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Extract from the Register of European Patents

EP About this file: EP1996021

EP1996021 - COMPOSITIONS AND METHODS TO TREAT DISEASES CHARACTERIZED BY CELLULAR PROLIFERATION AND ANGIOGENESIS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.10.2018
Database last updated on 05.10.2024
FormerThe patent has been granted
Status updated on  10.11.2017
FormerGrant of patent is intended
Status updated on  23.02.2017
FormerExamination is in progress
Status updated on  31.01.2017
Most recent event   Tooltip05.06.2020Lapse of the patent in a contracting state
New state(s): HU, PT		published on 08.07.2020  [2020/28]
Applicant(s)For all designated states
Paloma Pharmaceuticals, Inc.
2150 East Lake Cook Road, Suite 750
Buffalo Grove, IL 60089 / US
[2015/21]
Former [2008/49]For all designated states
Paloma Pharmaceuticals, Inc.
37 Neillian Crescent
Jamaica Plain, MA 02130 / US
Inventor(s)01 / SHERRIS, David, I.
c/o Paloma Pharmaceuticals, Inc.
2150 East Lake Cook Road
Suite 750
Buffalo Grove, IL 60089 / US
02 / GILL, Manjinder
Niper Campus
Sector 67
SAS Nagar
Punjab, India 160062 / IN
03 / MA, Fupeng
315-1 Oak Grove Avenue
Melrose, MA 02176 / US
04 / KAUR BHAL, Sanjivanjit
448 Maple Avenue
Oakville, ON L6J 2J3 / CA
05 / FEHER, Miklos
229 West 60th Street
Apartment 22M
New York NY 10023 / US
06 / REDDEN, Peter
1273 Parkhurst Drive
Oakville, Ontario, L6M 3X3 / CA
07 / SCHMIDT, Jonathan
112 Wellington Road 7
Elora, Ontario N0B 1S0 / CA
08 / DUNN-DUFAULT, Robert
30 Marksam Road
Guelph, Ontario, N1H 1X2 / CA
 [2017/50]
Former [2015/44]01 / SHERRIS, David, I.
c/o Paloma Pharmaceuticals, Inc.
2150 East Lake Cook Road
Suite 750
Buffalo Grove, IL 60089 / US
02 / GILL, Manjinder
Niper Campus
Sector 67
SAS Nagar
Punjab, India 160062 / IN
03 / MA, Fupeng
315-1 Oak Grove Avenue
Melrose, MA 02176 / US
04 / KAUR BHAL, Sanjivanjit
448 Maple Avenue
Oakville, ON L6J 2J3 / CA
05 / FEHER, Miklos
229 West 60th Street
Apartment 22M
New York NY 10023 / US
06 / REDDEN, Peter
1273 Parkhurst Drive
Oakville
Ontario, L6M 3X3 / CA
07 / SCHMIDT, Jonathan
112 Wellington Road 7
Elora
Ontario N0B 1S0 / CA
08 / DUNN-DUFAULT, Robert
30 Marksam Road
Guelph
Ontario, N1H 1X2 / CA
Former [2015/21]01 / SHERRIS, David, I.
c/o Paloma Pharmaceuticals, Inc.
2150 East Lake Cook Road
Suite 750
Buffalo Grove, IL 60089 / US
Former [2008/49]01 / SHERRIS, David, I.
c/o Paloma Pharmaceuticals, Inc. 37 Neillian Crescent
Jamaica Plain, Massachusetts 02130 / US
Representative(s)FRKelly
Waterways House
Grand Canal Quay
Dublin D02 PD39 / IE
[N/P]
Former [2017/50]FRKelly
27 Clyde Road
Dublin D04 F838 / IE
Former [2008/49]Jennings, Tara Romaine, et al
F. R. Kelly & Co. 27 Clyde Road Ballsbridge
Dublin 4 / IE
Application number, filing date07757634.628.02.2007
[2008/49]
WO2007US62971
Priority number, dateUS20060777318P28.02.2006         Original published format: US 777318 P
US2006041261827.04.2006         Original published format: US 412618
[2008/49]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007101247
Date:07.09.2007
Language:EN
[2007/36]
Type: A2 Application without search report 
No.:EP1996021
Date:03.12.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 07.09.2007 takes the place of the publication of the European patent application.
[2008/49]
Type: B1 Patent specification 
No.:EP1996021
Date:13.12.2017
Language:EN
[2017/50]
Search report(s)International search report - published on:US13.12.2007
(Supplementary) European search report - dispatched on:EP03.03.2010
ClassificationIPC:A61K31/35, A01N43/16, A61K31/352, A61K31/353, A61K31/366, A61K31/382, A61K31/473, A61K31/517, C07D311/16, C07D311/18, C07D311/80, A61P35/00
[2016/42]
CPC:
C07D311/80 (EP,US); A61K31/192 (EP,US); A61K31/235 (EP,US);
A61K31/352 (EP,US); A61K31/353 (EP,US); A61K31/366 (EP,US);
A61K31/382 (EP,US); A61K31/4433 (EP,US); A61K31/473 (EP,US);
A61K31/517 (EP,US); A61K45/06 (EP,US); A61P1/04 (EP);
A61P15/08 (EP); A61P15/12 (EP); A61P17/00 (EP);
A61P17/02 (EP); A61P17/04 (EP); A61P17/06 (EP);
A61P19/02 (EP); A61P19/06 (EP); A61P19/10 (EP);
A61P25/04 (EP); A61P25/28 (EP); A61P27/02 (EP);
A61P29/00 (EP); A61P3/02 (EP); A61P31/00 (EP);
A61P31/04 (EP); A61P31/10 (EP); A61P31/12 (EP);
A61P31/18 (EP); A61P33/00 (EP); A61P35/00 (EP);
A61P35/02 (EP); A61P37/02 (EP); A61P37/08 (EP);
A61P43/00 (EP); A61P5/00 (EP); A61P7/00 (EP);
A61P7/06 (EP); A61P9/00 (EP); A61P9/10 (EP);
C07C65/40 (US); C07C69/78 (US); C07D239/90 (EP,US);
C07D311/16 (EP,US); C07D311/18 (EP,US); C07D405/06 (EP,US);
C07D405/12 (EP,US); Y02A50/30 (EP,US) (-)
C-Set:
A61K31/352, A61K2300/00 (EP,US);
A61K31/353, A61K2300/00 (US,EP);
A61K31/366, A61K2300/00 (US,EP);
A61K31/473, A61K2300/00 (US,EP);
A61K31/517, A61K2300/00 (EP,US)
(-)
Former IPC [2016/39]A61K31/35, A01N43/16, A61K31/352, A61K31/353, A61K31/366, A61K31/382, A61K31/473, A61K31/517, C07D311/16, C07D311/18, C07D311/80
Former IPC [2010/11]A61K31/35, A01N43/16, A61K31/352
Former IPC [2008/49]A01N43/16, A61K31/35
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2017/50]
Former [2008/49]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON DURCH ZELLULÄRE PROLIFERATION UND ANGIOGENESE VERMITTELTEN LEIDEN[2008/49]
English:COMPOSITIONS AND METHODS TO TREAT DISEASES CHARACTERIZED BY CELLULAR PROLIFERATION AND ANGIOGENESIS[2008/49]
French:COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE MALADIES CARACTÉRISÉES PAR LA PROLIFÉRATION CELLULAIRE ET L'ANGIOGENÈSE[2008/49]
Entry into regional phase29.09.2008National basic fee paid 
29.09.2008Search fee paid 
29.09.2008Designation fee(s) paid 
29.09.2008Examination fee paid 
Examination procedure18.09.2008Amendment by applicant (claims and/or description)
29.09.2008Examination requested  [2008/49]
14.06.2010Despatch of a communication from the examining division (Time limit: M06)
07.04.2011Reply to a communication from the examining division
24.09.2012Despatch of a communication from the examining division (Time limit: M06)
03.04.2013Reply to a communication from the examining division
09.08.2013Despatch of a communication from the examining division (Time limit: M06)
19.02.2014Reply to a communication from the examining division
24.11.2014Despatch of a communication from the examining division (Time limit: M04)
02.04.2015Reply to a communication from the examining division
10.08.2015Despatch of a communication from the examining division (Time limit: M06)
22.02.2016Reply to a communication from the examining division
22.09.2016Communication of intention to grant the patent
26.01.2017Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
24.02.2017Communication of intention to grant the patent
14.08.2017Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
23.10.2017Fee for grant paid
23.10.2017Fee for publishing/printing paid
23.10.2017Receipt of the translation of the claim(s)
Divisional application(s)EP12171834.0  / EP2543371
EP12171847.2  / EP2543367
EP12171867.0  / EP2545913
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  14.06.2010
Opposition(s)14.09.2018No opposition filed within time limit [2018/47]
Request for further processing for:23.10.2017Request for further processing filed
23.10.2017Full payment received (date of receipt of payment)
Request granted
08.11.2017Decision despatched
The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent
23.10.2017Request for further processing filed
23.10.2017Full payment received (date of receipt of payment)
Request granted
08.11.2017Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
07.04.2011Request for further processing filed
07.04.2011Full payment received (date of receipt of payment)
Request granted
26.04.2011Decision despatched
Fees paidRenewal fee
26.02.2009Renewal fee patent year 03
24.02.2010Renewal fee patent year 04
23.02.2011Renewal fee patent year 05
27.02.2012Renewal fee patent year 06
25.02.2013Renewal fee patent year 07
26.02.2014Renewal fee patent year 08
11.02.2015Renewal fee patent year 09
29.02.2016Renewal fee patent year 10
13.02.2017Renewal fee patent year 11
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU28.02.2007
AT13.12.2017
CY13.12.2017
CZ13.12.2017
DK13.12.2017
EE13.12.2017
ES13.12.2017
FI13.12.2017
IT13.12.2017
LT13.12.2017
LV13.12.2017
MC13.12.2017
NL13.12.2017
PL13.12.2017
PT13.12.2017
RO13.12.2017
SE13.12.2017
SI13.12.2017
SK13.12.2017
TR13.12.2017
BE28.02.2018
LU28.02.2018
BG13.03.2018
GR14.03.2018
IS13.04.2018
[2020/27]
Former [2020/16]AT13.12.2017
CY13.12.2017
CZ13.12.2017
DK13.12.2017
EE13.12.2017
ES13.12.2017
FI13.12.2017
IT13.12.2017
LT13.12.2017
LV13.12.2017
MC13.12.2017
NL13.12.2017
PL13.12.2017
RO13.12.2017
SE13.12.2017
SI13.12.2017
SK13.12.2017
TR13.12.2017
BE28.02.2018
LU28.02.2018
BG13.03.2018
GR14.03.2018
IS13.04.2018
Former [2019/12]AT13.12.2017
CY13.12.2017
CZ13.12.2017
DK13.12.2017
EE13.12.2017
ES13.12.2017
FI13.12.2017
IT13.12.2017
LT13.12.2017
LV13.12.2017
MC13.12.2017
NL13.12.2017
PL13.12.2017
RO13.12.2017
SE13.12.2017
SI13.12.2017
SK13.12.2017
BE28.02.2018
LU28.02.2018
BG13.03.2018
GR14.03.2018
IS13.04.2018
Former [2018/52]AT13.12.2017
CY13.12.2017
CZ13.12.2017
DK13.12.2017
EE13.12.2017
ES13.12.2017
FI13.12.2017
IT13.12.2017
LT13.12.2017
LV13.12.2017
MC13.12.2017
NL13.12.2017
PL13.12.2017
RO13.12.2017
SE13.12.2017
SK13.12.2017
LU28.02.2018
BG13.03.2018
GR14.03.2018
IS13.04.2018
Former [2018/51]AT13.12.2017
CY13.12.2017
CZ13.12.2017
DK13.12.2017
EE13.12.2017
ES13.12.2017
FI13.12.2017
IT13.12.2017
LT13.12.2017
LV13.12.2017
MC13.12.2017
NL13.12.2017
PL13.12.2017
RO13.12.2017
SE13.12.2017
SK13.12.2017
BG13.03.2018
GR14.03.2018
IS13.04.2018
Former [2018/44]AT13.12.2017
CY13.12.2017
CZ13.12.2017
EE13.12.2017
ES13.12.2017
FI13.12.2017
IT13.12.2017
LT13.12.2017
LV13.12.2017
MC13.12.2017
NL13.12.2017
PL13.12.2017
RO13.12.2017
SE13.12.2017
SK13.12.2017
BG13.03.2018
GR14.03.2018
IS13.04.2018
Former [2018/40]AT13.12.2017
CY13.12.2017
CZ13.12.2017
EE13.12.2017
ES13.12.2017
FI13.12.2017
IT13.12.2017
LT13.12.2017
LV13.12.2017
NL13.12.2017
PL13.12.2017
RO13.12.2017
SE13.12.2017
SK13.12.2017
BG13.03.2018
GR14.03.2018
IS13.04.2018
Former [2018/39]AT13.12.2017
CY13.12.2017
CZ13.12.2017
EE13.12.2017
ES13.12.2017
FI13.12.2017
IT13.12.2017
LT13.12.2017
LV13.12.2017
NL13.12.2017
PL13.12.2017
SE13.12.2017
SK13.12.2017
BG13.03.2018
GR14.03.2018
IS13.04.2018
Former [2018/38]AT13.12.2017
CY13.12.2017
CZ13.12.2017
EE13.12.2017
ES13.12.2017
FI13.12.2017
LT13.12.2017
LV13.12.2017
NL13.12.2017
PL13.12.2017
SE13.12.2017
SK13.12.2017
BG13.03.2018
GR14.03.2018
IS13.04.2018
Former [2018/37]CY13.12.2017
CZ13.12.2017
EE13.12.2017
ES13.12.2017
FI13.12.2017
LT13.12.2017
LV13.12.2017
NL13.12.2017
PL13.12.2017
SE13.12.2017
SK13.12.2017
BG13.03.2018
GR14.03.2018
Former [2018/34]FI13.12.2017
LT13.12.2017
LV13.12.2017
NL13.12.2017
SE13.12.2017
BG13.03.2018
GR14.03.2018
Former [2018/24]FI13.12.2017
LT13.12.2017
LV13.12.2017
SE13.12.2017
BG13.03.2018
GR14.03.2018
Former [2018/23]FI13.12.2017
LT13.12.2017
SE13.12.2017
GR14.03.2018
Former [2018/22]FI13.12.2017
LT13.12.2017
Documents cited:Search[X]US2002115711  (SCHMIDT JOHNATHAN MARTIN [CA], et al) [X] 1-15 * 0001; 0007; 0010; claim 1, claim 4; example 3; 0039; 0046 *;
 [PX]US2006257337  (SHERRIS DAVID [US]) [PX] 1-15 * example 1; table II; claim 7 *;
 [X]  - SCHMIDT J M ET AL, "Synthesis and evaluation of a novel nonsteroidal-specific endothelial cell proliferation inhibitor", JOURNAL OF MEDICINAL CHEMISTRY 20030410 US, (20030410), vol. 46, no. 8, ISSN 0022-2623, pages 1289 - 1292, XP002563534 [X] 1-15 * compounds 9a, 10; scheme 2; last of p. 1289 to second of p. 1290; penultimate of section "conclusion" on p. 1291 *

DOI:   http://dx.doi.org/10.1021/jm034007d
 [X]  - KENNER, G. W.; MURRAY, M. A.; TYLOR, C. M. B., "Oxidative cyclization of 2-biphenylcarboxylic acid", HCAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (1958), Database accession no. 1958:1811, URL: STN, XP002563536 [X] 1,5 * the whole document *
 [X]  - FARINA, VITTORIO ET AL, "The Stille reaction", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 2008:1383562, URL: STN, XP002563537 [X] 1,5 * abstract *
 [X]  - ADAMS, ROGER ET AL, "Structure of cannabinol. I. Preparation of an isomer, 3-hydroxy-1-amyl-6,6,9-trimethyl-6-dibenzopyran", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1940:43275, URL: STN, XP002563538 [X] 1,5 * abstract *
 [X]  - AOYAMA, NORIHITO; TAKENAKA, HIDEKI; MIIKE, AKIRA, "Coumarin derivatives for quantitative determination of peroxidation-active substances by chemiluminescence analysis", HCAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (19930805), Database accession no. 1993:577137, URL: STN, XP002563539 [X] 1,5 * the whole document *
 [X]  - RIGAUDY, JEAN ET AL, "Dehydration of meso-dihydroanthracene alcohols. 9,10-Dihydro-9-anthryl tertiary carbinols. A case of elimination (of water) according to Hofmann's rule", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1958:11057, URL: STN, XP002563540 [X] 1,5 * abstract *
 [X]  - GARAZD, YA. L. ET AL, "Modified Coumarins. 6. Synthesis of Substituted 5,6-Benzopsoralens", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 2003:73980, URL: STN, XP002563541 [X] 1,5 * abstract *
 [PA]  - LARROSA MAR ET AL, "Urolithins, ellagic acid-derived metabolites produced by human colonic microflora, exhibit estrogenic and antiestrogenic activities.", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 8 MAR 2006, (20060308), vol. 54, no. 5, ISSN 0021-8561, pages 1611 - 1620, XP002563535 [PA] 1-15 * fig. 3; p. 1615, col. 2 to p. 1616, col. 1 *

DOI:   http://dx.doi.org/10.1021/jf0527403
International search[X]US2005245490  (PINNEY KEVIN G [US], et al);
 [X]US2004242593  (MOORE BOB M [US], et al);
 [X]US6849757  (KAWAI MEGUMI [US], et al);
 [Y]US2004198750  (GREEN JEREMY [US], et al);
 [Y]US6908917  (ORTWINE DANIEL FRED [US])
ExaminationDE2459076
    - NOVAROLI ET AL, "Human recombinant monoamine oxidase B as reliable and efficient enzyme source for inhibitor screening", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB, (20051115), vol. 13, no. 22, doi:10.1016/J.BMC.2005.06.043, ISSN 0968-0896, pages 6212 - 6217, XP005098160

DOI:   http://dx.doi.org/10.1016/j.bmc.2005.06.043
by applicantUS2002115711
    - SCHMIDT J M ET AL., "Synthesis and evaluation of a novel nonsteroidal-specific endothelial cell proliferation inhibitor", JOURNAL OF MEDICINAL CHEMISTRY 20030410 US, (20030410), vol. 46, no. 8, pages 1289 - 1292
    - Remington's Pharmaceuticals Sciences
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.