EP1999148 - HUMANIZED ANTI-CD22 ANTIBODIES AND THEIR USE IN TREATMENT OF ONCOLOGY, TRANSPLANTATION AND AUTOIMMUNE DISEASE [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 31.10.2014 Database last updated on 22.08.2024 | Most recent event Tooltip | 15.07.2016 | Lapse of the patent in a contracting state New state(s): TR | published on 17.08.2016 [2016/33] | Applicant(s) | For all designated states MedImmune, LLC One MedImmune Way Gaithersburg, MD 20878 / US | [2014/04] |
Former [2013/52] | For all designated states Aeres Biomedical Limited 1-3 Burtonhole Lane, Mill Hill London NW7 1AD / GB | ||
Former [2008/50] | For all designated states Aeres Biomedical Limited 1-3 Burtonhole Lane, Mill Hill London NW7 1AD / GB | Inventor(s) | 01 /
JONES, Tarran 1 Christchurch Crescent Radlett Hertforshire WD7 8AG / GB | 02 /
WILLIAMS, David, G. 56 White Horse Drive Epsom Surrey KT18 7LY / GB | [2013/52] |
Former [2008/50] | 01 /
JONES, Tarran 1 Christchurch Crescent Radlett Hertforshire WD7 8AG / GB | ||
02 /
WILLIAMS, David, G. 56 White Horse Drive Epsom Surrey KT18 7LY / GB | Representative(s) | Gibbs, Richard Marks & Clerk LLP The Beacon 176 St Vincent Street Glasgow G2 5SG / GB | [N/P] |
Former [2013/44] | Gibbs, Richard Marks & Clerk LLP Aurora 120 Bothwell Street Glasgow G2 7JS / GB | ||
Former [2008/50] | Weber, Martin, et al Jones Day Prinzregentenstrasse 11 80538 München / DE | Application number, filing date | 07752572.3 | 06.03.2007 | [2008/50] | WO2007US05883 | Priority number, date | US20060779804P | 06.03.2006 Original published format: US 779804 P | [2008/50] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2007103469 | Date: | 13.09.2007 | Language: | EN | [2007/37] | Type: | A2 Application without search report | No.: | EP1999148 | Date: | 10.12.2008 | Language: | EN | The application published by WIPO in one of the EPO official languages on 13.09.2007 takes the place of the publication of the European patent application. | [2008/50] | Type: | B1 Patent specification | No.: | EP1999148 | Date: | 25.12.2013 | Language: | EN | [2013/52] | Type: | B8 Corrected title page of specification | No.: | EP1999148 | Date: | 05.03.2014 | [2014/10] | Search report(s) | International search report - published on: | US | 16.10.2008 | (Supplementary) European search report - dispatched on: | EP | 15.04.2010 | Classification | IPC: | C07K16/00, C12P21/08, C07K1/00, C07K16/28, C07K16/46, A61K39/395, A61P35/00 | [2010/19] | CPC: |
C07K16/2803 (EP,US);
C07K16/2851 (US);
A61P35/00 (EP);
A61P37/00 (EP);
A61P37/06 (EP);
C07K16/465 (EP,US);
A61K2039/505 (EP,US);
C07K2317/24 (EP,US);
C07K2317/565 (EP,US);
C07K2317/567 (EP,US);
C07K2317/732 (EP,US);
C07K2317/734 (EP,US);
|
Former IPC [2008/50] | C07K16/00, C12P21/08, C07K1/00 | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR [2008/50] | Extension states | AL | 02.10.2008 | BA | 02.10.2008 | HR | 02.10.2008 | MK | 02.10.2008 | RS | 02.10.2008 | Title | German: | HUMANISIERTE ANTI-CD22-ANTIKÖRPER UND IHRE VERWENDUNG FÜR DIE BEHANDLUNG VON KREBS, TRANSPLANTATIONEN UND AUTOIMMUNERKRANKUNGEN | [2008/50] | English: | HUMANIZED ANTI-CD22 ANTIBODIES AND THEIR USE IN TREATMENT OF ONCOLOGY, TRANSPLANTATION AND AUTOIMMUNE DISEASE | [2008/50] | French: | ANTICORPS HUMANISÉS DIRIGÉS CONTRE L'ANTIGÈNE CD22 ET LEUR UTILISATION À DES FINS THÉRAPEUTIQUES EN ONCOLOGIE, AINSI QUE DANS LE CADRE DE TRANSPLANTATIONS ET DE MALADIES AUTO-IMMUNES | [2013/31] |
Former [2008/50] | ANTICORPS ANTI-CD22 HUMANISÉS ET LEUR UTILISATION DANS UN TRAITEMENT ONCOLOGIQUE, D'UNE TRANSPLANTATION ET D'UNE MALADIE AUTO-IMMUNE | Entry into regional phase | 02.10.2008 | National basic fee paid | 02.10.2008 | Search fee paid | 02.10.2008 | Designation fee(s) paid | 02.10.2008 | Examination fee paid | Examination procedure | 02.10.2008 | Examination requested [2008/50] | 08.12.2008 | Amendment by applicant (claims and/or description) | 13.07.2010 | Despatch of a communication from the examining division (Time limit: M06) | 24.01.2011 | Reply to a communication from the examining division | 06.06.2011 | Despatch of a communication from the examining division (Time limit: M06) | 15.12.2011 | Reply to a communication from the examining division | 09.07.2012 | Despatch of a communication from the examining division (Time limit: M06) | 18.01.2013 | Reply to a communication from the examining division | 18.07.2013 | Communication of intention to grant the patent | 11.11.2013 | Fee for grant paid | 11.11.2013 | Fee for publishing/printing paid | Divisional application(s) | EP12175725.6 / EP2540741 | EP13170804.2 / EP2650306 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 13.07.2010 | Opposition(s) | 26.09.2014 | No opposition filed within time limit [2014/49] | Fees paid | Renewal fee | 13.03.2009 | Renewal fee patent year 03 | 15.03.2010 | Renewal fee patent year 04 | 15.03.2011 | Renewal fee patent year 05 | 14.03.2012 | Renewal fee patent year 06 | 11.03.2013 | Renewal fee patent year 07 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 06.03.2007 | AT | 25.12.2013 | BE | 25.12.2013 | BG | 25.12.2013 | CY | 25.12.2013 | CZ | 25.12.2013 | DK | 25.12.2013 | EE | 25.12.2013 | ES | 25.12.2013 | FI | 25.12.2013 | IT | 25.12.2013 | LT | 25.12.2013 | LV | 25.12.2013 | MC | 25.12.2013 | MT | 25.12.2013 | NL | 25.12.2013 | PL | 25.12.2013 | RO | 25.12.2013 | SE | 25.12.2013 | SI | 25.12.2013 | SK | 25.12.2013 | TR | 25.12.2013 | LU | 06.03.2014 | GR | 26.03.2014 | CH | 31.03.2014 | LI | 31.03.2014 | IS | 25.04.2014 | PT | 28.04.2014 | [2016/33] |
Former [2016/32] | HU | 06.03.2007 | |
AT | 25.12.2013 | ||
BE | 25.12.2013 | ||
BG | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
IT | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
MC | 25.12.2013 | ||
MT | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SI | 25.12.2013 | ||
SK | 25.12.2013 | ||
LU | 06.03.2014 | ||
GR | 26.03.2014 | ||
CH | 31.03.2014 | ||
LI | 31.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2016/29] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
BG | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
IT | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
MC | 25.12.2013 | ||
MT | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SI | 25.12.2013 | ||
SK | 25.12.2013 | ||
LU | 06.03.2014 | ||
GR | 26.03.2014 | ||
CH | 31.03.2014 | ||
LI | 31.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2016/28] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
BG | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
MC | 25.12.2013 | ||
MT | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SI | 25.12.2013 | ||
SK | 25.12.2013 | ||
LU | 06.03.2014 | ||
GR | 26.03.2014 | ||
CH | 31.03.2014 | ||
LI | 31.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2016/27] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
BG | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
MC | 25.12.2013 | ||
MT | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SI | 25.12.2013 | ||
SK | 25.12.2013 | ||
LU | 06.03.2014 | ||
CH | 31.03.2014 | ||
LI | 31.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2016/25] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
BG | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
MT | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SI | 25.12.2013 | ||
SK | 25.12.2013 | ||
LU | 06.03.2014 | ||
CH | 31.03.2014 | ||
LI | 31.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2016/12] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
MT | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SI | 25.12.2013 | ||
SK | 25.12.2013 | ||
LU | 06.03.2014 | ||
CH | 31.03.2014 | ||
LI | 31.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2016/07] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SI | 25.12.2013 | ||
SK | 25.12.2013 | ||
LU | 06.03.2014 | ||
CH | 31.03.2014 | ||
LI | 31.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2015/24] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SI | 25.12.2013 | ||
SK | 25.12.2013 | ||
IE | 06.03.2014 | ||
LU | 06.03.2014 | ||
CH | 31.03.2014 | ||
LI | 31.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2015/08] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SK | 25.12.2013 | ||
IE | 06.03.2014 | ||
LU | 06.03.2014 | ||
CH | 31.03.2014 | ||
LI | 31.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2015/07] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SK | 25.12.2013 | ||
IE | 06.03.2014 | ||
LU | 06.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2014/48] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
DK | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SK | 25.12.2013 | ||
LU | 06.03.2014 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2014/39] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
NL | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SK | 25.12.2013 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2014/37] | AT | 25.12.2013 | |
BE | 25.12.2013 | ||
CY | 25.12.2013 | ||
CZ | 25.12.2013 | ||
EE | 25.12.2013 | ||
ES | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
PL | 25.12.2013 | ||
RO | 25.12.2013 | ||
SE | 25.12.2013 | ||
SK | 25.12.2013 | ||
IS | 25.04.2014 | ||
PT | 28.04.2014 | ||
Former [2014/36] | BE | 25.12.2013 | |
EE | 25.12.2013 | ||
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
SE | 25.12.2013 | ||
IS | 25.04.2014 | ||
Former [2014/34] | BE | 25.12.2013 | |
FI | 25.12.2013 | ||
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
SE | 25.12.2013 | ||
Former [2014/25] | FI | 25.12.2013 | |
LT | 25.12.2013 | ||
LV | 25.12.2013 | ||
SE | 25.12.2013 | ||
Former [2014/22] | FI | 25.12.2013 | |
LT | 25.12.2013 | ||
SE | 25.12.2013 | ||
Former [2014/20] | LT | 25.12.2013 | Documents cited: | Search | [I]WO9427638 (DANA FARBER CANCER INST INC [US]) [I] 1-26 * page 12, line 9 - page 13, line 15; claims 6-7; tables 2,3 *; | WO03072736 [ ] (UNIV DUKE [US], et al); | [IY]US2003202975 (TEDDER THOMAS F [US]) [I] 1-26 * paragraph [0157]; example 2; claims 1-38 * [Y] 1-26; | [Y]WO03093320 (CELLTECH R&D LTD [GB], et al) [Y] 1-26* example 2; claims 1-45 *; | [I]US2004001828 (TUSCANO JOSEPH [US], et al) [I] 1-26 * example 2; claims 1-37 *; | [A]US2005118182 (PASTAN IRA H [US], et al) [A] 1-26 * claims 1-44 *; | [T]WO2007103470 (MEDIMMUNE INC [US], et al) [T] * the whole document *; | [ID] - TUSCANO JOSEPH M ET AL, "Anti-CD22 ligand-blocking antibody HB22.7 has independent lymphomacidal properties and augments the efficacy of 90Y-DOTA-peptide-Lym-1 in lymphoma xenografts.", BLOOD 1 MAY 2003, (20030501), vol. 101, no. 9, ISSN 0006-4971, pages 3641 - 3647, XP002540281 [ID] 1-26 * page 3642, column left, paragraph last; figures 2,3; table 2 * DOI: http://dx.doi.org/10.1182/blood-2002-08-2629 | [T] - O'DONNELL ROBERT T ET AL, "Treatment of non-Hodgkin's lymphoma xenografts with the HB22.7 anti-CD22 monoclonal antibody and phosphatase inhibitors improves efficacy.", CANCER IMMUNOLOGY, IMMUNOTHERAPY : CII OCT 2009, (200910), vol. 58, no. 10, ISSN 1432-0851, pages 1715 - 1722, XP002540282 [T] * the whole document * DOI: http://dx.doi.org/10.1007/s00262-009-0688-5 | [I] - ENGEL P ET AL, "THE SAME EPITOPE ON CD22 OF LYMPHOCYTES MEDIATES THE ADHESION OF ERYTHROCYTES, T AND B LYMPHOCYTES, NEUTROPHILS, AND MONOCYTES", JOURNAL OF IMMUNOLOGY, AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, (19930601), vol. 150, no. 11, ISSN 0022-1767, pages 4719 - 4732, XP000999233 [I] 1-26 * page 4720, paragraph last - column right, paragraph 1 * * page 4723, column r, paragraph 3 - page 4725, column r, paragraph 1; tables 1,2 * | International search | [A]US2004001828 (TUSCANO JOSEPH [US], et al); | [A] - ENGEL P. ET AL., "IDENTIFICATION OF THE LIGAND-BINDING DORMAINS OF CD22, A MEMBER OF THE IMMUNOGLOBULIN SUPERFAMILY THAT UNIQUELY BINDS A SIALIC ACID-DEPENDENT LIGAND", J. EXP. MED., (19950401), vol. 181, no. 4, pages 1581 - 1586, XP001005276 DOI: http://dx.doi.org/10.1084/jem.181.4.1581 |