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Extract from the Register of European Patents

EP About this file: EP1991246

EP1991246 - TREATMENT OF DEVELOPMENT-RELATED DISORDERS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.07.2014
Database last updated on 27.07.2024
Most recent event   Tooltip15.07.2016Lapse of the patent in a contracting state
New state(s): TR		published on 17.08.2016  [2016/33]
Applicant(s)For all designated states
Zhu, Zhenglun
85 Brainerd Road, TH 3
Allston, MA 02134 / US
For all designated states
Gao, Hong
85 Brainerd Street TH3
Allston, MA 02134 / US
[2008/47]
Inventor(s)01 / see applicant
...
 [2008/47]
Representative(s)Purdy, Hugh Barry
PurdyLucey
Intellectual Property Limited
6-7 Harcourt Terrace
D02 FH73 Dublin 2 / IE
[N/P]
Former [2014/02]Purdy, Hugh Barry
PurdyLucey
Intellectual Property
6-7 Harcourt Terrace
D2 Dublin / IE
Former [2013/37]Brookes Batchellor LLP
46 Chancery Lane
London WC2A 1JE / GB
Former [2009/31]Brookes Batchellor LLP
102-108 Clerkenwell Road London
EC1M 5SA / GB
Former [2008/47]Brookes Batchellor LLP
102-108 Clerkenwell Road
London EC1M 5SA / GB
Application number, filing date07757336.822.02.2007
[2008/47]
WO2007US62587
Priority number, dateUS20060775645P22.02.2006         Original published format: US 775645 P
[2008/47]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007101063
Date:07.09.2007
Language:EN
[2007/36]
Type: A2 Application without search report 
No.:EP1991246
Date:19.11.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 07.09.2007 takes the place of the publication of the European patent application.
[2008/47]
Type: B1 Patent specification 
No.:EP1991246
Date:11.09.2013
Language:EN
[2013/37]
Search report(s)International search report - published on:US06.11.2008
(Supplementary) European search report - dispatched on:EP20.01.2010
ClassificationIPC:A61K38/00, A61P35/00, A61P37/02, C07H21/04, C07K14/32, C07K14/435, C12N15/85, C12N5/00, C12N5/07, C12P21/06, C12Q1/68, G01N33/53, G01N33/567
[2013/18]
CPC:
C07K14/463 (EP,CN,US); C12Q1/6886 (US); A61P29/00 (EP);
A61P3/00 (EP); A61P35/00 (EP); A61P37/02 (EP);
C07K14/4702 (EP,CN,US); G01N33/53 (CN); G01N33/68 (CN);
A61K38/00 (EP,CN,US) (-)
Former IPC [2008/52]A61K38/00, A61P35/00, A61P37/02, C07H21/04, C07K14/32, C07K14/435, C12N15/85, C12N5/00, C12N5/06, C12P21/06, C12Q1/68, G01N33/53, G01N33/567
Former IPC [2008/47]A61K38/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/47]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:BEHANDLUNG VON ENTWICKLUNGSBEDINGTEN STÖRUNGEN[2008/47]
English:TREATMENT OF DEVELOPMENT-RELATED DISORDERS[2008/47]
French:TRAITEMENT DE TROUBLES LIÉS AU DÉVELOPPEMENT[2008/47]
Entry into regional phase16.09.2008National basic fee paid 
16.09.2008Search fee paid 
16.09.2008Designation fee(s) paid 
16.09.2008Examination fee paid 
Examination procedure16.09.2008Amendment by applicant (claims and/or description)
16.09.2008Examination requested  [2008/47]
20.05.2010Despatch of a communication from the examining division (Time limit: M06)
30.11.2010Reply to a communication from the examining division
30.03.2011Despatch of a communication from the examining division (Time limit: M04)
25.07.2011Reply to a communication from the examining division
20.02.2012Despatch of a communication from the examining division (Time limit: M02)
24.04.2012Reply to a communication from the examining division
02.04.2013Communication of intention to grant the patent
31.07.2013Fee for grant paid
31.07.2013Fee for publishing/printing paid
Divisional application(s)EP12168755.2  / EP2612675
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  20.05.2010
Opposition(s)12.06.2014No opposition filed within time limit [2014/34]
Fees paidRenewal fee
26.02.2009Renewal fee patent year 03
24.02.2010Renewal fee patent year 04
23.02.2011Renewal fee patent year 05
24.02.2012Renewal fee patent year 06
27.02.2013Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU22.02.2007
AT11.09.2013
BE11.09.2013
BG11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
LT11.09.2013
LV11.09.2013
MC11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
TR11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
IE22.02.2014
LU22.02.2014
CH28.02.2014
LI28.02.2014
[2016/33]
Former [2016/32]HU22.02.2007
AT11.09.2013
BE11.09.2013
BG11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
LT11.09.2013
LV11.09.2013
MC11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
IE22.02.2014
LU22.02.2014
CH28.02.2014
LI28.02.2014
Former [2016/25]AT11.09.2013
BE11.09.2013
BG11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
LT11.09.2013
LV11.09.2013
MC11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
IE22.02.2014
LU22.02.2014
CH28.02.2014
LI28.02.2014
Former [2015/07]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
LT11.09.2013
LV11.09.2013
MC11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
IE22.02.2014
LU22.02.2014
CH28.02.2014
LI28.02.2014
Former [2014/46]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
LT11.09.2013
LV11.09.2013
MC11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
LU22.02.2014
CH28.02.2014
LI28.02.2014
Former [2014/44]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
LT11.09.2013
LV11.09.2013
MC11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
LU22.02.2014
Former [2014/41]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
DK11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
Former [2014/38]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
IT11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
Former [2014/28]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
PT13.01.2014
Former [2014/24]AT11.09.2013
BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
ES11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
PL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
Former [2014/23]BE11.09.2013
CY11.09.2013
CZ11.09.2013
EE11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
SK11.09.2013
GR12.12.2013
IS11.01.2014
Former [2014/22]BE11.09.2013
CY11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
NL11.09.2013
RO11.09.2013
SE11.09.2013
SI11.09.2013
GR12.12.2013
Former [2014/18]BE11.09.2013
CY11.09.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
SE11.09.2013
SI11.09.2013
GR12.12.2013
Former [2014/12]CY19.06.2013
FI11.09.2013
LT11.09.2013
LV11.09.2013
SE11.09.2013
SI11.09.2013
GR12.12.2013
Former [2014/11]CY19.06.2013
FI11.09.2013
LT11.09.2013
SE11.09.2013
Former [2014/10]CY19.06.2013
LT11.09.2013
SE11.09.2013
Former [2014/09]LT11.09.2013
SE11.09.2013
Former [2014/08]LT11.09.2013
Documents cited:Search[A]WO0175067  (HYSEQ INC [US], et al) [A] 1-2,4,7-10,12-13 * claim -; sequence 54085 *;
 [X]WO2004076622  (NAT INST OF ADVANCED IND SCIEN [JP], et al) [X] 1-2,4 * claim -; sequence 401 *;
 [XI]  - MORETTI P A B ET AL, "Molecular Cloning of a Human Vent-like Homeobox Gene", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, (20010801), vol. 76, no. 1-3, ISSN 0888-7543, pages 21 - 29, XP004459574 [X] 4,12-13 * the whole document * [I] 1-2,7-10

DOI:   http://dx.doi.org/10.1006/geno.2001.6574
 [XPI]  - ARSENI N ET AL, "The VENT-like homeobox gene VENTX2 is a novel candidate for a human hematopoietic regulatory protein", ANNALS OF HEMATOLOGY, & CONFERENCE ON ACUTE LEUKEMIAS XI - PROGNOSTIC FACTORS AND TREATMENT STRATEGIES; MUNICH, GERMANY; FEBRUARY 18 -22, 2006, (200602), vol. 85, no. Suppl. 1, ISSN 0939-5555, page 18, XP002557883 [XP] 4,12-13 * abstract * [I] 7-8
 [X]  - "Sequence 401 from Patent WO2004076622.", EMBL, (20040927), Database accession no. CQ873982, URL: EBI, XP002557884 [X] 1-2,4 * compound . *
 [X]  - LADHER R ET AL, "Xom: a Xenopus homeobox gene that mediates the early effects of BMP-4.", DEVELOPMENT (CAMBRIDGE, ENGLAND) AUG 1996, (199608), vol. 122, no. 8, ISSN 0950-1991, pages 2385 - 2394, XP002557885 [X] 4,12-13 * abstract *
 [A]  - MOREAU-AUBRY A ET AL, "A processed pseudogene codes for a new antigen recognized by a CD8<+> T cell clone on melanoma", JOURNAL OF EXPERIMENTAL MEDICINE 20000501 US, (20000501), vol. 191, no. 9, ISSN 0022-1007, pages 1617 - 1623, XP002557886 [A] 1-2,4,7-10,12-13 * the whole document *

DOI:   http://dx.doi.org/10.1084/jem.191.9.1617
 [A]  - GRIER D G ET AL, "The pathophysiology of HOX genes and their role in cancer", JOURNAL OF PATHOLOGY, (200501), vol. 205, no. 2, ISSN 0022-3417, pages 154 - 171, XP002557887 [A] 1-2,4,7-10,12-13 * the whole document *

DOI:   http://dx.doi.org/10.1002/path.1710
 [A]  - Geneseq, (20020218), Database accession no. ABG23726, URL: EBI, XP002557888 [A] 1-2,4,7-10,12-13 * compound . *
 [A]  - GAO HONG ET AL, "Regulation of Bmp4 signaling by phosphorylation dependent proteolysis of xom", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (200504), Database accession no. PREV200600211436, XP002557889 [A] 1-2,4,7-10,12-13 * abstract *
 [T]  - GAO HONG (JENNY) ET AL, "Hom-1 inhibits tumor growth in both p53 sufficient and deficient colon cancer cells", GASTROENTEROLOGY, & DIGESTIVE DISEASE WEEK MEETING/109TH ANNUAL MEETING OF THE AMERICAN-GASTROENTEROLOGICAL-ASSOCIATION; SAN DIEGO, CA, USA; MAY 17 22, 2008, (200804), vol. 134, no. 4, Suppl. 1, ISSN 0016-5085, page A744, XP002557890 [T] * abstract *

DOI:   http://dx.doi.org/10.1016/S0016-5085(08)63473-3
 [T]  - ARSENI NATALIA ET AL, "The vent-like homeobox gene VENTX2 is expressed in human hematopoietic progenitor cells and promotes human myeloid development in vitro and in vivo", BLOOD, & 49TH ANNUAL MEETING OF THE AMERICAN-SOCIETY-OF-HEMATOLOGY; ATLANTA, GA, USA; DECEMBER 08 -11, 2007, (200711), vol. 110, no. 11, Part 1, ISSN 0006-4971, pages 383A - 384A, XP002557891 [T] * abstract *
 [T]  - ARSENI N ET AL, "VENTX2 - A vent-like homeobox gene - Is a novel candidate for a hematopoietic regulatory protein", EXPERIMENTAL HEMATOLOGY (NEW YORK), & 36TH ANNUAL MEETING OF THE INTERNATIONAL-SOCIETY-FOR-EXPERIMENTAL-HEM ATOLOGY; HAMBURG, GERMANY; SEPTEMBER 28 -30, 2007, (200709), vol. 35, no. 9, Suppl. 2, ISSN 0301-472X, page 45, XP002557892 [T] * abstract *
 [T]  - ARSENI N ET AL, "The VENT-like homeobox gene ventx2 is expressed in human hematopotetic progenitor cells and promotes human myeloid development in vitro and in vivo", ANNALS OF HEMATOLOGY, & CONFERENCE ON ACUTE LEUKEMIAS XII - BIOLOGY AND TREATMENT STRATEGIES; MUNICH, GERMANY; FEBRUARY 16 -20, 2008, (200802), vol. 87, no. Suppl. 1, ISSN 0939-5555, page S15, XP002557893 [T] * abstract *
 [T]  - GAO HONG ET AL, "Xom interacts with and stimulates transcriptional activity of LEF1/TCFs: implications for ventral cell fate determination during vertebrate embryogenesis", CELL RESEARCH, (200704), vol. 17, no. 4, ISSN 1001-0602, pages 345 - 356, XP002557894 [T] * the whole document *

DOI:   http://dx.doi.org/10.1038/cr.2007.20
International search[X]US6544962  (JONES RICHARD E [US], et al)
by applicant   - G. M. ECCLESTON, APPLICATION OF EMULSION STABILITY THEORIES TO MOBILE AND SEMISOLID O/W EMULSIONS, COSMETICS & TOILETRIES, (199611), vol. 101, pages 73 - 92
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.