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Extract from the Register of European Patents

EP About this file: EP2057149

EP2057149 - PSEUDOBASE BENZO [C]PHENANTHRIDINES WITH IMPROVED EFFICACY, STABILITY, AND SAFETY [Right-click to bookmark this link]
Former [2009/20]PSEUDOBASE BENZO [C]PHENANTHRIDINES WITH IMPROVED EFFICACY, STABILITY, AND SAFETY
[2014/44]
StatusNo opposition filed within time limit
Status updated on  04.09.2015
Database last updated on 19.07.2024
Most recent event   Tooltip27.10.2017Lapse of the patent in a contracting state
New state(s): BE		published on 29.11.2017  [2017/48]
Applicant(s)For all designated states
Yale University
Two Whitney Avenue
New Haven, CT 06510 / US
[N/P]
Former [2014/41]For all designated states
Yale University
Two Whitney Avenue
New Haven, CT 06510 / US
Former [2009/20]For all designated states
Marinus Pharmaceuticals, Inc.
21 Business Park Drive
Brandford, CT 06405 / US
Inventor(s)01 / SHAW, Kenneth, R.
83 Steephill Road
Weston, CT 06883 / US
02 / ZHANG, Mingbao
75 Nyselius Place
Stamford, CT 06905 / US
 [2009/20]
Representative(s)Smaggasgale, Gillian Helen
WP Thompson
138 Fetter Lane
London EC4A 1BT / GB
[N/P]
Former [2014/44]Smaggasgale, Gillian Helen
WP Thompson
55 Drury Lane
London WC2B 5SQ / GB
Former [2009/20]Smaggasgale, Gillian Helen
W.P. Thompson & Co, 55 Drury Lane
London WC2B 5SQ / GB
Application number, filing date07810944.431.07.2007
[2014/44]
WO2007US17095
Priority number, dateUS20060834375P31.07.2006         Original published format: US 834375 P
[2009/20]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2008016596
Date:07.02.2008
Language:EN
[2008/06]
Type: A2 Application without search report 
No.:EP2057149
Date:13.05.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 07.02.2008 takes the place of the publication of the European patent application.
[2009/20]
Type: B1 Patent specification 
No.:EP2057149
Date:29.10.2014
Language:EN
[2014/44]
Search report(s)International search report - published on:EP10.04.2008
ClassificationIPC:C07D405/12, C07D317/70, A61K31/357
[2009/20]
CPC:
C07D491/04 (EP,US); A61P25/00 (EP); A61P25/18 (EP);
A61P29/00 (EP); A61P31/04 (EP); A61P31/10 (EP);
A61P31/12 (EP); A61P31/18 (EP); A61P35/00 (EP);
A61P43/00 (EP) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/20]
TitleGerman:PSEUDOBASISCHE BENZO-[C]-PHENANTHRIDINE MIT ERHÖHTER EFFIZIENZ, STABILITÄT UND SICHERHEIT[2014/44]
English:PSEUDOBASE BENZO [C]PHENANTHRIDINES WITH IMPROVED EFFICACY, STABILITY, AND SAFETY[2014/44]
French:BENZO[C]PHÉNANTHRIDINES PSEUDO-BASIQUES PRÉSENTANT UNE EFFICACITÉ, UNE STABILITÉ ET UNE INNOCUITÉ AMÉLIORÉES[2014/44]
Former [2009/20]PSEUDOBASISCHE BENZO-[C]-PHENANTHRIDINE MIT ERHÖHTER EFFIZIENZ, STABILITÄT UND SICHERHEIT
Former [2009/20]PSEUDOBASE BENZO [C]PHENANTHRIDINES WITH IMPROVED EFFICACY, STABILITY, AND SAFETY
Former [2009/20]BENZO[C]PHÉNANTHRIDINES PSEUDO-BASIQUES PRÉSENTANT UNE EFFICACITÉ, UNE STABILITÉ ET UNE INNOCUITÉ AMÉLIORÉES
Entry into regional phase27.02.2009National basic fee paid 
27.02.2009Designation fee(s) paid 
27.02.2009Examination fee paid 
Examination procedure27.02.2009Examination requested  [2009/20]
28.04.2009Amendment by applicant (claims and/or description)
04.06.2010Despatch of a communication from the examining division (Time limit: M06)
09.12.2010Reply to a communication from the examining division
26.11.2013Despatch of a communication from the examining division (Time limit: M04)
25.03.2014Reply to a communication from the examining division
16.05.2014Communication of intention to grant the patent
15.09.2014Fee for grant paid
15.09.2014Fee for publishing/printing paid
15.09.2014Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  04.06.2010
Opposition(s)30.07.2015No opposition filed within time limit [2015/41]
Fees paidRenewal fee
28.07.2009Renewal fee patent year 03
26.07.2010Renewal fee patent year 04
25.07.2011Renewal fee patent year 05
25.07.2012Renewal fee patent year 06
29.07.2013Renewal fee patent year 07
28.07.2014Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU31.07.2007
AT29.10.2014
BE29.10.2014
BG29.10.2014
CY29.10.2014
CZ29.10.2014
DK29.10.2014
EE29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
MC29.10.2014
MT29.10.2014
NL29.10.2014
PL29.10.2014
RO29.10.2014
SE29.10.2014
SI29.10.2014
SK29.10.2014
TR29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
[2017/46]
Former [2017/39]HU31.07.2007
AT29.10.2014
BG29.10.2014
CY29.10.2014
CZ29.10.2014
DK29.10.2014
EE29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
MC29.10.2014
MT29.10.2014
NL29.10.2014
PL29.10.2014
RO29.10.2014
SE29.10.2014
SI29.10.2014
SK29.10.2014
TR29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2017/22]AT29.10.2014
CY29.10.2014
CZ29.10.2014
DK29.10.2014
EE29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
MC29.10.2014
MT29.10.2014
NL29.10.2014
PL29.10.2014
RO29.10.2014
SE29.10.2014
SI29.10.2014
SK29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2016/13]AT29.10.2014
CY29.10.2014
CZ29.10.2014
DK29.10.2014
EE29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
MC29.10.2014
NL29.10.2014
PL29.10.2014
RO29.10.2014
SE29.10.2014
SI29.10.2014
SK29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2016/12]AT29.10.2014
CY29.10.2014
CZ29.10.2014
DK29.10.2014
EE29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
NL29.10.2014
PL29.10.2014
RO29.10.2014
SE29.10.2014
SI29.10.2014
SK29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2015/37]AT29.10.2014
CY29.10.2014
CZ29.10.2014
DK29.10.2014
EE29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
NL29.10.2014
PL29.10.2014
RO29.10.2014
SE29.10.2014
SK29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2015/36]AT29.10.2014
CY29.10.2014
CZ29.10.2014
DK29.10.2014
EE29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
NL29.10.2014
PL29.10.2014
RO29.10.2014
SE29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2015/35]AT29.10.2014
CY29.10.2014
DK29.10.2014
EE29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
NL29.10.2014
PL29.10.2014
SE29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2015/34]AT29.10.2014
CY29.10.2014
DK29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
NL29.10.2014
PL29.10.2014
SE29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2015/26]AT29.10.2014
CY29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
NL29.10.2014
PL29.10.2014
SE29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2015/25]AT29.10.2014
FI29.10.2014
LT29.10.2014
LV29.10.2014
NL29.10.2014
PL29.10.2014
SE29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2015/24]FI29.10.2014
LT29.10.2014
LV29.10.2014
NL29.10.2014
PL29.10.2014
SE29.10.2014
GR30.01.2015
IS28.02.2015
PT02.03.2015
Former [2015/23]FI29.10.2014
LT29.10.2014
NL29.10.2014
IS28.02.2015
PT02.03.2015
Former [2015/22]LT29.10.2014
PT02.03.2015
Former [2015/20]LT29.10.2014
Cited inInternational search[X]US3912740  (ZEE-CHENG KWANG YUEN, et al) [X] 1-34 * claim 1 *;
 [XY]  - FRANK R. STERMITZ ET AL, "Some Structural Relationship among Cytotoxic and Antitumor Benzophenanthridine Alkaloid Derivatives", JOURNAL OF MEDICINAL CHEMISTRY, (1973), vol. 16, no. 8, pages 939 - 940, XP002464866 [X] 1,4-9,24-29,32,33 * compounds 5D,7D * * the whole document * [Y] 1-34

DOI:   http://dx.doi.org/10.1021/jm00266a016
 [Y]  - ZEE-CHENG R K-Y ET AL, "PREPARATION AND ANTILEUKEMIC ACTIVITY OF SOME ALKOXYBENZOÚC PHENANTHRIDINIUM SALTS AND CORRESPONDING DIHYDRO DERIVATIVES", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1975), vol. 18, no. 1, ISSN 0022-2623, pages 66 - 71, XP000653117 [Y] 1-34 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm00235a015
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.