (2006), vol. 22, no. 5, pages 375 - 385
    - GREENBERG; CAMMACK, J. ANTIMICROBIAL CHEMOTHERAPY, (2004), vol. 54, pages 333 - 340
    - SISTA ET AL., AIDS, (2004), vol. 18, pages 1787 - 1794
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.