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Extract from the Register of European Patents

EP About this file: EP1991706

EP1991706 - MICRORNA EXPRESSION PROFILE ASSOCIATED WITH PANCREATIC CANCER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  21.11.2014
Database last updated on 05.10.2024
Most recent event   Tooltip15.07.2016Lapse of the patent in a contracting state
New state(s): TR		published on 17.08.2016  [2016/33]
Applicant(s)For all designated states
The Ohio State University Research Foundation
1524 North High Street
Columbus, OH 43201-1063 / US
For all designated states
The Board of Regents of the University of Oklahoma
660 Parrington Oval
Norman, OK 73019 / US
[2013/30]
Former [2013/22]For all designated states
The Ohio State University Research Foundation
1524 North High Street
Columbus, OH 43201-1063 / US
For all designated states
Brackett, Daniel J.
2812 William Blvd.
Seminole, OK 74868 / US
Former [2012/24]For all designated states
The Ohio State University
1524 North High Street
Columbus, OH 43201 / US
Former [2011/02]For all designated states
The Ohio State University
1960 Kenny Road
Columbus, OH 43210 / US
Former [2008/47]For all designated states
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
1960 Kenny Road Columbus
Ohio 43120 / US
Inventor(s)01 / SCHMITTGEN, Thomas, D.
93 Alberry Drive
Granville, OH 43023 / US
02 / BRACKETT, Daniel, J.
2812 William Blvd.
Seminole, OK 74868 / US
 [2008/47]
Representative(s)Denison, Christopher Marcus, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [2014/03]Denison, Christopher Marcus, et al
Mewburn Ellis LLP
33 Gutter Lane
London
EC2V 8AS / GB
Former [2008/47]Denison, Christopher Marcus, et al
Mewburn Ellis LLP York House 23 Kingsway
London WC2B 6HP / GB
Application number, filing date07757822.702.03.2007
[2008/47]
WO2007US63208
Priority number, dateUS20060778271P02.03.2006         Original published format: US 778271 P
[2008/47]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007103808
Date:13.09.2007
Language:EN
[2007/37]
Type: A2 Application without search report 
No.:EP1991706
Date:19.11.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 13.09.2007 takes the place of the publication of the European patent application.
[2008/47]
Type: B1 Patent specification 
No.:EP1991706
Date:15.01.2014
Language:EN
[2014/03]
Search report(s)International search report - published on:US28.02.2008
(Supplementary) European search report - dispatched on:EP15.02.2010
ClassificationIPC:C12Q1/68, C07H21/02
[2008/47]
CPC:
C12Q1/6886 (EP,US); C12Q1/686 (US); A61P1/18 (EP);
A61P35/00 (EP); A61P35/04 (EP); A61P43/00 (EP);
C12Q1/6813 (US); C12Q1/6869 (US); C12Q2600/136 (EP,US);
C12Q2600/178 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/47]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:MIKRO-RNA-EXPRESSIONSPROFIL IM ZUSAMMENHANG MIT BAUCHSPEICHELDRÜSENKREBS[2008/47]
English:MICRORNA EXPRESSION PROFILE ASSOCIATED WITH PANCREATIC CANCER[2008/47]
French:PROFIL D'EXPRESSION DE MICRO-ARN ASSOCIÉ AU CANCER DU PANCRÉAS[2008/47]
Entry into regional phase19.09.2008National basic fee paid 
19.09.2008Search fee paid 
19.09.2008Designation fee(s) paid 
19.09.2008Examination fee paid 
Examination procedure19.09.2008Examination requested  [2008/47]
20.11.2008Amendment by applicant (claims and/or description)
11.05.2010Despatch of a communication from the examining division (Time limit: M06)
22.11.2010Reply to a communication from the examining division
01.06.2011Despatch of a communication from the examining division (Time limit: M06)
12.12.2011Reply to a communication from the examining division
30.08.2012Despatch of a communication from the examining division (Time limit: M06)
11.03.2013Reply to a communication from the examining division
21.03.2013Despatch of a communication from the examining division (Time limit: M01)
30.04.2013Reply to a communication from the examining division
14.05.2013Despatch of a communication from the examining division (Time limit: M02)
06.06.2013Reply to a communication from the examining division
09.08.2013Communication of intention to grant the patent
09.12.2013Fee for grant paid
09.12.2013Fee for publishing/printing paid
Divisional application(s)EP12168648.9  / EP2522746
EP12168652.1  / EP2522747
EP12168654.7  / EP2522748
EP12168655.4  / EP2522749
EP12168656.2  / EP2522750
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.05.2010
Opposition(s)16.10.2014No opposition filed within time limit [2014/52]
Fees paidRenewal fee
26.03.2009Renewal fee patent year 03
25.03.2010Renewal fee patent year 04
29.03.2011Renewal fee patent year 05
26.03.2012Renewal fee patent year 06
27.03.2013Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU02.03.2007
AT15.01.2014
BE15.01.2014
BG15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
MC15.01.2014
MT15.01.2014
NL15.01.2014
PL15.01.2014
RO15.01.2014
SE15.01.2014
SI15.01.2014
SK15.01.2014
TR15.01.2014
IE02.03.2014
LU02.03.2014
CH31.03.2014
LI31.03.2014
GR16.04.2014
IS15.05.2014
PT15.05.2014
[2016/33]
Former [2016/32]HU02.03.2007
AT15.01.2014
BE15.01.2014
BG15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
MC15.01.2014
MT15.01.2014
NL15.01.2014
PL15.01.2014
RO15.01.2014
SE15.01.2014
SI15.01.2014
SK15.01.2014
IE02.03.2014
LU02.03.2014
CH31.03.2014
LI31.03.2014
GR16.04.2014
IS15.05.2014
PT15.05.2014
Former [2016/28]AT15.01.2014
BE15.01.2014
BG15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
MC15.01.2014
MT15.01.2014
NL15.01.2014
PL15.01.2014
RO15.01.2014
SE15.01.2014
SI15.01.2014
SK15.01.2014
IE02.03.2014
LU02.03.2014
CH31.03.2014
LI31.03.2014
GR16.04.2014
IS15.05.2014
PT15.05.2014
Former [2016/27]AT15.01.2014
BE15.01.2014
BG15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
MC15.01.2014
MT15.01.2014
NL15.01.2014
PL15.01.2014
RO15.01.2014
SE15.01.2014
SI15.01.2014
SK15.01.2014
IE02.03.2014
LU02.03.2014
CH31.03.2014
LI31.03.2014
IS15.05.2014
PT15.05.2014
Former [2016/25]AT15.01.2014
BE15.01.2014
BG15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
MT15.01.2014
NL15.01.2014
PL15.01.2014
RO15.01.2014
SE15.01.2014
SI15.01.2014
SK15.01.2014
IE02.03.2014
LU02.03.2014
CH31.03.2014
LI31.03.2014
IS15.05.2014
PT15.05.2014
Former [2016/12]AT15.01.2014
BE15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
MT15.01.2014
NL15.01.2014
PL15.01.2014
RO15.01.2014
SE15.01.2014
SI15.01.2014
SK15.01.2014
IE02.03.2014
LU02.03.2014
CH31.03.2014
LI31.03.2014
IS15.05.2014
PT15.05.2014
Former [2015/24]AT15.01.2014
BE15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
NL15.01.2014
PL15.01.2014
RO15.01.2014
SE15.01.2014
SI15.01.2014
SK15.01.2014
IE02.03.2014
LU02.03.2014
CH31.03.2014
LI31.03.2014
IS15.05.2014
PT15.05.2014
Former [2015/08]AT15.01.2014
BE15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
NL15.01.2014
PL15.01.2014
RO15.01.2014
SE15.01.2014
SK15.01.2014
IE02.03.2014
LU02.03.2014
CH31.03.2014
LI31.03.2014
IS15.05.2014
PT15.05.2014
Former [2015/07]AT15.01.2014
BE15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
NL15.01.2014
PL15.01.2014
RO15.01.2014
SE15.01.2014
SK15.01.2014
IE02.03.2014
LU02.03.2014
IS15.05.2014
PT15.05.2014
Former [2014/50]AT15.01.2014
BE15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
NL15.01.2014
PL15.01.2014
RO15.01.2014
SE15.01.2014
SK15.01.2014
LU02.03.2014
IS15.05.2014
PT15.05.2014
Former [2014/49]AT15.01.2014
BE15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
NL15.01.2014
RO15.01.2014
SE15.01.2014
LU02.03.2014
IS15.05.2014
PT15.05.2014
Former [2014/48]AT15.01.2014
BE15.01.2014
CY15.01.2014
CZ15.01.2014
DK15.01.2014
EE15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
NL15.01.2014
SE15.01.2014
LU02.03.2014
IS15.05.2014
PT15.05.2014
Former [2014/41]AT15.01.2014
BE15.01.2014
CY15.01.2014
FI15.01.2014
LT15.01.2014
LV15.01.2014
NL15.01.2014
SE15.01.2014
IS15.05.2014
PT15.05.2014
Former [2014/39]AT15.01.2014
CY15.01.2014
FI15.01.2014
LT15.01.2014
NL15.01.2014
SE15.01.2014
IS15.05.2014
PT15.05.2014
Former [2014/37]AT15.01.2014
CY15.01.2014
FI15.01.2014
LT15.01.2014
SE15.01.2014
IS15.05.2014
PT15.05.2014
Former [2014/36]LT15.01.2014
IS15.05.2014
Documents cited:Search[X]WO2005078139  (UNIV JEFFERSON [US], et al) [X] 1-15* see whole doc. esp. claims *;
 [E]WO2007081680  (UNIV OHIO STATE RES FOUND [US], et al) [E] 1-15 * see whole doc. esp. claims and Table 3 *
International search[A]US2006019286  (HORVITZ H R [US], et al);
 [XP]US2006105360  (CROCE CARLO M [US], et al);
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DOI:   http://dx.doi.org/10.1093/nar/gki863
 [A]  - VOLINIA S. ET AL., "A microRNA expression signature of human solid tumors defines cancer gene targets", PROC. NATL. ACAD. SCI. USA, (20060214), vol. 103, no. 7, pages 2257 - 2261, XP002608380

DOI:   http://dx.doi.org/10.1073/PNAS.0510565103
 [XP]  - ROLDO C. ET AL., "MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologie: features and clinical behavior", J. CLIN. ONCOL., (20061010), vol. 24, no. 29, pages 4677 - 4684, XP008078235

DOI:   http://dx.doi.org/10.1200/JCO.2005.05.5194
by applicantUS4235871
 US4501728
 US4837028
 US4920016
 US4987071
 US5019369
 US5093246
 US5139941
 US5252479
 WO9324641
 WO9413788
 US5427916
 US5849902
 US2002086356
 US2004014113
 WO2004018176
 US2005277139
 US2006078924
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    - ROSTY, C. ET AL., HEMATOL ONCOL CLIN NORTH AM., (2002), vol. 16, pages 37 - 52
    - MATSUBAYASHI, H. ET AL., CLINICAL CANCER RESEARCH, (2005), vol. 11, pages 573 - 583
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    - GRIFFITHS-JONES, S., "The microRNA Registry", NUCLEIC ACIDS RES, (2004), vol. 32, no. 1, doi:doi:10.1093/nar/gkh023, pages D109 - 11, XP002392427

DOI:   http://dx.doi.org/10.1093/nar/gkh023
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 US20050656109
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.