blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

Italy joins the Federated Register

Click here for more information on the Federated Register.

2025-06-12

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register User Manual
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2098237

EP2098237 - ANALGESIC AGENT COMPRISING CYCLIC PHOSPHATIDIC ACID DERIVATIVE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  05.07.2013
Database last updated on 11.04.2026
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
Ochanomizu University
2-1-1, Otsuka, Bunkyo-ku
Tokyo 112-8610 / JP
[N/P]
Former [2012/35]For all designated states
Ochanomizu University
2-1-1, Otsuka, Bunkyo-ku
Tokyo 1128610 / JP
Former [2009/37]For all designated states
Ochanomizu University
2-1-1, Otsuka, Bunkyo-ku
Tokyo 1128610 / JP
Inventor(s)01 / MUROFUSHI, Kimiko
5-52-13-803 Higashi-ikebukuro
Toshima-ku
Tokyo 170-0013 / JP
02 / KANASHIKI, Harumi
1-15-6-208 Kaga
Itabashi-ku
Tokyo 173-0003 / JP
 [2012/35]
Former [2009/37]01 / MUROFUSHI, Kimiko
5-52-13-803 Higashi-ikebukuro Toshima-ku
Tokyo 170-0013 / JP
02 / KANASHIKI, Harumi
1-15-6-208 Kaga Itabashi-ku
Tokyo 173-0003 / JP
Representative(s)polypatent
An den Gärten 7
51491 Overath / DE
[N/P]
Former [2012/02]Polypatent
An den Gärten 7
51491 Overath / DE
Former [2010/01]Polypatent
Postfach 40 02 43
51410 Bergisch Gladbach / DE
Former [2009/37]Polypatent
An den Gärten 7
51491 Overath / DE
Application number, filing date07849882.125.12.2007
[2009/37]
WO2007JP01463
Priority number, dateJP2006035364228.12.2006         Original published format: JP 2006353642
[2009/37]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008081580
Date:10.07.2008
Language:JA
[2008/28]
Type: A1 Application with search report 
No.:EP2098237
Date:09.09.2009
Language:EN
[2009/37]
Type: B1 Patent specification 
No.:EP2098237
Date:29.08.2012
Language:EN
[2012/35]
Search report(s)International search report - published on:JP10.07.2008
(Supplementary) European search report - dispatched on:EP25.01.2010
ClassificationIPC:A61K31/665, A61P25/04, A61P29/00
[2009/37]
CPC:
A61K31/665 (EP,KR,US); A61P25/04 (EP); A61P29/00 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/37]
TitleGerman:ANALGETISCHES MITTEL MIT EINEM CYCLISCHEN PHOSPHATIDINSÄUREDERIVAT[2009/37]
English:ANALGESIC AGENT COMPRISING CYCLIC PHOSPHATIDIC ACID DERIVATIVE[2009/37]
French:AGENT ANALGÉSIQUE COMPRENANT UN DÉRIVÉ CYCLIQUE D'ACIDE PHOSPHATIDIQUE[2009/37]
Entry into regional phase25.05.2009Translation filed 
25.05.2009National basic fee paid 
25.05.2009Search fee paid 
25.05.2009Designation fee(s) paid 
25.05.2009Examination fee paid 
Examination procedure25.05.2009Examination requested  [2009/37]
19.04.2010Despatch of a communication from the examining division (Time limit: M04)
26.08.2010Reply to a communication from the examining division
18.02.2011Despatch of a communication from the examining division (Time limit: M04)
15.06.2011Reply to a communication from the examining division
13.03.2012Communication of intention to grant the patent
19.07.2012Fee for grant paid
19.07.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  19.04.2010
Opposition(s)30.05.2013No opposition filed within time limit [2013/32]
Fees paidRenewal fee
11.12.2009Renewal fee patent year 03
15.12.2010Renewal fee patent year 04
12.12.2011Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU25.12.2007
AT29.08.2012
BE29.08.2012
CY29.08.2012
CZ29.08.2012
DK29.08.2012
EE29.08.2012
FI29.08.2012
IT29.08.2012
LT29.08.2012
LV29.08.2012
MT29.08.2012
NL29.08.2012
PL29.08.2012
RO29.08.2012
SE29.08.2012
SI29.08.2012
SK29.08.2012
TR29.08.2012
BG29.11.2012
GR30.11.2012
ES10.12.2012
IE25.12.2012
LU25.12.2012
IS29.12.2012
CH31.12.2012
LI31.12.2012
MC31.12.2012
PT31.12.2012
[2014/34]
Former [2014/27]AT29.08.2012
BE29.08.2012
CY29.08.2012
CZ29.08.2012
DK29.08.2012
EE29.08.2012
FI29.08.2012
IT29.08.2012
LT29.08.2012
LV29.08.2012
MT29.08.2012
NL29.08.2012
PL29.08.2012
RO29.08.2012
SE29.08.2012
SI29.08.2012
SK29.08.2012
TR29.08.2012
BG29.11.2012
GR30.11.2012
ES10.12.2012
IE25.12.2012
LU25.12.2012
IS29.12.2012
CH31.12.2012
LI31.12.2012
MC31.12.2012
PT31.12.2012
Former [2014/21]AT29.08.2012
BE29.08.2012
CY29.08.2012
CZ29.08.2012
DK29.08.2012
EE29.08.2012
FI29.08.2012
IT29.08.2012
LT29.08.2012
LV29.08.2012
MT29.08.2012
NL29.08.2012
PL29.08.2012
RO29.08.2012
SE29.08.2012
SI29.08.2012
SK29.08.2012
TR29.08.2012
BG29.11.2012
GR30.11.2012
ES10.12.2012
IE25.12.2012
IS29.12.2012
CH31.12.2012
LI31.12.2012
MC31.12.2012
PT31.12.2012
Former [2013/51]AT29.08.2012
BE29.08.2012
CY29.08.2012
CZ29.08.2012
DK29.08.2012
EE29.08.2012
FI29.08.2012
IT29.08.2012
LT29.08.2012
LV29.08.2012
MT29.08.2012
NL29.08.2012
PL29.08.2012
RO29.08.2012
SE29.08.2012
SI29.08.2012
SK29.08.2012
BG29.11.2012
GR30.11.2012
ES10.12.2012
IE25.12.2012
IS29.12.2012
CH31.12.2012
LI31.12.2012
MC31.12.2012
PT31.12.2012
Former [2013/48]AT29.08.2012
BE29.08.2012
CY29.08.2012
CZ29.08.2012
DK29.08.2012
EE29.08.2012
FI29.08.2012
IT29.08.2012
LT29.08.2012
LV29.08.2012
NL29.08.2012
PL29.08.2012
RO29.08.2012
SE29.08.2012
SI29.08.2012
SK29.08.2012
BG29.11.2012
GR30.11.2012
ES10.12.2012
IE25.12.2012
IS29.12.2012
CH31.12.2012
LI31.12.2012
MC31.12.2012
PT31.12.2012
Former [2013/47]AT29.08.2012
BE29.08.2012
CY29.08.2012
CZ29.08.2012
DK29.08.2012
EE29.08.2012
FI29.08.2012
IT29.08.2012
LT29.08.2012
LV29.08.2012
NL29.08.2012
PL29.08.2012
RO29.08.2012
SE29.08.2012
SI29.08.2012
SK29.08.2012
BG29.11.2012
GR30.11.2012
ES10.12.2012
IE25.12.2012
IS29.12.2012
MC31.12.2012
PT31.12.2012
Former [2013/34]AT29.08.2012
BE29.08.2012
CY29.08.2012
CZ29.08.2012
DK29.08.2012
EE29.08.2012
FI29.08.2012
IT29.08.2012
LT29.08.2012
LV29.08.2012
NL29.08.2012
PL29.08.2012
RO29.08.2012
SE29.08.2012
SI29.08.2012
SK29.08.2012
BG29.11.2012
GR30.11.2012
ES10.12.2012
IS29.12.2012
MC31.12.2012
PT31.12.2012
Former [2013/33]AT29.08.2012
BE29.08.2012
CY29.08.2012
CZ29.08.2012
DK29.08.2012
EE29.08.2012
FI29.08.2012
IT29.08.2012
LT29.08.2012
LV29.08.2012
NL29.08.2012
PL29.08.2012
RO29.08.2012
SE29.08.2012
SI29.08.2012
SK29.08.2012
GR30.11.2012
ES10.12.2012
IS29.12.2012
MC31.12.2012
PT31.12.2012
Former [2013/23]AT29.08.2012
BE29.08.2012
CY29.08.2012
CZ29.08.2012
DK29.08.2012
EE29.08.2012
FI29.08.2012
IT29.08.2012
LT29.08.2012
LV29.08.2012
NL29.08.2012
PL29.08.2012
RO29.08.2012
SE29.08.2012
SI29.08.2012
SK29.08.2012
GR30.11.2012
ES10.12.2012
IS29.12.2012
PT31.12.2012
Former [2013/22]AT29.08.2012
BE29.08.2012
CY29.08.2012
CZ29.08.2012
DK29.08.2012
EE29.08.2012
FI29.08.2012
LT29.08.2012
LV29.08.2012
NL29.08.2012
SE29.08.2012
SI29.08.2012
GR30.11.2012
ES10.12.2012
IS29.12.2012
PT31.12.2012
Former [2013/21]AT29.08.2012
BE29.08.2012
CY29.08.2012
DK29.08.2012
FI29.08.2012
LT29.08.2012
LV29.08.2012
SE29.08.2012
SI29.08.2012
GR30.11.2012
IS29.12.2012
PT31.12.2012
Former [2013/13]AT29.08.2012
BE29.08.2012
CY29.08.2012
FI29.08.2012
LT29.08.2012
LV29.08.2012
SE29.08.2012
SI29.08.2012
GR30.11.2012
IS29.12.2012
PT31.12.2012
Former [2013/12]AT29.08.2012
BE29.08.2012
CY29.08.2012
FI29.08.2012
LT29.08.2012
LV29.08.2012
SE29.08.2012
SI29.08.2012
GR30.11.2012
IS29.12.2012
Former [2013/11]AT29.08.2012
CY29.08.2012
FI29.08.2012
LT29.08.2012
LV29.08.2012
SI29.08.2012
GR30.11.2012
IS29.12.2012
Former [2013/10]AT29.08.2012
CY29.08.2012
FI29.08.2012
LT29.08.2012
IS29.12.2012
Former [2013/09]AT29.08.2012
FI29.08.2012
LT29.08.2012
Former [2013/08]AT29.08.2012
LT29.08.2012
Former [2013/07]AT29.08.2012
Documents cited:Search[X]   MURAKAMI-MUROFUSHI K ET AL: "Biological functions of a novel lipid mediator, cyclic phosphatidic acid", BIOCHIMICA AND BIOPHYSICA ACTA. MOLECULAR AND CELL BIOLOGY OFLIPIDS, ELSEVIER, AMSTERDAM, NL, vol. 1582, no. 1-3, 23 May 2002 (2002-05-23), pages 1 - 7, XP004366516, ISSN: 1388-1981 [X] 1-4 * figures 7,11 * * page 5, column 2, paragraph 2 - page 6, column 1, paragraph 1 *

DOI:   http://dx.doi.org/10.1016/S1388-1981(02)00131-2
 [DA]   UCHIDA S; SUZUKI A; HOTTA H; SATO A: "The effects of morphine on supraspinal and propriospinal somatocardiac reflexes in anesthetized rats", NEUROSCIENCE LETTERS, vol. 269, no. 3, 16 July 1999 (1999-07-16), IRELAND, pages 161 - 164, XP002556141 [DA] 1-4 * page 164, column 1, paragraph 3 * * abstract * * page 162; figure 1 *

DOI:   http://dx.doi.org/10.1016/S0304-3940(99)00444-9
 [A]   HEFTI F F ET AL: "Novel class of pain drugs based on antagonism of NGF", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER, HAYWARTH, GB, vol. 27, no. 2, 1 February 2006 (2006-02-01), pages 85 - 91, XP025029541, ISSN: 0165-6147, [retrieved on 20060201] [A] 1-4 * abstract * * page 85, column 1, paragraph 1 * * page 86, column 1, paragraph 2 - page 87, column 1, paragraph 1 *

DOI:   http://dx.doi.org/10.1016/j.tips.2005.12.001
 [A]   FUJIWARA YUKO; SEBK AGNES; MEAKIN SUSAN; KOBAYASHI TETSUYUKI; MURAKAMI-MUROFUSHI KIMIKO; TIGYI GABOR: "Cyclic phosphatidic acid elicits neurotrophin-like actions in embryonic hippocampal neurons", JOURNAL OF NEUROCHEMISTRY, vol. 87, no. 5, December 2003 (2003-12-01), England, pages 1272 - 1283, XP002556142 [A] 1-4 * the whole document * * page 1273 * * page 1275 *

DOI:   http://dx.doi.org/10.1046/j.1471-4159.2003.02106.x
 [A]   PARK ET AL: "Lipid mediators of sensitivity in sensory neurons", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER, HAYWARTH, GB, vol. 26, no. 11, 1 November 2005 (2005-11-01), pages 571 - 577, XP005129125, ISSN: 0165-6147 [A] 1-4 * abstract * * page 574, column 2, paragraph 4 - page 575, column 1, paragraph 2 *

DOI:   http://dx.doi.org/10.1016/j.tips.2005.09.010
by applicantJPH11367032
   MURAKAMI-MUROFUSHI, K. ET AL., J. BIOL. CHEM., vol. 267, 1992, pages 21512 - 21517
   MURAKAMI-MUROFUSHI, K. ET AL., BIOCHEM. BIOPHYS. ACTA, vol. 1258, 1995, pages 57 - 60
   KOBAYASHI, T. ET AL., LIFE SCI., vol. 65, 1999, pages 2185 - 2191
   KOBAYASHI, S. ET AL., TETRAHEDRON LETTERS, vol. 34, 1993, pages 4047 - 4050
   "The Pharmaceutical Society of Japan, The 23rd Symposium of Advancement of Reaction and Synthesis", SYNTHESIS AND PHYSIOLOGICAL EFFECTS OF CYCLIC PHOSPHATIDIC ACID AND CARBA DERIVATIVE, 17 November 1997 (1997-11-17), pages 101 - 104
   UCHIDA ET AL., NEUROSCI LETT, vol. 269, 1999, pages 161
   SATO ET AL., J AUTON NERV SYST, vol. 4, 1981, pages 231
   KOBAYASHI, S. ET AL., TETRAHEDRON LETT., vol. 34, 1993, pages 4047 - 4050
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.