Extract from the Register of European Patents

EP About this file: EP2027085

EP2027085 - PROSTAGLANDIN EP4 AGONISTS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  05.02.2016
Database last updated on 28.03.2026
Most recent event   Tooltip05.02.2016Application deemed to be withdrawnpublished on 09.03.2016  [2016/10]
Applicant(s)For all designated states
ALLERGAN, INC.
2525 Dupont Drive
Irvine, CA 92612 / US
[N/P]
Former [2009/09]For all designated states
ALLERGAN, INC.
2525 Dupont Drive
Irvine CA 92612 / US
Former [2008/36]For all designated states
Allergan Inc.
2525 Dupont Drive
Irvine, CA 92612 / US
Inventor(s)01 / IM, Wha, Bin
70 Palatine, Apt. 305
Irvine, CA 92612 / US
02 / BURK, Robert, M.
1337 Cerritos Drive
Laguna Beach, CA 92651 / US
03 / HOLOBOSKI, Mark
29342 Bobolink Drive
Laguna Niguel, CA 92677 / US
 [2009/09]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastrasse 30
81925 München / DE
[N/P]
Former [2009/09]HOFFMANN EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date07758870.520.03.2007
[2009/09]
WO2007US64360
Priority number, dateUS20060744234P04.04.2006         Original published format: US 744234 P
[2009/09]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007115001
Date:11.10.2007
Language:EN
[2007/41]
Type: A1 Application with search report 
No.:EP2027085
Date:25.02.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 11.10.2007 takes the place of the publication of the European patent application.
[2009/09]
Search report(s)International search report - published on:EP11.10.2007
ClassificationIPC:C07C405/00, A61K31/5575, A61P1/04
[2009/09]
CPC:
A61K31/5575 (EP,KR,US); C07C405/00 (EP,KR,US); C07D333/56 (EP,US);
A61P1/04 (EP); A61P43/00 (EP); C07D211/74 (EP,US);
C07D211/76 (EP,US); C07D333/62 (EP,US); C07D333/68 (EP,US);
C07D409/06 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/09]
TitleGerman:PROSTAGLANDIN-EP4-AGONISTEN[2009/09]
English:PROSTAGLANDIN EP4 AGONISTS[2009/09]
French:AGONISTES DE LA PROSTAGLANDINE EP4[2009/09]
Entry into regional phase22.10.2008National basic fee paid 
22.10.2008Designation fee(s) paid 
22.10.2008Examination fee paid 
Examination procedure22.10.2008Examination requested  [2009/09]
16.04.2009Despatch of a communication from the examining division (Time limit: M06)
26.10.2009Reply to a communication from the examining division
03.12.2010Despatch of a communication from the examining division (Time limit: M06)
27.05.2011Reply to a communication from the examining division
16.05.2012Despatch of a communication from the examining division (Time limit: M04)
17.09.2012Reply to a communication from the examining division
12.08.2013Despatch of a communication from the examining division (Time limit: M06)
12.02.2014Reply to a communication from the examining division
01.10.2015Application deemed to be withdrawn, date of legal effect  [2016/10]
26.10.2015Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2016/10]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  16.04.2009
Fees paidRenewal fee
26.03.2009Renewal fee patent year 03
25.03.2010Renewal fee patent year 04
29.03.2011Renewal fee patent year 05
26.03.2012Renewal fee patent year 06
27.03.2013Renewal fee patent year 07
27.03.2014Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.03.201509   M06   Not yet paid
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Cited inExaminationUS2006035963
 WO2004063158
 EP1481976
   CHOURASIA M K: "PHARMACEUTICAL APPROACHES TO COLON TARGETED DRUG DELIVERY SYSTEMS", JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, CANADIAN SOCIETY FOR PHARMACEUTICAL SCIENCES, EDMONTON, CA, vol. 6, no. 1, 1 January 2003 (2003-01-01), pages 33 - 66, XP008078133, ISSN: 1482-1826
   WIPF P ET AL: "SYNTHESIS OF CHEMOREVERSIBLE PRODRUGS OF ARA-C WITH VARIABLE TIME-RELEASE PROFILES, BIOLOGICAL EVALUATION OF THEIR APOPTOTIC ACTIVITY", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB, vol. 4, no. 10, 1 January 1996 (1996-01-01), pages 1585 - 1596, XP009066434, ISSN: 0968-0896, DOI: 10.1016/0968-0896(96)00153-8

DOI:   http://dx.doi.org/10.1016/0968-0896(96)00153-8
   "Prostaglandin tyrosine alkyl ester amides - prepd by reacting prostaglandin and tyrosine esters in presence of dicyclohexylcarbodiimide", DERWENT, XP002370551
   ANDERSON B D ET AL: "PROSTAGLANDIN PRODRUGS. VI: STRUCTURE-THERMODYNAMIC ACTIVITY AND STRUCTURE-AQUEOUS SOLUBILITY RELATIONSHIPS", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN PHARMACEUTICAL ASSOCIATION, WASHINGTON, US, vol. 69, no. 4, 1 April 1980 (1980-04-01), pages 424 - 430, XP008060923, ISSN: 0022-3549, DOI: 10.1002/JPS.2600690417

DOI:   http://dx.doi.org/10.1002/jps.2600690417
   SPRINGER C J ET AL: "Gene-directed enzyme prodrug therapy", 1 January 2002, ANTICANCER DRUG DEVELOPMENT, SAN DIEGO : ACADEMIC PRESS, PAGE(S) 137 - 155, ISBN: 0-12-072651-3, XP009159194
   MARUYAMA T ET AL: "DESIGN AND SYNTHESIS OF A SELECTIVE EP4-RECEPTOR AGONIST. PART 4: PRACTICAL SYNTHESIS AND BIOLOGICAL EVALUTION OF A NOVEL HIGHLY SELECTIVE EP4-RECEPTOR AGONIST", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB, vol. 10, 1 January 2002 (2002-01-01), pages 2103 - 2110, XP001222023, ISSN: 0968-0896, DOI: 10.1016/S0968-0896(02)00085-8

DOI:   http://dx.doi.org/10.1016/S0968-0896(02)00085-8
   KAJINO H ET AL: "An EP4 receptor agonist prevents indomethacin-induced closure of rat ductus arteriosus in vivo", PEDIATRIC RESEARCH, NATURE PUBLISHING GROUP, US, vol. 56, no. 4, 3 August 2004 (2004-08-03), pages 586 - 590, XP002370490, ISSN: 0031-3998, DOI: 10.1203/01.PDR.0000139409.25014.35

DOI:   http://dx.doi.org/10.1203/01.PDR.0000139409.25014.35
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