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Extract from the Register of European Patents

EP About this file: EP2048233

EP2048233 - MUTANT SepRS, AND METHOD FOR SITE-SPECIFIC INTRODUCTION OF PHOSPHOSERINE INTO PROTEIN BY USING THE SAME [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  21.09.2012
Database last updated on 12.10.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
Riken
2-1 Hirosawa
Wako-shi, Saitama 351-0198 / JP
[N/P]
Former [2011/51]For all designated states
Riken
2-1 Hirosawa
Wako-shi, Saitama 351-0198 / JP
Former [2009/16]For all designated states
Riken
2-1 Hirosawa
Wako-shi, Saitama 351-0198 / JP
For all designated states
The University of Tokyo
3-1, Hongo 7-chome Bunkyo-ku
Tokyo 113-8654 / JP
Inventor(s)01 / YOKOYAMA, Shigeyuki
c/o RIKEN Yokohama Institute, 7-22, Suehiro-cho 1-
chome, Tsurumi-ku, ;
Yokohama-shi, Kanagawa 2300045 / JP
02 / FUKUNAGA, Ryuya
c/o THE UNIVERSITY OF TOKYO, 3-1, Hongo 7-chome, B
unkyo-ku, ;
Tokyo 1138654 / JP
03 / SEKINE, Shun-ichi
c/o THE UNIVERSITY OF TOKYO, 3-1, Hongo 7-chome, B
unkyo-ku, ;
Tokyo 1138654 / JP
 [2011/46]
Former [2009/16]01 / YOKOYAMA, Shigeyuki
c/o RIKEN Yokohama Institute, 7-22, Suehiro-cho 1- chome, Tsurumi-ku, ;
Yokohama-shi, Kanagawa 2300045 / JP
02 / FUKUNAGA, Ryuya
c/o THE UNIVERSITY OF TOKYO, 3-1, Hongo 7-chome, B unkyo-ku, ;
Tokyo 1138654 / JP
03 / SEKINE, Shun-ichi
c/o THE UNIVERSITY OF TOKYO, 3-1, Hongo 7-chome, B unkyo-ku, ;
Tokyo 1138654 / JP
Representative(s)Arends, William Gerrit
Marks & Clerk LLP
15 Fetter Lane
London EC4A 1BW / GB
[N/P]
Former [2011/46]Arends, William Gerrit
Marks & Clerk LLP 90 Long Acre London
WC2E 9RA / GB
Former [2009/16]Arends, William Gerrit
Marks & Clerk LLP 90 Long Acre London
WC2E 9RA / GB
Application number, filing date07768165.828.06.2007
[2009/16]
WO2007JP63414
Priority number, dateJP2006017864228.06.2006         Original published format: JP 2006178642
[2009/16]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008001947
Date:03.01.2008
Language:JA
[2008/01]
Type: A1 Application with search report 
No.:EP2048233
Date:15.04.2009
Language:EN
[2009/16]
Type: B1 Patent specification 
No.:EP2048233
Date:16.11.2011
Language:EN
[2011/46]
Type: B8 Corrected title page of specification 
No.:EP2048233
Date:02.05.2012
[2012/18]
Search report(s)International search report - published on:JP03.01.2008
(Supplementary) European search report - dispatched on:EP31.05.2010
ClassificationIPC:C12N15/09, C12N9/00, C12P21/02
[2009/16]
CPC:
C12P21/02 (EP,US); C12N9/93 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/16]
TitleGerman:SEPRS-MUTANTE UND VERFAHREN ZUR STELLENGERICHTETEN EINFÜHRUNG VON PHOSPHOSERIN IN PROTEIN UNTER VERWENDUNG DAVON[2009/16]
English:MUTANT SepRS, AND METHOD FOR SITE-SPECIFIC INTRODUCTION OF PHOSPHOSERINE INTO PROTEIN BY USING THE SAME[2009/16]
French:SepRS MUTANTE, ET PROCÉDÉ D'INTRODUCTION SITO-SPÉCIFIQUE D'UNE PHOSPHOSÉRINE DANS UNE PROTÉINE EN UTILISANT CETTE SepRS[2009/16]
Entry into regional phase27.01.2009Translation filed 
26.01.2009National basic fee paid 
26.01.2009Search fee paid 
26.01.2009Designation fee(s) paid 
26.01.2009Examination fee paid 
Examination procedure27.01.2009Examination requested  [2009/16]
23.12.2010Amendment by applicant (claims and/or description)
17.05.2011Communication of intention to grant the patent
26.09.2011Fee for grant paid
26.09.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  17.05.2011
Opposition(s)17.08.2012No opposition filed within time limit [2012/43]
Fees paidRenewal fee
26.01.2009Renewal fee patent year 03
11.06.2010Renewal fee patent year 04
13.06.2011Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU28.06.2007
AT16.11.2011
BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
FI16.11.2011
IT16.11.2011
LT16.11.2011
LV16.11.2011
MT16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
TR16.11.2011
BG16.02.2012
GR17.02.2012
ES27.02.2012
IS16.03.2012
PT16.03.2012
IE28.06.2012
LU28.06.2012
MC30.06.2012
[2014/34]
Former [2014/27]AT16.11.2011
BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
FI16.11.2011
IT16.11.2011
LT16.11.2011
LV16.11.2011
MT16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
TR16.11.2011
BG16.02.2012
GR17.02.2012
ES27.02.2012
IS16.03.2012
PT16.03.2012
IE28.06.2012
LU28.06.2012
MC30.06.2012
Former [2014/21]AT16.11.2011
BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
FI16.11.2011
IT16.11.2011
LT16.11.2011
LV16.11.2011
MT16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
TR16.11.2011
BG16.02.2012
GR17.02.2012
ES27.02.2012
IS16.03.2012
PT16.03.2012
IE28.06.2012
MC30.06.2012
Former [2013/35]AT16.11.2011
BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
FI16.11.2011
IT16.11.2011
LT16.11.2011
LV16.11.2011
MT16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
BG16.02.2012
GR17.02.2012
ES27.02.2012
IS16.03.2012
PT16.03.2012
IE28.06.2012
MC30.06.2012
Former [2013/29]AT16.11.2011
BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
FI16.11.2011
IT16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
BG16.02.2012
GR17.02.2012
ES27.02.2012
IS16.03.2012
PT16.03.2012
IE28.06.2012
MC30.06.2012
Former [2013/22]AT16.11.2011
BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
IT16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
BG16.02.2012
GR17.02.2012
ES27.02.2012
IS16.03.2012
PT16.03.2012
IE28.06.2012
MC30.06.2012
Former [2013/20]AT16.11.2011
BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
IT16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
BG16.02.2012
GR17.02.2012
IS16.03.2012
PT16.03.2012
IE28.06.2012
MC30.06.2012
Former [2013/08]AT16.11.2011
BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
IT16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
BG16.02.2012
GR17.02.2012
IS16.03.2012
PT16.03.2012
MC30.06.2012
Former [2013/07]AT16.11.2011
BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
IT16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
BG16.02.2012
GR17.02.2012
IS16.03.2012
PT16.03.2012
Former [2012/37]BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
IT16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
BG16.02.2012
GR17.02.2012
IS16.03.2012
PT16.03.2012
Former [2012/36]BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
RO16.11.2011
SE16.11.2011
SI16.11.2011
SK16.11.2011
BG16.02.2012
GR17.02.2012
IS16.03.2012
PT16.03.2012
Former [2012/35]BE16.11.2011
CY16.11.2011
CZ16.11.2011
DK16.11.2011
EE16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
SE16.11.2011
SI16.11.2011
BG16.02.2012
GR17.02.2012
IS16.03.2012
PT16.03.2012
Former [2012/34]BE16.11.2011
CY16.11.2011
CZ16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
SE16.11.2011
SI16.11.2011
GR17.02.2012
IS16.03.2012
PT16.03.2012
Former [2012/28]BE16.11.2011
CY16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
SE16.11.2011
SI16.11.2011
GR17.02.2012
IS16.03.2012
PT16.03.2012
Former [2012/26]BE16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
PL16.11.2011
SE16.11.2011
SI16.11.2011
GR17.02.2012
IS16.03.2012
PT16.03.2012
Former [2012/25]BE16.11.2011
LT16.11.2011
LV16.11.2011
NL16.11.2011
SE16.11.2011
SI16.11.2011
GR17.02.2012
IS16.03.2012
PT16.03.2012
Former [2012/24]LT16.11.2011
LV16.11.2011
NL16.11.2011
SE16.11.2011
SI16.11.2011
GR17.02.2012
IS16.03.2012
PT16.03.2012
Former [2012/23]LT16.11.2011
NL16.11.2011
GR17.02.2012
IS16.03.2012
PT16.03.2012
Former [2012/21]LT16.11.2011
IS16.03.2012
Former [2012/20]LT16.11.2011
Documents cited:Search[T]  - FUKUNAGA R ET AL, "Phosphoserine aminoacylation of tRNA bearing an unnatural base anticodon", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US LNKD- DOI:10.1016/J.BBRC.2008.05.078, vol. 372, no. 3, ISSN 0006-291X, (20080801), pages 480 - 485, (20080527), XP022709964 [T] * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bbrc.2008.05.078
 [A]  - PERICH J W ET AL, "EFFICIENT SOLUTION-PHASE SYNTHESIS OF MULTIPLE O-PHOSPHOSERYL- CONTAINING PEPTIDES RELATED TO CASEIN AND STATHERIN", INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, MUNKSGAARD, COPENHAGEN, DK, (19920801), vol. 40, no. 2, ISSN 0367-8377, pages 81 - 88, XP000297256 [A] 1-15 * abstract * * page 81 - page 82, column l, paragraph 3 *
 [IA]  - WANG LEI ET AL, "EXPANDING THE GENETIC CODE", ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, ANNUAL REVIEWS INC., PALO ALTO, CA, US LNKD- DOI:10.1146/ANNUREV.BIOPHYS.35.101105.121507, (20060101), vol. 35, ISSN 1056-8700, pages 225 - 249, XP009084565 [I] 11 * the whole document * [A] 1-10,12-15

DOI:   http://dx.doi.org/10.1146/annurev.biophys.35.101105.121507
International search[A]WO03014354  (JAPAN SCIENCE & TECH CORP [JP], et al);
 [A]WO2004039989  (RIKEN [JP], et al);
 [Y]WO2004070024  (RIKEN [JP], et al);
 [A]JP2004537984  ;
 [XP]WO2006107813  (UNIV YALE [US], et al);
 [XP]  - FUKUNAGA R. ET AL., "Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea", NAT. STRUCT. MOL. BIOL., (20070311), vol. 14, no. 4, pages 272 - 279, XP003020797
 [Y]  - GENBANK, Database accession no. (NP_068951), XP003018750
 [A]  - KIGA D. ET AL., "Shifted positioning of the anticodon nucleotide residues of amber suppressor tRNA species by Escherichia coli arginyl-tRNA synthetase", EUR. J. BIOCHEM., (2001), vol. 268, no. 23, pages 6207 - 6213, XP003018751

DOI:   http://dx.doi.org/10.1046/j.0014-2956.2001.02570.x
 [A]  - SAKAMOTO K. ET AL., "Ikita Saibo de Chotanpakushitsu o Tsukuru - Hitennen Amino Acid o Tanpakushitsu ni Donyu suru Hoho", CHEMISTRY, (2005), vol. 60, no. 4, pages 70 - 71, XP003018752
 [A]  - SAUERWALD A. ET AL., "RNA-dependent cysteine biosynthesis in archaea", SCIENCE, (2005), vol. 307, no. 5717, pages 1969 - 1972, XP003018753

DOI:   http://dx.doi.org/10.1126/science.1108329
 [A]  - FUKUNAGA J. ET AL., "A base pair at the bottom of the anticodon stem is reciprocally preferred for discrimination of cognate tRNAs by Escherichia coli lysyl- and glutaminyl-tRNA synthetases", NUCLEIC ACIDS RES., (20060613), vol. 34, no. 10, pages 3181 - 3188, XP003018754

DOI:   http://dx.doi.org/10.1093/nar/gkl414
by applicantWO2004070024
 JP2006178642
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    - SAKAMOTO, K. ET AL., NUCLEIC ACIDS RESEARCH, (2002), vol. 30, pages 4692 - 4699
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    - COHEN, S.N. ET AL., PROC. NATL. ACAD. SCI., USA, (1972), vol. 69, pages 2110 - 2114
    - CLEMENS, M.J. ET AL., Transcription and Translation -A Practical Approach, IRL PRESS, O, (1984), pages 231 - 270
    - ZUBAY ET AL., ANN. REV. GENET., (1973), vol. 7, pages 267 - 287
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.