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Extract from the Register of European Patents

EP About this file: EP2094681

EP2094681 - INDOL-4-YL-PYRIMIDINYL-2-YL-AMINE DERIVATIVES AND USE THEREOF AS CYCLIN DEPENDANT KINASE INHIBITORS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  25.02.2011
Database last updated on 15.11.2024
Most recent event   Tooltip25.02.2011Application deemed to be withdrawnpublished on 30.03.2011  [2011/13]
Applicant(s)For all designated states
Novartis AG
Lichtstrasse 35
4056 Basel / CH
[N/P]
Former [2009/36]For all designated states
NOVARTIS AG
Lichtstrasse 35
4056 Basel / CH
Inventor(s)01 / BECKWITH, Rohan Eric John
250 Massachusetts Avenue
Cambridge, Massachusetts 02139 / US
 [2009/36]
Representative(s)Vögeli-Lange, Regina
Novartis Pharma AG
Patent Department
4002 Basel / CH
[N/P]
Former [2009/36]Vögeli-Lange, Regina
Novartis Pharma AG Patent Department
4002 Basel / CH
Application number, filing date07865903.420.12.2007
[2009/36]
WO2007US88267
Priority number, dateUS20060871469P22.12.2006         Original published format: US 871469 P
[2009/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008079918
Date:03.07.2008
Language:EN
[2008/27]
Type: A1 Application with search report 
No.:EP2094681
Date:02.09.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 03.07.2008 takes the place of the publication of the European patent application.
[2009/36]
Search report(s)International search report - published on:EP03.07.2008
ClassificationIPC:C07D401/04, C07D403/04, C07D403/14, C07D471/04, C07D487/04, A61K31/506, A61P35/00
[2009/36]
CPC:
C07D403/04 (EP,US); C07D487/04 (EP,KR,US); A61K31/506 (KR);
A61P13/12 (EP); A61P17/02 (EP); A61P25/00 (EP);
A61P29/00 (EP); A61P3/10 (EP); A61P31/12 (EP);
A61P31/14 (EP); A61P31/18 (EP); A61P35/00 (EP);
A61P37/06 (EP); A61P43/00 (EP); C07D401/04 (EP,US);
C07D401/14 (EP,US); C07D403/14 (EP,US); C07D417/14 (EP,US);
C07D471/04 (EP,KR,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/36]
TitleGerman:INDOL-4-YLPYRIMIDINYL-2-YL-AMINDERIVATE UND DEREN VERWENDUNG ALS INHIBITOREN DER CYCLINABHÄNGIGEN KINASE[2009/36]
English:INDOL-4-YL-PYRIMIDINYL-2-YL-AMINE DERIVATIVES AND USE THEREOF AS CYCLIN DEPENDANT KINASE INHIBITORS[2009/36]
French:DÉRIVÉS D'INDOL-4-YL-PYRIMIDINYL-2-YL-AMINE ET LEUR UTILISATION COMME INHIBITEURS DE LA KINASE DÉPENDANTE DES CYCLINES[2009/36]
Entry into regional phase22.07.2009National basic fee paid 
22.07.2009Designation fee(s) paid 
22.07.2009Examination fee paid 
Examination procedure22.07.2009Examination requested  [2009/36]
07.09.2009Amendment by applicant (claims and/or description)
23.03.2010Despatch of a communication from the examining division (Time limit: M06)
05.10.2010Application deemed to be withdrawn, date of legal effect  [2011/13]
10.11.2010Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2011/13]
Fees paidRenewal fee
11.12.2009Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.12.201004   M06   Not yet paid
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Cited inInternational search[X]WO9744326  (HOFFMANN LA ROCHE [CH]) [X] 1-12* compounds on page 59, lines 23-34 compound on page 63, lines 29-30 compounds on page 69, lines 30-33 *;
 [X]WO2005065074  (UNIV TEMPLE [US], et al) [X] 1-20 * compound on page 21, lines 16-17 *;
 [X]WO2006124863  (IRM LLC [US], et al) [X] 1-12,21-50 * claims 1,7 * * examples on pages 23-43 *;
 [X]US2006270686  (KELLY MARTHA [US], et al) [X] 1-50 * claims 1,133 * * example 31 *;
 [PX]WO2007042810  (LUDWIG INST CANCER RES [CH], et al) [PX] 1-12 * claims 1,10 * * compounds I4 on page 43, K4 on page 44 and M4 on page 45 *;
 [PX]  - HUANG ET AL, "Synthesis and biological study of 2-amino-4-aryl-5-chloropyrimidine analogues as inhibitors of VEGFR-2 and cyclin dependent kinase 1 (CDK1)", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, (20070330), vol. 17, no. 8, ISSN 0960-894X, pages 2179 - 2183, XP022009228 [PX] 1-50 * abstract * * compound 9d, table 2 *

DOI:   http://dx.doi.org/10.1016/j.bmcl.2007.01.086
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.