Extract from the Register of European Patents

EP About this file: EP2094636

EP2094636 - PROCESS FOR PREPARING 1-(2-ETHYL-BUTYL)-CYCLOHEXANECARBOXYLIC ACID [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  30.08.2013
Database last updated on 09.04.2026
Most recent event   Tooltip01.08.2014Lapse of the patent in a contracting state
New state(s): LT
published on 03.09.2014  [2014/36]
Applicant(s)For all designated states
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[N/P]
Former [2009/36]For all designated states
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
Inventor(s)01 / HOFFMANN, Ursula
Baselstrasse 40L
4132 Muttenz / CH
02 / LOHRI, Bruno
Scheltenstrasse 5
4153 Reinach / CH
 [2009/36]
Representative(s)Heiroth, Ulrike Hildegard
F. Hoffmann-La Roche AG
Patent Department
Grenzacherstrasse 124
4070 Basel / CH
[N/P]
Former [2012/43]Heiroth, Ulrike Hildegard
F. Hoffmann-La Roche AG Patent Department, Grenzacherstrasse 124
CH-4070 Basel / CH
Former [2009/36]Heiroth, Ulrike Hildegard
F. Hoffmann-La Roche AG Patent Department, Grenzacherstrasse 124
CH-4070 Basel / CH
Application number, filing date07848018.310.12.2007
[2009/36]
WO2007EP63582
Priority number, dateEP2006012672420.12.2006         Original published format: EP 06126724
[2009/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008074677
Date:26.06.2008
Language:EN
[2008/26]
Type: A1 Application with search report 
No.:EP2094636
Date:02.09.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 26.06.2008 takes the place of the publication of the European patent application.
[2009/36]
Type: B1 Patent specification 
No.:EP2094636
Date:24.10.2012
Language:EN
[2012/43]
Search report(s)International search report - published on:EP26.06.2008
ClassificationIPC:C07C319/22, C07C323/40, C07C51/48, C07C51/353, C07C61/08, C07C319/06, C07C319/20, C07C327/30, C07C321/24, C07C321/28, C07C51/60
[2012/22]
CPC:
C07C323/40 (EP,US); C07C51/353 (EP,KR,US); C07C319/06 (EP,US);
C07C319/22 (EP,US); C07C327/30 (EP,KR,US); C07C49/80 (KR);
C07C51/48 (EP,US); C07C61/08 (KR); C07C2601/14 (EP,US) (-)
C-Set:
C07C51/353, C07C61/08 (EP,US);
C07C51/48, C07C61/08 (US,EP)
Former IPC [2009/36]C07C51/353, C07C61/08, C07C319/06, C07C319/20, C07C327/30, C07C321/24, C07C321/28, C07C51/60
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/36]
TitleGerman:VERFAHREN ZUR HERSTELLUNG VON 1-(-2-ETHYLBUTYL)-CYCLOHEXANCARBONSÄURE[2009/36]
English:PROCESS FOR PREPARING 1-(2-ETHYL-BUTYL)-CYCLOHEXANECARBOXYLIC ACID[2009/36]
French:PROCEDE DE PREPARATION DE L'ACIDE 1-(2-ETHYL-BUTYL)-CYCLOHEXANE CARBOXYLIQUE[2009/36]
Entry into regional phase20.07.2009National basic fee paid 
20.07.2009Designation fee(s) paid 
20.07.2009Examination fee paid 
Examination procedure01.07.2008Request for preliminary examination filed
International Preliminary Examining Authority: EP
20.07.2009Examination requested  [2009/36]
10.08.2009Amendment by applicant (claims and/or description)
01.02.2010Despatch of a communication from the examining division (Time limit: M06)
06.08.2010Reply to a communication from the examining division
16.04.2012Cancellation of oral proceeding that was planned for 14.05.2012
14.05.2012Date of oral proceedings (cancelled)
18.05.2012Communication of intention to grant the patent
04.09.2012Fee for grant paid
04.09.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  01.02.2010
Opposition(s)25.07.2013No opposition filed within time limit [2013/40]
Fees paidRenewal fee
07.12.2009Renewal fee patent year 03
22.11.2010Renewal fee patent year 04
07.12.2011Renewal fee patent year 05
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Lapses during opposition  TooltipHU10.12.2007
AT24.10.2012
BE24.10.2012
CY24.10.2012
CZ24.10.2012
DK24.10.2012
EE24.10.2012
FI24.10.2012
LT24.10.2012
LV24.10.2012
MT24.10.2012
NL24.10.2012
PL24.10.2012
RO24.10.2012
SE24.10.2012
SI24.10.2012
SK24.10.2012
IE10.12.2012
LU10.12.2012
MC31.12.2012
BG24.01.2013
GR25.01.2013
IS24.02.2013
PT25.02.2013
[2014/36]
Former [2014/34]HU10.12.2007
AT24.10.2012
BE24.10.2012
CY24.10.2012
CZ24.10.2012
DK24.10.2012
EE24.10.2012
FI24.10.2012
LV24.10.2012
MT24.10.2012
NL24.10.2012
PL24.10.2012
RO24.10.2012
SE24.10.2012
SI24.10.2012
SK24.10.2012
IE10.12.2012
LU10.12.2012
MC31.12.2012
BG24.01.2013
GR25.01.2013
IS24.02.2013
PT25.02.2013
Former [2014/27]AT24.10.2012
BE24.10.2012
CY24.10.2012
CZ24.10.2012
DK24.10.2012
EE24.10.2012
FI24.10.2012
LV24.10.2012
MT24.10.2012
NL24.10.2012
PL24.10.2012
RO24.10.2012
SE24.10.2012
SI24.10.2012
SK24.10.2012
IE10.12.2012
LU10.12.2012
MC31.12.2012
BG24.01.2013
GR25.01.2013
IS24.02.2013
PT25.02.2013
Former [2013/51]AT24.10.2012
BE24.10.2012
CY24.10.2012
CZ24.10.2012
DK24.10.2012
EE24.10.2012
FI24.10.2012
LV24.10.2012
MT24.10.2012
NL24.10.2012
PL24.10.2012
RO24.10.2012
SE24.10.2012
SI24.10.2012
SK24.10.2012
IE10.12.2012
MC31.12.2012
BG24.01.2013
GR25.01.2013
IS24.02.2013
PT25.02.2013
Former [2013/47]AT24.10.2012
BE24.10.2012
CY24.10.2012
CZ24.10.2012
DK24.10.2012
EE24.10.2012
FI24.10.2012
LV24.10.2012
NL24.10.2012
PL24.10.2012
RO24.10.2012
SE24.10.2012
SI24.10.2012
SK24.10.2012
IE10.12.2012
MC31.12.2012
BG24.01.2013
GR25.01.2013
IS24.02.2013
PT25.02.2013
Former [2013/37]AT24.10.2012
BE24.10.2012
CY24.10.2012
CZ24.10.2012
DK24.10.2012
EE24.10.2012
FI24.10.2012
LV24.10.2012
NL24.10.2012
PL24.10.2012
RO24.10.2012
SE24.10.2012
SI24.10.2012
SK24.10.2012
MC31.12.2012
BG24.01.2013
GR25.01.2013
IS24.02.2013
PT25.02.2013
Former [2013/35]AT24.10.2012
BE24.10.2012
CY24.10.2012
CZ24.10.2012
DK24.10.2012
EE24.10.2012
FI24.10.2012
LV24.10.2012
NL24.10.2012
PL24.10.2012
SE24.10.2012
SI24.10.2012
SK24.10.2012
MC31.12.2012
BG24.01.2013
GR25.01.2013
IS24.02.2013
PT25.02.2013
Former [2013/34]AT24.10.2012
BE24.10.2012
CY24.10.2012
DK24.10.2012
FI24.10.2012
LV24.10.2012
NL24.10.2012
PL24.10.2012
SE24.10.2012
SI24.10.2012
MC31.12.2012
BG24.01.2013
GR25.01.2013
IS24.02.2013
PT25.02.2013
Former [2013/33]AT24.10.2012
BE24.10.2012
CY24.10.2012
FI24.10.2012
LV24.10.2012
NL24.10.2012
PL24.10.2012
SE24.10.2012
SI24.10.2012
MC31.12.2012
GR25.01.2013
IS24.02.2013
PT25.02.2013
Former [2013/31]AT24.10.2012
BE24.10.2012
CY24.10.2012
FI24.10.2012
LV24.10.2012
NL24.10.2012
PL24.10.2012
SE24.10.2012
SI24.10.2012
GR25.01.2013
IS24.02.2013
PT25.02.2013
Former [2013/28]BE24.10.2012
CY24.10.2012
FI24.10.2012
LV24.10.2012
NL24.10.2012
PL24.10.2012
SE24.10.2012
SI24.10.2012
GR25.01.2013
IS24.02.2013
PT25.02.2013
Former [2013/26]BE24.10.2012
CY24.10.2012
FI24.10.2012
LV24.10.2012
NL24.10.2012
PL24.10.2012
SE24.10.2012
SI24.10.2012
GR25.01.2013
IS24.02.2013
Former [2013/24]BE24.10.2012
CY24.10.2012
FI24.10.2012
LV24.10.2012
NL24.10.2012
PL24.10.2012
SE24.10.2012
GR25.01.2013
IS24.02.2013
Former [2013/23]CY24.10.2012
FI24.10.2012
LV24.10.2012
NL24.10.2012
PL24.10.2012
SE24.10.2012
IS24.02.2013
Former [2013/22]FI24.10.2012
NL24.10.2012
SE24.10.2012
IS24.02.2013
Former [2013/21]SE24.10.2012
Cited inInternational search[Y]   B.D. ROTH ET AL: "Inhibitors of acyl-CoA:Cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents", J.MED.CHEM., vol. 35, no. 9, 1992, pages 1609 - 1617, XP002437815 [Y] 1-24 * page 1610; figure III * * page 1612, column L, paragraph 1; table III *

DOI:   http://dx.doi.org/10.1021/jm00087a016
 [Y]   P.L. CREGER: "Metalated carboxylic acids. III. Monoalkylation of alkylacetic acids. A possible alternative to the malonic ester synthesis for the preparation of dialkylacetic acids", J.AM.CHEM.SOC., vol. 92, no. 5, 1970, pages 1397 - 1398, XP002437816 [Y] 1-19,24 * table I * * page 1398, column 2, paragraph L *

DOI:   http://dx.doi.org/10.1021/ja00708a049
 [DY]   SHINKAI HISASHI ET AL: "Bis[2-(Acylamino)phenyl] Disulfides, 2-(Acylamino)benzenethiols, and S-[2-(Acylamino)phenyl] Alkanethioates as Novel Inhibitors of Cholesteryl Ester Transfer Protein", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 43, 2000, pages 3566 - 3572, XP002288180, ISSN: 0022-2623 [DY] 20-23 * schemes 1 and 2 * * example - *

DOI:   http://dx.doi.org/10.1021/jm000224s
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