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Extract from the Register of European Patents

EP About this file: EP1993530

EP1993530 - USE OF DHA AND ARA IN THE PREPARATION OF A COMPOSITION FOR REGULATING GENE EXPRESSION [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  06.05.2011
Database last updated on 13.09.2024
Most recent event   Tooltip06.05.2011Withdrawal of applicationpublished on 08.06.2011  [2011/23]
Applicant(s)For all designated states
Mead Johnson Nutrition Company
2400 West Lloyd Expressway
Evansville, IN 47721-0001 / US
For all designated states
Cornell Research Foundation, Inc.
20 Thornwood Drive, Suite 105
Ithaca, NY 14850 / US
[2009/36]
Former [2008/48]For all designated states
Bristol-Myers Squibb Company
Lawrenceville-Princeton Road
Princeton NJ 08543-4000 / US
For all designated states
Cornell Research Foundation, Inc.
20 Thornwood Drive, Suite 105
Ithaca, NY 14850 / US
Inventor(s)01 / JOUNI, Zeina
Bristol-myers Squibb Company - Mead Johnson 2400 West Lloyd Expressway
Evansville, IN 47721 / US
02 / BRENNA, J., Thomas
32 Deerhaven Drive
Ithaca, NY 14850 / US
03 / ANTHONY, Joshua, C.
Bristol-myers Squibb Company - Mead Johnson 2400 West Lloyd Expressway
Evansville, IN 47721 / US
04 / KOTHAPALLI, Kumar Sesha Durga
201 Maple Avenue
Ithaca, NY 14850 / US
05 / RUMSEY, Steven, C.
Rua Pasteur, 260 Apt. 401
Curitiba, PR / BR
06 / RAI, Deshanie
Bristol-myers Squibb Company - Mead Johnson 2400 West Lloyd Expressway
Evansville, IN 47721 / US
 [2008/48]
Representative(s)Prins, Adrianus Willem, et al
V.O.
Johan de Wittlaan 7
2517 JR Den Haag / NL
[N/P]
Former [2010/34]Prins, Adrianus Willem, et al
Vereenigde Johan de Wittlaan 7
2517 JR Den Haag / NL
Former [2009/36]Modiano, Micaela Nadia, et al
Modiano Josif Pisanty & Staub Ltd Thierschstrasse 11
80538 München / DE
Former [2008/48]Modiano, Micaela Nadia, et al
Modiano Josif Pisanty & Staub Ltd Thierschstrasse 11
80538 München / DE
Application number, filing date07751225.921.02.2007
[2008/48]
WO2007US04451
Priority number, dateUS20060777724P28.02.2006         Original published format: US 777724 P
[2008/48]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007100566
Date:07.09.2007
Language:EN
[2007/36]
Type: A2 Application without search report 
No.:EP1993530
Date:26.11.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 07.09.2007 takes the place of the publication of the European patent application.
[2008/48]
Search report(s)International search report - published on:EP09.10.2008
ClassificationIPC:A61K31/202, A61P3/06, A61P9/00, A61P11/00, A61P25/28, A61P27/02, A61P37/02, A61P35/00, A61P3/10
[2008/48]
CPC:
A61K31/202 (EP,KR,US); A61P11/00 (EP); A61P25/00 (EP);
A61P25/28 (EP); A61P27/02 (EP); A61P3/00 (EP);
A61P3/06 (EP); A61P3/10 (EP); A61P35/00 (EP);
A61P37/00 (EP); A61P37/02 (EP); A61P9/00 (EP) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/48]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:VERWENDUNG VON DHA UND ARA BEI DER HERSTELLUNG EINER ZUSAMMENSETZUNG ZUR REGULIERUNG DER GENEXPRESSION[2008/48]
English:USE OF DHA AND ARA IN THE PREPARATION OF A COMPOSITION FOR REGULATING GENE EXPRESSION[2008/48]
French:UTILISATION DE DHA ET D'ARA DANS LA PRÉPARATION D'UNE COMPOSITION PERMETTANT DE RÉGULER L'EXPRESSION GÉNIQUE[2008/48]
Entry into regional phase26.09.2008National basic fee paid 
26.09.2008Designation fee(s) paid 
26.09.2008Examination fee paid 
Examination procedure26.09.2008Examination requested  [2008/48]
04.12.2008Amendment by applicant (claims and/or description)
10.03.2009Despatch of a communication from the examining division (Time limit: M06)
18.09.2009Reply to a communication from the examining division
07.04.2010Despatch of a communication from the examining division (Time limit: M04)
04.08.2010Reply to a communication from the examining division
02.05.2011Application withdrawn by applicant  [2011/23]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  10.03.2009
Fees paidRenewal fee
13.02.2009Renewal fee patent year 03
16.02.2010Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
28.02.201105   M06   Not yet paid
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See the Register of the Unified Patent Court for opt-out data
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Cited inInternational search[A]WO02068687  (GENEMEDIX PLC [GB], et al) [A] 1-27,40-52 * figures 1,2; example - *;
 [Y]US2005043405  (FRITSCH DALE A [US], et al) [Y] 1-27,40-52 * claim -; tables 6,8 *;
 [Y]WO2005037848  (ENZYMOTEC LTD [IL], et al) [Y] 1-27,40-52 * page 40, paragraph 1; claim - *;
 [DY]  - BERGER ALVIN ET AL, "Dietary effects of arachidonate-rich fungal oil and fish oil on murine hepatic and hippocampal gene expression", LIPIDS IN HEALTH AND DISEASE, BIOMED CENTRAL, LONDON, GB, (20021021), vol. 1, no. 1, ISSN 1476-511X, page 2, XP021018308 [DY] 1-27,40-52 * Chapter: Gene expression analysis, Conclusions and key findings, Materials;; table 2 *

DOI:   http://dx.doi.org/10.1186/1476-511X-1-2
 [PX]  - KOTHAPALLI K S D ET AL, "Comprehensive differential transcriptome analysis of cerebral cortex of baboon neonates consuming arachidonic acid and moderate and high docosahexaenoic acid formulas", FASEB JOURNAL, & EXPERIMENTAL BIOLOGY 2006 MEETING; SAN FRANCISCO, CA, USA; APRIL 01 05, 2006, (200603), vol. 20, no. 5, Part 2, ISSN 0892-6638, page A1347, XP002475656 [PX] 1-27,40-52 * the whole document *
 [T]  - KOTHAPALLI KUMAR S D ET AL, "Differential cerebral cortex transcriptomes of baboon neonates consuming moderate and high docosahexaenoic acid formulas.", PLOS ONE 2007, (2007), vol. 2, no. 4, ISSN 1932-6203, page e370, XP002475657 [T] * the whole document *

DOI:   http://dx.doi.org/10.1371/journal.pone.0000370
 [Y]  - DELLA RAGIONE A F ET AL, "Genes modulated by histone acetylation as new effectors of butyrate activity", FEBS LETTERS, ELSEVIER, AMSTERDAM, NL, (20010622), vol. 499, no. 3, ISSN 0014-5793, pages 199 - 204, XP004247015 [Y] 1-27,40-52 * page 201, column 2, paragraph 2; figure 1 *

DOI:   http://dx.doi.org/10.1016/S0014-5793(01)02539-X
 [X]  - TSAI WEN-SY ET AL, "Inhibitory effects of n-3 polyunsaturated fatty acids on sigmoid colon cancer transformants", JOURNAL OF GASTROENTEROLOGY, (199804), vol. 33, no. 2, ISSN 0944-1174, pages 206 - 212, XP002475658 [X] 1-27,40-52 * abstract *
 [X]  - MENENDEZ JAVIER A ET AL, "Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: A novel me", INTERNATIONAL JOURNAL OF ONCOLOGY, (200406), vol. 24, no. 6, ISSN 1019-6439, pages 1369 - 1383, XP009097853 [X] 1-27,40-52 * abstract *
 [DY]  - YOSHIDA YUTAKA ET AL, "Mice lacking a transcriptional corepressor Tob are predisposed to cancer.", GENES AND DEVELOPMENT, (20030515), vol. 17, no. 10, ISSN 0890-9369, pages 1201 - 1206, XP002475659 [DY] 1-27,40-52 * abstract *

DOI:   http://dx.doi.org/10.1101/gad.1088003
 [X]  - BERGER ALVIN ET AL, "Unraveling lipid metabolism with microarrays: effects of arachidonate and docosahexaenoate acid on murine hepatic and hippocampal gene expression.", GENOME BIOLOGY 23 MAY 2002, (20020523), vol. 3, no. 7, ISSN 1465-6914, page PREPRINT0004, XP009097855 [X] 1-27,40-52 * the whole document *
 [Y]  - INNIS SHELA M, "Perinatal biochemistry and physiology of long-chain polyunsaturated fatty acids.", JOURNAL OF PEDIATRICS, (200310), vol. 143, no. 4 Supplement, ISSN 0022-3476, pages S1 - S8, XP009097749 [Y] 1-27,40-52 * page S1, paragraph 1 - page S2, paragraph 2 *

DOI:   http://dx.doi.org/10.1067/S0022-3476(03)00396-2
 [Y]  - WAINWRIGHT P E ET AL, "ARACHIDONIC ACID OFFSETS THE EFFECTS ON MOUSE BRAIN AND BEHAVIOR OF A DIET WITH A LOW (N-6):(N-3) RATIO AND VERY HIGH LEVELS OF DOCOSAHEXAENOIC ACID", JOURNAL OF NUTRITION, WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PA,, US, (1997), vol. 127, ISSN 0022-3166, pages 184 - 193, XP002950179 [Y] 1-27,40-52 * page 192, column 1, paragraph 3 - column 2, paragraph 2; figures 3,4 *
 [DY]  - JIN M ET AL, "The negative cell cycle regulator, Tob (transducer of ErbB-2), is a multifunctional protein involved in hippocampus-dependent learning and memory", NEUROSCIENCE, NEW YORK, NY, US, (2005), vol. 131, no. 3, ISSN 0306-4522, pages 647 - 659, XP004760726 [DY] 1-27,40-52 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.neuroscience.2004.10.044
 [DXP]  - KOTANI ET AL, "Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dysfunction", NEUROSCIENCE RESEARCH, ELSEVIER, SHANNON, IR, (200610), vol. 56, no. 2, ISSN 0168-0102, pages 159 - 164, XP005657071 [DXP] 1-27,40-52 * abstract *

DOI:   http://dx.doi.org/10.1016/j.neures.2006.06.010
 [Y]  - YAQOOB P, "Lipids and the immune response: From molecular mechanisms to clinical applications", CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE 200303 US, (200303), vol. 6, no. 2, ISSN 1363-1950, pages 133 - 150, XP009097854 [Y] 1-27,40-52 * the whole document *

DOI:   http://dx.doi.org/10.1097/00075197-200303000-00002
 [DY]  - GEBAUER MATHIAS ET AL, "Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage", ARTHRITIS RESEARCH, CURRENT SCIENCE, LONDON,, GB, (20050111), vol. 7, no. 2, ISSN 1465-9905, pages R274 - R284, XP021011562 [DY] 1-27,40-52 * abstract *

DOI:   http://dx.doi.org/10.1186/ar1479
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.