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Extract from the Register of European Patents

EP About this file: EP2114909

EP2114909 - PROCESS FOR THE SYNTHESIS OF DERIVATIVES OF 3-AMINO-TETRAHYDROFURAN-3-CARBOXYLIC ACID AND USE THEREOF AS MEDICAMENTS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  01.03.2013
Database last updated on 25.09.2024
Most recent event   Tooltip01.03.2013Application deemed to be withdrawnpublished on 03.04.2013  [2013/14]
Applicant(s)For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HU  IE  IS  IT  LI  LT  LU  LV  MC  MT  NL  PL  PT  RO  SE  SI  SK  TR 
Boehringer Ingelheim International GmbH
Binger Strasse 173
55216 Ingelheim am Rhein / DE
For:DE 
Boehringer Ingelheim Pharma GmbH & Co. KG
Binger Strasse 173
55216 Ingelheim am Rhein / DE
[N/P]
Former [2009/46]For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HU  IE  IS  IT  LI  LT  LU  LV  MC  MT  NL  PL  PT  RO  SE  SI  SK  TR 
Boehringer Ingelheim International GmbH
Binger Strasse 173
55216 Ingelheim am Rhein / DE
For:DE 
Boehringer Ingelheim Pharma GmbH & Co. KG
Binger Strasse 173
55216 Ingelheim am Rhein / DE
Inventor(s)01 / HAN, Zhengxu
c/o Boehringer Ingelheim Pharmaceuticals, Inc. 900 Ridgebury Road P.O. Box 368
Ridgefield, Connecticut 06877-0368 / US
02 / GERLACH, Kai
Ayestrasse 37
88441 Mittelbiberach / DE
03 / KRISHNAMURTHY, Dhileepkumar
c/o Boehringer Ingelheim Pharmaceuticals, Inc. 900 Ridgebury Road P.O. Box 368
Ridgefield, Connecticut 06877-0368 / US
04 / MATTHES, Burkhard
Rathausstrasse 9
88410 Bad Wurzach / DE
05 / NAR, Herbert
Hexenweg 19
88416 Ochsenhausen / DE
06 / PRIEPKE, Henning
Pfluggasse 15
88400 Biberach / DE
07 / SCHULER-METZ, Annette
Birkenharderstr. 11
88447 Warthausen / DE
08 / SENANAYAKE, Chris H.
Holzgasse 7
89081 Ulm / DE
09 / SIEGER, Peter
c/o Boehringer Ingelheim Pharmaceuticals, Inc. 900 Ridgebury Road P.O. Box 368
Ridgefield, Connecticut 06877-0368 / US
10 / TANG, Wenjun
Klingenaecker 7
88441 Mittelbiberach / DE
11 / WIENEN, Wolfgang
c/o Boehringer Ingelheim Pharmaceuticals, Inc. 900 Ridgebury Road P.O. Box 368
Ridgefield, Connecticut 06877-0368 / US
12 / XU, Yibo
Kirschenweg 27
88400 Biberach / DE
13 / YEE, Nathan K.
c/o Boehringer Ingelheim Pharmaceuticals, Inc. 900 Ridgebury Road P.O. Box 368
Ridgefield, Connecticut 06877-0368 / US
 [2009/46]
Representative(s)Simon, Elke Anna Maria, et al
Boehringer Ingelheim GmbH
Binger Strasse 173
55216 Ingelheim am Rhein / DE
[2012/40]
Former [2009/48]Hammann, Heinz, et al
Boehringer Ingelheim GmbH CD-Patents Binger Strasse 173
55216 Ingelheim am Rhein / DE
Former [2009/46]Hammann, Heinz, et al
Boehringer Ingelheim GmbH CD Patents Binger Strasse 173
55216 Ingelheim Am Rhein / DE
Application number, filing date07866298.821.12.2007
[2009/46]
WO2007EP64406
Priority number, dateUS20060882937P31.12.2006         Original published format: US 882937 P
[2009/46]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2008080891
Date:10.07.2008
Language:EN
[2008/28]
Type: A2 Application without search report 
No.:EP2114909
Date:11.11.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 10.07.2008 takes the place of the publication of the European patent application.
[2009/46]
Search report(s)International search report - published on:EP02.10.2008
ClassificationIPC:C07D307/24, C07D409/14, C07D413/14
[2009/46]
CPC:
C07D409/14 (EP,KR,US); C07D413/14 (EP,KR,US); A61P43/00 (EP);
A61P7/02 (EP); C07D307/24 (EP,KR,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/46]
Extension statesBA31.07.2009
HR31.07.2009
RS31.07.2009
TitleGerman:VERFAHREN ZUR SYNTHESE VON DERIVATEN VON 3-AMINO-TETRAHYDROFURAN-3-CARBOXYLSÄURE UND IHRE VERWENDUNG ALS MEDIKAMENTE[2009/46]
English:PROCESS FOR THE SYNTHESIS OF DERIVATIVES OF 3-AMINO-TETRAHYDROFURAN-3-CARBOXYLIC ACID AND USE THEREOF AS MEDICAMENTS[2009/46]
French:PROCÉDÉ DE SYNTHÈSE DE DÉRIVÉS DE L'ACIDE 3-AMINO-TÉTRAHYDROFURAN-3-CARBOXYLIQUE ET UTILISATION DE CEUX-CI EN TANT QUE MÉDICAMENTS[2009/46]
Entry into regional phase31.07.2009National basic fee paid 
31.07.2009Designation fee(s) paid 
31.07.2009Examination fee paid 
Examination procedure31.07.2009Examination requested  [2009/46]
11.09.2009Amendment by applicant (claims and/or description)
28.06.2010Despatch of a communication from the examining division (Time limit: M06)
21.04.2011Reply to a communication from the examining division
18.05.2011Despatch of a communication from the examining division (Time limit: M06)
13.03.2012Reply to a communication from the examining division
29.03.2012Despatch of a communication from the examining division (Time limit: M06)
09.10.2012Application deemed to be withdrawn, date of legal effect  [2013/14]
14.11.2012Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2013/14]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  28.06.2010
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
13.03.2012Request for further processing filed
13.03.2012Full payment received (date of receipt of payment)
Request granted
27.03.2012Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
21.04.2011Request for further processing filed
21.04.2011Full payment received (date of receipt of payment)
Request granted
19.05.2011Decision despatched
Fees paidRenewal fee
04.01.2010Renewal fee patent year 03
03.01.2011Renewal fee patent year 04
02.01.2012Renewal fee patent year 05
02.01.2013Renewal fee patent year 06
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Cited inInternational search[A]WO2005111014  (BOEHRINGER INGELHEIM INT [DE], et al) [A] 1-23,27-29 * page 138; claims 1-17; compounds 17, 18 *;
 [A]WO2005111029  (BOEHRINGER INGELHEIM INT [DE], et al) [A] 1-23,27-29 * page 178; examples 34,48; claims 1-15; compounds 21, 22 *;
 [A]WO2006034822  (BOEHRINGER INGELHEIM INT [DE], et al) [A] 1-23,27-29 * examples 2,13 *;
 [AX]  - LAVRADOR, KARINE ET AL, "A new series of cyclic amino acids as inhibitors of S-adenosyl L-methionine synthetase", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , 8(13), 1629-1634 CODEN: BMCLE8; ISSN: 0960-894X, (1998), XP002475921 [A] 1-23,27-29 * the whole document * * Scheme 2, compounds Ia-c, IIa-c * [X] 24-26

DOI:   http://dx.doi.org/10.1016/S0960-894X(98)00267-4
Examination   - BHUSHAN RAVI ET AL, "Resolution of Enantiomers of Ibuprofen by Liquid Chromatography: A Review", BIOMEDICAL CHROMATOGRAPHY, JOHN WILEY & SONS LTD, GB, (19981101), vol. 12, no. 6, ISSN 0269-3879, pages 309 - 316, XP002668423

DOI:   http://dx.doi.org/10.1002/(SICI)1099-0801(199811/12)12:6<309::AID-BMC763>3.0.CO;2-K
    - GÜBITZ G, "Separation of Drug Enantiomers by HPLC Using Chiral Stationary Phases A Selective Review", CHROMATOGRAPHIA, VIEWEG UND TEUBNER VERLAG, DE, (19901101), vol. 30, no. 9-10, ISSN 0009-5893, pages 555 - 564, XP002668422

DOI:   http://dx.doi.org/10.1007/BF02269804
    - ASHOK K PEEPLIWAL ET AL, "A Review: Stereochemical consideration and eudismic ratio in chiral drug development", JOURNAL OF BIOMEDICAL SCIENCES AND RESEARCH, PHARMA INFO PUBLICATIONS, IN, (20100101), vol. 2, no. 1, ISSN 0975-542X, pages 29 - 45, XP007915083
by applicantWO2005111014
 WO2005111029
 WO2006034822
    - KARINE LAVRADOR, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, (1998), vol. 8, no. 13, pages 1629 - 1634
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.